Bus San Antonio, TX to St. Louis, MO

Compare all timetables for the bus from San Antonio, TX to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from San Antonio, TX to St. Louis, MO from various bus operators like FlixBus, Greyhound US or Greyhound Lines Mexico for the next days.

today

$106

tomorrow

$103

Tuesday

$124

Wednesday

Thursday

$103

Friday

Saturday

$130

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	24h 50m	9:55 PM	San Antonio, TX	Bus Station	10:45 PM	St. Louis, MO	Gateway Station	Economy	$106	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 7/26/2026 9:55:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/27/2026 10:45:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 24h 50m
Greyhound US	21h 15m	1:30 AM	San Antonio, TX	Bus Station	10:45 PM	St. Louis, MO	Gateway Station	Economy	$107	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 7/26/2026 1:30:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/26/2026 10:45:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 21h 15m
FlixBus	23h 40m	7:30 AM	San Antonio, TX	Bus Station	7:10 AM	St. Louis, MO	Gateway Station	Economy	$108	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 7/26/2026 7:30:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/27/2026 7:10:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 23h 40m
FlixBus	23h 25m	7:45 AM	San Antonio, TX	Pearl District	7:10 AM	St. Louis, MO	Gateway Station	Economy	$108	A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 7/26/2026 7:45:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/27/2026 7:10:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 23h 25m
Greyhound US	24h 20m	12:35 PM	San Antonio, TX	Bus Station	12:55 PM	St. Louis, MO	Gateway Station	Economy	$111	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 7/26/2026 12:35:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/27/2026 12:55:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 24h 20m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	21h 15m	1:30 AM	San Antonio, TX	Bus Station	10:45 PM	St. Louis, MO	Gateway Station	Economy	$103	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 7/27/2026 1:30:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/27/2026 10:45:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 21h 15m
FlixBus	24h 50m	9:55 PM	San Antonio, TX	Bus Station	10:45 PM	St. Louis, MO	Gateway Station	Economy	$104	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 7/27/2026 9:55:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/28/2026 10:45:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 24h 50m
FlixBus	23h 40m	7:30 AM	San Antonio, TX	Bus Station	7:10 AM	St. Louis, MO	Gateway Station	Economy	$110	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 7/27/2026 7:30:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/28/2026 7:10:00 AM. 50 Economy ticket for $110 per person are available. Travel duration is 23h 40m
FlixBus	23h 25m	7:45 AM	San Antonio, TX	Pearl District	7:10 AM	St. Louis, MO	Gateway Station	Economy	$110	A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 7/27/2026 7:45:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/28/2026 7:10:00 AM. 50 Economy ticket for $110 per person are available. Travel duration is 23h 25m
Greyhound US	24h 20m	12:35 PM	San Antonio, TX	Bus Station	12:55 PM	St. Louis, MO	Gateway Station	Economy	$123	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 7/27/2026 12:35:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/28/2026 12:55:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 24h 20m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	24h 50m	9:55 PM	San Antonio, TX	Bus Station	10:45 PM	St. Louis, MO	Gateway Station	Economy	$124	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 7/28/2026 9:55:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/29/2026 10:45:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 24h 50m
Greyhound US	21h 15m	1:30 AM	San Antonio, TX	Bus Station	10:45 PM	St. Louis, MO	Gateway Station	Economy	$128	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 7/28/2026 1:30:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/28/2026 10:45:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 21h 15m
Greyhound US	24h 20m	12:35 PM	San Antonio, TX	Bus Station	12:55 PM	St. Louis, MO	Gateway Station	Economy	$136	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 7/28/2026 12:35:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/29/2026 12:55:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 24h 20m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	21h 15m	1:30 AM	San Antonio, TX	Bus Station	10:45 PM	St. Louis, MO	Gateway Station	Economy	$103	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 7/30/2026 1:30:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/30/2026 10:45:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 21h 15m
Greyhound US	24h 20m	12:35 PM	San Antonio, TX	Bus Station	12:55 PM	St. Louis, MO	Gateway Station	Economy	$103	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 7/30/2026 12:35:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/31/2026 12:55:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 24h 20m
FlixBus	23h 40m	7:30 AM	San Antonio, TX	Bus Station	7:10 AM	St. Louis, MO	Gateway Station	Economy	$117	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 7/30/2026 7:30:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/31/2026 7:10:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 23h 40m
FlixBus	23h 25m	7:45 AM	San Antonio, TX	Pearl District	7:10 AM	St. Louis, MO	Gateway Station	Economy	$117	A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 7/30/2026 7:45:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/31/2026 7:10:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 23h 25m
Valley Transit	25h 45m	9:00 PM	San Antonio, TX	Bus Station	10:45 PM	St. Louis, MO	Gateway Station	Economy	$118	A Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 7/30/2026 9:00:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/31/2026 10:45:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 25h 45m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	24h 20m	12:35 PM	San Antonio, TX	Bus Station	12:55 PM	St. Louis, MO	Gateway Station	Economy	$130	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 8/1/2026 12:35:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/2/2026 12:55:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 24h 20m
FlixBus	24h 50m	9:55 PM	San Antonio, TX	Bus Station	10:45 PM	St. Louis, MO	Gateway Station	Economy	$135	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 8/1/2026 9:55:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/2/2026 10:45:00 PM. 50 Economy ticket for $135 per person are available. Travel duration is 24h 50m
FlixBus	23h 40m	7:30 AM	San Antonio, TX	Bus Station	7:10 AM	St. Louis, MO	Gateway Station	Economy	$139	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 8/1/2026 7:30:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 8/2/2026 7:10:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 23h 40m
FlixBus	23h 25m	7:45 AM	San Antonio, TX	Pearl District	7:10 AM	St. Louis, MO	Gateway Station	Economy	$139	A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 8/1/2026 7:45:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 8/2/2026 7:10:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 23h 25m
Greyhound US	21h 15m	1:30 AM	San Antonio, TX	Bus Station	10:45 PM	St. Louis, MO	Gateway Station	Economy	$147	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 8/1/2026 1:30:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 8/1/2026 10:45:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 21h 15m

