Bus Phoenix, AZ to Knoxville, TN: Compare prices and save money

Compare all timetables for the bus from Phoenix, AZ to Knoxville, TN

Here is a selection of the cheapest bus trips from the schedule from Phoenix, AZ to Knoxville, TN from various bus operators like Greyhound US or FlixBus for the next days.

today

$122

tomorrow

$120

Tuesday

$135

Wednesday

$141

Thursday

$167

Friday

$174

Saturday

$163

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	39h 30m	4:10 AM	Phoenix, AZ	Bus Station	10:40 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$122	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/26/2026 4:10:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 7/27/2026 10:40:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 39h 30m
Greyhound US	55h 15m	9:35 AM	Phoenix, AZ	Bus Station	7:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$123	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/26/2026 9:35:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 7/28/2026 7:50:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 55h 15m
Greyhound US	44h 5m	10:45 PM	Phoenix, AZ	Bus Station	9:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$125	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/26/2026 10:45:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 7/28/2026 9:50:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 44h 5m
FlixBus	76h 25m	12:25 PM	Phoenix, AZ	44th St/Washington	7:50 PM	Knoxville, TN	Greyhound Bus Station	Economy	$137	A Bus from FlixBus goes from 44th St/Washington, Phoenix, AZ (USA) at 7/26/2026 12:25:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 7/29/2026 7:50:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 76h 25m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	55h 15m	9:35 AM	Phoenix, AZ	Bus Station	7:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$120	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/27/2026 9:35:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 7/29/2026 7:50:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 55h 15m
Greyhound US	57h 30m	7:20 AM	Phoenix, AZ	44th St/Washington	7:50 PM	Knoxville, TN	Greyhound Bus Station	Economy	$126	A Bus from Greyhound US goes from 44th St/Washington, Phoenix, AZ (USA) at 7/27/2026 7:20:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 7/29/2026 7:50:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 57h 30m
Greyhound US	39h 30m	4:10 AM	Phoenix, AZ	Bus Station	10:40 PM	Knoxville, TN	Greyhound Bus Station	Economy	$127	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/27/2026 4:10:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 7/28/2026 10:40:00 PM. 50 Economy ticket for $127 per person are available. Travel duration is 39h 30m
FlixBus	76h 25m	12:25 PM	Phoenix, AZ	44th St/Washington	7:50 PM	Knoxville, TN	Greyhound Bus Station	Economy	$132	A Bus from FlixBus goes from 44th St/Washington, Phoenix, AZ (USA) at 7/27/2026 12:25:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 7/30/2026 7:50:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 76h 25m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	55h 15m	9:35 AM	Phoenix, AZ	Bus Station	7:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$135	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/28/2026 9:35:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 7/30/2026 7:50:00 PM. 50 Economy ticket for $135 per person are available. Travel duration is 55h 15m
Greyhound US	44h 5m	10:45 PM	Phoenix, AZ	Bus Station	9:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$145	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/28/2026 10:45:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 7/30/2026 9:50:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 44h 5m
Greyhound US	39h 30m	4:10 AM	Phoenix, AZ	Bus Station	10:40 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$170	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/28/2026 4:10:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 7/29/2026 10:40:00 PM. 50 Economy ticket for $170 per person are available. Travel duration is 39h 30m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	44h 5m	10:45 PM	Phoenix, AZ	Bus Station	9:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$141	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/29/2026 10:45:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 7/31/2026 9:50:00 PM. 50 Economy ticket for $141 per person are available. Travel duration is 44h 5m
Greyhound US	55h 15m	9:35 AM	Phoenix, AZ	Bus Station	7:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$144	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/29/2026 9:35:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 7/31/2026 7:50:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 55h 15m
Greyhound US	39h 30m	4:10 AM	Phoenix, AZ	Bus Station	10:40 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$153	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/29/2026 4:10:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 7/30/2026 10:40:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 39h 30m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	55h 15m	9:35 AM	Phoenix, AZ	Bus Station	7:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$167	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/30/2026 9:35:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 8/1/2026 7:50:00 PM. 50 Economy ticket for $167 per person are available. Travel duration is 55h 15m
Greyhound US	57h 30m	7:20 AM	Phoenix, AZ	44th St/Washington	7:50 PM	Knoxville, TN	Greyhound Bus Station	Economy	$169	A Bus from Greyhound US goes from 44th St/Washington, Phoenix, AZ (USA) at 7/30/2026 7:20:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 8/1/2026 7:50:00 PM. 50 Economy ticket for $169 per person are available. Travel duration is 57h 30m
Greyhound US	44h 5m	10:45 PM	Phoenix, AZ	Bus Station	9:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$192	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/30/2026 10:45:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 8/1/2026 9:50:00 PM. 50 Economy ticket for $192 per person are available. Travel duration is 44h 5m
FlixBus	76h 25m	12:25 PM	Phoenix, AZ	44th St/Washington	7:50 PM	Knoxville, TN	Greyhound Bus Station	Economy	$200	A Bus from FlixBus goes from 44th St/Washington, Phoenix, AZ (USA) at 7/30/2026 12:25:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 8/2/2026 7:50:00 PM. 50 Economy ticket for $200 per person are available. Travel duration is 76h 25m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	39h 30m	4:10 AM	Phoenix, AZ	Bus Station	10:40 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$174	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/31/2026 4:10:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 8/1/2026 10:40:00 PM. 50 Economy ticket for $174 per person are available. Travel duration is 39h 30m
Greyhound US	55h 15m	9:35 AM	Phoenix, AZ	Bus Station	7:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$196	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/31/2026 9:35:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 8/2/2026 7:50:00 PM. 50 Economy ticket for $196 per person are available. Travel duration is 55h 15m
Greyhound US	44h 5m	10:45 PM	Phoenix, AZ	Bus Station	9:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$212	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 7/31/2026 10:45:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 8/2/2026 9:50:00 PM. 50 Economy ticket for $212 per person are available. Travel duration is 44h 5m

