Bus Frankfurt am Main to Rome - Compare all Companies

Compare all timetables for the bus from Frankfurt am Main to Rome

Here is a selection of the cheapest bus trips from the schedule from Frankfurt am Main to Rome from various bus operators like FlixBus for the next days.

today

$135

tomorrow

$133

Saturday

$111

Sunday

$117

Monday

$76

Tuesday

$70

Wednesday

$81

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	21h 20m	5:45 PM	Frankfurt am Main	Central Station	3:05 PM	Rome	Anagnina Bus Station	Economy	$135	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/22/2026 5:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 10/23/2026 3:05:00 PM. 50 Economy ticket for $135 per person are available. Travel duration is 21h 20m
FlixBus	19h 20m	10:30 PM	Frankfurt am Main	Central Station	5:50 PM	Rome	Anagnina Bus Station	Economy	$160	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/22/2026 10:30:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 10/23/2026 5:50:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 19h 20m
FlixBus	20h 5m	5:45 PM	Frankfurt am Main	Central Station	1:50 PM	Rome	Tiburtina Bus Station	Economy	$194	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/22/2026 5:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 10/23/2026 1:50:00 PM. 50 Economy ticket for $194 per person are available. Travel duration is 20h 5m

Did you know that if you travel from Frankfurt am Main to Rome via Heilbronn, you can save more than $52? You can find the corresponding connections below.
- FlixBus
  
  28h 20m
  
  0
  
  2:45 AM
  
  Frankfurt am Main
  Central Station
  
  6:45 AM
  
  Heilbronn
  Neckarsulm Train Station
  
  0
  
  Economy
  
  $15
  
  A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/23/2026 2:45:00 AM to Neckarsulm Train Station, Heilbronn (Germany) arriving at 10/23/2026 6:45:00 AM. 50 Economy ticket for $15 per person are available. Travel duration is 4h 0m
- FlixBus
  
  24h 15m
  
  0
  
  6:50 AM
  
  Heilbronn
  Neckarsulm Train Station
  
  7:05 AM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Economy
  
  $67
  
  A Bus from FlixBus goes from Neckarsulm Train Station, Heilbronn (Germany) at 10/23/2026 6:50:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 10/24/2026 7:05:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 24h 15m
Travel time is 9h 0m longer, but you will save $52

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	21h 20m	1:40 AM	Frankfurt am Main	Central Station	11:00 PM	Rome	Tiburtina Bus Station	Economy	$133	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/23/2026 1:40:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 10/23/2026 11:00:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 21h 20m
FlixBus	19h 45m	1:45 PM	Frankfurt am Main	Central Station	9:30 AM	Rome	Tiburtina Bus Station	Economy	$133	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/23/2026 1:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 10/24/2026 9:30:00 AM. 50 Economy ticket for $133 per person are available. Travel duration is 19h 45m
FlixBus	20h 0m	5:20 PM	Frankfurt am Main	Central Station	1:20 PM	Rome	Tiburtina Bus Station	Economy	$134	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/23/2026 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 10/24/2026 1:20:00 PM. 50 Economy ticket for $134 per person are available. Travel duration is 20h 0m
FlixBus	21h 40m	12:45 AM	Frankfurt am Main	Central Station	10:25 PM	Rome	Tiburtina Bus Station	Economy	$160	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/23/2026 12:45:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 10/23/2026 10:25:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 21h 40m
FlixBus	21h 5m	8:30 AM	Frankfurt am Main	Central Station	5:35 AM	Rome	Tiburtina Bus Station	Economy	$160	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/23/2026 8:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 10/24/2026 5:35:00 AM. 50 Economy ticket for $160 per person are available. Travel duration is 21h 5m

Did you know that if you travel from Frankfurt am Main to Rome via Heilbronn, you can save more than $50? You can find the corresponding connections below.
- FlixBus
  
