Bus La Serena to Rancagua - Compare all Companies

Compare all timetables for the bus from La Serena to Rancagua

Here is a selection of the cheapest bus trips from the schedule from La Serena to Rancagua from various bus operators like Turbus or FlixBus for the next days.

today

$27

tomorrow

$32

Friday

$25

Saturday

$32

Sunday

$27

Monday

$22

Tuesday

$22

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	8h 35m	11:50 PM	La Serena	Central Bus Station	8:25 AM	Rancagua	Bus Stop	Economy	$27	A Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 9/9/2026 11:50:00 PM to Bus Stop, Rancagua (Chile) arriving at 9/10/2026 8:25:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 8h 35m
FlixBus	8h 40m	11:50 PM	La Serena	Central Bus Station	8:30 AM	Rancagua	Terminal O'Higgins	Economy	$27	A Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 9/9/2026 11:50:00 PM to Terminal O'Higgins, Rancagua (Chile) arriving at 9/10/2026 8:30:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 8h 40m
Turbus	7h 55m	7:00 PM	La Serena	Avda. Fco de Aguirre Station	2:55 AM	Rancagua	Estación Estado	First Class	$32	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 9/9/2026 7:00:00 PM to Estación Estado, Rancagua (Chile) arriving at 9/10/2026 2:55:00 AM. 50 First Class ticket for $32 per person are available. Travel duration is 7h 55m
Turbus	18h 15m	3:10 PM	La Serena	Avda. Fco de Aguirre Station	9:25 AM	Rancagua	Rodoviario Rancagua	Premium Economy	$48	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 9/9/2026 3:10:00 PM to Rodoviario Rancagua, Rancagua (Chile) arriving at 9/10/2026 9:25:00 AM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 18h 15m
Turbus	18h 0m	6:40 PM	La Serena	Avda. Fco de Aguirre Station	12:40 PM	Rancagua	Rodoviario Rancagua	Premium Economy	$48	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 9/9/2026 6:40:00 PM to Rodoviario Rancagua, Rancagua (Chile) arriving at 9/10/2026 12:40:00 PM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 18h 0m

Did you know that if you travel from La Serena to Rancagua via Coquimbo, you can save more than $-10? You will find the corresponding connections below.
- 12h 15m
  
  La Serena
  
  7 mi
  
  2:30 PM
  
  Coquimbo
  La Cantera Bus Stop
  
  2:45 AM
  
  Rancagua
  Rodoviario Rancagua
  
  0 mi
  
  Premium Economy
  
  $37
  
  A Bus from goes from La Cantera Bus Stop, Coquimbo (Chile) at 9/9/2026 2:30:00 PM to Rodoviario Rancagua, Rancagua (Chile) arriving at 9/10/2026 2:45:00 AM. 50 Premium Economy ticket for $37 per person are available. Travel duration is 12h 15m
Did you know that if you travel from La Serena to Rancagua via Santiago, RM, you can save more than $12? You can find the corresponding connections below.
- Buses Romani
  
  7h 25m
  
  0
  
  12:45 AM
  
  La Serena
  Central Bus Station
  
  7:00 AM
  
  Santiago, RM
  Sur Bus Station
  
  0
  
  Premium Economy
  
  $11
  
  A Bus from Buses Romani goes from Central Bus Station, La Serena (Chile) at 9/11/2026 12:45:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 9/11/2026 7:00:00 AM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 6h 15m
- Andimar
  
  0h 55m
  
  0
  
  7:15 AM
  
  Santiago, RM
  Sur Bus Station
  
  8:10 AM
  
  Rancagua
  Bus Stop
  
  0
  
  Economy
  
  $4
  
  A Bus from Andimar goes from Sur Bus Station, Santiago, RM (Chile) at 9/11/2026 7:15:00 AM to Bus Stop, Rancagua (Chile) arriving at 9/11/2026 8:10:00 AM. 50 Economy ticket for $4 per person are available. Travel duration is 0h 55m
Travel Time is 0h 30m shorter, and you will save $12

