Compare all timetables for the bus from Siena to Milan
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 5h 45m | 10:55 AM | Siena | Train Station | 4:40 PM | Milan | Lampugnano Bus Station | Premium Economy | $10 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 7/23/2026 10:55:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/23/2026 4:40:00 PM. 50 Premium Economy ticket for $10 per person are available. Travel duration is 5h 45m
|
||
| Itabus | 4h 55m | 1:55 PM | Siena | Train Station | 6:50 PM | Milan | San Donato Bus Station | Premium Economy | $13 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 7/23/2026 1:55:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/23/2026 6:50:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 4h 55m
|
||
| FlixBus | 5h 19m | 6:40 PM | Siena | Train Station | 11:59 PM | Milan | Lampugnano Bus Station | Economy | $21 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 7/23/2026 6:40:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/23/2026 11:59:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 5h 19m
|
||
| FlixBus | 4h 50m | 4:05 PM | Siena | Train Station | 8:55 PM | Milan | San Donato Bus Station | Economy | $21 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 7/23/2026 4:05:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/23/2026 8:55:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 4h 50m
|
||
| Itabus | 7h 30m | 1:55 PM | Siena | Central Bus Station | 9:25 PM | Milan | Lampugnano Bus Station | Economy | $22 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 7/23/2026 1:55:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/23/2026 9:25:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 7h 30m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 7h 30m | 1:55 PM | Siena | Train Station | 9:25 PM | Milan | Lampugnano Bus Station | Premium Economy | $34 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 7/24/2026 1:55:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/24/2026 9:25:00 PM. 50 Premium Economy ticket for $34 per person are available. Travel duration is 7h 30m
|
||
| Itabus | 4h 55m | 1:55 PM | Siena | Train Station | 6:50 PM | Milan | San Donato Bus Station | Economy | $43 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 7/24/2026 1:55:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/24/2026 6:50:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 4h 55m
|
||
| FlixBus | 6h 4m | 2:51 PM | Siena | Bus Stop | 8:55 PM | Milan | San Donato Bus Station | Economy | $45 |
A Bus from FlixBus goes from Bus Stop, Siena (Italy) at 7/24/2026 2:51:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/24/2026 8:55:00 PM. 50 Economy ticket for $45 per person are available. Travel duration is 6h 4m
|
||
| Itabus | 5h 50m | 1:05 AM | Siena | Train Station | 6:55 AM | Milan | Lampugnano Bus Station | Premium Economy | $65 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 7/24/2026 1:05:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/24/2026 6:55:00 AM. 50 Premium Economy ticket for $65 per person are available. Travel duration is 5h 50m
|
-
-
MarinoBus6h 45m04:50 PMSienaTrain Station5:50 PMFlorenceVilla Costanza Bus Station0EconomyA Bus from MarinoBus goes from Train Station, Siena (Italy) at 7/25/2026 4:50:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 7/25/2026 5:50:00 PM. 50 Economy ticket for $10 per person are available. Travel duration is 1h 0m
-
FlixBus4h 50m06:45 PMFlorenceVilla Costanza Bus Station11:35 PMMilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 7/25/2026 6:45:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/25/2026 11:35:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 4h 50m
Waiting Time 0h 55m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 5h 45m | 10:55 AM | Siena | Train Station | 4:40 PM | Milan | Lampugnano Bus Station | Premium Economy | $10 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 7/25/2026 10:55:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/25/2026 4:40:00 PM. 50 Premium Economy ticket for $10 per person are available. Travel duration is 5h 45m
|
||
| Itabus | 4h 55m | 1:55 PM | Siena | Train Station | 6:50 PM | Milan | San Donato Bus Station | Premium Economy | $19 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 7/25/2026 1:55:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/25/2026 6:50:00 PM. 50 Premium Economy ticket for $19 per person are available. Travel duration is 4h 55m
|
||
| Itabus | 7h 30m | 1:55 PM | Siena | Train Station | 9:25 PM | Milan | Lampugnano Bus Station | Premium Economy | $23 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 7/25/2026 1:55:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/25/2026 9:25:00 PM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 7h 30m
|
||
| Itabus | 5h 50m | 1:05 AM | Siena | Train Station | 6:55 AM | Milan | Lampugnano Bus Station | Premium Economy | $29 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 7/25/2026 1:05:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/25/2026 6:55:00 AM. 50 Premium Economy ticket for $29 per person are available. Travel duration is 5h 50m
|
||
| Itabus | 6h 35m | 1:05 AM | Siena | Train Station | 7:40 AM | Milan | San Donato Bus Station | Premium Economy | $76 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 7/25/2026 1:05:00 AM to San Donato Bus Station, Milan (Italy) arriving at 7/25/2026 7:40:00 AM. 50 Premium Economy ticket for $76 per person are available. Travel duration is 6h 35m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 5h 45m | 10:55 AM | Siena | Central Bus Station | 4:40 PM | Milan | Lampugnano Bus Station | Economy | $21 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 7/26/2026 10:55:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/26/2026 4:40:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 5h 45m
