Compare all timetables for the bus from Messina to Milan
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 19h 30m | 11:20 PM | Messina | Piazza della Repubblica | 6:50 PM | Milan | San Donato Bus Station | Economy | $39 |
A Bus from Itabus goes from Piazza della Repubblica, Messina (Italy) at 7/24/2026 11:20:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/25/2026 6:50:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 19h 30m
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| FlixBus | 17h 30m | 8:15 PM | Messina | Piazza della Repubblica | 1:45 PM | Milan | Lampugnano Bus Station | Economy | $49 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/24/2026 8:15:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/25/2026 1:45:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 17h 30m
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| Itabus | 19h 20m | 10:20 AM | Messina | Piazza della Repubblica | 5:40 AM | Milan | Lampugnano Bus Station | Economy | $65 |
A Bus from Itabus goes from Piazza della Repubblica, Messina (Italy) at 7/24/2026 10:20:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/25/2026 5:40:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 19h 20m
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| Itabus | 19h 5m | 9:35 PM | Messina | Central Station | 4:40 PM | Milan | Lampugnano Bus Station | Premium Economy | $74 |
A Bus from Itabus goes from Central Station, Messina (Italy) at 7/24/2026 9:35:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/25/2026 4:40:00 PM. 50 Premium Economy ticket for $74 per person are available. Travel duration is 19h 5m
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| FlixBus | 19h 0m | 10:55 AM | Messina | Piazza della Repubblica | 5:55 AM | Milan | Lampugnano Bus Station | Economy | $75 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/24/2026 10:55:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/25/2026 5:55:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 19h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 19h 30m | 11:20 PM | Messina | Central Station | 6:50 PM | Milan | San Donato Bus Station | Premium Economy | $41 |
A Bus from Itabus goes from Central Station, Messina (Italy) at 7/25/2026 11:20:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/26/2026 6:50:00 PM. 50 Premium Economy ticket for $41 per person are available. Travel duration is 19h 30m
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| FlixBus | 17h 30m | 8:15 PM | Messina | Piazza della Repubblica | 1:45 PM | Milan | Lampugnano Bus Station | Economy | $49 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/25/2026 8:15:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/26/2026 1:45:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 17h 30m
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| FlixBus | 18h 20m | 10:55 AM | Messina | Piazza della Repubblica | 5:15 AM | Milan | San Donato Bus Station | Economy | $54 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/25/2026 10:55:00 AM to San Donato Bus Station, Milan (Italy) arriving at 7/26/2026 5:15:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 18h 20m
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| FlixBus | 19h 0m | 10:55 AM | Messina | Piazza della Repubblica | 5:55 AM | Milan | Lampugnano Bus Station | Economy | $54 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/25/2026 10:55:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/26/2026 5:55:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 19h 0m
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| Itabus | 19h 20m | 10:20 AM | Messina | Piazza della Repubblica | 5:40 AM | Milan | Lampugnano Bus Station | Economy | $65 |
A Bus from Itabus goes from Piazza della Repubblica, Messina (Italy) at 7/25/2026 10:20:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/26/2026 5:40:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 19h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 30m | 8:15 PM | Messina | Piazza della Repubblica | 1:45 PM | Milan | Lampugnano Bus Station | Economy | $43 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/26/2026 8:15:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/27/2026 1:45:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 17h 30m
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| Itabus | 19h 30m | 11:20 PM | Messina | Central Station | 6:50 PM | Milan | San Donato Bus Station | Premium Economy | $48 |
A Bus from Itabus goes from Central Station, Messina (Italy) at 7/26/2026 11:20:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/27/2026 6:50:00 PM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 19h 30m
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| Itabus | 19h 20m | 10:20 AM | Messina | Piazza della Repubblica | 5:40 AM | Milan | Lampugnano Bus Station | Premium Economy | $65 |
A Bus from Itabus goes from Piazza della Repubblica, Messina (Italy) at 7/26/2026 10:20:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/27/2026 5:40:00 AM. 50 Premium Economy ticket for $65 per person are available. Travel duration is 19h 20m
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| FlixBus | 18h 20m | 10:55 AM | Messina | Piazza della Repubblica | 5:15 AM | Milan | San Donato Bus Station | Economy | $71 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/26/2026 10:55:00 AM to San Donato Bus Station, Milan (Italy) arriving at 7/27/2026 5:15:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 18h 20m
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| FlixBus | 19h 0m | 10:55 AM | Messina | Piazza della Repubblica | 5:55 AM | Milan | Lampugnano Bus Station | Economy | $71 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/26/2026 10:55:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/27/2026 5:55:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 19h 0m
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Itabus25h 15m011:50 PMMessinaCentral Station2:20 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Central Station, Messina (Italy) at 7/27/2026 11:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 7/28/2026 2:20:00 PM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 14h 30m
