Which bus from Antofagasta to La Serena is the cheapest?

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Compare all timetables for the bus from Antofagasta to La Serena

Here is a selection of the cheapest bus trips from the schedule from Antofagasta to La Serena from various bus operators like Pluss Chile, Pullman San Andres or Pullman Bus for the next days.

today
$32
tomorrow
$31
Friday
$31
Saturday
$29
Sunday
$31
Monday
$28
Tuesday
$33

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Pluss Chile 11h 35m 10:30 AM Antofagasta Carlos Oviedo Cavada Bus Station 10:05 PM La Serena Central Bus Station  Premium Economy $32
Pullman San Andres 12h 10m 12:00 PM Antofagasta Carlos Oviedo Cavada Bus Station 12:10 AM La Serena Central Bus Station  Premium Economy $35
Cormar Bus 12h 0m 1:30 PM Antofagasta Camus Bus Station 1:30 AM La Serena Central Bus Station  Premium Economy $36
Pullman Bus 11h 50m 4:30 PM Antofagasta Camus Bus Station 4:20 AM La Serena El Sto, 1060  First Class $36
Andimar 12h 10m 9:50 PM Antofagasta Carlos Oviedo Cavada Bus Station 10:00 AM La Serena Central Bus Station  Economy $40

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Andimar 12h 10m 3:35 AM Antofagasta Carlos Oviedo Cavada Bus Station 3:45 PM La Serena Central Bus Station  Economy $31
Pluss Chile 10h 45m 12:05 AM Antofagasta Carlos Oviedo Cavada Bus Station 10:50 AM La Serena Central Bus Station  Premium Economy $32
Pullman San Andres 12h 10m 12:00 PM Antofagasta Carlos Oviedo Cavada Bus Station 12:10 AM La Serena Central Bus Station  Premium Economy $35
Cormar Bus 12h 0m 1:30 PM Antofagasta Camus Bus Station 1:30 AM La Serena Central Bus Station  Premium Economy $36
Cikbus Elité 11h 20m 3:30 AM Antofagasta Carlos Oviedo Cavada Bus Station 2:50 PM La Serena Central Bus Station  Premium Economy $37

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Andimar 12h 10m 3:35 AM Antofagasta Carlos Oviedo Cavada Bus Station 3:45 PM La Serena Central Bus Station  Economy $31
Pluss Chile 10h 45m 12:05 AM Antofagasta Carlos Oviedo Cavada Bus Station 10:50 AM La Serena Central Bus Station  Premium Economy $32
FlixBus 11h 35m 3:00 AM Antofagasta Carlos Oviedo Cavada Bus Station 2:35 PM La Serena Central Bus Station  Economy $32
Pullman San Andres 12h 10m 12:00 PM Antofagasta Carlos Oviedo Cavada Bus Station 12:10 AM La Serena Central Bus Station  Premium Economy $35
Pullman Bus 11h 50m 4:30 PM Antofagasta Camus Bus Station 4:20 AM La Serena El Sto, 1060  First Class $36

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Andimar 12h 10m 3:35 AM Antofagasta Carlos Oviedo Cavada Bus Station 3:45 PM La Serena Central Bus Station  Economy $29
Cormar Bus 12h 10m 1:50 PM Antofagasta Camus Bus Station 2:00 AM La Serena Central Bus Station  Premium Economy $32
Andimar 12h 10m 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station 1:45 PM La Serena Central Bus Station  Economy $35
Pullman San Andres 12h 10m 12:00 PM Antofagasta Carlos Oviedo Cavada Bus Station 12:10 AM La Serena Central Bus Station  Premium Economy $35
Pullman San Andres 12h 10m 9:30 PM Antofagasta Carlos Oviedo Cavada Bus Station 9:40 AM La Serena Central Bus Station  Premium Economy $35

