Compare all timetables for the bus from Rome to Messina
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 10h 15m | 7:30 PM | Rome | Tiburtina Bus Station | 5:45 AM | Messina | Piazza della Repubblica | Economy | $24 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 10/22/2026 7:30:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 10/23/2026 5:45:00 AM. 50 Economy ticket for $24 per person are available. Travel duration is 10h 15m
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| FlixBus | 10h 55m | 8:55 AM | Rome | Tiburtina Bus Station | 7:50 PM | Messina | Piazza della Repubblica | Economy | $29 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/22/2026 8:55:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 10/22/2026 7:50:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 10h 55m
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| FlixBus | 9h 50m | 1:20 AM | Rome | Tiburtina Bus Station | 11:10 AM | Messina | Piazza della Repubblica | Economy | $30 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/22/2026 1:20:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 10/22/2026 11:10:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 9h 50m
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| Itabus | 14h 25m | 4:25 PM | Rome | Tiburtina Bus Station | 6:50 AM | Messina | Central Station | Premium Economy | $34 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 10/22/2026 4:25:00 PM to Central Station, Messina (Italy) arriving at 10/23/2026 6:50:00 AM. 50 Premium Economy ticket for $34 per person are available. Travel duration is 14h 25m
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| Autoservizi Salemi | 8h 40m | 8:00 PM | Rome | Tiburtina Bus Station | 4:40 AM | Messina | Piazza della Repubblica | Economy | $46 |
A Bus from Autoservizi Salemi goes from Tiburtina Bus Station, Rome (Italy) at 10/22/2026 8:00:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 10/23/2026 4:40:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 8h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Interbus | 1h 25m | 6:05 AM | Rome | Appia/Quarto Miglio | 7:30 AM | Messina | Central Station | Economy | $3 |
A Bus from Interbus goes from Appia/Quarto Miglio, Rome (Italy) at 10/23/2026 6:05:00 AM to Central Station, Messina (Italy) arriving at 10/23/2026 7:30:00 AM. 50 Economy ticket for $3 per person are available. Travel duration is 1h 25m
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| FlixBus | 9h 50m | 1:20 AM | Rome | Tiburtina Bus Station | 11:10 AM | Messina | Piazza della Repubblica | Economy | $27 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/23/2026 1:20:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 10/23/2026 11:10:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 9h 50m
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| Itabus | 14h 25m | 4:25 PM | Rome | Tiburtina Bus Station | 6:50 AM | Messina | Piazza della Repubblica | Economy | $32 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 10/23/2026 4:25:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 10/24/2026 6:50:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 14h 25m
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| Itabus | 10h 15m | 7:30 PM | Rome | Tiburtina Bus Station | 5:45 AM | Messina | Piazza della Repubblica | Economy | $32 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 10/23/2026 7:30:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 10/24/2026 5:45:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 10h 15m
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| FlixBus | 10h 55m | 8:55 AM | Rome | Tiburtina Bus Station | 7:50 PM | Messina | Piazza della Repubblica | Economy | $33 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/23/2026 8:55:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 10/23/2026 7:50:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 10h 55m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 10h 15m | 7:30 PM | Rome | Tiburtina Bus Station | 4:45 AM | Messina | Piazza della Repubblica | Premium Economy | $20 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 10/24/2026 7:30:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 10/25/2026 4:45:00 AM. 50 Premium Economy ticket for $20 per person are available. Travel duration is 10h 15m
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| Itabus | 14h 25m | 4:25 PM | Rome | Tiburtina Bus Station | 5:50 AM | Messina | Central Station | Premium Economy | $26 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 10/24/2026 4:25:00 PM to Central Station, Messina (Italy) arriving at 10/25/2026 5:50:00 AM. 50 Premium Economy ticket for $26 per person are available. Travel duration is 14h 25m
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| FlixBus | 10h 55m | 8:55 AM | Rome | Tiburtina Bus Station | 7:50 PM | Messina | Piazza della Repubblica | Economy | $27 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/24/2026 8:55:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 10/24/2026 7:50:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 10h 55m
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| FlixBus | 9h 50m | 1:20 AM | Rome | Tiburtina Bus Station | 11:10 AM | Messina | Piazza della Repubblica | Economy | $30 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/24/2026 1:20:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 10/24/2026 11:10:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 9h 50m
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| Autoservizi Salemi | 8h 40m | 8:00 PM | Rome | Tiburtina Bus Station | 3:40 AM | Messina | Piazza della Repubblica | Economy | $45 |
