Bus San Diego to San Antonio, TX: Compare prices and save money

Compare all timetables for the bus from San Diego to San Antonio, TX

Here is a selection of the cheapest bus trips from the schedule from San Diego to San Antonio, TX from various bus operators like FlixBus or Greyhound US for the next days.

today

$152

tomorrow

$154

Saturday

Sunday

$129

Monday

$150

Tuesday

$144

Wednesday

$129

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	33h 15m	1:10 PM	San Diego	Seaport Village	12:25 AM	San Antonio, TX	Bus Station		Economy	$152	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 9/10/2026 1:10:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/12/2026 12:25:00 AM. 50 Economy ticket for $152 per person are available. Travel duration is 33h 15m
	Greyhound US	39h 10m	7:45 PM	San Diego	Old Town Transit Center	12:55 PM	San Antonio, TX	Bus Station		Economy	$179	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 9/10/2026 7:45:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/12/2026 12:55:00 PM. 50 Economy ticket for $179 per person are available. Travel duration is 39h 10m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	33h 15m	1:10 PM	San Diego	Seaport Village	12:25 AM	San Antonio, TX	Bus Station	Economy	$154	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 9/11/2026 1:10:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/13/2026 12:25:00 AM. 50 Economy ticket for $154 per person are available. Travel duration is 33h 15m
FlixBus	37h 0m	9:25 AM	San Diego	Old Town Transit Center	12:25 AM	San Antonio, TX	Bus Station	Economy	$156	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 9/11/2026 9:25:00 AM to Bus Station, San Antonio, TX (USA) arriving at 9/13/2026 12:25:00 AM. 50 Economy ticket for $156 per person are available. Travel duration is 37h 0m
Greyhound US	36h 5m	9:50 AM	San Diego	Old Town Transit Center	11:55 PM	San Antonio, TX	Bus Station	Economy	$156	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 9/11/2026 9:50:00 AM to Bus Station, San Antonio, TX (USA) arriving at 9/12/2026 11:55:00 PM. 50 Economy ticket for $156 per person are available. Travel duration is 36h 5m
FlixBus	32h 50m	1:35 PM	San Diego	La Jolla Village	12:25 AM	San Antonio, TX	Bus Station	Economy	$158	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 9/11/2026 1:35:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/13/2026 12:25:00 AM. 50 Economy ticket for $158 per person are available. Travel duration is 32h 50m
Greyhound US	39h 10m	7:45 PM	San Diego	Old Town Transit Center	12:55 PM	San Antonio, TX	Bus Station	Economy	$167	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 9/11/2026 7:45:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/13/2026 12:55:00 PM. 50 Economy ticket for $167 per person are available. Travel duration is 39h 10m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	37h 0m	9:25 AM	San Diego	Old Town Transit Center	12:25 AM	San Antonio, TX	Bus Station	Economy	$129	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 9/13/2026 9:25:00 AM to Bus Station, San Antonio, TX (USA) arriving at 9/15/2026 12:25:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 37h 0m
FlixBus	33h 15m	1:10 PM	San Diego	Seaport Village	12:25 AM	San Antonio, TX	Bus Station	Economy	$130	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 9/13/2026 1:10:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/15/2026 12:25:00 AM. 50 Economy ticket for $130 per person are available. Travel duration is 33h 15m
FlixBus	32h 50m	1:35 PM	San Diego	La Jolla Village	12:25 AM	San Antonio, TX	Bus Station	Economy	$133	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 9/13/2026 1:35:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/15/2026 12:25:00 AM. 50 Economy ticket for $133 per person are available. Travel duration is 32h 50m
Greyhound US	36h 15m	9:50 AM	San Diego	Old Town Transit Center	12:05 AM	San Antonio, TX	Bus Station	Economy	$136	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 9/13/2026 9:50:00 AM to Bus Station, San Antonio, TX (USA) arriving at 9/15/2026 12:05:00 AM. 50 Economy ticket for $136 per person are available. Travel duration is 36h 15m
Greyhound US	39h 10m	7:45 PM	San Diego	Old Town Transit Center	12:55 PM	San Antonio, TX	Bus Station	Economy	$142	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 9/13/2026 7:45:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/15/2026 12:55:00 PM. 50 Economy ticket for $142 per person are available. Travel duration is 39h 10m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	37h 0m	9:25 AM	San Diego	Old Town Transit Center	12:25 AM	San Antonio, TX	Bus Station	Economy	$150	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 9/14/2026 9:25:00 AM to Bus Station, San Antonio, TX (USA) arriving at 9/16/2026 12:25:00 AM. 50 Economy ticket for $150 per person are available. Travel duration is 37h 0m
FlixBus	33h 15m	1:10 PM	San Diego	Seaport Village	12:25 AM	San Antonio, TX	Bus Station	Economy	$150	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 9/14/2026 1:10:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/16/2026 12:25:00 AM. 50 Economy ticket for $150 per person are available. Travel duration is 33h 15m
Greyhound US	36h 15m	9:50 AM	San Diego	Old Town Transit Center	12:05 AM	San Antonio, TX	Bus Station	Economy	$155	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 9/14/2026 9:50:00 AM to Bus Station, San Antonio, TX (USA) arriving at 9/16/2026 12:05:00 AM. 50 Economy ticket for $155 per person are available. Travel duration is 36h 15m
Greyhound US	39h 10m	7:45 PM	San Diego	Old Town Transit Center	12:55 PM	San Antonio, TX	Bus Station	Economy	$161	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 9/14/2026 7:45:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/16/2026 12:55:00 PM. 50 Economy ticket for $161 per person are available. Travel duration is 39h 10m