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Turbus	7h 55m	7:00 PM	La Serena	Avda. Fco de Aguirre Station	2:55 AM	Rancagua	Estación Estado	First Class	$32	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 9/10/2026 7:00:00 PM to Estación Estado, Rancagua (Chile) arriving at 9/11/2026 2:55:00 AM. 50 First Class ticket for $32 per person are available. Travel duration is 7h 55m
Turbus	18h 5m	1:05 AM	La Serena	Avda. Fco de Aguirre Station	7:10 PM	Rancagua	Rodoviario Rancagua	Premium Economy	$48	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 9/10/2026 1:05:00 AM to Rodoviario Rancagua, Rancagua (Chile) arriving at 9/10/2026 7:10:00 PM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 18h 5m
Turbus	18h 15m	3:10 PM	La Serena	Avda. Fco de Aguirre Station	9:25 AM	Rancagua	Rodoviario Rancagua	Premium Economy	$48	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 9/10/2026 3:10:00 PM to Rodoviario Rancagua, Rancagua (Chile) arriving at 9/11/2026 9:25:00 AM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 18h 15m
Turbus	17h 50m	7:30 PM	La Serena	Avda. Fco de Aguirre Station	1:20 PM	Rancagua	Rodoviario Rancagua	Premium Economy	$48	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 9/10/2026 7:30:00 PM to Rodoviario Rancagua, Rancagua (Chile) arriving at 9/11/2026 1:20:00 PM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 17h 50m
Turbus	19h 10m	5:55 AM	La Serena	Avda. Fco de Aguirre Station	1:05 AM	Rancagua	Rodoviario Rancagua	Premium Economy	$50	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 9/10/2026 5:55:00 AM to Rodoviario Rancagua, Rancagua (Chile) arriving at 9/11/2026 1:05:00 AM. 50 Premium Economy ticket for $50 per person are available. Travel duration is 19h 10m

Did you know that if you travel from La Serena to Rancagua via Coquimbo, you can save more than $11? You will find the corresponding connections below.
- FlixBus
  
  Save more than 34%
  
  8h 15m
  
  La Serena
  
  7 mi
  
  12:10 AM
  
  Coquimbo
  Bus Station
  
  8:25 AM
  
  Rancagua
  Bus Stop
  
  0 mi
  
  Economy
  
  $21
  
  A Bus from FlixBus goes from Bus Station, Coquimbo (Chile) at 9/10/2026 12:10:00 AM to Bus Stop, Rancagua (Chile) arriving at 9/10/2026 8:25:00 AM. 50 Economy ticket for $21 per person are available. Travel duration is 8h 15m
Did you know that if you travel from La Serena to Rancagua via Santiago, RM, you can save more than $17? You can find the corresponding connections below.
- Buses Romani
  
  7h 25m
  
  0
  
  12:45 AM
  
  La Serena
  Central Bus Station
  
  7:00 AM
  
  Santiago, RM
  Sur Bus Station
  
  0
  
  Premium Economy
  
  $11
  
  A Bus from Buses Romani goes from Central Bus Station, La Serena (Chile) at 9/11/2026 12:45:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 9/11/2026 7:00:00 AM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 6h 15m
- Andimar
  
  0h 55m
  
  0
  
  7:15 AM
  
  Santiago, RM
  Sur Bus Station
  
  8:10 AM
  
  Rancagua
  Bus Stop
  
  0
  
  Economy
  
  $4
  
  A Bus from Andimar goes from Sur Bus Station, Santiago, RM (Chile) at 9/11/2026 7:15:00 AM to Bus Stop, Rancagua (Chile) arriving at 9/11/2026 8:10:00 AM. 50 Economy ticket for $4 per person are available. Travel duration is 0h 55m
Travel Time is 0h 30m shorter, and you will save $17

