Bus Perugia to Milan: Compare prices and save money

Compare all timetables for the bus from Perugia to Milan

Here is a selection of the cheapest bus trips from the schedule from Perugia to Milan from various bus operators like FlixBus, Itabus or Trenitalia for the next days.

today

$32

tomorrow

$48

Saturday

$32

Sunday

$48

Monday

$39

Tuesday

$39

Wednesday

$35

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	8h 15m	7:00 AM	Perugia	Piazza Partigiani Bus Station	3:15 PM	Milan	Lampugnano Bus Station	Economy	$32	A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 7/23/2026 7:00:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/23/2026 3:15:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 8h 15m
FlixBus	5h 45m	5:15 PM	Perugia	Piazza Partigiani Bus Station	11:00 PM	Milan	San Donato Bus Station	Economy	$35	A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 7/23/2026 5:15:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/23/2026 11:00:00 PM. 50 Economy ticket for $35 per person are available. Travel duration is 5h 45m
FlixBus	6h 20m	5:15 PM	Perugia	Piazza Partigiani Bus Station	11:35 PM	Milan	Lampugnano Bus Station	Economy	$35	A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 7/23/2026 5:15:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/23/2026 11:35:00 PM. 50 Economy ticket for $35 per person are available. Travel duration is 6h 20m
Itabus	6h 15m	11:25 PM	Perugia	Piazza Partigiani Bus Station	5:40 AM	Milan	Lampugnano Bus Station	Economy	$45	A Bus from Itabus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 7/23/2026 11:25:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/24/2026 5:40:00 AM. 50 Economy ticket for $45 per person are available. Travel duration is 6h 15m
Itabus	8h 10m	11:25 PM	Perugia	Bus Stop	7:35 AM	Milan	San Donato Bus Station	Premium Economy	$59	A Bus from Itabus goes from Bus Stop, Perugia (Italy) at 7/23/2026 11:25:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/24/2026 7:35:00 AM. 50 Premium Economy ticket for $59 per person are available. Travel duration is 8h 10m

Did you know that if you travel from Perugia to Milan via Florence, you can save more than $4? You can find the corresponding connections below.
- FlixBus
  
  7h 55m
  
  0
  
  10:55 AM
  
  Perugia
  Piazza Partigiani Bus Station
  
  1:35 PM
  
  Florence
  Villa Costanza Bus Station
  
  0
  
  Economy
  
  $15
  
  A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 7/24/2026 10:55:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 7/24/2026 1:35:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 2h 40m
- Itabus
  
  3h 55m
  
  0
  
  2:55 PM
  
  Florence
  Villa Costanza Bus Station
  
  6:50 PM
  
  Milan
  San Donato Bus Station
  
  0
  
  Premium Economy
  
  $13
  
  A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 7/24/2026 2:55:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/24/2026 6:50:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 3h 55m
Travel time is 2h 10m longer, but you will save $4

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	8h 15m	10:15 AM	Perugia	Bus Stop	6:30 PM	Milan	San Donato Bus Station	Economy	$48	A Bus from FlixBus goes from Bus Stop, Perugia (Italy) at 7/24/2026 10:15:00 AM to San Donato Bus Station, Milan (Italy) arriving at 7/24/2026 6:30:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 8h 15m
FlixBus	7h 40m	10:15 AM	Perugia	Bus Stop	5:55 PM	Milan	Lampugnano Bus Station	Economy	$52	A Bus from FlixBus goes from Bus Stop, Perugia (Italy) at 7/24/2026 10:15:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/24/2026 5:55:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 7h 40m
Itabus	6h 15m	11:25 PM	Perugia	Piazza Partigiani Bus Station	5:40 AM	Milan	Lampugnano Bus Station	Economy	$52	A Bus from Itabus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 7/24/2026 11:25:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/25/2026 5:40:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 6h 15m
FlixBus	8h 0m	9:55 AM	Perugia	Piazza Partigiani Bus Station	5:55 PM	Milan	Lampugnano Bus Station	Economy	$56	A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 7/24/2026 9:55:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/24/2026 5:55:00 PM. 50 Economy ticket for $56 per person are available. Travel duration is 8h 0m
Itabus	8h 45m	11:25 PM	Perugia	Bus Stop	8:10 AM	Milan	San Donato Bus Station	Premium Economy	$63	A Bus from Itabus goes from Bus Stop, Perugia (Italy) at 7/24/2026 11:25:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/25/2026 8:10:00 AM. 50 Premium Economy ticket for $63 per person are available. Travel duration is 8h 45m