Did you know that if you travel from Phoenix, AZ to Knoxville, TN via Glendale, AZ, you can save more than $-22? You will find the corresponding connections below.
- 54h 45m
  
  Phoenix, AZ
  
  9 mi
  
  10:05 AM
  
  Glendale, AZ
  Central Bus Station
  
  7:50 PM
  
  Knoxville, TN
  Knoxville Area Transit Bus Stop
  
  0 mi
  
  Economy
  
  $196
  
  A Bus from goes from Central Bus Station, Glendale, AZ (USA) at 7/31/2026 10:05:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 8/2/2026 7:50:00 PM. 50 Economy ticket for $196 per person are available. Travel duration is 54h 45m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	39h 30m	4:10 AM	Phoenix, AZ	Bus Station	10:40 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$163	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 8/1/2026 4:10:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 8/2/2026 10:40:00 PM. 50 Economy ticket for $163 per person are available. Travel duration is 39h 30m
FlixBus	76h 25m	12:25 PM	Phoenix, AZ	44th St/Washington	7:50 PM	Knoxville, TN	Greyhound Bus Station	Economy	$165	A Bus from FlixBus goes from 44th St/Washington, Phoenix, AZ (USA) at 8/1/2026 12:25:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 8/4/2026 7:50:00 PM. 50 Economy ticket for $165 per person are available. Travel duration is 76h 25m
Greyhound US	55h 15m	9:35 AM	Phoenix, AZ	Bus Station	7:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$166	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 8/1/2026 9:35:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 8/3/2026 7:50:00 PM. 50 Economy ticket for $166 per person are available. Travel duration is 55h 15m
Greyhound US	57h 30m	7:20 AM	Phoenix, AZ	44th St/Washington	7:50 PM	Knoxville, TN	Greyhound Bus Station	Economy	$170	A Bus from Greyhound US goes from 44th St/Washington, Phoenix, AZ (USA) at 8/1/2026 7:20:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 8/3/2026 7:50:00 PM. 50 Economy ticket for $170 per person are available. Travel duration is 57h 30m

Best Price Offer: The price for the cheapest bus from Phoenix, AZ to Knoxville, TN is $120 on 7/27/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Phoenix, AZ and Knoxville, TN

See here how frequent the connections between Phoenix, AZ and Knoxville, TN are, during different times and days of the week.

Sunday is the busiest day, with more than 8 daily buses from Phoenix, AZ to Knoxville, TN. Tuesday has instead the fewest connections, with only 3 daily coaches between Phoenix, AZ and Knoxville, TN.

The busiest time of the day is the Morning, with 15 buses from Phoenix, AZ to Knoxville, TN, while Afternoon sees the fewest connections between Phoenix, AZ and Knoxville, TN, with 4 offers.

Facts about the bus from Phoenix, AZ to Knoxville, TN

Compare all providers like Greyhound US and FlixBus that travel 5 times every day by bus from Phoenix, AZ to Knoxville, TN in one click! Book your bus ticket from Phoenix, AZ to Knoxville, TN starting from $120!

