Bus San Antonio, TX to Chicago: Compare prices and save money

Compare all timetables for the bus from San Antonio, TX to Chicago

Here is a selection of the cheapest bus trips from the schedule from San Antonio, TX to Chicago from various bus operators like FlixBus, Greyhound US or Greyhound Lines Mexico for the next days.

today

$113

tomorrow

$117

Monday

$114

Tuesday

$111

Wednesday

$117

Thursday

$135

Friday

$110

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	31h 25m	9:55 PM	San Antonio, TX	Bus Station	5:20 AM	Chicago	95th Red Line Station	Economy	$113	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 7/25/2026 9:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/27/2026 5:20:00 AM. 50 Economy ticket for $113 per person are available. Travel duration is 31h 25m
Greyhound US	35h 0m	12:35 PM	San Antonio, TX	Bus Station	11:35 PM	Chicago	95th Red Line Station	Economy	$114	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 7/25/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/26/2026 11:35:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 35h 0m
FlixBus	49h 20m	9:45 AM	San Antonio, TX	Pearl District	11:05 AM	Chicago	95th Red Line Station	Economy	$127	A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 7/25/2026 9:45:00 AM to 95th Red Line Station, Chicago (USA) arriving at 7/27/2026 11:05:00 AM. 50 Economy ticket for $127 per person are available. Travel duration is 49h 20m

Did you know that if you travel from San Antonio, TX to Chicago via Austin, you can save more than $15? You can find the corresponding connections below.
- Greyhound US
  
  27h 50m
  
  0
  
  1:30 AM
  
  San Antonio, TX
  Bus Station
  
  3:00 AM
  
  Austin
  5119 Eastside Bus Plaza
  
  0
  
  Economy
  
  $14
  
  A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 7/27/2026 1:30:00 AM to 5119 Eastside Bus Plaza, Austin (USA) arriving at 7/27/2026 3:00:00 AM. 50 Economy ticket for $14 per person are available. Travel duration is 1h 30m
- Greyhound US
  
  26h 15m
  
  0
  
  3:05 AM
  
  Austin
  5119 Eastside Bus Plaza
  
  5:20 AM
  
  Chicago
  95th Red Line Station
  
  0
  
  Economy
  
  $84
  
  A Bus from Greyhound US goes from 5119 Eastside Bus Plaza, Austin (USA) at 7/27/2026 3:05:00 AM to 95th Red Line Station, Chicago (USA) arriving at 7/28/2026 5:20:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 26h 15m
Travel Time is 3h 35m shorter, and you will save $15

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	31h 25m	9:55 PM	San Antonio, TX	Bus Station	5:20 AM	Chicago	95th Red Line Station	Economy	$117	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 7/26/2026 9:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/28/2026 5:20:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 31h 25m
Greyhound US	35h 0m	12:35 PM	San Antonio, TX	Bus Station	11:35 PM	Chicago	95th Red Line Station	Economy	$117	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 7/26/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/27/2026 11:35:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 35h 0m
FlixBus	34h 55m	7:30 AM	San Antonio, TX	Bus Station	6:25 PM	Chicago	95th Red Line Station	Economy	$120	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 7/26/2026 7:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 7/27/2026 6:25:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 34h 55m
Greyhound Lines Mexico	27h 50m	1:30 AM	San Antonio, TX	Bus Station	5:20 AM	Chicago	95th Red Line Station	Economy	$122	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 7/26/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 7/27/2026 5:20:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 27h 50m

Did you know that if you travel from San Antonio, TX to Chicago via Austin, you can save more than $23? You can find the corresponding connections below.
- FlixBus
  
  35h 25m
  
  0
  
  5:55 PM
  
  San Antonio, TX
  Pearl District
  
  8:10 PM
  
  Austin
  RedCoach Stop
  
  0
  
  Economy
  
  $13
  
  A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 7/27/2026 5:55:00 PM to RedCoach Stop, Austin (USA) arriving at 7/27/2026 8:10:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 2h 15m
- FlixBus
  
  29h 50m
  
  0
  
  11:30 PM
  
  Austin
  5119 Eastside Bus Plaza
  
  5:20 AM
  
  Chicago
  95th Red Line Station
  
  0
  
  Economy
  
  $81
  
  A Bus from FlixBus goes from 5119 Eastside Bus Plaza, Austin (USA) at 7/27/2026 11:30:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/29/2026 5:20:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 29h 50m
Travel time is 7h 35m longer, but you will save $23