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Andimar 12h 10m 3:35 AM Antofagasta Carlos Oviedo Cavada Bus Station 3:45 PM La Serena Central Bus Station  Economy $31
FlixBus 11h 35m 3:00 AM Antofagasta Carlos Oviedo Cavada Bus Station 2:35 PM La Serena Central Bus Station  Economy $31
Cormar Bus 12h 10m 1:50 PM Antofagasta Camus Bus Station 2:00 AM La Serena Central Bus Station  Premium Economy $32
Pullman San Andres 12h 10m 12:00 PM Antofagasta Carlos Oviedo Cavada Bus Station 12:10 AM La Serena Central Bus Station  Premium Economy $35
Pullman Bus 11h 50m 4:30 PM Antofagasta Camus Bus Station 4:20 AM La Serena El Sto, 1060  First Class $36

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Andimar 12h 10m 3:35 AM Antofagasta Carlos Oviedo Cavada Bus Station 3:45 PM La Serena Central Bus Station  Economy $28
Pullman San Andres 12h 10m 12:00 PM Antofagasta Carlos Oviedo Cavada Bus Station 12:10 AM La Serena Central Bus Station  Premium Economy $35
Pullman Bus 11h 50m 4:30 PM Antofagasta Camus Bus Station 4:20 AM La Serena El Sto, 1060  First Class $36
Cormar Bus 12h 0m 10:40 AM Antofagasta Camus Bus Station 10:40 PM La Serena Central Bus Station  Premium Economy $36
Cikbus Elité 11h 20m 1:10 AM Antofagasta Carlos Oviedo Cavada Bus Station 12:30 PM La Serena Central Bus Station  Premium Economy $43

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Andimar 12h 10m 3:35 AM Antofagasta Carlos Oviedo Cavada Bus Station 3:45 PM La Serena Central Bus Station  Economy $33
FlixBus 11h 35m 3:00 AM Antofagasta Carlos Oviedo Cavada Bus Station 2:35 PM La Serena Central Bus Station  Economy $33
Pullman San Andres 12h 10m 12:00 PM Antofagasta Carlos Oviedo Cavada Bus Station 12:10 AM La Serena Central Bus Station  Premium Economy $35
Cormar Bus 12h 0m 10:40 AM Antofagasta Camus Bus Station 10:40 PM La Serena Central Bus Station  Premium Economy $36
Pullman Bus 11h 50m 4:30 PM Antofagasta Camus Bus Station 4:20 AM La Serena El Sto, 1060  First Class $36
  • Did you know that if you travel from Antofagasta to La Serena via Vallenar, you can save more than $3? You can find the corresponding connections below.
    • Andimar
      14h 15m
      0
      3:35 AM
      Antofagasta
      Carlos Oviedo Cavada Bus Station
      12:55 PM
      Vallenar
      Bus Station
      0
      Andimar
      Economy
      $22
      • Waiting Time 2h 35m
    • Pullman Bus
      2h 20m
      0
      3:30 PM
      Vallenar
      Bus Stop
      5:50 PM
      La Serena
      El Sto, 1060
      0
      Pullman Bus
      First Class
      $9
    Travel time is 2h 40m longer, but you will save $3

Best Price Offer: The price for the cheapest bus from Antofagasta to La Serena is $26 on 9/30/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Antofagasta and La Serena

See here how frequent the connections between Antofagasta and La Serena are, during different times and days of the week.
Monday is the busiest day, with more than 92 daily buses from Antofagasta to La Serena. Saturday has instead the fewest connections, with only 38 daily coaches between Antofagasta and La Serena.
The busiest time of the day is the Evening, with 214 buses from Antofagasta to La Serena, while Morning sees the fewest connections between Antofagasta and La Serena, with 37 offers.

Facts about the bus from Antofagasta to La Serena

Compare all providers like Pluss Chile, Pullman San Andres and Pullman Bus that travel 70 times every day by bus from Antofagasta to La Serena in one click! Book your bus ticket from Antofagasta to La Serena starting from $26!