A Bus from Autoservizi Salemi goes from Tiburtina Bus Station, Rome (Italy) at 10/24/2026 8:00:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 10/25/2026 3:40:00 AM. 50 Economy ticket for $45 per person are available. Travel duration is 8h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 9h 50m | 1:20 AM | Rome | Tiburtina Bus Station | 10:10 AM | Messina | Piazza della Repubblica | Economy | $20 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/25/2026 1:20:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 10/25/2026 10:10:00 AM. 50 Economy ticket for $20 per person are available. Travel duration is 9h 50m
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| Itabus | 10h 15m | 7:30 PM | Rome | Tiburtina Bus Station | 5:45 AM | Messina | Piazza della Repubblica | Premium Economy | $26 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 10/25/2026 7:30:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 10/26/2026 5:45:00 AM. 50 Premium Economy ticket for $26 per person are available. Travel duration is 10h 15m
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| FlixBus | 10h 55m | 7:55 AM | Rome | Tiburtina Bus Station | 6:50 PM | Messina | Piazza della Repubblica | Economy | $29 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/25/2026 7:55:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 10/25/2026 6:50:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 10h 55m
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| Itabus | 14h 25m | 4:25 PM | Rome | Tiburtina Bus Station | 6:50 AM | Messina | Central Station | Premium Economy | $34 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 10/25/2026 4:25:00 PM to Central Station, Messina (Italy) arriving at 10/26/2026 6:50:00 AM. 50 Premium Economy ticket for $34 per person are available. Travel duration is 14h 25m
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| Autoservizi Salemi | 8h 40m | 8:00 PM | Rome | Tiburtina Bus Station | 4:40 AM | Messina | Piazza della Repubblica | Economy | $44 |
A Bus from Autoservizi Salemi goes from Tiburtina Bus Station, Rome (Italy) at 10/25/2026 8:00:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 10/26/2026 4:40:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 8h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Interbus | 1h 25m | 6:05 AM | Rome | Appia/Quarto Miglio | 7:30 AM | Messina | Central Station | Economy | $3 |
A Bus from Interbus goes from Appia/Quarto Miglio, Rome (Italy) at 10/26/2026 6:05:00 AM to Central Station, Messina (Italy) arriving at 10/26/2026 7:30:00 AM. 50 Economy ticket for $3 per person are available. Travel duration is 1h 25m
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| Itabus | 10h 15m | 7:30 PM | Rome | Tiburtina Bus Station | 5:45 AM | Messina | Central Station | Premium Economy | $26 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 10/26/2026 7:30:00 PM to Central Station, Messina (Italy) arriving at 10/27/2026 5:45:00 AM. 50 Premium Economy ticket for $26 per person are available. Travel duration is 10h 15m
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| FlixBus | 10h 55m | 8:55 AM | Rome | Tiburtina Bus Station | 7:50 PM | Messina | Piazza della Repubblica | Economy | $29 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/26/2026 8:55:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 10/26/2026 7:50:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 10h 55m
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| FlixBus | 9h 50m | 1:20 AM | Rome | Tiburtina Bus Station | 11:10 AM | Messina | Piazza della Repubblica | Economy | $30 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/26/2026 1:20:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 10/26/2026 11:10:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 9h 50m
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| Autoservizi Salemi | 8h 40m | 8:00 PM | Rome | Tiburtina Bus Station | 4:40 AM | Messina | Piazza della Repubblica | Economy | $34 |
A Bus from Autoservizi Salemi goes from Tiburtina Bus Station, Rome (Italy) at 10/26/2026 8:00:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 10/27/2026 4:40:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 8h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Interbus | 1h 25m | 6:05 AM | Rome | Appia/Quarto Miglio | 7:30 AM | Messina | Central Station | Economy | $3 |
A Bus from Interbus goes from Appia/Quarto Miglio, Rome (Italy) at 10/27/2026 6:05:00 AM to Central Station, Messina (Italy) arriving at 10/27/2026 7:30:00 AM. 50 Economy ticket for $3 per person are available. Travel duration is 1h 25m
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| FlixBus | 10h 55m | 8:55 AM | Rome | Tiburtina Bus Station | 7:50 PM | Messina | Piazza della Repubblica | Economy | $15 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/27/2026 8:55:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 10/27/2026 7:50:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 10h 55m
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| FlixBus | 9h 50m | 1:20 AM | Rome | Tiburtina Bus Station | 11:10 AM | Messina | Piazza della Repubblica | Economy | $27 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/27/2026 1:20:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 10/27/2026 11:10:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 9h 50m
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| Itabus | 10h 15m | 7:30 PM | Rome | Tiburtina Bus Station | 5:45 AM | Messina | Piazza della Repubblica | Economy | $31 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 10/27/2026 7:30:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 10/28/2026 5:45:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 10h 15m