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound Lines Mexico	27h 50m	1:30 AM	San Antonio, TX	Bus Station	5:20 AM	Chicago	95th Red Line Station	Economy	$114	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 7/27/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 7/28/2026 5:20:00 AM. 50 Economy ticket for $114 per person are available. Travel duration is 27h 50m
FlixBus	34h 55m	7:30 AM	San Antonio, TX	Bus Station	6:25 PM	Chicago	95th Red Line Station	Economy	$114	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 7/27/2026 7:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 7/28/2026 6:25:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 34h 55m
FlixBus	31h 25m	9:55 PM	San Antonio, TX	Bus Station	5:20 AM	Chicago	95th Red Line Station	Economy	$114	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 7/27/2026 9:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/29/2026 5:20:00 AM. 50 Economy ticket for $114 per person are available. Travel duration is 31h 25m
Greyhound US	35h 0m	12:35 PM	San Antonio, TX	Bus Station	11:35 PM	Chicago	95th Red Line Station	Economy	$114	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 7/27/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/28/2026 11:35:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 35h 0m

Did you know that if you travel from San Antonio, TX to Chicago via Austin, you can save more than $20? You can find the corresponding connections below.
- FlixBus
  
  35h 25m
  
  0
  
  5:55 PM
  
  San Antonio, TX
  Pearl District
  
  8:10 PM
  
  Austin
  RedCoach Stop
  
  0
  
  Economy
  
  $13
  
  A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 7/27/2026 5:55:00 PM to RedCoach Stop, Austin (USA) arriving at 7/27/2026 8:10:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 2h 15m
- FlixBus
  
  29h 50m
  
  0
  
  11:30 PM
  
  Austin
  5119 Eastside Bus Plaza
  
  5:20 AM
  
  Chicago
  95th Red Line Station
  
  0
  
  Economy
  
  $81
  
  A Bus from FlixBus goes from 5119 Eastside Bus Plaza, Austin (USA) at 7/27/2026 11:30:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/29/2026 5:20:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 29h 50m
Travel time is 7h 35m longer, but you will save $20

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	31h 25m	9:55 PM	San Antonio, TX	Bus Station	5:20 AM	Chicago	95th Red Line Station	Economy	$111	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 7/28/2026 9:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/30/2026 5:20:00 AM. 50 Economy ticket for $111 per person are available. Travel duration is 31h 25m
Greyhound US	36h 35m	5:50 AM	San Antonio, TX	Bus Station	6:25 PM	Chicago	95th Red Line Station	Economy	$112	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 7/28/2026 5:50:00 AM to 95th Red Line Station, Chicago (USA) arriving at 7/29/2026 6:25:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 36h 35m
Greyhound US	35h 0m	12:35 PM	San Antonio, TX	Bus Station	11:35 PM	Chicago	95th Red Line Station	Economy	$112	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 7/28/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/29/2026 11:35:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 35h 0m
FlixBus	30h 25m	9:55 PM	San Antonio, TX	Bus Station	4:20 AM	Chicago	Downtown Bus Station	Economy	$129	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 7/28/2026 9:55:00 PM to Downtown Bus Station, Chicago (USA) arriving at 7/30/2026 4:20:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 30h 25m
Tornado Bus Company	24h 16m	11:05 AM	San Antonio, TX	Tornado Bus Company	11:21 AM	Chicago	California & 35th Street Bus Stop	Economy	$255	A Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 7/28/2026 11:05:00 AM to California & 35th Street Bus Stop, Chicago (USA) arriving at 7/29/2026 11:21:00 AM. 50 Economy ticket for $255 per person are available. Travel duration is 24h 16m

Did you know that if you travel from San Antonio, TX to Chicago via Austin, you can save more than $17? You can find the corresponding connections below.
- FlixBus
  
  35h 25m
  
  0
  
  5:55 PM
  
  San Antonio, TX
  Pearl District
  
  8:10 PM
  
  Austin
  RedCoach Stop
  
  0
  
  Economy
  
  $13
  
  A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 7/27/2026 5:55:00 PM to RedCoach Stop, Austin (USA) arriving at 7/27/2026 8:10:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 2h 15m
- FlixBus
  
  29h 50m
  
  0
  
  11:30 PM
  
  Austin
  5119 Eastside Bus Plaza
  
  5:20 AM
  
  Chicago
  95th Red Line Station
  
  0
  
  Economy
  
  $81
  
  A Bus from FlixBus goes from 5119 Eastside Bus Plaza, Austin (USA) at 7/27/2026 11:30:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/29/2026 5:20:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 29h 50m
Travel time is 11h 9m longer, but you will save $17

