Bus San Francisco to Myrtle Beach, SC: Compare prices and save money

Compare all timetables for the bus from San Francisco to Myrtle Beach, SC

Here is a selection of the cheapest bus trips from the schedule from San Francisco to Myrtle Beach, SC from various bus operators like Greyhound US or FlixBus for the next days.

today

tomorrow

Saturday

Sunday

Monday

$221

Tuesday

Wednesday

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	71h 40m	1:10 PM	San Francisco	Bus Station Transbay	3:50 PM	Myrtle Beach, SC	Bus Stop	Economy	$221	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 9/14/2026 1:10:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 9/17/2026 3:50:00 PM. 50 Economy ticket for $221 per person are available. Travel duration is 71h 40m
FlixBus	77h 40m	7:10 AM	San Francisco	5th/Townsend	3:50 PM	Myrtle Beach, SC	Bus Stop	Economy	$224	A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 9/14/2026 7:10:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 9/17/2026 3:50:00 PM. 50 Economy ticket for $224 per person are available. Travel duration is 77h 40m
Greyhound US	86h 20m	10:30 PM	San Francisco	Bus Station Transbay	3:50 PM	Myrtle Beach, SC	Bus Stop	Economy	$259	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 9/14/2026 10:30:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 9/18/2026 3:50:00 PM. 50 Economy ticket for $259 per person are available. Travel duration is 86h 20m

Did you know that if you travel from San Francisco to Myrtle Beach, SC via Atlanta, GA, you can save more than $28? You can find the corresponding connections below.
- FlixBus
  
  101h 40m
  
  0
  
  7:10 AM
  
  San Francisco
  5th/Townsend
  
  11:15 PM
  
  Atlanta, GA
  Garnett Transit Station
  
  0
  
  Economy
  
  $154
  
  A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 9/15/2026 7:10:00 AM to Garnett Transit Station, Atlanta, GA (USA) arriving at 9/17/2026 11:15:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 61h 5m
- Greyhound US
  
  8h 40m
  
  0
  
  7:10 AM
  
  Atlanta, GA
  Garnett Transit Station
  
  3:50 PM
  
  Myrtle Beach, SC
  Bus Stop
  
  0
  
  Economy
  
  $39
  
  A Bus from Greyhound US goes from Garnett Transit Station, Atlanta, GA (USA) at 9/19/2026 7:10:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 9/19/2026 3:50:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 8h 40m
Travel time is 27h 0m longer, but you will save $28

Best Price Offer: The price for the cheapest bus from San Francisco to Myrtle Beach, SC is $221 on 9/14/2026. Flexible travelers save on ticket prices.

Facts about the bus from San Francisco to Myrtle Beach, SC

Compare all providers like Greyhound US and FlixBus that travel 3 times every day by bus from San Francisco to Myrtle Beach, SC in one click! Book your bus ticket from San Francisco to Myrtle Beach, SC starting from $221!

Cheapest Bus	$221
Fastest Bus	74h 40m
Earliest Bus	7:10 AM
Latest Bus	10:30 PM
Daily Bus Routes	3 Ø
Distance	2,435.5 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from San Francisco to Myrtle Beach, SC

Every day, 3 buses from 2 bus companies leave San Francisco for Myrtle Beach, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/10/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 09/06

Monday 09/07

Tuesday 09/08

Wednesday 09/09

Thursday 09/10

Friday 09/11

Saturday 09/12

Sunday 09/13

Monday 09/14

$221

Tuesday 09/15

Wednesday 09/16

Thursday 09/17

$224

Friday 09/18

Saturday 09/19

$221

Sunday 09/20

$234

Monday 09/21

Tuesday 09/22

Wednesday 09/23

$226

Thursday 09/24

$223

Friday 09/25

$227

Saturday 09/26

Sunday 09/27

Monday 09/28

Tuesday 09/29

Wednesday 09/30

Thursday 10/01

Friday 10/02

Saturday 10/03

How to save money travelling from San Francisco to Myrtle Beach, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Francisco to Myrtle Beach, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Francisco to Myrtle Beach, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Francisco to Myrtle Beach, SC are also emptier.

Beloved bus companies from San Francisco to Myrtle Beach, SC

These are the most booked bus companies between San Francisco to Myrtle Beach, SC from our users.

FlixBus from San Francisco to Myrtle Beach, SC

Here you will find the key facts about the FlixBus bus route San Francisco to Myrtle Beach, SC:

Cheapest Price	$224
Fastest Bus	80h 40m
Earliest Bus	7:10 AM
Last Bus	7:10 AM
Daily Connections	1 Ø
Found on	8/14/2026

All bus stations and stops in San Francisco and Myrtle Beach, SC

In the map below, you can see where to find all bus stations in San Francisco and Myrtle Beach, SC.

South Van Ness Ave & Market St

5th/Townsend

Townsend St 400

Bus Station Transbay

Folsom Street 200

Union Square

Post St 470

Beach St & Hyde St

Bus Stop

7th Ave N 511

Service and Comfort on the bus from San Francisco to Myrtle Beach, SC

Want to know which seat classes are available on the buses from San Francisco to Myrtle Beach, SC? Or which bus companies serve the route San Francisco to Myrtle Beach, SC? Below you will find answers to your questions.

FAQs about the San Francisco to Myrtle Beach, SC bus

How much does a San Francisco Myrtle Beach, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $221 and takes 74h 40m to reach Myrtle Beach, SC. Compare offers to save money!

How much could I save by comparing buses from San Francisco to Myrtle Beach, SC?

This route is offered by 2 companies with a range of ticket prices between $221 and $259. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Myrtle Beach, SC.

On average, how many connections are available from San Francisco to Myrtle Beach, SC each day?

Every day, the San Francisco to Myrtle Beach, SC bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Francisco to Myrtle Beach, SC take?

The fastest bus from San Francisco to Myrtle Beach, SC is offered by Greyhound US and takes 74h 40m. Bus tickets for this connection cost $221. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Francisco to Myrtle Beach, SC?

The earliest bus arriving in Myrtle Beach, SC from San Francisco starts at 7:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Francisco to Myrtle Beach, SC?

The latest bus trip departing from San Francisco for Myrtle Beach, SC starts at 10:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Francisco Myrtle Beach, SC route?

When traveling by bus from San Francisco to Myrtle Beach, SC, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Francisco and Myrtle Beach, SC?

You can check all the direct connections between San Francisco and Myrtle Beach, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the San Francisco to Myrtle Beach, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Francisco Myrtle Beach, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Francisco Myrtle Beach, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Francisco to Myrtle Beach, SC on your planned travel date.

How does CheckMyBus find the best bus deals from San Francisco to Myrtle Beach, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between San Francisco and Myrtle Beach, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Francisco to Myrtle Beach, SC?

Prices and availability for 3 trips between San Francisco and Myrtle Beach, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Francisco to Myrtle Beach, SC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Francisco and to Myrtle Beach, SC

Here’s an overview of the most popular bus routes to San Francisco and to Myrtle Beach, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!