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	8h 26m	11:59 PM	La Serena	Central Bus Station	8:25 AM	Rancagua	Bus Stop	Economy	$25	A Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 9/11/2026 11:59:00 PM to Bus Stop, Rancagua (Chile) arriving at 9/12/2026 8:25:00 AM. 50 Economy ticket for $25 per person are available. Travel duration is 8h 26m
FlixBus	8h 31m	11:59 PM	La Serena	Central Bus Station	8:30 AM	Rancagua	Terminal O'Higgins	Economy	$25	A Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 9/11/2026 11:59:00 PM to Terminal O'Higgins, Rancagua (Chile) arriving at 9/12/2026 8:30:00 AM. 50 Economy ticket for $25 per person are available. Travel duration is 8h 31m
Turbus	11h 10m	1:05 AM	La Serena	Avda. Fco de Aguirre Station	12:15 PM	Rancagua	Rodoviario Rancagua	Premium Economy	$34	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 9/11/2026 1:05:00 AM to Rodoviario Rancagua, Rancagua (Chile) arriving at 9/11/2026 12:15:00 PM. 50 Premium Economy ticket for $34 per person are available. Travel duration is 11h 10m
Turbus	12h 15m	5:55 AM	La Serena	Avda. Fco de Aguirre Station	6:10 PM	Rancagua	Rodoviario Rancagua	Premium Economy	$34	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 9/11/2026 5:55:00 AM to Rodoviario Rancagua, Rancagua (Chile) arriving at 9/11/2026 6:10:00 PM. 50 Premium Economy ticket for $34 per person are available. Travel duration is 12h 15m
Turbus	12h 5m	9:10 AM	La Serena	Avda. Fco de Aguirre Station	9:15 PM	Rancagua	Rodoviario Rancagua	Premium Economy	$34	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 9/11/2026 9:10:00 AM to Rodoviario Rancagua, Rancagua (Chile) arriving at 9/11/2026 9:15:00 PM. 50 Premium Economy ticket for $34 per person are available. Travel duration is 12h 5m

Did you know that if you travel from La Serena to Rancagua via Santiago, RM, you can save more than $10? You can find the corresponding connections below.
- Buses Romani
  
  7h 25m
  
  0
  
  12:45 AM
  
  La Serena
  Central Bus Station
  
  7:00 AM
  
  Santiago, RM
  Sur Bus Station
  
  0
  
  Premium Economy
  
  $11
  
  A Bus from Buses Romani goes from Central Bus Station, La Serena (Chile) at 9/11/2026 12:45:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 9/11/2026 7:00:00 AM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 6h 15m
- Andimar
  
  0h 55m
  
  0
  
  7:15 AM
  
  Santiago, RM
  Sur Bus Station
  
  8:10 AM
  
  Rancagua
  Bus Stop
  
  0
  
  Economy
  
  $4
  
  A Bus from Andimar goes from Sur Bus Station, Santiago, RM (Chile) at 9/11/2026 7:15:00 AM to Bus Stop, Rancagua (Chile) arriving at 9/11/2026 8:10:00 AM. 50 Economy ticket for $4 per person are available. Travel duration is 0h 55m
Travel Time is 1h 1m shorter, and you will save $10

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Turbus	7h 55m	7:00 PM	La Serena	Avda. Fco de Aguirre Station	2:55 AM	Rancagua	Estación Estado	First Class	$32	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 9/12/2026 7:00:00 PM to Estación Estado, Rancagua (Chile) arriving at 9/13/2026 2:55:00 AM. 50 First Class ticket for $32 per person are available. Travel duration is 7h 55m
FlixBus	8h 35m	11:50 PM	La Serena	Central Bus Station	8:25 AM	Rancagua	Bus Stop	Economy	$32	A Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 9/12/2026 11:50:00 PM to Bus Stop, Rancagua (Chile) arriving at 9/13/2026 8:25:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 8h 35m
FlixBus	8h 40m	11:50 PM	La Serena	Central Bus Station	8:30 AM	Rancagua	Terminal O'Higgins	Economy	$32	A Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 9/12/2026 11:50:00 PM to Terminal O'Higgins, Rancagua (Chile) arriving at 9/13/2026 8:30:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 8h 40m
Turbus	11h 10m	1:05 AM	La Serena	Avda. Fco de Aguirre Station	12:15 PM	Rancagua	Rodoviario Rancagua	Premium Economy	$34	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 9/12/2026 1:05:00 AM to Rodoviario Rancagua, Rancagua (Chile) arriving at 9/12/2026 12:15:00 PM. 50 Premium Economy ticket for $34 per person are available. Travel duration is 11h 10m
Turbus	12h 5m	9:10 AM	La Serena	Avda. Fco de Aguirre Station	9:15 PM	Rancagua	Rodoviario Rancagua	Premium Economy	$34	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 9/12/2026 9:10:00 AM to Rodoviario Rancagua, Rancagua (Chile) arriving at 9/12/2026 9:15:00 PM. 50 Premium Economy ticket for $34 per person are available. Travel duration is 12h 5m

