Bus Phoenix, AZ to Florence, SC: Compare prices and save money

Compare all timetables for the bus from Phoenix, AZ to Florence, SC

Here is a selection of the cheapest bus trips from the schedule from Phoenix, AZ to Florence, SC from various bus operators like Greyhound US or FlixBus for the next days.

today

$135

tomorrow

$141

Monday

$134

Tuesday

$145

Wednesday

$155

Thursday

$131

Friday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	50h 50m	7:40 AM	Phoenix, AZ	Bus Station	1:30 PM	Florence, SC	Bus Station	Economy	$135	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/25/2026 7:40:00 AM to Bus Station, Florence, SC (USA) arriving at 7/27/2026 1:30:00 PM. 50 Economy ticket for $135 per person are available. Travel duration is 50h 50m
Greyhound US	55h 25m	10:45 PM	Phoenix, AZ	Bus Station	9:10 AM	Florence, SC	Bus Station	Economy	$135	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/25/2026 10:45:00 PM to Bus Station, Florence, SC (USA) arriving at 7/28/2026 9:10:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 55h 25m
Greyhound US	54h 15m	4:10 AM	Phoenix, AZ	Bus Station	1:25 PM	Florence, SC	Bus Station	Economy	$138	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/25/2026 4:10:00 AM to Bus Station, Florence, SC (USA) arriving at 7/27/2026 1:25:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 54h 15m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	54h 15m	4:10 AM	Phoenix, AZ	Bus Station	1:25 PM	Florence, SC	Bus Station	Economy	$141	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/26/2026 4:10:00 AM to Bus Station, Florence, SC (USA) arriving at 7/28/2026 1:25:00 PM. 50 Economy ticket for $141 per person are available. Travel duration is 54h 15m
Greyhound US	57h 0m	5:45 PM	Phoenix, AZ	Bus Station	5:45 AM	Florence, SC	TA Travel Center	Economy	$149	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/26/2026 5:45:00 PM to TA Travel Center, Florence, SC (USA) arriving at 7/29/2026 5:45:00 AM. 50 Economy ticket for $149 per person are available. Travel duration is 57h 0m
FlixBus	89h 45m	12:25 PM	Phoenix, AZ	44th St/Washington	9:10 AM	Florence, SC	Bus Station	Economy	$150	A Bus from FlixBus goes from 44th St/Washington, Phoenix, AZ (USA) at 7/26/2026 12:25:00 PM to Bus Station, Florence, SC (USA) arriving at 7/30/2026 9:10:00 AM. 50 Economy ticket for $150 per person are available. Travel duration is 89h 45m
Greyhound US	55h 25m	10:45 PM	Phoenix, AZ	Bus Station	9:10 AM	Florence, SC	Bus Station	Economy	$157	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/26/2026 10:45:00 PM to Bus Station, Florence, SC (USA) arriving at 7/29/2026 9:10:00 AM. 50 Economy ticket for $157 per person are available. Travel duration is 55h 25m
FlixBus	86h 20m	12:25 PM	Phoenix, AZ	44th St/Washington	5:45 AM	Florence, SC	TA Travel Center	Economy	$183	A Bus from FlixBus goes from 44th St/Washington, Phoenix, AZ (USA) at 7/26/2026 12:25:00 PM to TA Travel Center, Florence, SC (USA) arriving at 7/30/2026 5:45:00 AM. 50 Economy ticket for $183 per person are available. Travel duration is 86h 20m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	50h 50m	7:40 AM	Phoenix, AZ	Bus Station	1:30 PM	Florence, SC	Bus Station	Economy	$134	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/27/2026 7:40:00 AM to Bus Station, Florence, SC (USA) arriving at 7/29/2026 1:30:00 PM. 50 Economy ticket for $134 per person are available. Travel duration is 50h 50m
Greyhound US	54h 15m	4:10 AM	Phoenix, AZ	Bus Station	1:25 PM	Florence, SC	Bus Station	Economy	$146	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/27/2026 4:10:00 AM to Bus Station, Florence, SC (USA) arriving at 7/29/2026 1:25:00 PM. 50 Economy ticket for $146 per person are available. Travel duration is 54h 15m