Did you know that if you travel from San Diego to San Antonio, TX via Calexico, CA, you can save more than $20? You can find the corresponding connections below.
- Greyhound US
  
  36h 35m
  
  0
  
  9:50 AM
  
  San Diego
  Old Town Transit Center
  
  12:35 PM
  
  Calexico, CA
  Bus Station
  
  0
  
  Economy
  
  $25
  
  A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 9/13/2026 9:50:00 AM to Bus Station, Calexico, CA (USA) arriving at 9/13/2026 12:35:00 PM. 50 Economy ticket for $25 per person are available. Travel duration is 2h 45m
- FlixBus
  
  27h 15m
  
  0
  
  7:10 PM
  
  Calexico, CA
  Bus Station
  
  12:25 AM
  
  San Antonio, TX
  Bus Station
  
  0
  
  Economy
  
  $105
  
  A Bus from FlixBus goes from Bus Station, Calexico, CA (USA) at 9/13/2026 7:10:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/15/2026 12:25:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 27h 15m
Travel time is 1h 20m longer, but you will save $20

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	33h 15m	1:10 PM	San Diego	Seaport Village	12:25 AM	San Antonio, TX	Bus Station	Economy	$144	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 9/15/2026 1:10:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/17/2026 12:25:00 AM. 50 Economy ticket for $144 per person are available. Travel duration is 33h 15m
FlixBus	32h 50m	1:35 PM	San Diego	La Jolla Village	12:25 AM	San Antonio, TX	Bus Station	Economy	$144	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 9/15/2026 1:35:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/17/2026 12:25:00 AM. 50 Economy ticket for $144 per person are available. Travel duration is 32h 50m
FlixBus	37h 0m	9:25 AM	San Diego	Old Town Transit Center	12:25 AM	San Antonio, TX	Bus Station	Economy	$145	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 9/15/2026 9:25:00 AM to Bus Station, San Antonio, TX (USA) arriving at 9/17/2026 12:25:00 AM. 50 Economy ticket for $145 per person are available. Travel duration is 37h 0m
Greyhound US	36h 15m	9:50 AM	San Diego	Old Town Transit Center	12:05 AM	San Antonio, TX	Bus Station	Economy	$153	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 9/15/2026 9:50:00 AM to Bus Station, San Antonio, TX (USA) arriving at 9/17/2026 12:05:00 AM. 50 Economy ticket for $153 per person are available. Travel duration is 36h 15m
Greyhound US	39h 10m	7:45 PM	San Diego	Old Town Transit Center	12:55 PM	San Antonio, TX	Bus Station	Economy	$155	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 9/15/2026 7:45:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/17/2026 12:55:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 39h 10m