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FlixBus8h 30m04:35 PMRomeTiburtina Bus Station1:05 AMMilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/28/2026 4:35:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/29/2026 1:05:00 AM. 50 Economy ticket for $13 per person are available. Travel duration is 8h 30m
Waiting Time 2h 15m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 30m | 8:15 PM | Messina | Piazza della Repubblica | 1:45 PM | Milan | Lampugnano Bus Station | Economy | $42 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/27/2026 8:15:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/28/2026 1:45:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 17h 30m
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| Itabus | 19h 30m | 11:20 PM | Messina | Central Station | 6:50 PM | Milan | San Donato Bus Station | Premium Economy | $61 |
A Bus from Itabus goes from Central Station, Messina (Italy) at 7/27/2026 11:20:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/28/2026 6:50:00 PM. 50 Premium Economy ticket for $61 per person are available. Travel duration is 19h 30m
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| Itabus | 19h 20m | 10:20 AM | Messina | Piazza della Repubblica | 5:40 AM | Milan | Lampugnano Bus Station | Economy | $65 |
A Bus from Itabus goes from Piazza della Repubblica, Messina (Italy) at 7/27/2026 10:20:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/28/2026 5:40:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 19h 20m
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| FlixBus | 18h 20m | 10:55 AM | Messina | Piazza della Repubblica | 5:15 AM | Milan | San Donato Bus Station | Economy | $69 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/27/2026 10:55:00 AM to San Donato Bus Station, Milan (Italy) arriving at 7/28/2026 5:15:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 18h 20m
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| Autoservizi Salemi | 15h 55m | 9:15 PM | Messina | Piazza della Repubblica | 1:10 PM | Milan | San Donato Bus Station | Economy | $103 |
A Bus from Autoservizi Salemi goes from Piazza della Repubblica, Messina (Italy) at 7/27/2026 9:15:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/28/2026 1:10:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 15h 55m
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FlixBus19h 55m01:30 AMMessinaPiazza della Repubblica11:30 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/29/2026 1:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 7/29/2026 11:30:00 AM. 50 Economy ticket for $25 per person are available. Travel duration is 10h 0m
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Itabus8h 25m01:00 PMRomeTiburtina Bus Station9:25 PMMilanLampugnano Bus Station0EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 7/29/2026 1:00:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/29/2026 9:25:00 PM. 50 Economy ticket for $8 per person are available. Travel duration is 8h 25m
Waiting Time 1h 30m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 30m | 8:15 PM | Messina | Piazza della Repubblica | 1:45 PM | Milan | Lampugnano Bus Station | Economy | $48 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/28/2026 8:15:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/29/2026 1:45:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 17h 30m
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| FlixBus | 18h 20m | 10:55 AM | Messina | Piazza della Repubblica | 5:15 AM | Milan | San Donato Bus Station | Economy | $54 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/28/2026 10:55:00 AM to San Donato Bus Station, Milan (Italy) arriving at 7/29/2026 5:15:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 18h 20m
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| FlixBus | 19h 0m | 10:55 AM | Messina | Piazza della Repubblica | 5:55 AM | Milan | Lampugnano Bus Station | Economy | $54 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/28/2026 10:55:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/29/2026 5:55:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 19h 0m
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| Itabus | 19h 5m | 9:35 PM | Messina | Central Station | 4:40 PM | Milan | Lampugnano Bus Station | Premium Economy | $69 |
A Bus from Itabus goes from Central Station, Messina (Italy) at 7/28/2026 9:35:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/29/2026 4:40:00 PM. 50 Premium Economy ticket for $69 per person are available. Travel duration is 19h 5m
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FlixBus19h 55m01:30 AMMessinaPiazza della Repubblica11:30 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/29/2026 1:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 7/29/2026 11:30:00 AM. 50 Economy ticket for $25 per person are available. Travel duration is 10h 0m
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Itabus8h 25m01:00 PMRomeTiburtina Bus Station9:25 PMMilanLampugnano Bus Station0EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 7/29/2026 1:00:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/29/2026 9:25:00 PM. 50 Economy ticket for $8 per person are available. Travel duration is 8h 25m
Waiting Time 1h 30m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 30m | 8:15 PM | Messina | Piazza della Repubblica | 1:45 PM | Milan | Lampugnano Bus Station | Economy | $47 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/29/2026 8:15:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/30/2026 1:45:00 PM. 50 Economy ticket for $47 per person are available. Travel duration is 17h 30m
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| FlixBus | 19h 0m | 10:55 AM | Messina | Piazza della Repubblica | 5:55 AM | Milan | Lampugnano Bus Station | Economy | $49 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/29/2026 10:55:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/30/2026 5:55:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 19h 0m
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| Itabus | 19h 20m | 10:20 AM | Messina | Central Station | 5:40 AM | Milan | Lampugnano Bus Station | Premium Economy | $57 |
A Bus from Itabus goes from Central Station, Messina (Italy) at 7/29/2026 10:20:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/30/2026 5:40:00 AM. 50 Premium Economy ticket for $57 per person are available. Travel duration is 19h 20m
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| Itabus | 19h 5m | 9:35 PM | Messina | Central Station | 4:40 PM | Milan | Lampugnano Bus Station | Premium Economy | $69 |