Did you know that if you travel from La Serena to Rancagua via Coquimbo, you can save more than $7? You will find the corresponding connections below.
- Save more than 22%
  
  7h 55m
  
  La Serena
  
  7 mi
  
  12:30 AM
  
  Coquimbo
  Bus Station
  
  8:25 AM
  
  Rancagua
  Bus Stop
  
  0 mi
  
  Economy
  
  $25
  
  A Bus from goes from Bus Station, Coquimbo (Chile) at 9/12/2026 12:30:00 AM to Bus Stop, Rancagua (Chile) arriving at 9/12/2026 8:25:00 AM. 50 Economy ticket for $25 per person are available. Travel duration is 7h 55m
Did you know that if you travel from La Serena to Rancagua via Santiago, RM, you can save more than $17? You can find the corresponding connections below.
- Buses Romani
  
  7h 25m
  
  0
  
  12:45 AM
  
  La Serena
  Central Bus Station
  
  7:00 AM
  
  Santiago, RM
  Sur Bus Station
  
  0
  
  Premium Economy
  
  $11
  
  A Bus from Buses Romani goes from Central Bus Station, La Serena (Chile) at 9/11/2026 12:45:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 9/11/2026 7:00:00 AM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 6h 15m
- Andimar
  
  0h 55m
  
  0
  
  7:15 AM
  
  Santiago, RM
  Sur Bus Station
  
  8:10 AM
  
  Rancagua
  Bus Stop
  
  0
  
  Economy
  
  $4
  
  A Bus from Andimar goes from Sur Bus Station, Santiago, RM (Chile) at 9/11/2026 7:15:00 AM to Bus Stop, Rancagua (Chile) arriving at 9/11/2026 8:10:00 AM. 50 Economy ticket for $4 per person are available. Travel duration is 0h 55m
Travel Time is 0h 30m shorter, and you will save $17

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	8h 26m	11:59 PM	La Serena	Central Bus Station	8:25 AM	Rancagua	Bus Stop	Economy	$27	A Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 9/13/2026 11:59:00 PM to Bus Stop, Rancagua (Chile) arriving at 9/14/2026 8:25:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 8h 26m
FlixBus	8h 31m	11:59 PM	La Serena	Central Bus Station	8:30 AM	Rancagua	Terminal O'Higgins	Economy	$27	A Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 9/13/2026 11:59:00 PM to Terminal O'Higgins, Rancagua (Chile) arriving at 9/14/2026 8:30:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 8h 31m
Turbus	7h 55m	7:00 PM	La Serena	Avda. Fco de Aguirre Station	2:55 AM	Rancagua	Estación Estado	First Class	$38	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 9/13/2026 7:00:00 PM to Estación Estado, Rancagua (Chile) arriving at 9/14/2026 2:55:00 AM. 50 First Class ticket for $38 per person are available. Travel duration is 7h 55m
Turbus	18h 5m	1:05 AM	La Serena	Avda. Fco de Aguirre Station	7:10 PM	Rancagua	Rodoviario Rancagua	Premium Economy	$47	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 9/13/2026 1:05:00 AM to Rodoviario Rancagua, Rancagua (Chile) arriving at 9/13/2026 7:10:00 PM. 50 Premium Economy ticket for $47 per person are available. Travel duration is 18h 5m
Turbus	19h 10m	5:55 AM	La Serena	Avda. Fco de Aguirre Station	1:05 AM	Rancagua	Rodoviario Rancagua	Premium Economy	$48	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 9/13/2026 5:55:00 AM to Rodoviario Rancagua, Rancagua (Chile) arriving at 9/14/2026 1:05:00 AM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 19h 10m

Did you know that if you travel from La Serena to Rancagua via Coquimbo, you can save more than $-20? You will find the corresponding connections below.
- 18h 40m
  