Did you know that if you travel from Perugia to Milan via Pila, you can save more than $25? You will find the corresponding connections below.
- Save more than 52%
  
  2h 58m
  
  Perugia
  
  5 mi
  
  7:32 AM
  
  Pila
  Frazione Pilet
  
  10:30 AM
  
  Milan
  Lampugnano Bus Station
  
  0 mi
  
  Economy
  
  $23
  
  A Bus from goes from Frazione Pilet, Pila (Italy) at 7/24/2026 7:32:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/24/2026 10:30:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 2h 58m
Did you know that if you travel from Perugia to Milan via Florence, you can save more than $24? You can find the corresponding connections below.
- FlixBus
  
  9h 15m
  
  0
  
  11:25 AM
  
  Perugia
  Piazza Partigiani Bus Station
  
  1:35 PM
  
  Florence
  Villa Costanza Bus Station
  
  0
  
  Economy
  
  $13
  
  A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 7/25/2026 11:25:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 7/25/2026 1:35:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 2h 10m
- Itabus
  
  4h 20m
  
  0
  
  4:20 PM
  
  Florence
  Villa Costanza Bus Station
  
  8:40 PM
  
  Milan
  San Donato Bus Station
  
  0
  
  Premium Economy
  
  $11
  
  A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 7/25/2026 4:20:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/25/2026 8:40:00 PM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 4h 20m
Travel time is 3h 0m longer, but you will save $24

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	6h 15m	11:25 PM	Perugia	Piazza Partigiani Bus Station	5:40 AM	Milan	Lampugnano Bus Station	Economy	$32	A Bus from Itabus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 7/25/2026 11:25:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/26/2026 5:40:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 6h 15m
Itabus	8h 10m	11:25 PM	Perugia	Bus Stop	7:35 AM	Milan	San Donato Bus Station	Premium Economy	$38	A Bus from Itabus goes from Bus Stop, Perugia (Italy) at 7/25/2026 11:25:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/26/2026 7:35:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 8h 10m
FlixBus	5h 45m	5:15 PM	Perugia	Piazza Partigiani Bus Station	11:00 PM	Milan	San Donato Bus Station	Economy	$41	A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 7/25/2026 5:15:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/25/2026 11:00:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 5h 45m
FlixBus	6h 20m	5:15 PM	Perugia	Piazza Partigiani Bus Station	11:35 PM	Milan	Lampugnano Bus Station	Economy	$41	A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 7/25/2026 5:15:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/25/2026 11:35:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 6h 20m
FlixBus	7h 55m	11:25 AM	Perugia	Piazza Partigiani Bus Station	7:20 PM	Milan	Lampugnano Bus Station	Economy	$44	A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 7/25/2026 11:25:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/25/2026 7:20:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 7h 55m

Did you know that if you travel from Perugia to Milan via Florence, you can save more than $7? You can find the corresponding connections below.
- Itabus
  
  7h 0m
  
  0
  
  4:00 PM
  
  Perugia
  Bus Stop
  
  5:55 PM
  
  Florence
  Villa Costanza Bus Station
  
  0
  
  Economy
  
  $13
  
  A Bus from Itabus goes from Bus Stop, Perugia (Italy) at 7/25/2026 4:00:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 7/25/2026 5:55:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 1h 55m
- FlixBus
  
