Bus from Rome to Prague from $102

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Compare all timetables for the bus from Rome to Prague

Here is a selection of the cheapest bus trips from the schedule from Rome to Prague from various bus operators like FlixBus for the next days.

today
$142
tomorrow
$126
Saturday
$150
Sunday
$142
Monday
$111
Tuesday
$102
Wednesday
$104

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 24h 25m 1:05 PM Rome Anagnina Bus Station 1:30 PM Prague Roztyly  Economy $142
FlixBus 20h 30m 9:00 PM Rome Tiburtina Bus Station 5:30 PM Prague Wilsonova Bus Station  Economy $143
FlixBus 20h 45m 9:00 PM Rome Tiburtina Bus Station 5:45 PM Prague ÚAN Florenc  Economy $143
FlixBus 20h 40m 5:05 PM Rome Tiburtina Bus Station 1:45 PM Prague Wilsonova Bus Station  Economy $150
FlixBus 20h 50m 5:05 PM Rome Tiburtina Bus Station 1:55 PM Prague ÚAN Florenc  Economy $150

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 20h 50m 5:05 PM Rome Tiburtina Bus Station 1:55 PM Prague ÚAN Florenc  Economy $126
FlixBus 20h 40m 5:05 PM Rome Tiburtina Bus Station 1:45 PM Prague Wilsonova Bus Station  Economy $126
FlixBus 22h 15m 7:30 AM Rome Tiburtina Bus Station 5:45 AM Prague ÚAN Florenc  Economy $137
FlixBus 20h 45m 9:00 PM Rome Tiburtina Bus Station 5:45 PM Prague ÚAN Florenc  Economy $146
FlixBus 20h 30m 9:00 PM Rome Tiburtina Bus Station 5:30 PM Prague Wilsonova Bus Station  Economy $146

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 20h 50m 5:05 PM Rome Tiburtina Bus Station 1:55 PM Prague ÚAN Florenc  Economy $150
FlixBus 20h 40m 5:05 PM Rome Tiburtina Bus Station 1:45 PM Prague Wilsonova Bus Station  Economy $150
FlixBus 23h 25m 12:20 PM Rome Tiburtina Bus Station 11:45 AM Prague Na Knížecí Station  Economy $157
FlixBus 20h 45m 9:00 PM Rome Tiburtina Bus Station 5:45 PM Prague ÚAN Florenc  Economy $162
FlixBus 20h 30m 9:00 PM Rome Tiburtina Bus Station 5:30 PM Prague Wilsonova Bus Station  Economy $162

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 20h 45m 9:00 PM Rome Tiburtina Bus Station 5:45 PM Prague ÚAN Florenc  Economy $142
FlixBus 20h 30m 9:00 PM Rome Tiburtina Bus Station 5:30 PM Prague Wilsonova Bus Station  Economy $142
FlixBus 22h 10m 9:00 PM Rome Tiburtina Bus Station 7:10 PM Prague Na Knížecí Station  Economy $151
FlixBus 27h 0m 5:00 PM Rome Tiburtina Bus Station 8:00 PM Prague Wilsonova Bus Station  Economy $157
FlixBus 24h 25m 1:05 PM Rome Anagnina Bus Station 1:30 PM Prague Roztyly  Economy $158
  • Did you know that if you travel from Rome to Prague via Udine, you can save more than $34? You can find the corresponding connections below.
    • FlixBus
      24h 25m
      0
      1:05 PM
      Rome
      Anagnina Bus Station
      11:40 PM
      Udine
      Train Station
      0
      FlixBus
      Economy
      $49
      • Waiting Time 0h 5m
    • FlixBus
      13h 45m
      0
      11:45 PM
      Udine
      Train Station
      1:30 PM
      Prague
      Roztyly
      0
      FlixBus
      Economy
      $60
    Travel time is 3h 55m longer, but you will save $34

