Bus St. Louis, MO to Mexico City: Compare prices and save money

Compare all timetables for the bus from St. Louis, MO to Mexico City

Here is a selection of the cheapest bus trips from the schedule from St. Louis, MO to Mexico City from various bus operators like Greyhound US or FlixBus for the next days.

today

tomorrow

$154

Saturday

$147

Sunday

$145

Monday

$149

Tuesday

Wednesday

$169

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	47h 0m	4:00 PM	St. Louis, MO	Gateway Station	2:00 PM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$154	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 10/23/2026 4:00:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 10/25/2026 2:00:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 47h 0m
FlixBus	46h 35m	4:00 PM	St. Louis, MO	Gateway Station	1:35 PM	Mexico City	Fórum Buenavista	Economy	$155	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 10/23/2026 4:00:00 PM to Fórum Buenavista, Mexico City (Mexico) arriving at 10/25/2026 1:35:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 46h 35m
Greyhound US	53h 30m	1:20 AM	St. Louis, MO	Gateway Station	5:50 AM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$157	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/23/2026 1:20:00 AM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 10/25/2026 5:50:00 AM. 50 Economy ticket for $157 per person are available. Travel duration is 53h 30m
Greyhound US	54h 15m	5:15 PM	St. Louis, MO	Gateway Station	10:30 PM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$158	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/23/2026 5:15:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 10/25/2026 10:30:00 PM. 50 Economy ticket for $158 per person are available. Travel duration is 54h 15m
Greyhound US	53h 50m	5:15 PM	St. Louis, MO	Gateway Station	10:05 PM	Mexico City	Fórum Buenavista	Economy	$158	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/23/2026 5:15:00 PM to Fórum Buenavista, Mexico City (Mexico) arriving at 10/25/2026 10:05:00 PM. 50 Economy ticket for $158 per person are available. Travel duration is 53h 50m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	45h 45m	1:20 AM	St. Louis, MO	Gateway Station	10:05 PM	Mexico City	Fórum Buenavista	Economy	$147	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/24/2026 1:20:00 AM to Fórum Buenavista, Mexico City (Mexico) arriving at 10/25/2026 10:05:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 45h 45m
Greyhound US	46h 10m	1:20 AM	St. Louis, MO	Gateway Station	10:30 PM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$147	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/24/2026 1:20:00 AM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 10/25/2026 10:30:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 46h 10m
FlixBus	54h 40m	11:45 PM	St. Louis, MO	Gateway Station	5:25 AM	Mexico City	Fórum Buenavista	Economy	$147	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 10/24/2026 11:45:00 PM to Fórum Buenavista, Mexico City (Mexico) arriving at 10/27/2026 5:25:00 AM. 50 Economy ticket for $147 per person are available. Travel duration is 54h 40m
FlixBus	55h 5m	11:45 PM	St. Louis, MO	Gateway Station	5:50 AM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$147	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 10/24/2026 11:45:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 10/27/2026 5:50:00 AM. 50 Economy ticket for $147 per person are available. Travel duration is 55h 5m
FlixBus	47h 0m	4:00 PM	St. Louis, MO	Gateway Station	2:00 PM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$152	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 10/24/2026 4:00:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 10/26/2026 2:00:00 PM. 50 Economy ticket for $152 per person are available. Travel duration is 47h 0m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	47h 0m	4:00 PM	St. Louis, MO	Gateway Station	2:00 PM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$145	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 10/25/2026 4:00:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 10/27/2026 2:00:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 47h 0m
Greyhound US	54h 40m	11:45 PM	St. Louis, MO	Gateway Station	5:25 AM	Mexico City	Fórum Buenavista	Economy	$146	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/25/2026 11:45:00 PM to Fórum Buenavista, Mexico City (Mexico) arriving at 10/28/2026 5:25:00 AM. 50 Economy ticket for $146 per person are available. Travel duration is 54h 40m