Cheapest Bus $26
Fastest Bus 10h 30m
Earliest Bus 10:00 AM
Latest Bus 11:59 PM
Daily Bus Routes 70 Ø
Distance 435.4 miles
Bus Companies Pluss Chile, Pullman San Andres, Pullman Bus, Cormar Bus, Cikbus Elité, Andimar and FlixBus

Cheapest bus connections from Antofagasta to La Serena

Every day, 70 buses from 7 bus companies leave Antofagasta for La Serena: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/09/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 09/06
Monday 09/07
Tuesday 09/08
Wednesday 09/09
$32
Thursday 09/10
$34
Friday 09/11
$30
Saturday 09/12
$29
Sunday 09/13
$31
Monday 09/14
$39
Tuesday 09/15
$33
Wednesday 09/16
$32
Thursday 09/17
$35
Friday 09/18
$30
Saturday 09/19
$30
Sunday 09/20
$29
Monday 09/21
$30
Tuesday 09/22
$27
Wednesday 09/23
$30
Thursday 09/24
$27
Friday 09/25
$27
Saturday 09/26
$28
Sunday 09/27
$28
Monday 09/28
$27
Tuesday 09/29
$27
Wednesday 09/30
$26
Thursday 10/01
$26
Friday 10/02
$27
Saturday 10/03

The cheapest time to travel from Antofagasta to La Serena

See here on which day and which time of the day you can find the cheapest bus ticket from Antofagasta to La Serena, for the next 30 days.
With a price starting from $26, Monday is the cheapest day for a bus from Antofagasta to La Serena. Sunday instead is the most expensive day with prices starting from $28.
Night is the cheapest day time for bus tickets from Antofagasta to La Serena, with $26. Morning is the most expensive time of the day with prices starting from $32.

How to save money travelling from Antofagasta to La Serena

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Antofagasta to La Serena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Antofagasta to La Serena, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Antofagasta to La Serena are also emptier.

Beloved bus companies from Antofagasta to La Serena

These are the most booked bus companies between Antofagasta to La Serena from our users.

Pluss Chile from Antofagasta to La Serena

Pluss Chile

Here you will find the key facts about the Pluss Chile bus route Antofagasta to La Serena:

Cheapest Price $32
Fastest Bus 10h 45m
Earliest Bus 10:30 AM
Last Bus 8:46 PM
Daily Connections 23 Ø
Found on 9/9/2026

FlixBus from Antofagasta to La Serena

FlixBus

Here you will find the key facts about the FlixBus bus route Antofagasta to La Serena:

Cheapest Price $26
Fastest Bus 11h 35m
Earliest Bus 1:35 AM
Last Bus 3:00 AM
Daily Connections 3 Ø
Found on 9/9/2026

Latest reviews for bus companies on the route Antofagasta - La Serena

Pullman San Andres
Axl, 8/13/2026
Me cancelan el viaje y cambian por un horario donde mantenían el salón cama pero el cual no podía porque no tenía mucho tiempo para alistarme, o uno dónde si me daban más tiempo pero no era salon cama ... Me cancelan el viaje y cambian por un horario donde mantenían el salón cama pero el cual no podía porque no tenía mucho tiempo para alistarme, o uno dónde si me daban más tiempo pero no era salon cama si no que semincama y no se me devuelve la diferencia. El bus justo no tenía espacio arriba de mi asiento para guardar la mochila, el aire acondicionado estaba abierto con un hoyo y que rico viajar toda la noche con el aire directo a la cabeza... Considerando que íbamos con nuestra bebé en brazos. Que decir de la atención, le dije al auxiliar pero su solución fue meter un vaso plástico que 0 función cumplió, tuve que moverlo yo para que algo tape el aire, además de que le comenté que había basura del pasajero anterior en el asiento y dijo "ya vengo" se fue y recién al par de horas apareció y cuando le volvimos a decir, solo atinó a dejar la basura arriba de unos asientos más adelante. Desperté con dolor de cabeza y garganta, además de que el baño todo hediondo a meado.
Pullman San Andres
Cecilia Yanet Castro Ordenes, 1/18/2026
Pésima experiencias en Pullman San Andrés. Horarios: atrasos de hasta dos horas. Bus sucio y en mal estado. Al bus le faltaba la puerta del segundo piso y la puerta del baño no se cerraba, golpeándose ... Pésima experiencias en Pullman San Andrés. Horarios: atrasos de hasta dos horas. Bus sucio y en mal estado. Al bus le faltaba la puerta del segundo piso y la puerta del baño no se cerraba, golpeándose durante todo el viaje y dejando salir los malos olores. En la escalera había apoyada una escoba que también golpeaba durante todo el viaje. El chofer muy imprudente en su manejo, poco confortable, exceso de velocidad y frenadas constantes. Además, condujo por más de cinco horas que es lo establecido. Poquísimo personal, no hay a quien solicitar ayuda si la necesitas. No lo recomiendo y me preocupa la falta de fiscalización que permite este tipo de servicio en viajes largos.
Cikbus Elité
Alfonso fuentes , 3/22/2025
Muy mala puntualidad ya que teniamos que salir a las 23:30 horas desde antofagasta y terminamos saliendo a las 12 de la madrugada, ademas de eso el bus venia por gran parte del trayecto a mas de 120 k ... Muy mala puntualidad ya que teniamos que salir a las 23:30 horas desde antofagasta y terminamos saliendo a las 12 de la madrugada, ademas de eso el bus venia por gran parte del trayecto a mas de 120 kmh, ademas de eso se quedan haciendo tiempo en chañaral para poder llegar en el horario indicado ademas de eso me cambiaron el pasaje en 2 oportunidades por problemas con sus maquinas por nada del mundo compren pasajes en cikbus