  La Serena
  
  7 mi
  
  12:30 AM
  
  Coquimbo
  La Cantera Bus Stop
  
  7:10 PM
  
  Rancagua
  Rodoviario Rancagua
  
  0 mi
  
  Premium Economy
  
  $47
  
  A Bus from goes from La Cantera Bus Stop, Coquimbo (Chile) at 9/13/2026 12:30:00 AM to Rodoviario Rancagua, Rancagua (Chile) arriving at 9/13/2026 7:10:00 PM. 50 Premium Economy ticket for $47 per person are available. Travel duration is 18h 40m
Did you know that if you travel from La Serena to Rancagua via Santiago, RM, you can save more than $12? You can find the corresponding connections below.
- Buses Romani
  
  7h 25m
  
  0
  
  12:45 AM
  
  La Serena
  Central Bus Station
  
  7:00 AM
  
  Santiago, RM
  Sur Bus Station
  
  0
  
  Premium Economy
  
  $11
  
  A Bus from Buses Romani goes from Central Bus Station, La Serena (Chile) at 9/11/2026 12:45:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 9/11/2026 7:00:00 AM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 6h 15m
- Andimar
  
  0h 55m
  
  0
  
  7:15 AM
  
  Santiago, RM
  Sur Bus Station
  
  8:10 AM
  
  Rancagua
  Bus Stop
  
  0
  
  Economy
  
  $4
  
  A Bus from Andimar goes from Sur Bus Station, Santiago, RM (Chile) at 9/11/2026 7:15:00 AM to Bus Stop, Rancagua (Chile) arriving at 9/11/2026 8:10:00 AM. 50 Economy ticket for $4 per person are available. Travel duration is 0h 55m
Travel Time is 0h 30m shorter, and you will save $12

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	8h 35m	11:50 PM	La Serena	Central Bus Station	8:25 AM	Rancagua	Bus Stop	Economy	$22	A Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 9/14/2026 11:50:00 PM to Bus Stop, Rancagua (Chile) arriving at 9/15/2026 8:25:00 AM. 50 Economy ticket for $22 per person are available. Travel duration is 8h 35m
FlixBus	8h 40m	11:50 PM	La Serena	Central Bus Station	8:30 AM	Rancagua	Terminal O'Higgins	Economy	$22	A Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 9/14/2026 11:50:00 PM to Terminal O'Higgins, Rancagua (Chile) arriving at 9/15/2026 8:30:00 AM. 50 Economy ticket for $22 per person are available. Travel duration is 8h 40m
Turbus	18h 5m	1:05 AM	La Serena	Avda. Fco de Aguirre Station	7:10 PM	Rancagua	Rodoviario Rancagua	Premium Economy	$50	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 9/14/2026 1:05:00 AM to Rodoviario Rancagua, Rancagua (Chile) arriving at 9/14/2026 7:10:00 PM. 50 Premium Economy ticket for $50 per person are available. Travel duration is 18h 5m
Turbus	19h 10m	5:55 AM	La Serena	Avda. Fco de Aguirre Station	1:05 AM	Rancagua	Rodoviario Rancagua	Premium Economy	$54	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 9/14/2026 5:55:00 AM to Rodoviario Rancagua, Rancagua (Chile) arriving at 9/15/2026 1:05:00 AM. 50 Premium Economy ticket for $54 per person are available. Travel duration is 19h 10m
Turbus	18h 15m	3:10 PM	La Serena	Avda. Fco de Aguirre Station	9:25 AM	Rancagua	Rodoviario Rancagua	Premium Economy	$54	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 9/14/2026 3:10:00 PM to Rodoviario Rancagua, Rancagua (Chile) arriving at 9/15/2026 9:25:00 AM. 50 Premium Economy ticket for $54 per person are available. Travel duration is 18h 15m

Did you know that if you travel from La Serena to Rancagua via Santiago, RM, you can save more than $7? You can find the corresponding connections below.
- Buses Romani
  
  7h 25m
  
  0
  
  12:45 AM
  
  La Serena
  Central Bus Station
  
  7:00 AM
  
  Santiago, RM
  Sur Bus Station
  
  0
  
  Premium Economy
  
  $11
  
  A Bus from Buses Romani goes from Central Bus Station, La Serena (Chile) at 9/11/2026 12:45:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 9/11/2026 7:00:00 AM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 6h 15m
- Andimar
  