  28h 20m
  
  0
  
  2:45 AM
  
  Frankfurt am Main
  Central Station
  
  6:45 AM
  
  Heilbronn
  Neckarsulm Train Station
  
  0
  
  Economy
  
  $15
  
  A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/23/2026 2:45:00 AM to Neckarsulm Train Station, Heilbronn (Germany) arriving at 10/23/2026 6:45:00 AM. 50 Economy ticket for $15 per person are available. Travel duration is 4h 0m
- FlixBus
  
  24h 15m
  
  0
  
  6:50 AM
  
  Heilbronn
  Neckarsulm Train Station
  
  7:05 AM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Economy
  
  $67
  
  A Bus from FlixBus goes from Neckarsulm Train Station, Heilbronn (Germany) at 10/23/2026 6:50:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 10/24/2026 7:05:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 24h 15m
Travel time is 8h 35m longer, but you will save $50

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	21h 20m	1:40 AM	Frankfurt am Main	Central Station	11:00 PM	Rome	Tiburtina Bus Station	Economy	$111	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/24/2026 1:40:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 10/24/2026 11:00:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 21h 20m
FlixBus	19h 45m	1:45 PM	Frankfurt am Main	Central Station	8:30 AM	Rome	Tiburtina Bus Station	Economy	$111	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/24/2026 1:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 10/25/2026 8:30:00 AM. 50 Economy ticket for $111 per person are available. Travel duration is 19h 45m
FlixBus	22h 50m	2:30 PM	Frankfurt am Main	Central Station	12:20 PM	Rome	Tiburtina Bus Station	Economy	$112	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/24/2026 2:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 10/25/2026 12:20:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 22h 50m
FlixBus	21h 0m	3:15 PM	Frankfurt am Main	Central Station	11:15 AM	Rome	Anagnina Bus Station	Economy	$114	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/24/2026 3:15:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 10/25/2026 11:15:00 AM. 50 Economy ticket for $114 per person are available. Travel duration is 21h 0m
FlixBus	21h 35m	8:30 AM	Frankfurt am Main	Central Station	5:05 AM	Rome	Anagnina Bus Station	Economy	$115	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/24/2026 8:30:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 10/25/2026 5:05:00 AM. 50 Economy ticket for $115 per person are available. Travel duration is 21h 35m

Did you know that if you travel from Frankfurt am Main to Rome via Bologna, you can save more than $27? You can find the corresponding connections below.
- FlixBus
  
  22h 0m
  
  0
  
  3:15 PM
  
  Frankfurt am Main
  Central Station
  
  3:25 AM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  0
  
  Economy
  
  $76
  
  A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/24/2026 3:15:00 PM to Piazza XX Settembre Bus Station, Bologna (Italy) arriving at 10/25/2026 3:25:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 13h 10m
- Itabus
  
  5h 15m
  
  0
  
  7:00 AM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  12:15 PM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Premium Economy
  
  $8
  
  A Bus from Itabus goes from Piazza XX Settembre Bus Station, Bologna (Italy) at 10/25/2026 7:00:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 10/25/2026 12:15:00 PM. 50 Premium Economy ticket for $8 per person are available. Travel duration is 5h 15m
Travel time is 3h 15m longer, but you will save $27

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	20h 5m	5:45 PM	Frankfurt am Main	Central Station	1:50 PM	Rome	Tiburtina Bus Station	Economy	$117	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/25/2026 5:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 10/26/2026 1:50:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 20h 5m
FlixBus	22h 50m	2:30 PM	Frankfurt am Main	Central Station	1:20 PM	Rome	Tiburtina Bus Station	Economy	$122	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/25/2026 2:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 10/26/2026 1:20:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 22h 50m
FlixBus	21h 0m	3:15 PM	Frankfurt am Main	Central Station	12:15 PM	Rome	Anagnina Bus Station	Economy	$124	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/25/2026 3:15:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 10/26/2026 12:15:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 21h 0m
FlixBus	18h 55m	10:30 PM	Frankfurt am Main	Central Station	5:25 PM	Rome	Tiburtina Bus Station	Economy	$132	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/25/2026 10:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 10/26/2026 5:25:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 18h 55m
FlixBus	19h 20m	10:30 PM	Frankfurt am Main	Central Station	5:50 PM	Rome	Anagnina Bus Station	Economy	$136	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/25/2026 10:30:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 10/26/2026 5:50:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 19h 20m