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound Lines Mexico	27h 50m	1:30 AM	San Antonio, TX	Bus Station	5:20 AM	Chicago	95th Red Line Station	Economy	$117	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 7/29/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 7/30/2026 5:20:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 27h 50m
Greyhound Lines Mexico	37h 50m	5:50 AM	San Antonio, TX	Bus Station	7:40 PM	Chicago	95th Red Line Station	Economy	$117	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 7/29/2026 5:50:00 AM to 95th Red Line Station, Chicago (USA) arriving at 7/30/2026 7:40:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 37h 50m
Greyhound US	35h 0m	12:35 PM	San Antonio, TX	Bus Station	11:35 PM	Chicago	95th Red Line Station	Economy	$117	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 7/29/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/30/2026 11:35:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 35h 0m
FlixBus	51h 20m	7:45 AM	San Antonio, TX	Pearl District	11:05 AM	Chicago	95th Red Line Station	Economy	$126	A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 7/29/2026 7:45:00 AM to 95th Red Line Station, Chicago (USA) arriving at 7/31/2026 11:05:00 AM. 50 Economy ticket for $126 per person are available. Travel duration is 51h 20m

Did you know that if you travel from San Antonio, TX to Chicago via Austin, you can save more than $23? You can find the corresponding connections below.
- FlixBus
  
  35h 25m
  
  0
  
  5:55 PM
  
  San Antonio, TX
  Pearl District
  
  8:10 PM
  
  Austin
  RedCoach Stop
  
  0
  
  Economy
  
  $13
  
  A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 7/27/2026 5:55:00 PM to RedCoach Stop, Austin (USA) arriving at 7/27/2026 8:10:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 2h 15m
- FlixBus
  
  29h 50m
  
  0
  
  11:30 PM
  
  Austin
  5119 Eastside Bus Plaza
  
  5:20 AM
  
  Chicago
  95th Red Line Station
  
  0
  
  Economy
  
  $81
  
  A Bus from FlixBus goes from 5119 Eastside Bus Plaza, Austin (USA) at 7/27/2026 11:30:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/29/2026 5:20:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 29h 50m
Travel time is 7h 35m longer, but you will save $23

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Valley Transit	32h 20m	9:00 PM	San Antonio, TX	Bus Station	5:20 AM	Chicago	95th Red Line Station	Economy	$135	A Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 7/30/2026 9:00:00 PM to 95th Red Line Station, Chicago (USA) arriving at 8/1/2026 5:20:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 32h 20m
FlixBus	34h 55m	7:30 AM	San Antonio, TX	Bus Station	6:25 PM	Chicago	95th Red Line Station	Economy	$138	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 7/30/2026 7:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 7/31/2026 6:25:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 34h 55m
FlixBus	34h 40m	7:45 AM	San Antonio, TX	Pearl District	6:25 PM	Chicago	95th Red Line Station	Economy	$138	A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 7/30/2026 7:45:00 AM to 95th Red Line Station, Chicago (USA) arriving at 7/31/2026 6:25:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 34h 40m
Greyhound US	27h 50m	1:30 AM	San Antonio, TX	Bus Station	5:20 AM	Chicago	95th Red Line Station	Economy	$144	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 7/30/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 7/31/2026 5:20:00 AM. 50 Economy ticket for $144 per person are available. Travel duration is 27h 50m
Greyhound US	35h 0m	12:35 PM	San Antonio, TX	Bus Station	11:35 PM	Chicago	95th Red Line Station	Economy	$150	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 7/30/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/31/2026 11:35:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 35h 0m

Did you know that if you travel from San Antonio, TX to Chicago via Austin, you can save more than $41? You can find the corresponding connections below.
- FlixBus
  
  35h 25m
  
  0
  
  5:55 PM
  
  San Antonio, TX
  Pearl District
  
  8:10 PM
  
  Austin
  RedCoach Stop
  
  0
  
  Economy
  
  $13
  
  A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 7/27/2026 5:55:00 PM to RedCoach Stop, Austin (USA) arriving at 7/27/2026 8:10:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 2h 15m
- FlixBus
  
