Bus from Winston-Salem, NC to San Antonio, TX from $109

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Compare all timetables for the bus from Winston-Salem, NC to San Antonio, TX

Here is a selection of the cheapest bus trips from the schedule from Winston-Salem, NC to San Antonio, TX from various bus operators like Greyhound US for the next days.

today
tomorrow
$116
Tuesday
$131
Wednesday
$133
Thursday
Friday
Saturday

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 31h 10m 4:35 PM Winston-Salem, NC Greyhound Bus Station 10:45 PM San Antonio, TX Bus Station  Economy $116
Greyhound US 36h 5m 5:55 PM Winston-Salem, NC Greyhound Bus Station 5:00 AM San Antonio, TX Bus Station  Economy $116
Greyhound US 51h 30m 5:55 PM Winston-Salem, NC Greyhound Bus Station 8:25 PM San Antonio, TX Pearl District  Economy $118
Greyhound US 30h 0m 10:20 AM Winston-Salem, NC Greyhound Bus Station 3:20 PM San Antonio, TX Bus Station  Economy $121

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 30h 0m 10:20 AM Winston-Salem, NC Greyhound Bus Station 3:20 PM San Antonio, TX Bus Station  Economy $131
Greyhound US 32h 20m 4:35 PM Winston-Salem, NC Greyhound Bus Station 11:55 PM San Antonio, TX Bus Station  Economy $131
Greyhound US 36h 5m 5:55 PM Winston-Salem, NC Greyhound Bus Station 5:00 AM San Antonio, TX Bus Station  Economy $132
  • Did you know that if you travel from Winston-Salem, NC to San Antonio, TX via Charlotte, you can save more than $17? You can find the corresponding connections below.
    • Greyhound US
      32h 20m
      0
      4:35 PM
      Winston-Salem, NC
      Greyhound Bus Station
      5:55 PM
      Charlotte
      W Trade St
      0
      Greyhound US
      Economy
      $16
      • Waiting Time 0h 25m
    • Greyhound US
      30h 35m
      0
      6:20 PM
      Charlotte
      W Trade St
      11:55 PM
      San Antonio, TX
      Bus Station
      0
      Greyhound US
      Economy
      $97
    Travel time is 3h 20m longer, but you will save $17

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 36h 5m 5:55 PM Winston-Salem, NC Greyhound Bus Station 5:00 AM San Antonio, TX Bus Station  Economy $133
Greyhound US 51h 30m 5:55 PM Winston-Salem, NC Greyhound Bus Station 8:25 PM San Antonio, TX Pearl District  Economy $134
Greyhound US 32h 20m 4:35 PM Winston-Salem, NC Greyhound Bus Station 11:55 PM San Antonio, TX Bus Station  Economy $138
Greyhound US 30h 0m 10:20 AM Winston-Salem, NC Greyhound Bus Station 3:20 PM San Antonio, TX Bus Station  Economy $140
  • Did you know that if you travel from Winston-Salem, NC to San Antonio, TX via Charlotte, you can save more than $19? You can find the corresponding connections below.
    • Greyhound US
      32h 20m
      0
      4:35 PM
      Winston-Salem, NC
      Greyhound Bus Station
      5:55 PM
      Charlotte
      W Trade St
      0
      Greyhound US
      Economy
      $16
      • Waiting Time 0h 25m
    • Greyhound US
      30h 35m
      0
      6:20 PM
      Charlotte
      W Trade St
      11:55 PM
      San Antonio, TX
      Bus Station
      0
      Greyhound US
      Economy
      $97
    Travel time is 3h 20m longer, but you will save $19

Best Price Offer: The price for the cheapest bus from Winston-Salem, NC to San Antonio, TX is $109 on 8/16/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Winston-Salem, NC and San Antonio, TX

See here how frequent the connections between Winston-Salem, NC and San Antonio, TX are, during different times and days of the week.
Monday is the busiest day, with more than 8 daily buses from Winston-Salem, NC to San Antonio, TX. Wednesday has instead the fewest connections, with only 4 daily coaches between Winston-Salem, NC and San Antonio, TX.
The busiest time of the day is the Afternoon, with 13 buses from Winston-Salem, NC to San Antonio, TX, while Morning sees the fewest connections between Winston-Salem, NC and San Antonio, TX, with 5 offers.

Facts about the bus from Winston-Salem, NC to San Antonio, TX

Compare all providers like Greyhound US that travel 6 times every day by bus from Winston-Salem, NC to San Antonio, TX in one click! Book your bus ticket from Winston-Salem, NC to San Antonio, TX starting from $109!