Did you know that if you travel from San Diego to San Antonio, TX via Calexico, CA, you can save more than $14? You can find the corresponding connections below.
- Greyhound US
  
  36h 35m
  
  0
  
  9:50 AM
  
  San Diego
  Old Town Transit Center
  
  12:35 PM
  
  Calexico, CA
  Bus Station
  
  0
  
  Economy
  
  $25
  
  A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 9/13/2026 9:50:00 AM to Bus Station, Calexico, CA (USA) arriving at 9/13/2026 12:35:00 PM. 50 Economy ticket for $25 per person are available. Travel duration is 2h 45m
- FlixBus
  
  27h 15m
  
  0
  
  7:10 PM
  
  Calexico, CA
  Bus Station
  
  12:25 AM
  
  San Antonio, TX
  Bus Station
  
  0
  
  Economy
  
  $105
  
  A Bus from FlixBus goes from Bus Station, Calexico, CA (USA) at 9/13/2026 7:10:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/15/2026 12:25:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 27h 15m
Travel time is 1h 45m longer, but you will save $14

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	32h 50m	1:35 PM	San Diego	La Jolla Village	12:25 AM	San Antonio, TX	Bus Station	Economy	$129	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 9/16/2026 1:35:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/18/2026 12:25:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 32h 50m
FlixBus	33h 15m	1:10 PM	San Diego	Seaport Village	12:25 AM	San Antonio, TX	Bus Station	Economy	$130	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 9/16/2026 1:10:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/18/2026 12:25:00 AM. 50 Economy ticket for $130 per person are available. Travel duration is 33h 15m
FlixBus	37h 0m	9:25 AM	San Diego	Old Town Transit Center	12:25 AM	San Antonio, TX	Bus Station	Economy	$131	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 9/16/2026 9:25:00 AM to Bus Station, San Antonio, TX (USA) arriving at 9/18/2026 12:25:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 37h 0m
Greyhound US	36h 15m	9:50 AM	San Diego	Old Town Transit Center	12:05 AM	San Antonio, TX	Bus Station	Economy	$147	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 9/16/2026 9:50:00 AM to Bus Station, San Antonio, TX (USA) arriving at 9/18/2026 12:05:00 AM. 50 Economy ticket for $147 per person are available. Travel duration is 36h 15m
Greyhound US	39h 10m	7:45 PM	San Diego	Old Town Transit Center	12:55 PM	San Antonio, TX	Bus Station	Economy	$147	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 9/16/2026 7:45:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/18/2026 12:55:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 39h 10m

Best Price Offer: The price for the cheapest bus from San Diego to San Antonio, TX is $122 on 10/2/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between San Diego and San Antonio, TX

See here how frequent the connections between San Diego and San Antonio, TX are, during different times and days of the week.

Sunday is the busiest day, with more than 9 daily buses from San Diego to San Antonio, TX. Thursday has instead the fewest connections, with only 2 daily coaches between San Diego and San Antonio, TX.

The busiest time of the day is the Morning, with 14 buses from San Diego to San Antonio, TX, while Evening sees the fewest connections between San Diego and San Antonio, TX, with 8 offers.

Facts about the bus from San Diego to San Antonio, TX

Compare all providers like FlixBus and Greyhound US that travel 5 times every day by bus from San Diego to San Antonio, TX in one click! Book your bus ticket from San Diego to San Antonio, TX starting from $122!

Cheapest Bus	$122
Fastest Bus	34h 50m
Earliest Bus	1:10 PM
Latest Bus	7:45 PM
Daily Bus Routes	5 Ø
Distance	1,126.5 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from San Diego to San Antonio, TX

Every day, 5 buses from 2 bus companies leave San Diego for San Antonio, TX: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/10/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 09/06

Monday 09/07

Tuesday 09/08

Wednesday 09/09

Thursday 09/10

$152

Friday 09/11

$154

Saturday 09/12

Sunday 09/13

$129

Monday 09/14

$150

Tuesday 09/15

$144

Wednesday 09/16

$160

Thursday 09/17

$150

Friday 09/18

Saturday 09/19

$146

Sunday 09/20

$156

Monday 09/21

$147

Tuesday 09/22

$131

Wednesday 09/23

$130

Thursday 09/24

Friday 09/25

$126

Saturday 09/26

$126

Sunday 09/27

Monday 09/28

$147

Tuesday 09/29

Wednesday 09/30

$156

Thursday 10/01

Friday 10/02

$122

Saturday 10/03

The cheapest time to travel from San Diego to San Antonio, TX

See here on which day and which time of the day you can find the cheapest bus ticket from San Diego to San Antonio, TX, for the next 30 days.