Greyhound US	55h 25m	10:45 PM	Phoenix, AZ	Bus Station	9:10 AM	Florence, SC	Bus Station	Economy	$159	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/27/2026 10:45:00 PM to Bus Station, Florence, SC (USA) arriving at 7/30/2026 9:10:00 AM. 50 Economy ticket for $159 per person are available. Travel duration is 55h 25m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	54h 15m	4:10 AM	Phoenix, AZ	Bus Station	1:25 PM	Florence, SC	Bus Station	Economy	$145	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/28/2026 4:10:00 AM to Bus Station, Florence, SC (USA) arriving at 7/30/2026 1:25:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 54h 15m
Greyhound US	50h 50m	7:40 AM	Phoenix, AZ	Bus Station	1:30 PM	Florence, SC	Bus Station	Economy	$161	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/28/2026 7:40:00 AM to Bus Station, Florence, SC (USA) arriving at 7/30/2026 1:30:00 PM. 50 Economy ticket for $161 per person are available. Travel duration is 50h 50m
Greyhound US	55h 25m	10:45 PM	Phoenix, AZ	Bus Station	9:10 AM	Florence, SC	Bus Station	Economy	$162	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/28/2026 10:45:00 PM to Bus Station, Florence, SC (USA) arriving at 7/31/2026 9:10:00 AM. 50 Economy ticket for $162 per person are available. Travel duration is 55h 25m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	50h 50m	7:40 AM	Phoenix, AZ	Bus Station	1:30 PM	Florence, SC	Bus Station	Economy	$155	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/29/2026 7:40:00 AM to Bus Station, Florence, SC (USA) arriving at 7/31/2026 1:30:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 50h 50m
Greyhound US	55h 25m	10:45 PM	Phoenix, AZ	Bus Station	9:10 AM	Florence, SC	Bus Station	Economy	$156	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/29/2026 10:45:00 PM to Bus Station, Florence, SC (USA) arriving at 8/1/2026 9:10:00 AM. 50 Economy ticket for $156 per person are available. Travel duration is 55h 25m
Greyhound US	61h 45m	7:20 AM	Phoenix, AZ	44th St/Washington	12:05 AM	Florence, SC	TA Travel Center	Economy	$156	A Bus from Greyhound US goes from 44th St/Washington, Phoenix, AZ (USA) at 7/29/2026 7:20:00 AM to TA Travel Center, Florence, SC (USA) arriving at 8/1/2026 12:05:00 AM. 50 Economy ticket for $156 per person are available. Travel duration is 61h 45m
FlixBus	80h 40m	12:25 PM	Phoenix, AZ	44th St/Washington	12:05 AM	Florence, SC	TA Travel Center	Economy	$173	A Bus from FlixBus goes from 44th St/Washington, Phoenix, AZ (USA) at 7/29/2026 12:25:00 PM to TA Travel Center, Florence, SC (USA) arriving at 8/2/2026 12:05:00 AM. 50 Economy ticket for $173 per person are available. Travel duration is 80h 40m
FlixBus	89h 45m	12:25 PM	Phoenix, AZ	44th St/Washington	9:10 AM	Florence, SC	Bus Station	Economy	$173	A Bus from FlixBus goes from 44th St/Washington, Phoenix, AZ (USA) at 7/29/2026 12:25:00 PM to Bus Station, Florence, SC (USA) arriving at 8/2/2026 9:10:00 AM. 50 Economy ticket for $173 per person are available. Travel duration is 89h 45m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	54h 15m	4:10 AM	Phoenix, AZ	Bus Station	1:25 PM	Florence, SC	Bus Station	Economy	$131	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/30/2026 4:10:00 AM to Bus Station, Florence, SC (USA) arriving at 8/1/2026 1:25:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 54h 15m
Greyhound US	50h 50m	7:40 AM	Phoenix, AZ	Bus Station	1:30 PM	Florence, SC	Bus Station	Economy	$148	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/30/2026 7:40:00 AM to Bus Station, Florence, SC (USA) arriving at 8/1/2026 1:30:00 PM. 50 Economy ticket for $148 per person are available. Travel duration is 50h 50m
Greyhound US	55h 25m	10:45 PM	Phoenix, AZ	Bus Station	9:10 AM	Florence, SC	Bus Station	Economy	$161	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/30/2026 10:45:00 PM to Bus Station, Florence, SC (USA) arriving at 8/2/2026 9:10:00 AM. 50 Economy ticket for $161 per person are available. Travel duration is 55h 25m