FlixBus	46h 35m	4:00 PM	St. Louis, MO	Gateway Station	1:35 PM	Mexico City	Fórum Buenavista	Economy	$147	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 10/25/2026 4:00:00 PM to Fórum Buenavista, Mexico City (Mexico) arriving at 10/27/2026 1:35:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 46h 35m
Greyhound US	55h 5m	11:45 PM	St. Louis, MO	Gateway Station	5:50 AM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$148	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/25/2026 11:45:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 10/28/2026 5:50:00 AM. 50 Economy ticket for $148 per person are available. Travel duration is 55h 5m
Greyhound US	54h 15m	5:15 PM	St. Louis, MO	Gateway Station	10:30 PM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$150	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/25/2026 5:15:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 10/27/2026 10:30:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 54h 15m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	46h 10m	1:20 AM	St. Louis, MO	Gateway Station	10:30 PM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$149	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/26/2026 1:20:00 AM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 10/27/2026 10:30:00 PM. 50 Economy ticket for $149 per person are available. Travel duration is 46h 10m
Greyhound US	54h 15m	5:15 PM	St. Louis, MO	Gateway Station	10:30 PM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$149	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/26/2026 5:15:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 10/28/2026 10:30:00 PM. 50 Economy ticket for $149 per person are available. Travel duration is 54h 15m
Greyhound US	45h 45m	1:20 AM	St. Louis, MO	Gateway Station	10:05 PM	Mexico City	Fórum Buenavista	Economy	$149	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/26/2026 1:20:00 AM to Fórum Buenavista, Mexico City (Mexico) arriving at 10/27/2026 10:05:00 PM. 50 Economy ticket for $149 per person are available. Travel duration is 45h 45m
FlixBus	50h 5m	4:00 PM	St. Louis, MO	Gateway Station	5:05 PM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$150	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 10/26/2026 4:00:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 10/28/2026 5:05:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 50h 5m
FlixBus	49h 40m	4:00 PM	St. Louis, MO	Gateway Station	4:40 PM	Mexico City	Fórum Buenavista	Economy	$150	A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 10/26/2026 4:00:00 PM to Fórum Buenavista, Mexico City (Mexico) arriving at 10/28/2026 4:40:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 49h 40m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	46h 10m	1:20 AM	St. Louis, MO	Gateway Station	10:30 PM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$169	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/28/2026 1:20:00 AM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 10/29/2026 10:30:00 PM. 50 Economy ticket for $169 per person are available. Travel duration is 46h 10m
Greyhound US	45h 45m	1:20 AM	St. Louis, MO	Gateway Station	10:05 PM	Mexico City	Fórum Buenavista	Economy	$169	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/28/2026 1:20:00 AM to Fórum Buenavista, Mexico City (Mexico) arriving at 10/29/2026 10:05:00 PM. 50 Economy ticket for $169 per person are available. Travel duration is 45h 45m
Greyhound US	54h 15m	5:15 PM	St. Louis, MO	Gateway Station	10:30 PM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$171	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/28/2026 5:15:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 10/30/2026 10:30:00 PM. 50 Economy ticket for $171 per person are available. Travel duration is 54h 15m
Greyhound US	53h 50m	5:15 PM	St. Louis, MO	Gateway Station	10:05 PM	Mexico City	Fórum Buenavista	Economy	$171	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/28/2026 5:15:00 PM to Fórum Buenavista, Mexico City (Mexico) arriving at 10/30/2026 10:05:00 PM. 50 Economy ticket for $171 per person are available. Travel duration is 53h 50m
Greyhound US	54h 40m	11:45 PM	St. Louis, MO	Gateway Station	5:25 AM	Mexico City	Fórum Buenavista	Economy	$174	A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 10/28/2026 11:45:00 PM to Fórum Buenavista, Mexico City (Mexico) arriving at 10/31/2026 5:25:00 AM. 50 Economy ticket for $174 per person are available. Travel duration is 54h 40m