  3h 15m
  
  0
  
  7:45 PM
  
  Florence
  Villa Costanza Bus Station
  
  11:00 PM
  
  Milan
  San Donato Bus Station
  
  0
  
  Economy
  
  $12
  
  A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 7/25/2026 7:45:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/25/2026 11:00:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 3h 15m
Travel time is 1h 15m longer, but you will save $7

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 55m	11:25 AM	Perugia	Piazza Partigiani Bus Station	7:20 PM	Milan	Lampugnano Bus Station	Economy	$48	A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 7/26/2026 11:25:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/26/2026 7:20:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 7h 55m
Itabus	8h 10m	11:25 PM	Perugia	Bus Stop	7:35 AM	Milan	San Donato Bus Station	Premium Economy	$49	A Bus from Itabus goes from Bus Stop, Perugia (Italy) at 7/26/2026 11:25:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/27/2026 7:35:00 AM. 50 Premium Economy ticket for $49 per person are available. Travel duration is 8h 10m
Itabus	6h 15m	11:25 PM	Perugia	Piazza Partigiani Bus Station	5:40 AM	Milan	Lampugnano Bus Station	Economy	$52	A Bus from Itabus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 7/26/2026 11:25:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/27/2026 5:40:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 6h 15m
FlixBus	5h 45m	5:15 PM	Perugia	Piazza Partigiani Bus Station	11:00 PM	Milan	San Donato Bus Station	Economy	$54	A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 7/26/2026 5:15:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/26/2026 11:00:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 5h 45m
Trenitalia	8h 15m	2:45 PM	Perugia	Central Station	11:00 PM	Milan	Central Station - Piazza Luigi di Savoia	Economy	$57	A Bus from Trenitalia goes from Central Station, Perugia (Italy) at 7/26/2026 2:45:00 PM to Central Station - Piazza Luigi di Savoia, Milan (Italy) arriving at 7/26/2026 11:00:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 8h 15m

Did you know that if you travel from Perugia to Milan via Florence, you can save more than $26? You can find the corresponding connections below.
- FlixBus
  
  7h 5m
  
  0
  
  11:25 AM
  
  Perugia
  Piazza Partigiani Bus Station
  
  1:35 PM
  
  Florence
  Villa Costanza Bus Station
  
  0
  
  Economy
  
  $11
  
  A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 7/28/2026 11:25:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 7/28/2026 1:35:00 PM. 50 Economy ticket for $11 per person are available. Travel duration is 2h 10m
- FlixBus
  
  4h 10m
  
  0
  
  2:20 PM
  
  Florence
  Villa Costanza Bus Station
  
  6:30 PM
  
  Milan
  San Donato Bus Station
  
  0
  
  Economy
  
  $11
  
  A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 7/28/2026 2:20:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/28/2026 6:30:00 PM. 50 Economy ticket for $11 per person are available. Travel duration is 4h 10m
Travel time is 1h 20m longer, but you will save $26

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	6h 15m	11:25 PM	Perugia	Piazza Partigiani Bus Station	5:40 AM	Milan	Lampugnano Bus Station	Economy	$39	A Bus from Itabus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 7/27/2026 11:25:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/28/2026 5:40:00 AM. 50 Economy ticket for $39 per person are available. Travel duration is 6h 15m
FlixBus	7h 55m	11:25 AM	Perugia	Piazza Partigiani Bus Station	7:20 PM	Milan	Lampugnano Bus Station	Economy	$40	A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 7/27/2026 11:25:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/27/2026 7:20:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 7h 55m
FlixBus	8h 15m	10:15 AM	Perugia	Bus Stop	6:30 PM	Milan	San Donato Bus Station	Economy	$48	A Bus from FlixBus goes from Bus Stop, Perugia (Italy) at 7/27/2026 10:15:00 AM to San Donato Bus Station, Milan (Italy) arriving at 7/27/2026 6:30:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 8h 15m
FlixBus	7h 40m	10:15 AM	Perugia	Bus Stop	5:55 PM	Milan	Lampugnano Bus Station	Economy	$48	A Bus from FlixBus goes from Bus Stop, Perugia (Italy) at 7/27/2026 10:15:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/27/2026 5:55:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 7h 40m
Itabus	8h 10m	11:25 PM	Perugia	Bus Stop	7:35 AM	Milan	San Donato Bus Station	Premium Economy	$70	A Bus from Itabus goes from Bus Stop, Perugia (Italy) at 7/27/2026 11:25:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/28/2026 7:35:00 AM. 50 Premium Economy ticket for $70 per person are available. Travel duration is 8h 10m

