Bus Chicago to San Luis Potosí - Compare all Companies

Compare all timetables for the bus from Chicago to San Luis Potosí

Here is a selection of the cheapest bus trips from the schedule from Chicago to San Luis Potosí from various bus operators like Greyhound US or FlixBus for the next days.

today

tomorrow

$220

Saturday

$220

Sunday

$215

Monday

$215

Tuesday

Wednesday

$221

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	53h 35m	10:15 AM	Chicago	Union Station	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$220	A Bus from Greyhound US goes from Union Station, Chicago (USA) at 9/11/2026 10:15:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 9/13/2026 2:50:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 53h 35m
FlixBus	46h 0m	9:45 AM	Chicago	Downtown Bus Station	6:45 AM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$221	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 9/11/2026 9:45:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 9/13/2026 6:45:00 AM. 50 Economy ticket for $221 per person are available. Travel duration is 46h 0m
Greyhound US	41h 20m	10:30 PM	Chicago	Downtown Bus Station	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$221	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 9/11/2026 10:30:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 9/13/2026 2:50:00 PM. 50 Economy ticket for $221 per person are available. Travel duration is 41h 20m
Greyhound US	49h 0m	10:50 PM	Chicago	Downtown Bus Station	10:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$257	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 9/11/2026 10:50:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 9/13/2026 10:50:00 PM. 50 Economy ticket for $257 per person are available. Travel duration is 49h 0m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	53h 35m	10:15 AM	Chicago	Union Station	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$220	A Bus from Greyhound US goes from Union Station, Chicago (USA) at 9/12/2026 10:15:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 9/14/2026 2:50:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 53h 35m
Greyhound US	41h 20m	10:30 PM	Chicago	Downtown Bus Station	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$221	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 9/12/2026 10:30:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 9/14/2026 2:50:00 PM. 50 Economy ticket for $221 per person are available. Travel duration is 41h 20m
Greyhound US	49h 0m	10:50 PM	Chicago	Downtown Bus Station	10:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$223	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 9/12/2026 10:50:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 9/14/2026 10:50:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 49h 0m
FlixBus	46h 0m	9:45 AM	Chicago	Downtown Bus Station	6:45 AM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$226	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 9/12/2026 9:45:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 9/14/2026 6:45:00 AM. 50 Economy ticket for $226 per person are available. Travel duration is 46h 0m

Did you know that if you travel from Chicago to San Luis Potosí via McAllen, TX, you can save more than $23? You can find the corresponding connections below.
- FlixBus
  
  58h 20m
  
  0
  
  5:05 PM
  
  Chicago
  Downtown Bus Station
  
  5:55 AM
  
  McAllen, TX
  Central Bus Station
  
  0
  
  Economy
  
  $132
  
  A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 9/13/2026 5:05:00 PM to Central Bus Station, McAllen, TX (USA) arriving at 9/15/2026 5:55:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 36h 50m
- Greyhound US
  
  17h 55m
  
  0
  
  9:30 AM
  
  McAllen, TX
  Central Bus Station
  
  2:25 AM
  
  San Luis Potosí
  Soriana El Paseo Bus Station
  
  0
  
  Economy
  
  $65
  
  A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 9/15/2026 9:30:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 9/16/2026 2:25:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 17h 55m
Travel time is 18h 0m longer, but you will save $23