With a price starting from $121, Monday is the cheapest day for a bus from San Diego to San Antonio, TX. Thursday instead is the most expensive day with prices starting from $150.

Afternoon is the cheapest day time for bus tickets from San Diego to San Antonio, TX, with $129. Evening is the most expensive time of the day with prices starting from $142.

How to save money travelling from San Diego to San Antonio, TX

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Diego to San Antonio, TX in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Diego to San Antonio, TX, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Diego to San Antonio, TX are also emptier.

Beloved bus companies from San Diego to San Antonio, TX

These are the most booked bus companies between San Diego to San Antonio, TX from our users.

FlixBus from San Diego to San Antonio, TX

Here you will find the key facts about the FlixBus bus route San Diego to San Antonio, TX:

Cheapest Price	$129
Fastest Bus	34h 50m
Earliest Bus	1:10 PM
Last Bus	1:35 PM
Daily Connections	3 Ø
Found on	8/17/2026

Greyhound US from San Diego to San Antonio, TX

Here you will find the key facts about the Greyhound US bus route San Diego to San Antonio, TX:

Cheapest Price	$136
Fastest Bus	38h 5m
Earliest Bus	7:45 PM
Last Bus	7:45 PM
Daily Connections	2 Ø
Found on	8/17/2026

All bus stations and stops in San Diego and San Antonio, TX

In the map below, you can see where to find all bus stations in San Diego and San Antonio, TX.

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Santa Fe Depot

Kettner Blvd 1050

Seaport Village

W Harbor Dr 789

Downtown

Bus Station

N St Mary's St 500

San Antonio

Pearl District

Avenue A 699-599

Commerce & Bowie Bus Stop

W. Southcross & Buffalo Bus Stop

Service and Comfort on the bus from San Diego to San Antonio, TX

Want to know which seat classes are available on the buses from San Diego to San Antonio, TX? Or which bus companies serve the route San Diego to San Antonio, TX? Below you will find answers to your questions.

FAQs about the San Diego to San Antonio, TX bus

How much does a San Diego San Antonio, TX bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $122 and takes 34h 50m to reach San Antonio, TX. Compare offers to save money!

How much could I save by comparing buses from San Diego to San Antonio, TX?

This route is offered by 2 companies with a range of ticket prices between $122 and $179. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Antonio, TX.

On average, how many connections are available from San Diego to San Antonio, TX each day?

Every day, the San Diego to San Antonio, TX bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Diego to San Antonio, TX take?

The fastest bus from San Diego to San Antonio, TX is offered by FlixBus and takes 34h 50m. Bus tickets for this connection cost $158. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Diego to San Antonio, TX?

The earliest bus arriving in San Antonio, TX from San Diego starts at 1:10 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Diego to San Antonio, TX?

The latest bus trip departing from San Diego for San Antonio, TX starts at 7:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Diego San Antonio, TX route?

When traveling by bus from San Diego to San Antonio, TX, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Diego and San Antonio, TX?

You can check all the direct connections between San Diego and San Antonio, TX by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the San Diego to San Antonio, TX bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Diego San Antonio, TX bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Diego San Antonio, TX bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Diego to San Antonio, TX on your planned travel date.

How does CheckMyBus find the best bus deals from San Diego to San Antonio, TX?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 5 daily trips between San Diego and San Antonio, TX. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Diego to San Antonio, TX?

Prices and availability for 5 trips between San Diego and San Antonio, TX change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Diego to San Antonio, TX

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Diego and to San Antonio, TX

Here’s an overview of the most popular bus routes to San Diego and to San Antonio, TX. Simply click on the connection of your choice, and you will find all the details about your bus route!