Bus Fredericksburg, VA to Florence, SC: Compare prices and save money

Compare all timetables for the bus from Fredericksburg, VA to Florence, SC

Here is a selection of the cheapest bus trips from the schedule from Fredericksburg, VA to Florence, SC from various bus operators like Greyhound US for the next days.

today

tomorrow

Thursday

Friday

Saturday

$75

Sunday

Monday

Cheapest bus trips Saturday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	20h 50m	8:55 AM	Fredericksburg, VA	Greyhound Bus Station	5:45 AM	Florence, SC	TA Travel Center		Economy	$75	A Bus from Greyhound US goes from Greyhound Bus Station, Fredericksburg, VA (USA) at 9/12/2026 8:55:00 AM to TA Travel Center, Florence, SC (USA) arriving at 9/13/2026 5:45:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 20h 50m

Did you know that if you travel from Fredericksburg, VA to Florence, SC via Richmond, VA, you can save more than $13? You can find the corresponding connections below.
- Greyhound US
  
  19h 20m
  
  0
  
  10:25 AM
  
  Fredericksburg, VA
  Greyhound Bus Station
  
  11:30 AM
  
  Richmond, VA
  Main Street Station
  
  0
  
  Economy
  
  $12
  
  A Bus from Greyhound US goes from Greyhound Bus Station, Fredericksburg, VA (USA) at 9/9/2026 10:25:00 AM to Main Street Station, Richmond, VA (USA) arriving at 9/9/2026 11:30:00 AM. 50 Economy ticket for $12 per person are available. Travel duration is 1h 5m
- FlixBus
  
  6h 0m
  
  0
  
  11:45 PM
  
  Richmond, VA
  Main Street Station
  
  5:45 AM
  
  Florence, SC
  TA Travel Center
  
  0
  
  Economy
  
  $50
  
  A Bus from FlixBus goes from Main Street Station, Richmond, VA (USA) at 9/9/2026 11:45:00 PM to TA Travel Center, Florence, SC (USA) arriving at 9/10/2026 5:45:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 6h 0m
Travel Time is 1h 30m shorter, and you will save $13

Best Price Offer: The price for the cheapest bus from Fredericksburg, VA to Florence, SC is $65 on 9/17/2026. Flexible travelers save on ticket prices.

Facts about the bus from Fredericksburg, VA to Florence, SC

Compare all providers like Greyhound US that travel 1 times every day by bus from Fredericksburg, VA to Florence, SC in one click! Book your bus ticket from Fredericksburg, VA to Florence, SC starting from $65!

Cheapest Bus	$65
Fastest Bus	20h 50m
Earliest Bus	8:55 AM
Latest Bus	8:55 AM
Daily Bus Routes	1 Ø
Distance	311.5 miles
Bus Companies	Greyhound US

Cheapest bus connections from Fredericksburg, VA to Florence, SC

Every day, 1 buses from 1 bus companies leave Fredericksburg, VA for Florence, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/08/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 09/06

Monday 09/07

Tuesday 09/08

$66

Wednesday 09/09

Thursday 09/10

Friday 09/11

Saturday 09/12

$72

Sunday 09/13

Monday 09/14

Tuesday 09/15

Wednesday 09/16

Thursday 09/17

$65

Friday 09/18

$86

Saturday 09/19

$68

Sunday 09/20

Monday 09/21

Tuesday 09/22

Wednesday 09/23

$65

Thursday 09/24

Friday 09/25

Saturday 09/26

Sunday 09/27

Monday 09/28

Tuesday 09/29

Wednesday 09/30

Thursday 10/01

Friday 10/02

Saturday 10/03

How to save money travelling from Fredericksburg, VA to Florence, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Fredericksburg, VA to Florence, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Fredericksburg, VA to Florence, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Fredericksburg, VA to Florence, SC are also emptier.

All bus stations and stops in Fredericksburg, VA and Florence, SC

In the map below, you can see where to find all bus stations in Fredericksburg, VA and Florence, SC.

Bus Stop

Commuter Lot

Warrenton Rd 627

Cowboy Jack's

Exit 130A, Plank Rd (Across the street of Wawa Gas Station in the Smiles Center next to Cowboys Jack) 2312

Greyhound Bus Station

Jefferson Davis Hwy Srv Rd 1400

NO.1 Bus

Gateway Boulevard 1075

Bus Station

S Irby St 611

Exxon Gas Station

W Lucas Street 1901

McDonalds

W. Lucas St. 1908

Shell Gas Station

W Lucas Street 1832

South Carolina Federal Gas Station

Service and Comfort on the bus from Fredericksburg, VA to Florence, SC

Want to know which seat classes are available on the buses from Fredericksburg, VA to Florence, SC? Or which bus companies serve the route Fredericksburg, VA to Florence, SC? Below you will find answers to your questions.

FAQs about the Fredericksburg, VA to Florence, SC bus

How much does a Fredericksburg, VA Florence, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $65 and takes 20h 50m to reach Florence, SC. Compare offers to save money!

How much could I save by comparing buses from Fredericksburg, VA to Florence, SC?

This route is offered by 1 companies with a range of ticket prices between $65 and $75. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Florence, SC.

On average, how many connections are available from Fredericksburg, VA to Florence, SC each day?

Every day, the Fredericksburg, VA to Florence, SC bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Fredericksburg, VA to Florence, SC take?

The fastest bus from Fredericksburg, VA to Florence, SC is offered by Greyhound US and takes 20h 50m. Bus tickets for this connection cost $75. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Fredericksburg, VA to Florence, SC?

The earliest bus arriving in Florence, SC from Fredericksburg, VA starts at 8:55 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Fredericksburg, VA to Florence, SC?

The latest bus trip departing from Fredericksburg, VA for Florence, SC starts at 8:55 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Fredericksburg, VA Florence, SC route?

When traveling by bus from Fredericksburg, VA to Florence, SC, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Fredericksburg, VA and Florence, SC?

You can check all the direct connections between Fredericksburg, VA and Florence, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Fredericksburg, VA to Florence, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Fredericksburg, VA Florence, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Fredericksburg, VA Florence, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Fredericksburg, VA to Florence, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Fredericksburg, VA to Florence, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 1 daily trips between Fredericksburg, VA and Florence, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Fredericksburg, VA to Florence, SC?

Prices and availability for 1 trips between Fredericksburg, VA and Florence, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Fredericksburg, VA to Florence, SC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Fredericksburg, VA and to Florence, SC

Here’s an overview of the most popular bus routes to Fredericksburg, VA and to Florence, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!