  0h 55m
  
  0
  
  7:15 AM
  
  Santiago, RM
  Sur Bus Station
  
  8:10 AM
  
  Rancagua
  Bus Stop
  
  0
  
  Economy
  
  $4
  
  A Bus from Andimar goes from Sur Bus Station, Santiago, RM (Chile) at 9/11/2026 7:15:00 AM to Bus Stop, Rancagua (Chile) arriving at 9/11/2026 8:10:00 AM. 50 Economy ticket for $4 per person are available. Travel duration is 0h 55m
Travel Time is 1h 10m shorter, and you will save $7

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	8h 35m	11:50 PM	La Serena	Central Bus Station	8:25 AM	Rancagua	Bus Stop	Economy	$22	A Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 9/15/2026 11:50:00 PM to Bus Stop, Rancagua (Chile) arriving at 9/16/2026 8:25:00 AM. 50 Economy ticket for $22 per person are available. Travel duration is 8h 35m
FlixBus	8h 40m	11:50 PM	La Serena	Central Bus Station	8:30 AM	Rancagua	Terminal O'Higgins	Economy	$22	A Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 9/15/2026 11:50:00 PM to Terminal O'Higgins, Rancagua (Chile) arriving at 9/16/2026 8:30:00 AM. 50 Economy ticket for $22 per person are available. Travel duration is 8h 40m
Turbus	11h 35m	6:05 PM	La Serena	Avda. Fco de Aguirre Station	5:40 AM	Rancagua	Rodoviario Rancagua	Premium Economy	$28	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 9/15/2026 6:05:00 PM to Rodoviario Rancagua, Rancagua (Chile) arriving at 9/16/2026 5:40:00 AM. 50 Premium Economy ticket for $28 per person are available. Travel duration is 11h 35m
Turbus	12h 15m	5:55 AM	La Serena	Avda. Fco de Aguirre Station	6:10 PM	Rancagua	Rodoviario Rancagua	Premium Economy	$34	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 9/15/2026 5:55:00 AM to Rodoviario Rancagua, Rancagua (Chile) arriving at 9/15/2026 6:10:00 PM. 50 Premium Economy ticket for $34 per person are available. Travel duration is 12h 15m
Turbus	12h 5m	9:10 AM	La Serena	Avda. Fco de Aguirre Station	9:15 PM	Rancagua	Rodoviario Rancagua	Premium Economy	$34	A Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 9/15/2026 9:10:00 AM to Rodoviario Rancagua, Rancagua (Chile) arriving at 9/15/2026 9:15:00 PM. 50 Premium Economy ticket for $34 per person are available. Travel duration is 12h 5m

Did you know that if you travel from La Serena to Rancagua via Santiago, RM, you can save more than $7? You can find the corresponding connections below.
- Buses Romani
  
  7h 25m
  
  0
  
  12:45 AM
  
  La Serena
  Central Bus Station
  
  7:00 AM
  
  Santiago, RM
  Sur Bus Station
  
  0
  
  Premium Economy
  
  $11
  
  A Bus from Buses Romani goes from Central Bus Station, La Serena (Chile) at 9/11/2026 12:45:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 9/11/2026 7:00:00 AM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 6h 15m
- Andimar
  
  0h 55m
  
  0
  
  7:15 AM
  
  Santiago, RM
  Sur Bus Station
  
  8:10 AM
  
  Rancagua
  Bus Stop
  
  0
  
  Economy
  
  $4
  
  A Bus from Andimar goes from Sur Bus Station, Santiago, RM (Chile) at 9/11/2026 7:15:00 AM to Bus Stop, Rancagua (Chile) arriving at 9/11/2026 8:10:00 AM. 50 Economy ticket for $4 per person are available. Travel duration is 0h 55m
Travel Time is 1h 10m shorter, and you will save $7

Best Price Offer: The price for the cheapest bus from La Serena to Rancagua is $22 on 9/14/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between La Serena and Rancagua

See here how frequent the connections between La Serena and Rancagua are, during different times and days of the week.

Tuesday is the busiest day, with more than 15 daily buses from La Serena to Rancagua. Thursday has instead the fewest connections, with only 6 daily coaches between La Serena and Rancagua.

The busiest time of the day is the Evening, with 40 buses from La Serena to Rancagua, while Morning sees the fewest connections between La Serena and Rancagua, with 6 offers.

Facts about the bus from La Serena to Rancagua

Compare all providers like Turbus and FlixBus that travel 10 times every day by bus from La Serena to Rancagua in one click! Book your bus ticket from La Serena to Rancagua starting from $22!