Did you know that if you travel from Perugia to Milan via Florence, you can save more than $17? You can find the corresponding connections below.
- FlixBus
  
  7h 5m
  
  0
  
  11:25 AM
  
  Perugia
  Piazza Partigiani Bus Station
  
  1:35 PM
  
  Florence
  Villa Costanza Bus Station
  
  0
  
  Economy
  
  $11
  
  A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 7/28/2026 11:25:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 7/28/2026 1:35:00 PM. 50 Economy ticket for $11 per person are available. Travel duration is 2h 10m
- FlixBus
  
  4h 10m
  
  0
  
  2:20 PM
  
  Florence
  Villa Costanza Bus Station
  
  6:30 PM
  
  Milan
  San Donato Bus Station
  
  0
  
  Economy
  
  $11
  
  A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 7/28/2026 2:20:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/28/2026 6:30:00 PM. 50 Economy ticket for $11 per person are available. Travel duration is 4h 10m
Travel time is 0h 50m longer, but you will save $17

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	6h 15m	11:25 PM	Perugia	Piazza Partigiani Bus Station	5:40 AM	Milan	Lampugnano Bus Station	Economy	$39	A Bus from Itabus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 7/28/2026 11:25:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/29/2026 5:40:00 AM. 50 Economy ticket for $39 per person are available. Travel duration is 6h 15m
FlixBus	7h 55m	11:25 AM	Perugia	Piazza Partigiani Bus Station	7:20 PM	Milan	Lampugnano Bus Station	Economy	$40	A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 7/28/2026 11:25:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/28/2026 7:20:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 7h 55m
Itabus	8h 15m	11:25 PM	Perugia	Bus Stop	7:40 AM	Milan	San Donato Bus Station	Premium Economy	$42	A Bus from Itabus goes from Bus Stop, Perugia (Italy) at 7/28/2026 11:25:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/29/2026 7:40:00 AM. 50 Premium Economy ticket for $42 per person are available. Travel duration is 8h 15m
FlixBus	7h 40m	10:15 AM	Perugia	Bus Stop	5:55 PM	Milan	Lampugnano Bus Station	Economy	$43	A Bus from FlixBus goes from Bus Stop, Perugia (Italy) at 7/28/2026 10:15:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/28/2026 5:55:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 7h 40m
Itabus	8h 45m	11:25 PM	Perugia	Bus Stop	8:10 AM	Milan	San Donato Bus Station	Premium Economy	$44	A Bus from Itabus goes from Bus Stop, Perugia (Italy) at 7/28/2026 11:25:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/29/2026 8:10:00 AM. 50 Premium Economy ticket for $44 per person are available. Travel duration is 8h 45m

Did you know that if you travel from Perugia to Milan via Florence, you can save more than $17? You can find the corresponding connections below.
- FlixBus
  
  7h 5m
  
  0
  
  11:25 AM
  
  Perugia
  Piazza Partigiani Bus Station
  
  1:35 PM
  
  Florence
  Villa Costanza Bus Station
  
  0
  
  Economy
  
  $11
  
  A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 7/28/2026 11:25:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 7/28/2026 1:35:00 PM. 50 Economy ticket for $11 per person are available. Travel duration is 2h 10m
- FlixBus
  
  4h 10m
  
  0
  
  2:20 PM
  
  Florence
  Villa Costanza Bus Station
  
  6:30 PM
  
  Milan
  San Donato Bus Station
  
  0
  
  Economy
  
  $11
  
  A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 7/28/2026 2:20:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/28/2026 6:30:00 PM. 50 Economy ticket for $11 per person are available. Travel duration is 4h 10m
Travel time is 0h 50m longer, but you will save $17