  29h 50m
  
  0
  
  11:30 PM
  
  Austin
  5119 Eastside Bus Plaza
  
  5:20 AM
  
  Chicago
  95th Red Line Station
  
  0
  
  Economy
  
  $81
  
  A Bus from FlixBus goes from 5119 Eastside Bus Plaza, Austin (USA) at 7/27/2026 11:30:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/29/2026 5:20:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 29h 50m
Travel time is 7h 35m longer, but you will save $41

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	27h 50m	1:30 AM	San Antonio, TX	Bus Station	5:20 AM	Chicago	95th Red Line Station	Economy	$110	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 7/31/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 8/1/2026 5:20:00 AM. 50 Economy ticket for $110 per person are available. Travel duration is 27h 50m
FlixBus	31h 25m	9:55 PM	San Antonio, TX	Bus Station	5:20 AM	Chicago	95th Red Line Station	Economy	$110	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 7/31/2026 9:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 8/2/2026 5:20:00 AM. 50 Economy ticket for $110 per person are available. Travel duration is 31h 25m
Greyhound US	35h 0m	12:35 PM	San Antonio, TX	Bus Station	11:35 PM	Chicago	95th Red Line Station	Economy	$111	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 7/31/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 8/1/2026 11:35:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 35h 0m
FlixBus	34h 55m	7:30 AM	San Antonio, TX	Bus Station	6:25 PM	Chicago	95th Red Line Station	Economy	$123	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 7/31/2026 7:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 8/1/2026 6:25:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 34h 55m
Tornado Bus Company	24h 16m	11:05 AM	San Antonio, TX	Tornado Bus Company	11:21 AM	Chicago	California & 35th Street Bus Stop	Economy	$255	A Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 7/31/2026 11:05:00 AM to California & 35th Street Bus Stop, Chicago (USA) arriving at 8/1/2026 11:21:00 AM. 50 Economy ticket for $255 per person are available. Travel duration is 24h 16m

Did you know that if you travel from San Antonio, TX to Chicago via Austin, you can save more than $16? You can find the corresponding connections below.
- FlixBus
  
  35h 25m
  
  0
  
  5:55 PM
  
  San Antonio, TX
  Pearl District
  
  8:10 PM
  
  Austin
  RedCoach Stop
  
  0
  
  Economy
  
  $13
  
  A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 7/27/2026 5:55:00 PM to RedCoach Stop, Austin (USA) arriving at 7/27/2026 8:10:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 2h 15m
- FlixBus
  
  29h 50m
  
  0
  
  11:30 PM
  
  Austin
  5119 Eastside Bus Plaza
  
  5:20 AM
  
  Chicago
  95th Red Line Station
  
  0
  
  Economy
  
  $81
  
  A Bus from FlixBus goes from 5119 Eastside Bus Plaza, Austin (USA) at 7/27/2026 11:30:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/29/2026 5:20:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 29h 50m
Travel time is 11h 9m longer, but you will save $16

Best Price Offer: The price for the cheapest bus from San Antonio, TX to Chicago is $93 on 7/19/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between San Antonio, TX and Chicago

See here how frequent the connections between San Antonio, TX and Chicago are, during different times and days of the week.

Thursday is the busiest day, with more than 34 daily buses from San Antonio, TX to Chicago. Saturday has instead the fewest connections, with only 3 daily coaches between San Antonio, TX and Chicago.

The busiest time of the day is the Morning, with 36 buses from San Antonio, TX to Chicago, while Afternoon sees the fewest connections between San Antonio, TX and Chicago, with 15 offers.

Facts about the bus from San Antonio, TX to Chicago

Compare all providers like FlixBus, Greyhound US and Greyhound Lines Mexico that travel 13 times every day by bus from San Antonio, TX to Chicago in one click! Book your bus ticket from San Antonio, TX to Chicago starting from $93!

Cheapest Bus	$93
Fastest Bus	23h 7m
Earliest Bus	9:45 AM
Latest Bus	9:55 PM
Daily Bus Routes	13 Ø
Distance	1,052.2 miles
Bus Companies	FlixBus, Greyhound US, Greyhound Lines Mexico, Tornado Bus Company and Valley Transit

Cheapest bus connections from San Antonio, TX to Chicago

Every day, 13 buses from 5 bus companies leave San Antonio, TX for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/25/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/19

Monday 07/20

Tuesday 07/21

Wednesday 07/22

Thursday 07/23

Friday 07/24

Saturday 07/25

$113

Sunday 07/26

$117

Monday 07/27

$114

Tuesday 07/28

$111

Wednesday 07/29

$117

Thursday 07/30

$135

Friday 07/31

$110

Saturday 08/01

$121

Sunday 08/02

$120

Monday 08/03

$96

Tuesday 08/04

$127

Wednesday 08/05

$121

Thursday 08/06

Friday 08/07

$105

Saturday 08/08

$145

Sunday 08/09

Monday 08/10

$99

Tuesday 08/11

Wednesday 08/12

Thursday 08/13

$114

Friday 08/14

$114

Saturday 08/15

The cheapest time to travel from San Antonio, TX to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from San Antonio, TX to Chicago, for the next 30 days.