Cheapest Bus	$22
Fastest Bus	7h 55m
Earliest Bus	5:55 AM
Latest Bus	11:50 PM
Daily Bus Routes	10 Ø
Distance	296.4 miles
Bus Companies	Turbus and FlixBus

Cheapest bus connections from La Serena to Rancagua

Every day, 10 buses from 2 bus companies leave La Serena for Rancagua: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/09/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 09/06

Monday 09/07

Tuesday 09/08

Wednesday 09/09

$48

Thursday 09/10

$48

Friday 09/11

$34

Saturday 09/12

$34

Sunday 09/13

$47

Monday 09/14

$50

Tuesday 09/15

$28

Wednesday 09/16

$37

Thursday 09/17

$50

Friday 09/18

$28

Saturday 09/19

$28

Sunday 09/20

$50

Monday 09/21

$48

Tuesday 09/22

$48

Wednesday 09/23

$48

Thursday 09/24

$48

Friday 09/25

$28

Saturday 09/26

$28

Sunday 09/27

$47

Monday 09/28

$28

Tuesday 09/29

$48

Wednesday 09/30

$28

Thursday 10/01

$48

Friday 10/02

$28

Saturday 10/03

The cheapest time to travel from La Serena to Rancagua

See here on which day and which time of the day you can find the cheapest bus ticket from La Serena to Rancagua, for the next 30 days.

With a price starting from $22, Monday is the cheapest day for a bus from La Serena to Rancagua. Thursday instead is the most expensive day with prices starting from $32.

Evening is the cheapest day time for bus tickets from La Serena to Rancagua, with $22. Morning is the most expensive time of the day with prices starting from $34.

How to save money travelling from La Serena to Rancagua

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from La Serena to Rancagua in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from La Serena to Rancagua, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from La Serena to Rancagua are also emptier.

All bus stations and stops in La Serena and Rancagua

In the map below, you can see where to find all bus stations in La Serena and Rancagua.

Avda. Fco de Aguirre Station

Avenida Francisco de Aguirre 410

Central Bus Station

Avenida El Santo 1475

terminal de buses covalle bus

El Sto, 1060

Rotonda

Terminal O´Higgins

Libertador Bernardo O'Higgins 34

Sur

Manuel Montt

Terminal O'Higgins

Estado

Ocarrol Bus Station

Service and Comfort on the bus from La Serena to Rancagua

Want to know which seat classes are available on the buses from La Serena to Rancagua? Or which bus companies serve the route La Serena to Rancagua? Below you will find answers to your questions.

FAQs about the La Serena to Rancagua bus

How much does a La Serena Rancagua bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $22 and takes 8h 35m to reach Rancagua. Compare offers to save money!

How much could I save by comparing buses from La Serena to Rancagua?

This route is offered by 2 companies with a range of ticket prices between $22 and $56. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Rancagua.

On average, how many connections are available from La Serena to Rancagua each day?

Every day, the La Serena to Rancagua bus route is served by approximately 10 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from La Serena to Rancagua take?

The fastest bus from La Serena to Rancagua is offered by Turbus and takes 7h 55m. Bus tickets for this connection cost $32. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from La Serena to Rancagua?

The earliest bus arriving in Rancagua from La Serena starts at 5:55 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from La Serena to Rancagua?

The latest bus trip departing from La Serena for Rancagua starts at 11:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the La Serena Rancagua route?

When traveling by bus from La Serena to Rancagua, passengers can travel with Turbus and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between La Serena and Rancagua?

You can check all the direct connections between La Serena and Rancagua by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Turbus and FlixBus.

What can I take with me on the La Serena to Rancagua bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the La Serena Rancagua bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the La Serena Rancagua bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from La Serena to Rancagua on your planned travel date.

How does CheckMyBus find the best bus deals from La Serena to Rancagua?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 10 daily trips between La Serena and Rancagua. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from La Serena to Rancagua?

Prices and availability for 10 trips between La Serena and Rancagua change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route La Serena to Rancagua

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

First Class

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to La Serena and to Rancagua

Here’s an overview of the most popular bus routes to La Serena and to Rancagua. Simply click on the connection of your choice, and you will find all the details about your bus route!