Best Price Offer: The price for the cheapest bus from St. Louis, MO to Mexico City is $126 on 11/11/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between St. Louis, MO and Mexico City

See here how frequent the connections between St. Louis, MO and Mexico City are, during different times and days of the week.

Wednesday is the busiest day, with more than 14 daily buses from St. Louis, MO to Mexico City. Sunday has instead the fewest connections, with only 8 daily coaches between St. Louis, MO and Mexico City.

The busiest time of the day is the Afternoon, with 20 buses from St. Louis, MO to Mexico City, while Morning sees the fewest connections between St. Louis, MO and Mexico City, with 4 offers.

Facts about the bus from St. Louis, MO to Mexico City

Compare all providers like Greyhound US and FlixBus that travel 9 times every day by bus from St. Louis, MO to Mexico City in one click! Book your bus ticket from St. Louis, MO to Mexico City starting from $126!

Cheapest Bus	$126
Fastest Bus	44h 45m
Earliest Bus	1:20 AM
Latest Bus	11:45 PM
Daily Bus Routes	9 Ø
Distance	1,430.1 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from St. Louis, MO to Mexico City

Every day, 9 buses from 2 bus companies leave St. Louis, MO for Mexico City: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/22/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 10/18

Monday 10/19

Tuesday 10/20

Wednesday 10/21

Thursday 10/22

Friday 10/23

$154

Saturday 10/24

$147

Sunday 10/25

$145

Monday 10/26

$149

Tuesday 10/27

Wednesday 10/28

$173

Thursday 10/29

$153

Friday 10/30

Saturday 10/31

$145

Sunday 11/01

Monday 11/02

$158

Tuesday 11/03

$171

Wednesday 11/04

$178

Thursday 11/05

$143

Friday 11/06

$137

Saturday 11/07

Sunday 11/08

$135

Monday 11/09

$133

Tuesday 11/10

$148

Wednesday 11/11

$126

Thursday 11/12

Friday 11/13

Saturday 11/14

The cheapest time to travel from St. Louis, MO to Mexico City

See here on which day and which time of the day you can find the cheapest bus ticket from St. Louis, MO to Mexico City, for the next 30 days.

With a price starting from $126, Wednesday is the cheapest day for a bus from St. Louis, MO to Mexico City. Friday instead is the most expensive day with prices starting from $137.

Night is the cheapest day time for bus tickets from St. Louis, MO to Mexico City, with $126. Morning is the most expensive time of the day with prices starting from $198.

How to save money travelling from St. Louis, MO to Mexico City

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from St. Louis, MO to Mexico City in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from St. Louis, MO to Mexico City, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from St. Louis, MO to Mexico City are also emptier.

All bus stations and stops in St. Louis, MO and Mexico City

In the map below, you can see where to find all bus stations in St. Louis, MO and Mexico City.

Gateway Station

S 15th St 430

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Lindbergh @ Hackberry NB Bus Stop

Norte Bus Station

Eje Central Lázaro Cárdenas

Terminal de Autobuses de Oriente (TAPO)

Calz. Ignacio Zaragoza 200

Observatorio Central Bus Station

Av Río de Tacubaya 122 232

Terminal del Sur

Av. Taxqueña 1320

Eje Central Bus Stop

Avenida Lázaro Cárdenas & Calle Poniente 112 Avenida Lázaro Cárdenas & Calle Poniente 112

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from St. Louis, MO to Mexico City? Compare all modes of transports from St. Louis, MO to Mexico City.

Service and Comfort on the bus from St. Louis, MO to Mexico City

Want to know which seat classes are available on the buses from St. Louis, MO to Mexico City? Or which bus companies serve the route St. Louis, MO to Mexico City? Below you will find answers to your questions.

FAQs about the St. Louis, MO to Mexico City bus

How much does a St. Louis, MO Mexico City bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $126 and takes 46h 0m to reach Mexico City. Compare offers to save money!

How much could I save by comparing buses from St. Louis, MO to Mexico City?

This route is offered by 2 companies with a range of ticket prices between $126 and $199. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Mexico City.

On average, how many connections are available from St. Louis, MO to Mexico City each day?

Every day, the St. Louis, MO to Mexico City bus route is served by approximately 9 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from St. Louis, MO to Mexico City take?

The fastest bus from St. Louis, MO to Mexico City is offered by Greyhound US and takes 44h 45m. Bus tickets for this connection cost $179. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from St. Louis, MO to Mexico City?

The earliest bus arriving in Mexico City from St. Louis, MO starts at 1:20 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from St. Louis, MO to Mexico City?

The latest bus trip departing from St. Louis, MO for Mexico City starts at 11:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the St. Louis, MO Mexico City route?

When traveling by bus from St. Louis, MO to Mexico City, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between St. Louis, MO and Mexico City?

You can check all the direct connections between St. Louis, MO and Mexico City by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the St. Louis, MO to Mexico City bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the St. Louis, MO Mexico City bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the St. Louis, MO Mexico City bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from St. Louis, MO to Mexico City on your planned travel date.

How does CheckMyBus find the best bus deals from St. Louis, MO to Mexico City?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 9 daily trips between St. Louis, MO and Mexico City. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from St. Louis, MO to Mexico City?

Prices and availability for 9 trips between St. Louis, MO and Mexico City change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route St. Louis, MO to Mexico City

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to St. Louis, MO and to Mexico City

Here’s an overview of the most popular bus routes to St. Louis, MO and to Mexico City. Simply click on the connection of your choice, and you will find all the details about your bus route!