Cheapest Bus	$120
Fastest Bus	42h 30m
Earliest Bus	4:10 AM
Latest Bus	10:45 PM
Daily Bus Routes	5 Ø
Distance	1,603.9 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Phoenix, AZ to Knoxville, TN

Every day, 5 buses from 2 bus companies leave Phoenix, AZ for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/26/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/26

$126

Monday 07/27

$120

Tuesday 07/28

$135

Wednesday 07/29

$141

Thursday 07/30

$167

Friday 07/31

$174

Saturday 08/01

$163

Sunday 08/02

$161

Monday 08/03

$157

Tuesday 08/04

$152

Wednesday 08/05

Thursday 08/06

$153

Friday 08/07

Saturday 08/08

$157

Sunday 08/09

$135

Monday 08/10

$127

Tuesday 08/11

$136

Wednesday 08/12

$180

Thursday 08/13

Friday 08/14

Saturday 08/15

$172

Sunday 08/16

$135

Monday 08/17

$141

Tuesday 08/18

$145

Wednesday 08/19

$146

Thursday 08/20

$149

Friday 08/21

$153

Saturday 08/22

The cheapest time to travel from Phoenix, AZ to Knoxville, TN

See here on which day and which time of the day you can find the cheapest bus ticket from Phoenix, AZ to Knoxville, TN, for the next 30 days.

With a price starting from $120, Monday is the cheapest day for a bus from Phoenix, AZ to Knoxville, TN. Saturday instead is the most expensive day with prices starting from $157.

Morning is the cheapest day time for bus tickets from Phoenix, AZ to Knoxville, TN, with $120. Afternoon is the most expensive time of the day with prices starting from $132.

How to save money travelling from Phoenix, AZ to Knoxville, TN

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Phoenix, AZ to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Phoenix, AZ to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Phoenix, AZ to Knoxville, TN are also emptier.

Beloved bus companies from Phoenix, AZ to Knoxville, TN

These are the most booked bus companies between Phoenix, AZ to Knoxville, TN from our users.

Greyhound US from Phoenix, AZ to Knoxville, TN

Here you will find the key facts about the Greyhound US bus route Phoenix, AZ to Knoxville, TN:

Cheapest Price	$120
Fastest Bus	42h 30m
Earliest Bus	4:10 AM
Last Bus	10:45 PM
Daily Connections	5 Ø
Found on	7/2/2026

All bus stations and stops in Phoenix, AZ and Knoxville, TN

In the map below, you can see where to find all bus stations in Phoenix, AZ and Knoxville, TN.

24th St & Jefferson St Station

24th St & Jefferson St

27th Av & McDowell Rd Bus Stop

N 27th Ave 1614

Bus Station

E Buckeye Rd 2115

44th St/Washington

Downtown

S 1st St 401S

Kingston Pike

Kingston Pike 6927

Walker Springs Plaza Shopping Center

Kingston Pike 8509

Knoxville Area Transit Bus Stop

Knoxville Area Transit Bus Stop Knoxville Area Transit Bus Stop

Greyhound Bus Station

E Magnolia Ave 100

Transit Center

E Church Ave 301

Service and Comfort on the bus from Phoenix, AZ to Knoxville, TN

Want to know which seat classes are available on the buses from Phoenix, AZ to Knoxville, TN? Or which bus companies serve the route Phoenix, AZ to Knoxville, TN? Below you will find answers to your questions.

FAQs about the Phoenix, AZ to Knoxville, TN bus

How much does a Phoenix, AZ Knoxville, TN bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $120 and takes 58h 15m to reach Knoxville, TN. Compare offers to save money!

How much could I save by comparing buses from Phoenix, AZ to Knoxville, TN?

This route is offered by 2 companies with a range of ticket prices between $120 and $212. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.

On average, how many connections are available from Phoenix, AZ to Knoxville, TN each day?

Every day, the Phoenix, AZ to Knoxville, TN bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Phoenix, AZ to Knoxville, TN take?

The fastest bus from Phoenix, AZ to Knoxville, TN is offered by Greyhound US and takes 42h 30m. Bus tickets for this connection cost $122. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Phoenix, AZ to Knoxville, TN?

The earliest bus arriving in Knoxville, TN from Phoenix, AZ starts at 4:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Phoenix, AZ to Knoxville, TN?

The latest bus trip departing from Phoenix, AZ for Knoxville, TN starts at 10:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Phoenix, AZ Knoxville, TN route?

When traveling by bus from Phoenix, AZ to Knoxville, TN, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Phoenix, AZ and Knoxville, TN?

You can check all the direct connections between Phoenix, AZ and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Phoenix, AZ to Knoxville, TN bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Phoenix, AZ Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Phoenix, AZ Knoxville, TN bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Phoenix, AZ to Knoxville, TN on your planned travel date.

How does CheckMyBus find the best bus deals from Phoenix, AZ to Knoxville, TN?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 5 daily trips between Phoenix, AZ and Knoxville, TN. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Phoenix, AZ to Knoxville, TN?

Prices and availability for 5 trips between Phoenix, AZ and Knoxville, TN change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Phoenix, AZ to Knoxville, TN

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Phoenix, AZ and to Knoxville, TN

Here’s an overview of the most popular bus routes to Phoenix, AZ and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!