Did you know that if you travel from San Antonio, TX to St. Louis, MO via Austin, you can save more than $13? You can find the corresponding connections below.
- FlixBus
  
  28h 50m
  
  0
  
  5:55 PM
  
  San Antonio, TX
  Pearl District
  
  8:10 PM
  
  Austin
  RedCoach Stop
  
  0
  
  Economy
  
  $12
  
  A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 8/2/2026 5:55:00 PM to RedCoach Stop, Austin (USA) arriving at 8/2/2026 8:10:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 2h 15m
- Greyhound US
  
  19h 40m
  
  0
  
  3:05 AM
  
  Austin
  5119 Eastside Bus Plaza
  
  10:45 PM
  
  St. Louis, MO
  Gateway Station
  
  0
  
  Economy
  
  $105
  
  A Bus from Greyhound US goes from 5119 Eastside Bus Plaza, Austin (USA) at 8/3/2026 3:05:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 8/3/2026 10:45:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 19h 40m
Travel time is 7h 35m longer, but you will save $13

Best Price Offer: The price for the cheapest bus from San Antonio, TX to St. Louis, MO is $103 on 7/27/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between San Antonio, TX and St. Louis, MO

See here how frequent the connections between San Antonio, TX and St. Louis, MO are, during different times and days of the week.

Sunday is the busiest day, with more than 10 daily buses from San Antonio, TX to St. Louis, MO. Saturday has instead the fewest connections, with only 5 daily coaches between San Antonio, TX and St. Louis, MO.

The busiest time of the day is the Morning, with 14 buses from San Antonio, TX to St. Louis, MO, while Evening sees the fewest connections between San Antonio, TX and St. Louis, MO, with 8 offers.

Facts about the bus from San Antonio, TX to St. Louis, MO

Compare all providers like FlixBus, Greyhound US and Greyhound Lines Mexico that travel 8 times every day by bus from San Antonio, TX to St. Louis, MO in one click! Book your bus ticket from San Antonio, TX to St. Louis, MO starting from $103!