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 20h 50m 5:05 PM Rome Tiburtina Bus Station 1:55 PM Prague ÚAN Florenc  Economy $111
FlixBus 20h 40m 5:05 PM Rome Tiburtina Bus Station 1:45 PM Prague Wilsonova Bus Station  Economy $111
FlixBus 20h 45m 9:00 PM Rome Tiburtina Bus Station 5:45 PM Prague ÚAN Florenc  Economy $127
FlixBus 20h 30m 9:00 PM Rome Tiburtina Bus Station 5:30 PM Prague Wilsonova Bus Station  Economy $127
FlixBus 22h 10m 9:00 PM Rome Tiburtina Bus Station 7:10 PM Prague Na Knížecí Station  Economy $127

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 20h 50m 5:05 PM Rome Tiburtina Bus Station 1:55 PM Prague ÚAN Florenc  Economy $102
FlixBus 20h 40m 5:05 PM Rome Tiburtina Bus Station 1:45 PM Prague Wilsonova Bus Station  Economy $102
FlixBus 22h 10m 9:00 PM Rome Tiburtina Bus Station 7:10 PM Prague Na Knížecí Station  Economy $121
FlixBus 22h 15m 7:30 AM Rome Tiburtina Bus Station 5:45 AM Prague ÚAN Florenc  Economy $122
FlixBus 20h 45m 9:00 PM Rome Tiburtina Bus Station 5:45 PM Prague ÚAN Florenc  Economy $122
  • Did you know that if you travel from Rome to Prague via Udine, you can save more than $23? You can find the corresponding connections below.
    • Itabus
      29h 46m
      0
      11:59 PM
      Rome
      Tiburtina Bus Station
      9:10 AM
      Udine
      Central Bus Station
      0
      Itabus
      Premium Economy
      $34
      • Waiting Time 9h 50m
    • FlixBus
      10h 45m
      0
      7:00 PM
      Udine
      Train Station
      5:45 AM
      Prague
      ÚAN Florenc
      0
      FlixBus
      Economy
      $45
    Travel time is 9h 6m longer, but you will save $23

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 20h 50m 5:05 PM Rome Tiburtina Bus Station 1:55 PM Prague ÚAN Florenc  Economy $104
FlixBus 20h 40m 5:05 PM Rome Tiburtina Bus Station 1:45 PM Prague Wilsonova Bus Station  Economy $104
FlixBus 22h 15m 7:30 AM Rome Tiburtina Bus Station 5:45 AM Prague ÚAN Florenc  Economy $119
FlixBus 20h 45m 9:00 PM Rome Tiburtina Bus Station 5:45 PM Prague ÚAN Florenc  Economy $120
FlixBus 20h 30m 9:00 PM Rome Tiburtina Bus Station 5:30 PM Prague Wilsonova Bus Station  Economy $120
  • Did you know that if you travel from Rome to Prague via Udine, you can save more than $25? You can find the corresponding connections below.
    • Itabus
      29h 46m
      0
      11:59 PM
      Rome
      Tiburtina Bus Station
      9:10 AM
      Udine
      Central Bus Station
      0
      Itabus
      Premium Economy
      $34
      • Waiting Time 9h 50m
    • FlixBus
      10h 45m
      0
      7:00 PM
      Udine
      Train Station
      5:45 AM
      Prague
      ÚAN Florenc
      0
      FlixBus
      Economy
      $45
    Travel time is 9h 16m longer, but you will save $25

Best Price Offer: The price for the cheapest bus from Rome to Prague is $102 on 7/28/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Rome and Prague

See here how frequent the connections between Rome and Prague are, during different times and days of the week.
Sunday is the busiest day, with more than 43 daily buses from Rome to Prague. Thursday has instead the fewest connections, with only 33 daily coaches between Rome and Prague.
The busiest time of the day is the Afternoon, with 152 buses from Rome to Prague, while Morning sees the fewest connections between Rome and Prague, with 35 offers.

Facts about the bus from Rome to Prague

Compare all providers like FlixBus that travel 38 times every day by bus from Rome to Prague in one click! Book your bus ticket from Rome to Prague starting from $102!