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	41h 20m	10:30 PM	Chicago	Downtown Bus Station	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$215	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 9/13/2026 10:30:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 9/15/2026 2:50:00 PM. 50 Economy ticket for $215 per person are available. Travel duration is 41h 20m
FlixBus	50h 0m	5:45 AM	Chicago	95th Red Line Station	6:45 AM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$216	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 9/13/2026 5:45:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 9/15/2026 6:45:00 AM. 50 Economy ticket for $216 per person are available. Travel duration is 50h 0m
FlixBus	46h 45m	5:05 PM	Chicago	95th Red Line Station	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$216	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 9/13/2026 5:05:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 9/15/2026 2:50:00 PM. 50 Economy ticket for $216 per person are available. Travel duration is 46h 45m
Greyhound US	53h 35m	10:15 AM	Chicago	Canal & Van Buren	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$217	A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 9/13/2026 10:15:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 9/15/2026 2:50:00 PM. 50 Economy ticket for $217 per person are available. Travel duration is 53h 35m
FlixBus	46h 0m	9:45 AM	Chicago	Downtown Bus Station	6:45 AM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$218	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 9/13/2026 9:45:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 9/15/2026 6:45:00 AM. 50 Economy ticket for $218 per person are available. Travel duration is 46h 0m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	41h 20m	10:30 PM	Chicago	Downtown Bus Station	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$215	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 9/14/2026 10:30:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 9/16/2026 2:50:00 PM. 50 Economy ticket for $215 per person are available. Travel duration is 41h 20m
FlixBus	46h 45m	5:05 PM	Chicago	95th Red Line Station	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$216	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 9/14/2026 5:05:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 9/16/2026 2:50:00 PM. 50 Economy ticket for $216 per person are available. Travel duration is 46h 45m
Greyhound US	53h 35m	10:15 AM	Chicago	Canal & Van Buren	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$217	A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 9/14/2026 10:15:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 9/16/2026 2:50:00 PM. 50 Economy ticket for $217 per person are available. Travel duration is 53h 35m
Greyhound US	48h 40m	11:10 PM	Chicago	Canal & Van Buren	10:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$227	A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 9/14/2026 11:10:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 9/16/2026 10:50:00 PM. 50 Economy ticket for $227 per person are available. Travel duration is 48h 40m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	41h 20m	10:30 PM	Chicago	Downtown Bus Station	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$221	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 9/16/2026 10:30:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 9/18/2026 2:50:00 PM. 50 Economy ticket for $221 per person are available. Travel duration is 41h 20m
FlixBus	46h 0m	9:45 AM	Chicago	Downtown Bus Station	6:45 AM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$224	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 9/16/2026 9:45:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 9/18/2026 6:45:00 AM. 50 Economy ticket for $224 per person are available. Travel duration is 46h 0m
Greyhound US	53h 35m	10:15 AM	Chicago	Union Station	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$229	A Bus from Greyhound US goes from Union Station, Chicago (USA) at 9/16/2026 10:15:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 9/18/2026 2:50:00 PM. 50 Economy ticket for $229 per person are available. Travel duration is 53h 35m

Did you know that if you travel from Chicago to San Luis Potosí via McAllen, TX, you can save more than $36? You can find the corresponding connections below.
- Greyhound US
  
  57h 15m
  
  0
  
  10:30 PM
  
  Chicago
  Downtown Bus Station
  
  11:50 AM
  
  McAllen, TX
  Central Bus Station
  
  0
  
  Economy
  
  $119
  
  A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 9/16/2026 10:30:00 PM to Central Bus Station, McAllen, TX (USA) arriving at 9/18/2026 11:50:00 AM. 50 Economy ticket for $119 per person are available. Travel duration is 37h 20m
- Greyhound US
  
  15h 50m
  
  0
  
  3:55 PM
  
  McAllen, TX
  Central Bus Station
  
  6:45 AM
  
  San Luis Potosí
  Soriana El Paseo Bus Station
  
  0
  
  Economy
  
  $66
  
  A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 9/18/2026 3:55:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 9/19/2026 6:45:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 15h 50m
Travel time is 16h 55m longer, but you will save $36

Best Price Offer: The price for the cheapest bus from Chicago to San Luis Potosí is $215 on 9/8/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Chicago and San Luis Potosí

See here how frequent the connections between Chicago and San Luis Potosí are, during different times and days of the week.

Monday is the busiest day, with more than 10 daily buses from Chicago to San Luis Potosí. Wednesday has instead the fewest connections, with only 3 daily coaches between Chicago and San Luis Potosí.

The busiest time of the day is the Evening, with 18 buses from Chicago to San Luis Potosí, while Night sees the fewest connections between Chicago and San Luis Potosí, with 1 offers.

Facts about the bus from Chicago to San Luis Potosí

Compare all providers like Greyhound US and FlixBus that travel 6 times every day by bus from Chicago to San Luis Potosí in one click! Book your bus ticket from Chicago to San Luis Potosí starting from $215!