With a price starting from $96, Monday is the cheapest day for a bus from San Antonio, TX to Chicago. Wednesday instead is the most expensive day with prices starting from $117.

Night is the cheapest day time for bus tickets from San Antonio, TX to Chicago, with $96. Morning is the most expensive time of the day with prices starting from $114.

How to save money travelling from San Antonio, TX to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Antonio, TX to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Antonio, TX to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Antonio, TX to Chicago are also emptier.

Beloved bus companies from San Antonio, TX to Chicago

These are the most booked bus companies between San Antonio, TX to Chicago from our users.

FlixBus from San Antonio, TX to Chicago

Here you will find the key facts about the FlixBus bus route San Antonio, TX to Chicago:

Cheapest Price	$110
Fastest Bus	30h 25m
Earliest Bus	9:45 AM
Last Bus	9:55 PM
Daily Connections	5 Ø
Found on	7/17/2026

Greyhound Lines Mexico from San Antonio, TX to Chicago

Here you will find the key facts about the Greyhound Lines Mexico bus route San Antonio, TX to Chicago:

Cheapest Price	$114
Fastest Bus	26h 50m
Earliest Bus	1:30 AM
Last Bus	5:50 AM
Daily Connections	2 Ø
Found on	7/17/2026

Valley Transit from San Antonio, TX to Chicago

Here you will find the key facts about the Valley Transit bus route San Antonio, TX to Chicago:

Cheapest Price	$135
Fastest Bus	31h 20m
Earliest Bus	9:00 PM
Last Bus	9:00 PM
Daily Connections	5 Ø
Found on	7/17/2026

All bus stations and stops in San Antonio, TX and Chicago

In the map below, you can see where to find all bus stations in San Antonio, TX and Chicago.

Bus Station

N St Mary's St 500

San Antonio

Pearl District

Avenue A 699-599

Commerce & Bowie Bus Stop

W. Southcross & Buffalo Bus Stop

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Canal & Van Buren

S Canal St 310-320

W Cermak Rd

W Cermak Rd 1001

Service and Comfort on the bus from San Antonio, TX to Chicago

Want to know which seat classes are available on the buses from San Antonio, TX to Chicago? Or which bus companies serve the route San Antonio, TX to Chicago? Below you will find answers to your questions.

FAQs about the San Antonio, TX to Chicago bus

How much does a San Antonio, TX Chicago bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $93 and takes 27h 50m to reach Chicago. Compare offers to save money!

How much could I save by comparing buses from San Antonio, TX to Chicago?

This route is offered by 5 companies with a range of ticket prices between $93 and $255. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.

On average, how many connections are available from San Antonio, TX to Chicago each day?

Every day, the San Antonio, TX to Chicago bus route is served by approximately 13 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Antonio, TX to Chicago take?

The fastest bus from San Antonio, TX to Chicago is offered by Tornado Bus Company and takes 23h 7m. Bus tickets for this connection cost $255. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Antonio, TX to Chicago?

The earliest bus arriving in Chicago from San Antonio, TX starts at 9:45 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Antonio, TX to Chicago?

The latest bus trip departing from San Antonio, TX for Chicago starts at 9:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Antonio, TX Chicago route?

When traveling by bus from San Antonio, TX to Chicago, passengers can travel with FlixBus, Greyhound US and Greyhound Lines Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Antonio, TX and Chicago?

You can check all the direct connections between San Antonio, TX and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound US and Greyhound Lines Mexico.

What can I take with me on the San Antonio, TX to Chicago bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Antonio, TX Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Antonio, TX Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Antonio, TX to Chicago on your planned travel date.

How does CheckMyBus find the best bus deals from San Antonio, TX to Chicago?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 13 daily trips between San Antonio, TX and Chicago. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Antonio, TX to Chicago?

Prices and availability for 13 trips between San Antonio, TX and Chicago change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Antonio, TX to Chicago

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Antonio, TX and to Chicago

Here’s an overview of the most popular bus routes to San Antonio, TX and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!