Did you know that if you travel from Frankfurt am Main to Rome via Bologna, you can save more than $46? You can find the corresponding connections below.
- FlixBus
  
  20h 0m
  
  0
  
  10:30 PM
  
  Frankfurt am Main
  Central Station
  
  11:10 AM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  0
  
  Economy
  
  $61
  
  A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/26/2026 10:30:00 PM to Piazza XX Settembre Bus Station, Bologna (Italy) arriving at 10/27/2026 11:10:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 12h 40m
- Itabus
  
  5h 50m
  
  0
  
  12:40 PM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  6:30 PM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Economy
  
  $10
  
  A Bus from Itabus goes from Piazza XX Settembre Bus Station, Bologna (Italy) at 10/27/2026 12:40:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 10/27/2026 6:30:00 PM. 50 Economy ticket for $10 per person are available. Travel duration is 5h 50m
Travel time is 1h 5m longer, but you will save $46

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	20h 5m	5:45 PM	Frankfurt am Main	Central Station	1:50 PM	Rome	Tiburtina Bus Station	Economy	$76	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/26/2026 5:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 10/27/2026 1:50:00 PM. 50 Economy ticket for $76 per person are available. Travel duration is 20h 5m
FlixBus	21h 20m	1:40 AM	Frankfurt am Main	Central Station	11:00 PM	Rome	Tiburtina Bus Station	Economy	$83	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/26/2026 1:40:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 10/26/2026 11:00:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 21h 20m
FlixBus	19h 45m	1:45 PM	Frankfurt am Main	Central Station	9:30 AM	Rome	Tiburtina Bus Station	Economy	$83	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/26/2026 1:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 10/27/2026 9:30:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 19h 45m
FlixBus	19h 20m	10:30 PM	Frankfurt am Main	Central Station	5:50 PM	Rome	Anagnina Bus Station	Economy	$84	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/26/2026 10:30:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 10/27/2026 5:50:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 19h 20m
FlixBus	21h 20m	5:45 PM	Frankfurt am Main	Central Station	3:05 PM	Rome	Anagnina Bus Station	Economy	$85	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/26/2026 5:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 10/27/2026 3:05:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 21h 20m

Did you know that if you travel from Frankfurt am Main to Rome via Bologna, you can save more than $10? You can find the corresponding connections below.
- FlixBus
  
  24h 45m
  
  0
  
  5:45 PM
  
  Frankfurt am Main
  Central Station
  
  8:25 AM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  0
  
  Economy
  
  $57
  
  A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/27/2026 5:45:00 PM to Piazza XX Settembre Bus Station, Bologna (Italy) arriving at 10/28/2026 8:25:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 14h 40m
- Itabus
  
  5h 50m
  
  0
  
  12:40 PM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  6:30 PM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Economy
  
  $9
  
  A Bus from Itabus goes from Piazza XX Settembre Bus Station, Bologna (Italy) at 10/28/2026 12:40:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 10/28/2026 6:30:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 5h 50m
Travel time is 5h 25m longer, but you will save $10