|
||
| FlixBus | 5h 19m | 6:40 PM | Siena | Train Station | 11:59 PM | Milan | Lampugnano Bus Station | Economy | $26 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 7/26/2026 6:40:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/26/2026 11:59:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 5h 19m
|
||
| FlixBus | 6h 10m | 5:25 PM | Siena | Train Station | 11:35 PM | Milan | Lampugnano Bus Station | Economy | $27 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 7/26/2026 5:25:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/26/2026 11:35:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 6h 10m
|
||
| FlixBus | 4h 50m | 4:05 PM | Siena | Train Station | 8:55 PM | Milan | San Donato Bus Station | Economy | $30 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 7/26/2026 4:05:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/26/2026 8:55:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 4h 50m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 4h 50m | 6:40 AM | Siena | Train Station | 11:30 AM | Milan | San Donato Bus Station | Economy | $16 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 7/27/2026 6:40:00 AM to San Donato Bus Station, Milan (Italy) arriving at 7/27/2026 11:30:00 AM. 50 Economy ticket for $16 per person are available. Travel duration is 4h 50m
|
||
| FlixBus | 6h 10m | 5:25 PM | Siena | Train Station | 11:35 PM | Milan | Lampugnano Bus Station | Economy | $17 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 7/27/2026 5:25:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/27/2026 11:35:00 PM. 50 Economy ticket for $17 per person are available. Travel duration is 6h 10m
|
||
| Itabus | 5h 45m | 10:55 AM | Siena | Train Station | 4:40 PM | Milan | Lampugnano Bus Station | Economy | $20 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 7/27/2026 10:55:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/27/2026 4:40:00 PM. 50 Economy ticket for $20 per person are available. Travel duration is 5h 45m
|
||
| FlixBus | 5h 55m | 7:50 AM | Siena | Train Station | 1:45 PM | Milan | Lampugnano Bus Station | Economy | $21 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 7/27/2026 7:50:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/27/2026 1:45:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 5h 55m
|
||
| Itabus | 4h 55m | 1:55 PM | Siena | Train Station | 6:50 PM | Milan | San Donato Bus Station | Premium Economy | $23 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 7/27/2026 1:55:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/27/2026 6:50:00 PM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 4h 55m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 5h 45m | 10:55 AM | Siena | Train Station | 4:40 PM | Milan | Lampugnano Bus Station | Premium Economy | $13 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 7/28/2026 10:55:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/28/2026 4:40:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 5h 45m
|
||
| Itabus | 7h 30m | 1:55 PM | Siena | Train Station | 9:25 PM | Milan | Lampugnano Bus Station | Premium Economy | $23 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 7/28/2026 1:55:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/28/2026 9:25:00 PM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 7h 30m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 5h 45m | 10:55 AM | Siena | Train Station | 4:40 PM | Milan | Lampugnano Bus Station | Premium Economy | $19 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 7/29/2026 10:55:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/29/2026 4:40:00 PM. 50 Premium Economy ticket for $19 per person are available. Travel duration is 5h 45m
|
||
| Itabus | 4h 55m | 1:55 PM | Siena | Train Station | 6:50 PM | Milan | San Donato Bus Station | Premium Economy | $19 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 7/29/2026 1:55:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/29/2026 6:50:00 PM. 50 Premium Economy ticket for $19 per person are available. Travel duration is 4h 55m
|
||
| FlixBus | 5h 19m | 6:40 PM | Siena | Train Station | 11:59 PM | Milan | Lampugnano Bus Station | Economy | $21 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 7/29/2026 6:40:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/29/2026 11:59:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 5h 19m
|
||
| FlixBus | 5h 40m | 12:15 PM | Siena | Train Station | 5:55 PM | Milan | Lampugnano Bus Station | Economy | $22 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 7/29/2026 12:15:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/29/2026 5:55:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 5h 40m
|
||
| FlixBus | 5h 55m | 7:50 AM | Siena | Train Station | 1:45 PM | Milan | Lampugnano Bus Station | Economy | $23 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 7/29/2026 7:50:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/29/2026 1:45:00 PM. 50 Economy ticket for $23 per person are available. Travel duration is 5h 55m
|
Best Price Offer: The price for the cheapest bus from Siena to Milan is $8 on 7/21/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Siena and Milan
Facts about the bus from Siena to Milan
Compare all providers like Itabus and FlixBus that travel 18 times every day by bus from Siena to Milan in one click! Book your bus ticket from Siena to Milan starting from $8!