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| Autoservizi Salemi | 8h 40m | 8:00 PM | Rome | Tiburtina Bus Station | 4:40 AM | Messina | Piazza della Repubblica | Economy | $34 |
A Bus from Autoservizi Salemi goes from Tiburtina Bus Station, Rome (Italy) at 10/27/2026 8:00:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 10/28/2026 4:40:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 8h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 10h 15m | 7:30 PM | Rome | Tiburtina Bus Station | 5:45 AM | Messina | Central Station | Premium Economy | $20 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 10/28/2026 7:30:00 PM to Central Station, Messina (Italy) arriving at 10/29/2026 5:45:00 AM. 50 Premium Economy ticket for $20 per person are available. Travel duration is 10h 15m
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| FlixBus | 9h 50m | 1:20 AM | Rome | Tiburtina Bus Station | 11:10 AM | Messina | Piazza della Repubblica | Economy | $30 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/28/2026 1:20:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 10/28/2026 11:10:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 9h 50m
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| FlixBus | 10h 55m | 8:55 AM | Rome | Tiburtina Bus Station | 7:50 PM | Messina | Piazza della Repubblica | Economy | $30 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 10/28/2026 8:55:00 AM to Piazza della Repubblica, Messina (Italy) arriving at 10/28/2026 7:50:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 10h 55m
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| Autoservizi Salemi | 8h 40m | 8:00 PM | Rome | Tiburtina Bus Station | 4:40 AM | Messina | Piazza della Repubblica | Economy | $34 |
A Bus from Autoservizi Salemi goes from Tiburtina Bus Station, Rome (Italy) at 10/28/2026 8:00:00 PM to Piazza della Repubblica, Messina (Italy) arriving at 10/29/2026 4:40:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 8h 40m
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Itabus10h 0m07:45 PMRomeTiburtina Bus Station10:25 PMNaplesMetropark Centrale0Premium EconomyA Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 10/28/2026 7:45:00 PM to Metropark Centrale, Naples (Italy) arriving at 10/28/2026 10:25:00 PM. 50 Premium Economy ticket for $6 per person are available. Travel duration is 2h 40m
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Itabus7h 10m010:35 PMNaplesMetropark Centrale5:45 AMMessinaCentral Station0Premium EconomyA Bus from Itabus goes from Metropark Centrale, Naples (Italy) at 10/28/2026 10:35:00 PM to Central Station, Messina (Italy) arriving at 10/29/2026 5:45:00 AM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 7h 10m
Waiting Time 0h 10m -
Best Price Offer: The price for the cheapest bus from Rome to Messina is $3 on 10/23/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Rome and Messina
Facts about the bus from Rome to Messina
Compare all providers like Itabus, FlixBus and Autoservizi Salemi that travel 15 times every day by bus from Rome to Messina in one click! Book your bus ticket from Rome to Messina starting from $3!
| Cheapest Bus | $3 |
| Fastest Bus | 1h 25m |
| Earliest Bus | 1:20 AM |
| Latest Bus | 11:30 PM |
| Daily Bus Routes | 15 Ø |
| Distance | 303.0 miles |
| Bus Companies | Itabus, FlixBus, Autoservizi Salemi and Interbus |
Cheapest bus connections from Rome to Messina
Every day, 15 buses from 4 bus companies leave Rome for Messina: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/22/2026 and for the following days.
The cheapest time to travel from Rome to Messina
How to save money travelling from Rome to Messina
Book the ticket from Rome to Messina in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Messina, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Rome to Messina are also emptier.Beloved bus companies from Rome to Messina
FlixBus from Rome to Messina
Here you will find the key facts about the FlixBus bus route Rome to Messina:
| Cheapest Price | $15 |
| Fastest Bus | 8h 30m |
| Earliest Bus | 1:20 AM |
| Last Bus | 11:30 PM |
| Daily Connections | 5 Ø |
| Found on | 10/21/2026 |
Itabus from Rome to Messina
Here you will find the key facts about the Itabus bus route Rome to Messina:
| Cheapest Price | $20 |
| Fastest Bus | 9h 15m |
| Earliest Bus | 4:25 PM |
| Last Bus | 7:30 PM |
| Daily Connections | 8 Ø |
| Found on | 10/21/2026 |
Latest reviews for bus companies on the route Rome - Messina
All bus stations and stops in Rome and Messina
In the map below, you can see where to find all bus stations in Rome and Messina.
Compare the bus with other modes of transport
Service and Comfort on the bus from Rome to Messina
FAQs about the Rome to Messina bus
How much does a Rome Messina bus trip cost?
How much could I save by comparing buses from Rome to Messina?
On average, how many connections are available from Rome to Messina each day?
How long does a bus journey from Rome to Messina take?
What time is the first bus from Rome to Messina?
What time is the last bus from Rome to Messina?
Which bus companies operate the Rome Messina route?
Is there a direct bus between Rome and Messina?
What can I take with me on the Rome to Messina bus route?
What equipment is available for the Rome Messina bus route?
How does CheckMyBus find the best bus deals from Rome to Messina?
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Available seat classes which are offered on the bus route Rome to Messina
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
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