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	20h 5m	5:45 PM	Frankfurt am Main	Central Station	1:50 PM	Rome	Tiburtina Bus Station	Economy	$70	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/27/2026 5:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 10/28/2026 1:50:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 20h 5m
FlixBus	19h 45m	1:45 PM	Frankfurt am Main	Central Station	9:30 AM	Rome	Tiburtina Bus Station	Economy	$78	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/27/2026 1:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 10/28/2026 9:30:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 19h 45m
FlixBus	21h 55m	8:10 PM	Frankfurt am Main	Central Station	6:05 PM	Rome	Anagnina Bus Station	Economy	$79	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/27/2026 8:10:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 10/28/2026 6:05:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 21h 55m
FlixBus	22h 50m	2:30 PM	Frankfurt am Main	Central Station	1:20 PM	Rome	Tiburtina Bus Station	Economy	$84	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/27/2026 2:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 10/28/2026 1:20:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 22h 50m
FlixBus	21h 20m	1:40 AM	Frankfurt am Main	Central Station	11:00 PM	Rome	Tiburtina Bus Station	Economy	$86	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/27/2026 1:40:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 10/27/2026 11:00:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 21h 20m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	20h 5m	5:45 PM	Frankfurt am Main	Central Station	1:50 PM	Rome	Tiburtina Bus Station	Economy	$81	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/28/2026 5:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 10/29/2026 1:50:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 20h 5m
FlixBus	21h 20m	1:40 AM	Frankfurt am Main	Central Station	11:00 PM	Rome	Tiburtina Bus Station	Economy	$88	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/28/2026 1:40:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 10/28/2026 11:00:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 21h 20m
FlixBus	19h 45m	1:45 PM	Frankfurt am Main	Central Station	9:30 AM	Rome	Tiburtina Bus Station	Economy	$88	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/28/2026 1:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 10/29/2026 9:30:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 19h 45m
FlixBus	22h 50m	2:30 PM	Frankfurt am Main	Central Station	1:20 PM	Rome	Tiburtina Bus Station	Economy	$90	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/28/2026 2:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 10/29/2026 1:20:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 22h 50m
FlixBus	24h 20m	5:45 PM	Frankfurt am Main	Central Station	6:05 PM	Rome	Anagnina Bus Station	Economy	$96	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/28/2026 5:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 10/29/2026 6:05:00 PM. 50 Economy ticket for $96 per person are available. Travel duration is 24h 20m

Did you know that if you travel from Frankfurt am Main to Rome via Bologna, you can save more than $15? You can find the corresponding connections below.
- FlixBus
  
  24h 45m
  
  0
  
  5:45 PM
  
  Frankfurt am Main
  Central Station
  
  8:25 AM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  0
  
  Economy
  
  $57
  
  A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/27/2026 5:45:00 PM to Piazza XX Settembre Bus Station, Bologna (Italy) arriving at 10/28/2026 8:25:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 14h 40m
- Itabus
  
  5h 50m
  
  0
  
  12:40 PM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  6:30 PM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Economy
  
  $9
  
  A Bus from Itabus goes from Piazza XX Settembre Bus Station, Bologna (Italy) at 10/28/2026 12:40:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 10/28/2026 6:30:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 5h 50m
Travel time is 5h 0m longer, but you will save $15

Best Price Offer: The price for the cheapest bus from Frankfurt am Main to Rome is $58 on 11/10/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Frankfurt am Main and Rome

See here how frequent the connections between Frankfurt am Main and Rome are, during different times and days of the week.

Friday is the busiest day, with more than 14 daily buses from Frankfurt am Main to Rome. Thursday has instead the fewest connections, with only 3 daily coaches between Frankfurt am Main and Rome.

The busiest time of the day is the Afternoon, with 29 buses from Frankfurt am Main to Rome, while Evening sees the fewest connections between Frankfurt am Main and Rome, with 9 offers.

Facts about the bus from Frankfurt am Main to Rome

Compare all providers like FlixBus that travel 10 times every day by bus from Frankfurt am Main to Rome in one click! Book your bus ticket from Frankfurt am Main to Rome starting from $58!

Cheapest Bus	$58
Fastest Bus	18h 45m
Earliest Bus	5:45 PM
Latest Bus	5:45 PM
Daily Bus Routes	10 Ø
Distance	596.0 miles
Bus Companies	FlixBus

Cheapest bus connections from Frankfurt am Main to Rome

Every day, 10 buses from 1 bus companies leave Frankfurt am Main for Rome: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/22/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 10/18

Monday 10/19

Tuesday 10/20

Wednesday 10/21

Thursday 10/22

$135

Friday 10/23

$133

Saturday 10/24

$111

Sunday 10/25

$117

Monday 10/26

$76

Tuesday 10/27

$70

Wednesday 10/28

$81

Thursday 10/29

$79

Friday 10/30

$94

Saturday 10/31

$91

Sunday 11/01

$83

Monday 11/02

$67

Tuesday 11/03

$67

Wednesday 11/04

$60

Thursday 11/05

$72

Friday 11/06

$67

Saturday 11/07

$62

Sunday 11/08

$72

Monday 11/09

$64

Tuesday 11/10

$58

Wednesday 11/11

$64

Thursday 11/12

$70

Friday 11/13

$76

Saturday 11/14

The cheapest time to travel from Frankfurt am Main to Rome

See here on which day and which time of the day you can find the cheapest bus ticket from Frankfurt am Main to Rome, for the next 30 days.

