Bus from Rome to Prague from $76

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Compare all timetables for the bus from Rome to Prague

Here is a selection of the cheapest bus trips from the schedule from Rome to Prague from various bus operators like FlixBus for the next days.

today
$128
tomorrow
$130
Saturday
$117
Sunday
$111
Monday
$99
Tuesday
$100
Wednesday
$103

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 24h 35m 12:45 PM Rome Anagnina Bus Station 1:20 PM Prague Roztyly  Economy $128
FlixBus 26h 50m 5:00 PM Rome Tiburtina Bus Station 7:50 PM Prague Zličín  Economy $137
FlixBus 25h 45m 5:25 PM Rome Anagnina Bus Station 7:10 PM Prague Na Knížecí Station  Economy $139
FlixBus 24h 10m 5:25 PM Rome Anagnina Bus Station 5:35 PM Prague Hradčanská  Economy $145
FlixBus 24h 30m 5:05 PM Rome Tiburtina Bus Station 5:35 PM Prague Hradčanská  Economy $148
  • Did you know that if you travel from Rome to Prague via Udine, you can save more than $41? You can find the corresponding connections below.
    • Itabus
      29h 46m
      0
      11:59 PM
      Rome
      Tiburtina Bus Station
      9:10 AM
      Udine
      Central Bus Station
      0
      Itabus
      Premium Economy
      $39
      • Waiting Time 9h 50m
    • FlixBus
      10h 45m
      0
      7:00 PM
      Udine
      Train Station
      4:45 AM
      Prague
      ÚAN Florenc
      0
      FlixBus
      Economy
      $47
    Travel time is 5h 36m longer, but you will save $41

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 22h 15m 7:30 AM Rome Tiburtina Bus Station 5:45 AM Prague ÚAN Florenc  Economy $130
FlixBus 25h 0m 12:20 PM Rome Tiburtina Bus Station 1:20 PM Prague Roztyly  Economy $143
FlixBus 25h 25m 12:20 PM Rome Tiburtina Bus Station 1:45 PM Prague Černý Most  Economy $144
FlixBus 24h 25m 12:20 PM Rome Tiburtina Bus Station 12:45 PM Prague Na Knížecí Station  Economy $146
FlixBus 20h 40m 5:05 PM Rome Tiburtina Bus Station 1:45 PM Prague Wilsonova Bus Station  Economy $147
  • Did you know that if you travel from Rome to Prague via Udine, you can save more than $43? You can find the corresponding connections below.
    • Itabus
      29h 46m
      0
      11:59 PM
      Rome
      Tiburtina Bus Station
      9:10 AM
      Udine
      Central Bus Station
      0
      Itabus
      Premium Economy
      $39
      • Waiting Time 9h 50m
    • FlixBus
      10h 45m
      0
      7:00 PM
      Udine
      Train Station
      4:45 AM
      Prague
      ÚAN Florenc
      0
      FlixBus
      Economy
      $47
    Travel time is 9h 6m longer, but you will save $43

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 22h 15m 7:30 AM Rome Tiburtina Bus Station 4:45 AM Prague ÚAN Florenc  Economy $117
FlixBus 24h 30m 11:05 PM Rome Tiburtina Bus Station 10:35 PM Prague Roztyly  Economy $123
FlixBus 22h 50m 11:05 PM Rome Tiburtina Bus Station 8:55 PM Prague ÚAN Florenc  Economy $125
FlixBus 23h 40m 12:20 PM Rome Tiburtina Bus Station 11:00 AM Prague Roztyly  Economy $135
FlixBus 24h 25m 1:05 PM Rome Anagnina Bus Station 12:30 PM Prague Roztyly  Economy $137
  • Did you know that if you travel from Rome to Prague via Udine, you can save more than $37? You can find the corresponding connections below.
    • Itabus
      20h 56m
      0
      11:59 PM
      Rome
      Tiburtina Bus Station
      9:10 AM
      Udine
      Train Station
      0
      Itabus
      Premium Economy
      $36
      • Waiting Time 1h 40m
    • FlixBus
      10h 5m
      0
      10:50 AM
      Udine
      Train Station
      8:55 PM
      Prague
      ÚAN Florenc
      0
      FlixBus
      Economy
      $44
    Travel Time is 0h 19m shorter, and you will save $37