Cheapest Bus $102
Fastest Bus 19h 55m
Earliest Bus 12:00 PM
Latest Bus 11:50 PM
Daily Bus Routes 38 Ø
Distance 572.5 miles
Bus Companies FlixBus

Cheapest bus connections from Rome to Prague

Every day, 38 buses from 1 bus companies leave Rome for Prague: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/23/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 07/19
Monday 07/20
Tuesday 07/21
Wednesday 07/22
Thursday 07/23
$142
Friday 07/24
$126
Saturday 07/25
$150
Sunday 07/26
$142
Monday 07/27
$111
Tuesday 07/28
$102
Wednesday 07/29
$104
Thursday 07/30
$120
Friday 07/31
$125
Saturday 08/01
$121
Sunday 08/02
$137
Monday 08/03
$121
Tuesday 08/04
$114
Wednesday 08/05
$107
Thursday 08/06
$126
Friday 08/07
$133
Saturday 08/08
$126
Sunday 08/09
$129
Monday 08/10
$114
Tuesday 08/11
$114
Wednesday 08/12
$102
Thursday 08/13
$118
Friday 08/14
$102
Saturday 08/15

The cheapest time to travel from Rome to Prague

See here on which day and which time of the day you can find the cheapest bus ticket from Rome to Prague, for the next 30 days.
With a price starting from $102, Tuesday is the cheapest day for a bus from Rome to Prague. Sunday instead is the most expensive day with prices starting from $121.
Afternoon is the cheapest day time for bus tickets from Rome to Prague, with $102. Evening is the most expensive time of the day with prices starting from $120.

How to save money travelling from Rome to Prague

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Prague in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Prague, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Rome to Prague are also emptier.

All bus stations and stops in Rome and Prague

In the map below, you can see where to find all bus stations in Rome and Prague.

Service and Comfort on the bus from Rome to Prague

Want to know which seat classes are available on the buses from Rome to Prague? Or which bus companies serve the route Rome to Prague? Below you will find answers to your questions.

FAQs about the Rome to Prague bus

How much does a Rome Prague bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $102 and takes 20h 50m to reach Prague. Compare offers to save money!

How much could I save by comparing buses from Rome to Prague?

This route is offered by 1 companies with a range of ticket prices between $102 and $323. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Prague.

On average, how many connections are available from Rome to Prague each day?

Every day, the Rome to Prague bus route is served by approximately 38 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Rome to Prague take?

The fastest bus from Rome to Prague is offered by FlixBus and takes 19h 55m. Bus tickets for this connection cost $221. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Rome to Prague?

The earliest bus arriving in Prague from Rome starts at 12:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Rome to Prague?

The latest bus trip departing from Rome for Prague starts at 11:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Rome Prague route?

When traveling by bus from Rome to Prague, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Rome and Prague?

You can check all the direct connections between Rome and Prague by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Rome to Prague bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Rome Prague bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Prague bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Prague on your planned travel date.

How does CheckMyBus find the best bus deals from Rome to Prague?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 38 daily trips between Rome and Prague. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Rome to Prague?

Prices and availability for 38 trips between Rome and Prague change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Rome to Prague

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Rome and to Prague

Here’s an overview of the most popular bus routes to Rome and to Prague. Simply click on the connection of your choice, and you will find all the details about your bus route!
From Scafati to Rome bus From Scafati to Rome bus
Buses Ferrara - Rome Buses Ferrara - Rome
Buses Livorno - Rome Buses Livorno - Rome
Bus Ascoli Piceno to Rome Bus Ascoli Piceno to Rome
Bus Montpellier to Prague Bus Montpellier to Prague
Buses Verona to Prague Buses Verona to Prague
Bus Sumy to Prague Bus Sumy to Prague
Buses to Prague from Teplice Buses to Prague from Teplice
Popular Airport Shuttles to Rome and to Prague
CheckMyBus › Buses in Italy › Bus to Rome › Bus to Prague

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