A Bus from Itabus goes from Central Station, Messina (Italy) at 7/29/2026 9:35:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/30/2026 4:40:00 PM. 50 Premium Economy ticket for $69 per person are available. Travel duration is 19h 5m
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| Autoservizi Salemi | 15h 55m | 9:15 PM | Messina | Piazza della Repubblica | 1:10 PM | Milan | San Donato Bus Station | Economy | $103 |
A Bus from Autoservizi Salemi goes from Piazza della Repubblica, Messina (Italy) at 7/29/2026 9:15:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/30/2026 1:10:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 15h 55m
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FlixBus20h 10m01:30 AMMessinaPiazza della Repubblica11:30 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/31/2026 1:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 7/31/2026 11:30:00 AM. 50 Economy ticket for $15 per person are available. Travel duration is 10h 0m
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FlixBus9h 30m012:10 PMRomeTiburtina Bus Station9:40 PMMilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/31/2026 12:10:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/31/2026 9:40:00 PM. 50 Economy ticket for $8 per person are available. Travel duration is 9h 30m
Waiting Time 0h 40m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 30m | 8:15 PM | Messina | Piazza della Repubblica | 1:45 PM | Milan | Lampugnano Bus Station | Economy | $46 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/30/2026 8:15:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/31/2026 1:45:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 17h 30m
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| FlixBus | 18h 20m | 10:55 AM | Messina | Piazza della Repubblica | 5:15 AM | Milan | San Donato Bus Station | Economy | $49 |
A Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/30/2026 10:55:00 AM to San Donato Bus Station, Milan (Italy) arriving at 7/31/2026 5:15:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 18h 20m
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| Itabus | 19h 20m | 10:20 AM | Messina | Central Station | 5:40 AM | Milan | Lampugnano Bus Station | Premium Economy | $57 |
A Bus from Itabus goes from Central Station, Messina (Italy) at 7/30/2026 10:20:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/31/2026 5:40:00 AM. 50 Premium Economy ticket for $57 per person are available. Travel duration is 19h 20m
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| Itabus | 19h 5m | 9:35 PM | Messina | Central Station | 4:40 PM | Milan | Lampugnano Bus Station | Premium Economy | $69 |
A Bus from Itabus goes from Central Station, Messina (Italy) at 7/30/2026 9:35:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/31/2026 4:40:00 PM. 50 Premium Economy ticket for $69 per person are available. Travel duration is 19h 5m
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| Autoservizi Salemi | 15h 55m | 9:15 PM | Messina | Piazza della Repubblica | 1:10 PM | Milan | San Donato Bus Station | Economy | $103 |
A Bus from Autoservizi Salemi goes from Piazza della Repubblica, Messina (Italy) at 7/30/2026 9:15:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/31/2026 1:10:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 15h 55m
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FlixBus20h 10m01:30 AMMessinaPiazza della Repubblica11:30 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Piazza della Repubblica, Messina (Italy) at 7/31/2026 1:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 7/31/2026 11:30:00 AM. 50 Economy ticket for $15 per person are available. Travel duration is 10h 0m
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FlixBus9h 30m012:10 PMRomeTiburtina Bus Station9:40 PMMilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 7/31/2026 12:10:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/31/2026 9:40:00 PM. 50 Economy ticket for $8 per person are available. Travel duration is 9h 30m
Waiting Time 0h 40m -
Best Price Offer: The price for the cheapest bus from Messina to Milan is $32 on 8/1/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Messina and Milan
Facts about the bus from Messina to Milan
Compare all providers like Itabus, FlixBus and Autoservizi Salemi that travel 21 times every day by bus from Messina to Milan in one click! Book your bus ticket from Messina to Milan starting from $32!
| Cheapest Bus | $32 |
| Fastest Bus | 15h 55m |
| Earliest Bus | 1:30 AM |
| Latest Bus | 9:35 PM |
| Daily Bus Routes | 21 Ø |
| Distance | 599.7 miles |
| Bus Companies | Itabus, FlixBus and Autoservizi Salemi |
Cheapest bus connections from Messina to Milan
Every day, 21 buses from 3 bus companies leave Messina for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/24/2026 and for the following days.
The cheapest time to travel from Messina to Milan
How to save money travelling from Messina to Milan
Book the ticket from Messina to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Messina to Milan, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Messina to Milan are also emptier.All bus stations and stops in Messina and Milan
In the map below, you can see where to find all bus stations in Messina and Milan.
Compare the bus with other modes of transport
Service and Comfort on the bus from Messina to Milan
FAQs about the Messina to Milan bus
How much does a Messina Milan bus trip cost?
How much could I save by comparing buses from Messina to Milan?
On average, how many connections are available from Messina to Milan each day?
How long does a bus journey from Messina to Milan take?
What time is the first bus from Messina to Milan?
What time is the last bus from Messina to Milan?
Which bus companies operate the Messina Milan route?
Is there a direct bus between Messina and Milan?
What can I take with me on the Messina to Milan bus route?
What equipment is available for the Messina Milan bus route?
How does CheckMyBus find the best bus deals from Messina to Milan?
How does CheckMyBus technology work for trips from Messina to Milan?
Available seat classes which are offered on the bus route Messina to Milan
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
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