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 22h 15m 7:30 AM Rome Tiburtina Bus Station 5:45 AM Prague ÚAN Florenc  Economy $111
FlixBus 25h 0m 12:20 PM Rome Tiburtina Bus Station 1:20 PM Prague Roztyly  Economy $116
FlixBus 25h 25m 12:20 PM Rome Tiburtina Bus Station 1:45 PM Prague Černý Most  Economy $117
FlixBus 23h 30m 11:05 PM Rome Tiburtina Bus Station 10:35 PM Prague Roztyly  Economy $121
FlixBus 21h 50m 11:05 PM Rome Tiburtina Bus Station 8:55 PM Prague ÚAN Florenc  Economy $125
  • Did you know that if you travel from Rome to Prague via Udine, you can save more than $32? You can find the corresponding connections below.
    • Itabus
      29h 46m
      0
      11:59 PM
      Rome
      Tiburtina Bus Station
      9:10 AM
      Udine
      Train Station
      0
      Itabus
      Premium Economy
      $36
      • Waiting Time 9h 50m
    • FlixBus
      10h 45m
      0
      7:00 PM
      Udine
      Train Station
      5:45 AM
      Prague
      ÚAN Florenc
      0
      FlixBus
      Economy
      $43
    Travel time is 7h 56m longer, but you will save $32

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 22h 15m 7:30 AM Rome Tiburtina Bus Station 5:45 AM Prague ÚAN Florenc  Economy $99
FlixBus 20h 50m 5:05 PM Rome Tiburtina Bus Station 1:55 PM Prague ÚAN Florenc  Economy $106
FlixBus 20h 40m 5:05 PM Rome Tiburtina Bus Station 1:45 PM Prague Wilsonova Bus Station  Economy $106
FlixBus 24h 25m 12:20 PM Rome Tiburtina Bus Station 12:45 PM Prague Na Knížecí Station  Economy $106
FlixBus 24h 10m 9:00 PM Rome Tiburtina Bus Station 9:10 PM Prague Na Knížecí Station  Economy $108
  • Did you know that if you travel from Rome to Prague via Udine, you can save more than $20? You can find the corresponding connections below.
    • Itabus
      20h 56m
      0
      11:59 PM
      Rome
      Tiburtina Bus Station
      9:10 AM
      Udine
      Central Bus Station
      0
      Itabus
      Premium Economy
      $34
      • Waiting Time 1h 40m
    • FlixBus
      10h 5m
      0
      10:50 AM
      Udine
      Train Station
      8:55 PM
      Prague
      ÚAN Florenc
      0
      FlixBus
      Economy
      $45
    Travel time is 0h 16m longer, but you will save $20

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 20h 40m 5:05 PM Rome Tiburtina Bus Station 1:45 PM Prague Wilsonova Bus Station  Economy $100
FlixBus 20h 50m 5:05 PM Rome Tiburtina Bus Station 1:55 PM Prague ÚAN Florenc  Economy $100
FlixBus 24h 25m 12:20 PM Rome Tiburtina Bus Station 12:45 PM Prague Na Knížecí Station  Economy $103
FlixBus 20h 30m 9:00 PM Rome Tiburtina Bus Station 5:30 PM Prague Wilsonova Bus Station  Economy $104
FlixBus 20h 45m 9:00 PM Rome Tiburtina Bus Station 5:45 PM Prague ÚAN Florenc  Economy $104
  • Did you know that if you travel from Rome to Prague via Udine, you can save more than $21? You can find the corresponding connections below.
    • Itabus
      20h 56m
      0
      11:59 PM
      Rome
      Tiburtina Bus Station
      9:10 AM
      Udine
      Central Bus Station
      0
      Itabus
      Premium Economy
      $34
      • Waiting Time 1h 40m
    • FlixBus
      10h 5m
      0
      10:50 AM
      Udine
      Train Station
      8:55 PM
      Prague
      ÚAN Florenc
      0
      FlixBus
      Economy
      $45
    Travel time is 0h 26m longer, but you will save $21

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 25h 25m 12:20 PM Rome Tiburtina Bus Station 1:45 PM Prague Černý Most  Economy $103
FlixBus 25h 0m 12:20 PM Rome Tiburtina Bus Station 1:20 PM Prague Roztyly  Economy $104
FlixBus 25h 45m 5:25 PM Rome Anagnina Bus Station 7:10 PM Prague Na Knížecí Station  Economy $106
FlixBus 21h 30m 9:30 AM Rome Tiburtina Bus Station 7:00 AM Prague Wilsonova Bus Station  Economy $107
FlixBus 24h 25m 12:20 PM Rome Tiburtina Bus Station 12:45 PM Prague Na Knížecí Station  Economy $107
  • Did you know that if you travel from Rome to Prague via Udine, you can save more than $24? You can find the corresponding connections below.
    • Itabus
      20h 56m
      0
      11:59 PM
      Rome
      Tiburtina Bus Station
      9:10 AM
      Udine
      Central Bus Station
      0
      Itabus
      Premium Economy
      $34
      • Waiting Time 1h 40m
    • FlixBus
      10h 5m
      0
      10:50 AM
      Udine
      Train Station
      8:55 PM
      Prague
      ÚAN Florenc
      0
      FlixBus
      Economy
      $45
    Travel Time is 0h 34m shorter, and you will save $24

Best Price Offer: The price for the cheapest bus from Rome to Prague is $76 on 11/10/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Rome and Prague

See here how frequent the connections between Rome and Prague are, during different times and days of the week.
Sunday is the busiest day, with more than 44 daily buses from Rome to Prague. Thursday has instead the fewest connections, with only 21 daily coaches between Rome and Prague.
The busiest time of the day is the Afternoon, with 127 buses from Rome to Prague, while Night sees the fewest connections between Rome and Prague, with 4 offers.