| Cheapest Bus | $8 |
| Fastest Bus | 4h 30m |
| Earliest Bus | 10:55 AM |
| Latest Bus | 6:40 PM |
| Daily Bus Routes | 18 Ø |
| Distance | 182.3 miles |
| Bus Companies | Itabus and FlixBus |
Cheapest bus connections from Siena to Milan
Every day, 18 buses from 2 bus companies leave Siena for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/23/2026 and for the following days.
The cheapest time to travel from Siena to Milan
How to save money travelling from Siena to Milan
Book the ticket from Siena to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Siena to Milan, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Siena to Milan are also emptier.All bus stations and stops in Siena and Milan
In the map below, you can see where to find all bus stations in Siena and Milan.
Service and Comfort on the bus from Siena to Milan
FAQs about the Siena to Milan bus
How much does a Siena Milan bus trip cost?
How much could I save by comparing buses from Siena to Milan?
On average, how many connections are available from Siena to Milan each day?
How long does a bus journey from Siena to Milan take?
What time is the first bus from Siena to Milan?
What time is the last bus from Siena to Milan?
Which bus companies operate the Siena Milan route?
Is there a direct bus between Siena and Milan?
What can I take with me on the Siena to Milan bus route?
What equipment is available for the Siena Milan bus route?
How does CheckMyBus find the best bus deals from Siena to Milan?
How does CheckMyBus technology work for trips from Siena to Milan?
Available seat classes which are offered on the bus route Siena to Milan
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
More bus routes to Siena and to Milan
- Bus Routes to Siena
- Bus Bologna to Siena
- Buses from Caserta to Siena
- Bus Civitavecchia - Siena
- Bus from Cosenza to Siena
- From La Spezia to Siena bus
- Buses from Lauria to Siena
- Buses from Montecatini Terme to Siena
- Bus from Munich to Siena
- Buses from Naples to Siena
- Bus Perugia - Siena
- Bus Pescara to Siena
- Buses to Siena from Pisa
- Buses Poggibonsi to Siena
- Prato to Siena bus
- Bus Sala Consilina - Siena
- Buses Salerno to Siena
- Buses San Gimignano - Siena
- Buses Sesto San Giovanni - Siena
- Buses Taranto - Siena
- Bus Turin - Siena
- Bus Routes to Milan
- Buses Bern to Milan
- From Bolzano to Milan bus
- Bus Brescia to Milan
- Bus Chamonix to Milan
- Bus Foggia - Milan
- Buses Folgarida - Milan
- Bus to Milan from Frankfurt am Main
- Buses to Milan from Ljubljana
- Bus to Milan from Lucerne
- From Padua to Milan bus
- From Paris to Milan bus
- Bus to Milan from Pavia
- Bus to Milan from Prague
- Buses Sallanches - Milan
- From Serravalle Scrivia to Milan bus
- Bus Trento to Milan
- Buses from Venice to Milan
- Buses from Visp to Milan
- Bus Zug - Milan
- Buses from Zurich to Milan