Cheapest Bus $109
Fastest Bus 29h 0m
Earliest Bus 10:20 AM
Latest Bus 5:55 PM
Daily Bus Routes 6 Ø
Distance 1,153.7 miles
Bus Companies Greyhound US

Cheapest bus connections from Winston-Salem, NC to San Antonio, TX

Every day, 6 buses from 1 bus companies leave Winston-Salem, NC for San Antonio, TX: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/26/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 07/26
Monday 07/27
$120
Tuesday 07/28
$135
Wednesday 07/29
$133
Thursday 07/30
Friday 07/31
Saturday 08/01
Sunday 08/02
$121
Monday 08/03
$116
Tuesday 08/04
$120
Wednesday 08/05
$125
Thursday 08/06
Friday 08/07
$124
Saturday 08/08
$128
Sunday 08/09
$120
Monday 08/10
$128
Tuesday 08/11
$120
Wednesday 08/12
Thursday 08/13
Friday 08/14
Saturday 08/15
$112
Sunday 08/16
$109
Monday 08/17
Tuesday 08/18
Wednesday 08/19
$110
Thursday 08/20
$115
Friday 08/21
Saturday 08/22

The cheapest time to travel from Winston-Salem, NC to San Antonio, TX

See here on which day and which time of the day you can find the cheapest bus ticket from Winston-Salem, NC to San Antonio, TX, for the next 30 days.
With a price starting from $110, Wednesday is the cheapest day for a bus from Winston-Salem, NC to San Antonio, TX. Tuesday instead is the most expensive day with prices starting from $120.
Afternoon is the cheapest day time for bus tickets from Winston-Salem, NC to San Antonio, TX, with $116. Morning is the most expensive time of the day with prices starting from $121.

How to save money travelling from Winston-Salem, NC to San Antonio, TX

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Winston-Salem, NC to San Antonio, TX in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Winston-Salem, NC to San Antonio, TX, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Winston-Salem, NC to San Antonio, TX are also emptier.

Beloved bus companies from Winston-Salem, NC to San Antonio, TX

These are the most booked bus companies between Winston-Salem, NC to San Antonio, TX from our users.

Greyhound US from Winston-Salem, NC to San Antonio, TX

Greyhound US

Here you will find the key facts about the Greyhound US bus route Winston-Salem, NC to San Antonio, TX:

Cheapest Price $116
Fastest Bus 29h 0m
Earliest Bus 10:20 AM
Last Bus 5:55 PM
Daily Connections 6 Ø
Found on 6/28/2026

All bus stations and stops in Winston-Salem, NC and San Antonio, TX

In the map below, you can see where to find all bus stations in Winston-Salem, NC and San Antonio, TX.

Service and Comfort on the bus from Winston-Salem, NC to San Antonio, TX

Want to know which seat classes are available on the buses from Winston-Salem, NC to San Antonio, TX? Or which bus companies serve the route Winston-Salem, NC to San Antonio, TX? Below you will find answers to your questions.

FAQs about the Winston-Salem, NC to San Antonio, TX bus

How much does a Winston-Salem, NC San Antonio, TX bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $109 and takes 35h 5m to reach San Antonio, TX. Compare offers to save money!

How much could I save by comparing buses from Winston-Salem, NC to San Antonio, TX?

This route is offered by 1 companies with a range of ticket prices between $109 and $140. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Antonio, TX.

On average, how many connections are available from Winston-Salem, NC to San Antonio, TX each day?

Every day, the Winston-Salem, NC to San Antonio, TX bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Winston-Salem, NC to San Antonio, TX take?

The fastest bus from Winston-Salem, NC to San Antonio, TX is offered by Greyhound US and takes 29h 0m. Bus tickets for this connection cost $121. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Winston-Salem, NC to San Antonio, TX?

The earliest bus arriving in San Antonio, TX from Winston-Salem, NC starts at 10:20 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Winston-Salem, NC to San Antonio, TX?

The latest bus trip departing from Winston-Salem, NC for San Antonio, TX starts at 5:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Winston-Salem, NC San Antonio, TX route?

When traveling by bus from Winston-Salem, NC to San Antonio, TX, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Winston-Salem, NC and San Antonio, TX?

You can check all the direct connections between Winston-Salem, NC and San Antonio, TX by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Winston-Salem, NC to San Antonio, TX bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Winston-Salem, NC San Antonio, TX bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Winston-Salem, NC San Antonio, TX bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Winston-Salem, NC to San Antonio, TX on your planned travel date.

How does CheckMyBus find the best bus deals from Winston-Salem, NC to San Antonio, TX?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Winston-Salem, NC and San Antonio, TX. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Winston-Salem, NC to San Antonio, TX?

Prices and availability for 6 trips between Winston-Salem, NC and San Antonio, TX change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Winston-Salem, NC to San Antonio, TX

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Winston-Salem, NC and to San Antonio, TX

Here’s an overview of the most popular bus routes to Winston-Salem, NC and to San Antonio, TX. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Winston-Salem, NC and to San Antonio, TX
CheckMyBus › Buses in USA › Bus to Winston-Salem, NC › Bus to San Antonio, TX

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