Facts about the bus from Rome to Prague

Compare all providers like FlixBus that travel 36 times every day by bus from Rome to Prague in one click! Book your bus ticket from Rome to Prague starting from $76!

Cheapest Bus $76
Fastest Bus 18h 35m
Earliest Bus 12:00 PM
Latest Bus 10:55 PM
Daily Bus Routes 36 Ø
Distance 572.5 miles
Bus Companies FlixBus

Cheapest bus connections from Rome to Prague

Every day, 36 buses from 1 bus companies leave Rome for Prague: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/22/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 10/18
Monday 10/19
Tuesday 10/20
Wednesday 10/21
Thursday 10/22
$149
Friday 10/23
$130
Saturday 10/24
$117
Sunday 10/25
$111
Monday 10/26
$99
Tuesday 10/27
$100
Wednesday 10/28
$103
Thursday 10/29
$107
Friday 10/30
$114
Saturday 10/31
$112
Sunday 11/01
$117
Monday 11/02
$94
Tuesday 11/03
$90
Wednesday 11/04
$83
Thursday 11/05
$88
Friday 11/06
$91
Saturday 11/07
$91
Sunday 11/08
$101
Monday 11/09
$87
Tuesday 11/10
$76
Wednesday 11/11
$85
Thursday 11/12
$81
Friday 11/13
$92
Saturday 11/14

The cheapest time to travel from Rome to Prague

See here on which day and which time of the day you can find the cheapest bus ticket from Rome to Prague, for the next 30 days.
With a price starting from $75, Tuesday is the cheapest day for a bus from Rome to Prague. Sunday instead is the most expensive day with prices starting from $93.
Night is the cheapest day time for bus tickets from Rome to Prague, with $75. Evening is the most expensive time of the day with prices starting from $104.

How to save money travelling from Rome to Prague

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Prague in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Prague, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Rome to Prague are also emptier.

Beloved bus companies from Rome to Prague

These are the most booked bus companies between Rome to Prague from our users.

FlixBus from Rome to Prague

FlixBus

Here you will find the key facts about the FlixBus bus route Rome to Prague:

Cheapest Price $99
Fastest Bus 18h 35m
Earliest Bus 12:00 PM
Last Bus 10:55 PM
Daily Connections 36 Ø
Found on 10/22/2026

All bus stations and stops in Rome and Prague

In the map below, you can see where to find all bus stations in Rome and Prague.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Rome to Prague? Compare all modes of transports from Rome to Prague.

Service and Comfort on the bus from Rome to Prague

Want to know which seat classes are available on the buses from Rome to Prague? Or which bus companies serve the route Rome to Prague? Below you will find answers to your questions.

FAQs about the Rome to Prague bus

How much does a Rome Prague bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $76 and takes 22h 15m to reach Prague. Compare offers to save money!

How much could I save by comparing buses from Rome to Prague?

This route is offered by 1 companies with a range of ticket prices between $76 and $225. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Prague.

On average, how many connections are available from Rome to Prague each day?

Every day, the Rome to Prague bus route is served by approximately 36 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Rome to Prague take?

The fastest bus from Rome to Prague is offered by FlixBus and takes 18h 35m. Bus tickets for this connection cost $140. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Rome to Prague?

The earliest bus arriving in Prague from Rome starts at 12:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Rome to Prague?

The latest bus trip departing from Rome for Prague starts at 10:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Rome Prague route?

When traveling by bus from Rome to Prague, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Rome and Prague?

You can check all the direct connections between Rome and Prague by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Rome to Prague bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Rome Prague bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Prague bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Prague on your planned travel date.

How does CheckMyBus find the best bus deals from Rome to Prague?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 36 daily trips between Rome and Prague. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Rome to Prague?

Prices and availability for 36 trips between Rome and Prague change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Rome to Prague

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Rome and to Prague

Here’s an overview of the most popular bus routes to Rome and to Prague. Simply click on the connection of your choice, and you will find all the details about your bus route!
From Scafati to Rome bus From Scafati to Rome bus
Nocera Inferiore to Rome bus Nocera Inferiore to Rome bus
Bus Potenza to Rome Bus Potenza to Rome
Buses Lanciano - Rome Buses Lanciano - Rome
Bus to Prague from Mykolaiv Bus to Prague from Mykolaiv
Lyon to Prague bus Lyon to Prague bus
Bus Kryvyi Rih to Prague Bus Kryvyi Rih to Prague
Buses to Prague from Teplice Buses to Prague from Teplice
Popular Airport Shuttles to Rome and to Prague
CheckMyBus › Buses in Italy › Bus to Rome › Bus to Prague

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