Cheapest Bus	$103
Fastest Bus	21h 15m
Earliest Bus	1:30 AM
Latest Bus	9:55 PM
Daily Bus Routes	8 Ø
Distance	792.3 miles
Bus Companies	FlixBus, Greyhound US, Greyhound Lines Mexico and Valley Transit

Cheapest bus connections from San Antonio, TX to St. Louis, MO

Every day, 8 buses from 4 bus companies leave San Antonio, TX for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/26/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/26

$106

Monday 07/27

$103

Tuesday 07/28

$128

Wednesday 07/29

Thursday 07/30

$103

Friday 07/31

Saturday 08/01

$130

Sunday 08/02

$117

Monday 08/03

$117

Tuesday 08/04

$113

Wednesday 08/05

Thursday 08/06

$104

Friday 08/07

$113

Saturday 08/08

$120

Sunday 08/09

Monday 08/10

$109

Tuesday 08/11

$116

Wednesday 08/12

$108

Thursday 08/13

$106

Friday 08/14

$113

Saturday 08/15

$113

Sunday 08/16

$116

Monday 08/17

$131

Tuesday 08/18

$120

Wednesday 08/19

$112

Thursday 08/20

$116

Friday 08/21

$128

Saturday 08/22

The cheapest time to travel from San Antonio, TX to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from San Antonio, TX to St. Louis, MO, for the next 30 days.

With a price starting from $103, Monday is the cheapest day for a bus from San Antonio, TX to St. Louis, MO. Tuesday instead is the most expensive day with prices starting from $113.

Afternoon is the cheapest day time for bus tickets from San Antonio, TX to St. Louis, MO, with $103. Morning is the most expensive time of the day with prices starting from $108.

How to save money travelling from San Antonio, TX to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Antonio, TX to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Antonio, TX to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Antonio, TX to St. Louis, MO are also emptier.

All bus stations and stops in San Antonio, TX and St. Louis, MO

In the map below, you can see where to find all bus stations in San Antonio, TX and St. Louis, MO.

Bus Station

N St Mary's St 500

San Antonio

Pearl District

Avenue A 699-599

Commerce & Bowie Bus Stop

W. Southcross & Buffalo Bus Stop

Gateway Station

S 15th St 430

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Lindbergh @ Hackberry NB Bus Stop

Service and Comfort on the bus from San Antonio, TX to St. Louis, MO

Want to know which seat classes are available on the buses from San Antonio, TX to St. Louis, MO? Or which bus companies serve the route San Antonio, TX to St. Louis, MO? Below you will find answers to your questions.

FAQs about the San Antonio, TX to St. Louis, MO bus

How much does a San Antonio, TX St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $103 and takes 21h 15m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from San Antonio, TX to St. Louis, MO?

This route is offered by 4 companies with a range of ticket prices between $103 and $147. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from San Antonio, TX to St. Louis, MO each day?

Every day, the San Antonio, TX to St. Louis, MO bus route is served by approximately 8 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Antonio, TX to St. Louis, MO take?

The fastest bus from San Antonio, TX to St. Louis, MO is offered by Greyhound Lines Mexico and takes 21h 15m. Bus tickets for this connection cost $111. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Antonio, TX to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from San Antonio, TX starts at 1:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Antonio, TX to St. Louis, MO?

The latest bus trip departing from San Antonio, TX for St. Louis, MO starts at 9:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Antonio, TX St. Louis, MO route?

When traveling by bus from San Antonio, TX to St. Louis, MO, passengers can travel with FlixBus, Greyhound US and Greyhound Lines Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Antonio, TX and St. Louis, MO?

You can check all the direct connections between San Antonio, TX and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound US and Greyhound Lines Mexico.

What can I take with me on the San Antonio, TX to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Antonio, TX St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Antonio, TX St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Antonio, TX to St. Louis, MO on your planned travel date.

How does CheckMyBus find the best bus deals from San Antonio, TX to St. Louis, MO?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 8 daily trips between San Antonio, TX and St. Louis, MO. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Antonio, TX to St. Louis, MO?

Prices and availability for 8 trips between San Antonio, TX and St. Louis, MO change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Antonio, TX to St. Louis, MO

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Antonio, TX and to St. Louis, MO

Here’s an overview of the most popular bus routes to San Antonio, TX and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!