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 55m	11:25 AM	Perugia	Piazza Partigiani Bus Station	7:20 PM	Milan	Lampugnano Bus Station	Economy	$35	A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 7/29/2026 11:25:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/29/2026 7:20:00 PM. 50 Economy ticket for $35 per person are available. Travel duration is 7h 55m
Itabus	6h 15m	11:25 PM	Perugia	Piazza Partigiani Bus Station	5:40 AM	Milan	Lampugnano Bus Station	Economy	$39	A Bus from Itabus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 7/29/2026 11:25:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 7/30/2026 5:40:00 AM. 50 Economy ticket for $39 per person are available. Travel duration is 6h 15m
FlixBus	7h 40m	10:15 AM	Perugia	Bus Stop	5:55 PM	Milan	Lampugnano Bus Station	Economy	$42	A Bus from FlixBus goes from Bus Stop, Perugia (Italy) at 7/29/2026 10:15:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 7/29/2026 5:55:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 7h 40m
FlixBus	8h 15m	10:15 AM	Perugia	Bus Stop	6:30 PM	Milan	San Donato Bus Station	Economy	$44	A Bus from FlixBus goes from Bus Stop, Perugia (Italy) at 7/29/2026 10:15:00 AM to San Donato Bus Station, Milan (Italy) arriving at 7/29/2026 6:30:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 8h 15m
Itabus	8h 15m	11:25 PM	Perugia	Bus Stop	7:40 AM	Milan	San Donato Bus Station	Premium Economy	$44	A Bus from Itabus goes from Bus Stop, Perugia (Italy) at 7/29/2026 11:25:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/30/2026 7:40:00 AM. 50 Premium Economy ticket for $44 per person are available. Travel duration is 8h 15m

Did you know that if you travel from Perugia to Milan via Florence, you can save more than $13? You can find the corresponding connections below.
- FlixBus
  
  7h 5m
  
  0
  
  11:25 AM
  
  Perugia
  Piazza Partigiani Bus Station
  
  1:35 PM
  
  Florence
  Villa Costanza Bus Station
  
  0
  
  Economy
  
  $11
  
  A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 7/28/2026 11:25:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 7/28/2026 1:35:00 PM. 50 Economy ticket for $11 per person are available. Travel duration is 2h 10m
- FlixBus
  
  4h 10m
  
  0
  
  2:20 PM
  
  Florence
  Villa Costanza Bus Station
  
  6:30 PM
  
  Milan
  San Donato Bus Station
  
  0
  
  Economy
  
  $11
  
  A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 7/28/2026 2:20:00 PM to San Donato Bus Station, Milan (Italy) arriving at 7/28/2026 6:30:00 PM. 50 Economy ticket for $11 per person are available. Travel duration is 4h 10m
Travel time is 0h 50m longer, but you will save $13

Best Price Offer: The price for the cheapest bus from Perugia to Milan is $25 on 8/5/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Perugia and Milan

See here how frequent the connections between Perugia and Milan are, during different times and days of the week.

Sunday is the busiest day, with more than 35 daily buses from Perugia to Milan. Wednesday has instead the fewest connections, with only 19 daily coaches between Perugia and Milan.

The busiest time of the day is the Evening, with 77 buses from Perugia to Milan, while Night sees the fewest connections between Perugia and Milan, with 14 offers.

Facts about the bus from Perugia to Milan

Compare all providers like FlixBus, Itabus and Trenitalia that travel 23 times every day by bus from Perugia to Milan in one click! Book your bus ticket from Perugia to Milan starting from $25!