Cheapest Bus	$215
Fastest Bus	40h 20m
Earliest Bus	9:45 AM
Latest Bus	10:30 PM
Daily Bus Routes	6 Ø
Distance	1,566.6 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Chicago to San Luis Potosí

Every day, 6 buses from 2 bus companies leave Chicago for San Luis Potosí: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/10/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 09/06

Monday 09/07

Tuesday 09/08

Wednesday 09/09

Thursday 09/10

Friday 09/11

$220

Saturday 09/12

$220

Sunday 09/13

$215

Monday 09/14

$221

Tuesday 09/15

Wednesday 09/16

$221

Thursday 09/17

$216

Friday 09/18

$221

Saturday 09/19

$223

Sunday 09/20

Monday 09/21

$224

Tuesday 09/22

$219

Wednesday 09/23

$219

Thursday 09/24

$223

Friday 09/25

$223

Saturday 09/26

Sunday 09/27

Monday 09/28

$219

Tuesday 09/29

$219

Wednesday 09/30

$219

Thursday 10/01

Friday 10/02

Saturday 10/03

The cheapest time to travel from Chicago to San Luis Potosí

See here on which day and which time of the day you can find the cheapest bus ticket from Chicago to San Luis Potosí, for the next 30 days.

With a price starting from $215, Sunday is the cheapest day for a bus from Chicago to San Luis Potosí. Friday instead is the most expensive day with prices starting from $220.

Afternoon is the cheapest day time for bus tickets from Chicago to San Luis Potosí, with $214. Morning is the most expensive time of the day with prices starting from $217.

How to save money travelling from Chicago to San Luis Potosí

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Chicago to San Luis Potosí in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Chicago to San Luis Potosí, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Chicago to San Luis Potosí are also emptier.

Beloved bus companies from Chicago to San Luis Potosí

These are the most booked bus companies between Chicago to San Luis Potosí from our users.

FlixBus from Chicago to San Luis Potosí

Here you will find the key facts about the FlixBus bus route Chicago to San Luis Potosí:

Cheapest Price	$216
Fastest Bus	45h 0m
Earliest Bus	9:45 AM
Last Bus	9:45 AM
Daily Connections	1 Ø
Found on	8/16/2026

Greyhound US from Chicago to San Luis Potosí

Here you will find the key facts about the Greyhound US bus route Chicago to San Luis Potosí:

Cheapest Price	$215
Fastest Bus	40h 20m
Earliest Bus	10:15 AM
Last Bus	10:30 PM
Daily Connections	4 Ø
Found on	8/16/2026

All bus stations and stops in Chicago and San Luis Potosí

In the map below, you can see where to find all bus stations in Chicago and San Luis Potosí.

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Central Bus Station

Av Benito Juarez 250

Soriana El Paseo Bus Station

Doctor Salvador Nava Martínez 405

Av Constitución / Manual José Othón Bus Stop

Avenida Constitución 300

Barrio de Santiago

Trojes del Horizonte

Service and Comfort on the bus from Chicago to San Luis Potosí

Want to know which seat classes are available on the buses from Chicago to San Luis Potosí? Or which bus companies serve the route Chicago to San Luis Potosí? Below you will find answers to your questions.

FAQs about the Chicago to San Luis Potosí bus

How much does a Chicago San Luis Potosí bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $215 and takes 40h 20m to reach San Luis Potosí. Compare offers to save money!

How much could I save by comparing buses from Chicago to San Luis Potosí?

This route is offered by 2 companies with a range of ticket prices between $215 and $257. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Luis Potosí.

On average, how many connections are available from Chicago to San Luis Potosí each day?

Every day, the Chicago to San Luis Potosí bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Chicago to San Luis Potosí take?

The fastest bus from Chicago to San Luis Potosí is offered by Greyhound US and takes 40h 20m. Bus tickets for this connection cost $221. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Chicago to San Luis Potosí?

The earliest bus arriving in San Luis Potosí from Chicago starts at 9:45 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Chicago to San Luis Potosí?

The latest bus trip departing from Chicago for San Luis Potosí starts at 10:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Chicago San Luis Potosí route?

When traveling by bus from Chicago to San Luis Potosí, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Chicago and San Luis Potosí?

You can check all the direct connections between Chicago and San Luis Potosí by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Chicago to San Luis Potosí bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Chicago San Luis Potosí bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Chicago San Luis Potosí bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Chicago to San Luis Potosí on your planned travel date.

How does CheckMyBus find the best bus deals from Chicago to San Luis Potosí?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Chicago and San Luis Potosí. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Chicago to San Luis Potosí?

Prices and availability for 6 trips between Chicago and San Luis Potosí change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Chicago to San Luis Potosí

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Chicago and to San Luis Potosí

Here’s an overview of the most popular bus routes to Chicago and to San Luis Potosí. Simply click on the connection of your choice, and you will find all the details about your bus route!