With a price starting from $58, Tuesday is the cheapest day for a bus from Frankfurt am Main to Rome. Sunday instead is the most expensive day with prices starting from $70.

Night is the cheapest day time for bus tickets from Frankfurt am Main to Rome, with $58. Morning is the most expensive time of the day with prices starting from $93.

How to save money travelling from Frankfurt am Main to Rome

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Frankfurt am Main to Rome in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Frankfurt am Main to Rome, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Frankfurt am Main to Rome are also emptier.

Beloved bus companies from Frankfurt am Main to Rome

These are the most booked bus companies between Frankfurt am Main to Rome from our users.

FlixBus from Frankfurt am Main to Rome

Here you will find the key facts about the FlixBus bus route Frankfurt am Main to Rome:

Cheapest Price	$70
Fastest Bus	18h 45m
Earliest Bus	5:45 PM
Last Bus	5:45 PM
Daily Connections	10 Ø
Found on	10/22/2026

All bus stations and stops in Frankfurt am Main and Rome

In the map below, you can see where to find all bus stations in Frankfurt am Main and Rome.

Central Bus Station

Karlsruher Straße 10

Stuttgarter Strasse Bus Stop

Stuttgarter Str.

Seilerstraße Bus Stop

Stresemannallee/Mörfelder Landstr. Bus Stop

Baseler Platz Bus Stop

Anagnina Bus Station

Piazzale della Stazione Anagnina

Termini Bus Station

Piazza dei Cinquecento 64

Tiburtina Bus Station

Tiburtina Partenze

Vatican City

Via Crescenzio 19

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Frankfurt am Main to Rome? Compare all modes of transports from Frankfurt am Main to Rome.

Service and Comfort on the bus from Frankfurt am Main to Rome

Want to know which seat classes are available on the buses from Frankfurt am Main to Rome? Or which bus companies serve the route Frankfurt am Main to Rome? Below you will find answers to your questions.

FAQs about the Frankfurt am Main to Rome bus

How much does a Frankfurt am Main Rome bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $58 and takes 20h 5m to reach Rome. Compare offers to save money!

How much could I save by comparing buses from Frankfurt am Main to Rome?

This route is offered by 1 companies with a range of ticket prices between $58 and $210. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Rome.

On average, how many connections are available from Frankfurt am Main to Rome each day?

Every day, the Frankfurt am Main to Rome bus route is served by approximately 10 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Frankfurt am Main to Rome take?

The fastest bus from Frankfurt am Main to Rome is offered by FlixBus and takes 18h 45m. Bus tickets for this connection cost $111. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Frankfurt am Main to Rome?

The earliest bus arriving in Rome from Frankfurt am Main starts at 5:45 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Frankfurt am Main to Rome?

The latest bus trip departing from Frankfurt am Main for Rome starts at 5:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Frankfurt am Main Rome route?

When traveling by bus from Frankfurt am Main to Rome, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Frankfurt am Main and Rome?

You can check all the direct connections between Frankfurt am Main and Rome by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Frankfurt am Main to Rome bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Frankfurt am Main Rome bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Frankfurt am Main Rome bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Frankfurt am Main to Rome on your planned travel date.

How does CheckMyBus find the best bus deals from Frankfurt am Main to Rome?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 10 daily trips between Frankfurt am Main and Rome. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Frankfurt am Main to Rome?

Prices and availability for 10 trips between Frankfurt am Main and Rome change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Frankfurt am Main to Rome

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Frankfurt am Main and to Rome

Here’s an overview of the most popular bus routes to Frankfurt am Main and to Rome. Simply click on the connection of your choice, and you will find all the details about your bus route!