All bus stations and stops in Antofagasta and La Serena

In the map below, you can see where to find all bus stations in Antofagasta and La Serena.

Service and Comfort on the bus from Antofagasta to La Serena

Want to know which seat classes are available on the buses from Antofagasta to La Serena? Or which bus companies serve the route Antofagasta to La Serena? Below you will find answers to your questions.

FAQs about the Antofagasta to La Serena bus

How much does a Antofagasta La Serena bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $26 and takes 12h 10m to reach La Serena. Compare offers to save money!

How much could I save by comparing buses from Antofagasta to La Serena?

This route is offered by 7 companies with a range of ticket prices between $26 and $69. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to La Serena.

On average, how many connections are available from Antofagasta to La Serena each day?

Every day, the Antofagasta to La Serena bus route is served by approximately 70 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Antofagasta to La Serena take?

The fastest bus from Antofagasta to La Serena is offered by Cormar Bus and takes 10h 30m. Bus tickets for this connection cost $49. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Antofagasta to La Serena?

The earliest bus arriving in La Serena from Antofagasta starts at 10:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Antofagasta to La Serena?

The latest bus trip departing from Antofagasta for La Serena starts at 11:59 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Antofagasta La Serena route?

When traveling by bus from Antofagasta to La Serena, passengers can travel with Pluss Chile, Pullman San Andres and Pullman Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Antofagasta and La Serena?

You can check all the direct connections between Antofagasta and La Serena by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Pluss Chile, Pullman San Andres and Pullman Bus.

What can I take with me on the Antofagasta to La Serena bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Antofagasta La Serena bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Antofagasta La Serena bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Antofagasta to La Serena on your planned travel date.

How does CheckMyBus find the best bus deals from Antofagasta to La Serena?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 70 daily trips between Antofagasta and La Serena. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Antofagasta to La Serena?

Prices and availability for 70 trips between Antofagasta and La Serena change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Antofagasta to La Serena

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Antofagasta and to La Serena

Here’s an overview of the most popular bus routes to Antofagasta and to La Serena. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus to Antofagasta from Coquimbo Bus to Antofagasta from Coquimbo
Buses from Tocopilla to Antofagasta Buses from Tocopilla to Antofagasta
Buses to Antofagasta from Viña del Mar Buses to Antofagasta from Viña del Mar
Bus to Antofagasta from Concepción Bus to Antofagasta from Concepción
Bus from Alto Hospicio to La Serena Bus from Alto Hospicio to La Serena
Bus from Quilpué to La Serena Bus from Quilpué to La Serena
Bus Talca, ML to La Serena Bus Talca, ML to La Serena
Bus Pozo Almonte to La Serena Bus Pozo Almonte to La Serena
CheckMyBus › Buses in Chile › Bus to Antofagasta › Bus to La Serena

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