Best Price Offer: The price for the cheapest bus from Phoenix, AZ to Florence, SC is $115 on 7/19/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Phoenix, AZ and Florence, SC

See here how frequent the connections between Phoenix, AZ and Florence, SC are, during different times and days of the week.

Sunday is the busiest day, with more than 8 daily buses from Phoenix, AZ to Florence, SC. Monday has instead the fewest connections, with only 3 daily coaches between Phoenix, AZ and Florence, SC.

The busiest time of the day is the Morning, with 10 buses from Phoenix, AZ to Florence, SC, while Afternoon sees the fewest connections between Phoenix, AZ and Florence, SC, with 6 offers.

Facts about the bus from Phoenix, AZ to Florence, SC

Compare all providers like Greyhound US and FlixBus that travel 4 times every day by bus from Phoenix, AZ to Florence, SC in one click! Book your bus ticket from Phoenix, AZ to Florence, SC starting from $115!

Cheapest Bus	$115
Fastest Bus	53h 50m
Earliest Bus	4:10 AM
Latest Bus	10:45 PM
Daily Bus Routes	4 Ø
Distance	1,848.2 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Phoenix, AZ to Florence, SC

Every day, 4 buses from 2 bus companies leave Phoenix, AZ for Florence, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/25/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/19

Monday 07/20

Tuesday 07/21

Wednesday 07/22

Thursday 07/23

Friday 07/24

Saturday 07/25

$135

Sunday 07/26

$141

Monday 07/27

$134

Tuesday 07/28

$145

Wednesday 07/29

$155

Thursday 07/30

$131

Friday 07/31

$182

Saturday 08/01

$169

Sunday 08/02

$169

Monday 08/03

$153

Tuesday 08/04

$162

Wednesday 08/05

$151

Thursday 08/06

Friday 08/07

$161

Saturday 08/08

Sunday 08/09

$162

Monday 08/10

$165

Tuesday 08/11

$216

Wednesday 08/12

$198

Thursday 08/13

Friday 08/14

$148

Saturday 08/15

The cheapest time to travel from Phoenix, AZ to Florence, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Phoenix, AZ to Florence, SC, for the next 30 days.

With a price starting from $131, Thursday is the cheapest day for a bus from Phoenix, AZ to Florence, SC. Wednesday instead is the most expensive day with prices starting from $151.

Night is the cheapest day time for bus tickets from Phoenix, AZ to Florence, SC, with $131. Afternoon is the most expensive time of the day with prices starting from $149.

How to save money travelling from Phoenix, AZ to Florence, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Phoenix, AZ to Florence, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Phoenix, AZ to Florence, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Phoenix, AZ to Florence, SC are also emptier.

Beloved bus companies from Phoenix, AZ to Florence, SC

These are the most booked bus companies between Phoenix, AZ to Florence, SC from our users.

Greyhound US from Phoenix, AZ to Florence, SC

Here you will find the key facts about the Greyhound US bus route Phoenix, AZ to Florence, SC:

Cheapest Price	$131
Fastest Bus	53h 50m
Earliest Bus	4:10 AM
Last Bus	10:45 PM
Daily Connections	4 Ø
Found on	6/29/2026

All bus stations and stops in Phoenix, AZ and Florence, SC

In the map below, you can see where to find all bus stations in Phoenix, AZ and Florence, SC.

24th St & Jefferson St Station

24th St & Jefferson St

27th Av & McDowell Rd Bus Stop

N 27th Ave 1614

Bus Station

E Buckeye Rd 2115

44th St/Washington

Downtown

S 1st St 401S

Bus Station

S Irby St 611

TA Travel Center

W Lucas St 2301

Exxon Gas Station

W Lucas Street 1901

McDonalds

W. Lucas St. 1908

Shell Gas Station

W Lucas Street 1832

Service and Comfort on the bus from Phoenix, AZ to Florence, SC

Want to know which seat classes are available on the buses from Phoenix, AZ to Florence, SC? Or which bus companies serve the route Phoenix, AZ to Florence, SC? Below you will find answers to your questions.

FAQs about the Phoenix, AZ to Florence, SC bus

How much does a Phoenix, AZ Florence, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $115 and takes 57h 15m to reach Florence, SC. Compare offers to save money!

How much could I save by comparing buses from Phoenix, AZ to Florence, SC?

This route is offered by 2 companies with a range of ticket prices between $115 and $183. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Florence, SC.

On average, how many connections are available from Phoenix, AZ to Florence, SC each day?

Every day, the Phoenix, AZ to Florence, SC bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Phoenix, AZ to Florence, SC take?

The fastest bus from Phoenix, AZ to Florence, SC is offered by Greyhound US and takes 53h 50m. Bus tickets for this connection cost $135. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Phoenix, AZ to Florence, SC?

The earliest bus arriving in Florence, SC from Phoenix, AZ starts at 4:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Phoenix, AZ to Florence, SC?

The latest bus trip departing from Phoenix, AZ for Florence, SC starts at 10:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Phoenix, AZ Florence, SC route?

When traveling by bus from Phoenix, AZ to Florence, SC, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Phoenix, AZ and Florence, SC?

You can check all the direct connections between Phoenix, AZ and Florence, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Phoenix, AZ to Florence, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Phoenix, AZ Florence, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Phoenix, AZ Florence, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Phoenix, AZ to Florence, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Phoenix, AZ to Florence, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 4 daily trips between Phoenix, AZ and Florence, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Phoenix, AZ to Florence, SC?

Prices and availability for 4 trips between Phoenix, AZ and Florence, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Phoenix, AZ to Florence, SC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Phoenix, AZ and to Florence, SC

Here’s an overview of the most popular bus routes to Phoenix, AZ and to Florence, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!