Cheapest Bus	$25
Fastest Bus	4h 42m
Earliest Bus	2:05 AM
Latest Bus	11:25 PM
Daily Bus Routes	23 Ø
Distance	227.2 miles
Bus Companies	FlixBus, Itabus and Trenitalia

Cheapest bus connections from Perugia to Milan

Every day, 23 buses from 3 bus companies leave Perugia for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/23/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/19

Monday 07/20

Tuesday 07/21

Wednesday 07/22

Thursday 07/23

$47

Friday 07/24

$47

Saturday 07/25

$26

Sunday 07/26

$36

Monday 07/27

$35

Tuesday 07/28

$29

Wednesday 07/29

$32

Thursday 07/30

$26

Friday 07/31

$34

Saturday 08/01

$28

Sunday 08/02

$39

Monday 08/03

$36

Tuesday 08/04

$36

Wednesday 08/05

$25

Thursday 08/06

$26

Friday 08/07

$34

Saturday 08/08

$39

Sunday 08/09

$65

Monday 08/10

$38

Tuesday 08/11

$58

Wednesday 08/12

$52

Thursday 08/13

$39

Friday 08/14

$41

Saturday 08/15

The cheapest time to travel from Perugia to Milan

See here on which day and which time of the day you can find the cheapest bus ticket from Perugia to Milan, for the next 30 days.

With a price starting from $25, Wednesday is the cheapest day for a bus from Perugia to Milan. Sunday instead is the most expensive day with prices starting from $36.

Night is the cheapest day time for bus tickets from Perugia to Milan, with $25. Afternoon is the most expensive time of the day with prices starting from $35.

How to save money travelling from Perugia to Milan

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Perugia to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Perugia to Milan, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Perugia to Milan are also emptier.

Latest reviews for bus companies on the route Perugia - Milan

giancarlo , 3/27/2025

la durata della linea è eccessiva, sarebbe migliore se ci fosse una fermata intermedia durante il percorso per garantire un miglior servizio, sulla linea 539

All bus stations and stops in Perugia and Milan

In the map below, you can see where to find all bus stations in Perugia and Milan.

Piazza Partigiani Bus Station

Perugia-Autostazione Piazza Partigiani Perugia-Autostazione Piazza Partigiani

Bus Stop

Capolinea Bus Fontivegge (fronte stazione mini-metrò)

Piazza Italia

Piazza Italia 5-10

Universita' Train Station

Lampugnano Bus Station

Via Giulio Natta Lampugnano

Rogoredo Bus Station

Via Cassinis Giovanni Battista 76

San Donato Bus Station

Via Giuseppe Impastato 25

Duomo Bus Stop

Piazza del Duomo

Central Bus Station

Service and Comfort on the bus from Perugia to Milan

Want to know which seat classes are available on the buses from Perugia to Milan? Or which bus companies serve the route Perugia to Milan? Below you will find answers to your questions.

FAQs about the Perugia to Milan bus

How much does a Perugia Milan bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $25 and takes 6h 15m to reach Milan. Compare offers to save money!

How much could I save by comparing buses from Perugia to Milan?

This route is offered by 3 companies with a range of ticket prices between $25 and $149. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Milan.

On average, how many connections are available from Perugia to Milan each day?

Every day, the Perugia to Milan bus route is served by approximately 23 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Perugia to Milan take?

The fastest bus from Perugia to Milan is offered by Trenitalia and takes 4h 42m. Bus tickets for this connection cost $75. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Perugia to Milan?

The earliest bus arriving in Milan from Perugia starts at 2:05 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Perugia to Milan?

The latest bus trip departing from Perugia for Milan starts at 11:25 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Perugia Milan route?

When traveling by bus from Perugia to Milan, passengers can travel with FlixBus, Itabus and Trenitalia. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Perugia and Milan?

You can check all the direct connections between Perugia and Milan by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Itabus and Trenitalia.

What can I take with me on the Perugia to Milan bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Perugia Milan bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Perugia Milan bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Perugia to Milan on your planned travel date.

How does CheckMyBus find the best bus deals from Perugia to Milan?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 23 daily trips between Perugia and Milan. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Perugia to Milan?

Prices and availability for 23 trips between Perugia and Milan change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Perugia to Milan

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Perugia and to Milan

Here’s an overview of the most popular bus routes to Perugia and to Milan. Simply click on the connection of your choice, and you will find all the details about your bus route!