Bus Mississauga, ON to Buffalo, NY: Compare prices and save money

Compare all timetables for the bus from Mississauga, ON to Buffalo, NY

Here is a selection of the cheapest bus trips from the schedule from Mississauga, ON to Buffalo, NY from various bus operators like FlixBus for the next days.

today

$28

tomorrow

$28

Friday

$28

Saturday

$28

Sunday

$28

Monday

Tuesday

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	6h 5m	8:00 AM	Mississauga, ON	City Centre Dr / Duke of York Blvd	2:05 PM	Buffalo, NY	Central Bus Station		Economy	$28	A Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 9/9/2026 8:00:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 9/9/2026 2:05:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 6h 5m
	FlixBus	4h 55m	5:25 AM	Mississauga, ON	City Centre Dr / Duke of York Blvd	10:20 AM	Buffalo, NY	Central Bus Station		Economy	$41	A Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 9/9/2026 5:25:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 9/9/2026 10:20:00 AM. 50 Economy ticket for $41 per person are available. Travel duration is 4h 55m

Did you know that if you travel from Mississauga, ON to Buffalo, NY via Niagara Falls, ON, you can save more than $9? You can find the corresponding connections below.
- FlixBus
  
  4h 10m
  
  0
  
  6:10 AM
  
  Mississauga, ON
  City Centre Dr / Duke of York Blvd
  
  8:10 AM
  
  Niagara Falls, ON
  Table Rock Station
  
  0
  
  Economy
  
  $13
  
  A Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 9/11/2026 6:10:00 AM to Table Rock Station, Niagara Falls, ON (Canada) arriving at 9/11/2026 8:10:00 AM. 50 Economy ticket for $13 per person are available. Travel duration is 2h 0m
- FlixBus
  
  1h 35m
  
  0
  
  8:45 AM
  
  Niagara Falls, ON
  Rapidsview Bus Stop
  
  10:20 AM
  
  Buffalo, NY
  Central Bus Station
  
  0
  
  Economy
  
  $6
  
  A Bus from FlixBus goes from Rapidsview Bus Stop, Niagara Falls, ON (Canada) at 9/11/2026 8:45:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 9/11/2026 10:20:00 AM. 50 Economy ticket for $6 per person are available. Travel duration is 1h 35m
Travel Time is 0h 45m shorter, and you will save $9

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	4h 55m	5:25 AM	Mississauga, ON	City Centre Dr / Duke of York Blvd	10:20 AM	Buffalo, NY	Central Bus Station		Economy	$28	A Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 9/10/2026 5:25:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 9/10/2026 10:20:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 4h 55m
	FlixBus	5h 50m	4:55 PM	Mississauga, ON	City Centre Dr / Duke of York Blvd	10:45 PM	Buffalo, NY	Central Bus Station		Economy	$33	A Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 9/10/2026 4:55:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 9/10/2026 10:45:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 5h 50m

Did you know that if you travel from Mississauga, ON to Buffalo, NY via Niagara Falls, ON, you can save more than $10? You can find the corresponding connections below.
- FlixBus
  
  3h 25m
  
  0
  
  7:20 PM
  
  Mississauga, ON
  City Centre Dr / Duke of York Blvd
  
  9:00 PM
  
  Niagara Falls, ON
  Rapidsview Bus Stop
  
  0
  
  Economy
  
  $12
  
  A Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 9/11/2026 7:20:00 PM to Rapidsview Bus Stop, Niagara Falls, ON (Canada) arriving at 9/11/2026 9:00:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 1h 40m
- FlixBus
  
  1h 15m
  
  0
  
  9:30 PM
  
  Niagara Falls, ON
  Rapidsview Bus Stop
  
  10:45 PM
  
  Buffalo, NY
  Central Bus Station
  
  0
  
  Economy
  
  $6
  
  A Bus from FlixBus goes from Rapidsview Bus Stop, Niagara Falls, ON (Canada) at 9/11/2026 9:30:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 9/11/2026 10:45:00 PM. 50 Economy ticket for $6 per person are available. Travel duration is 1h 15m
Travel Time is 1h 30m shorter, and you will save $10

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	6h 5m	8:00 AM	Mississauga, ON	City Centre Dr / Duke of York Blvd	2:05 PM	Buffalo, NY	Central Bus Station	Economy	$28	A Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 9/11/2026 8:00:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 9/11/2026 2:05:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 6h 5m
FlixBus	5h 50m	4:55 PM	Mississauga, ON	City Centre Dr / Duke of York Blvd	10:45 PM	Buffalo, NY	Central Bus Station	Economy	$28	A Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 9/11/2026 4:55:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 9/11/2026 10:45:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 5h 50m
FlixBus	4h 55m	5:25 AM	Mississauga, ON	City Centre Dr / Duke of York Blvd	10:20 AM	Buffalo, NY	Central Bus Station	Economy	$42	A Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 9/11/2026 5:25:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 9/11/2026 10:20:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 4h 55m

Did you know that if you travel from Mississauga, ON to Buffalo, NY via Niagara Falls, ON, you can save more than $10? You can find the corresponding connections below.
- FlixBus
  
  3h 25m
  
  0
  
  7:20 PM
  
  Mississauga, ON
  City Centre Dr / Duke of York Blvd
  
  9:00 PM
  
  Niagara Falls, ON
  Rapidsview Bus Stop
  
  0
  
  Economy
  
  $12
  
  A Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 9/11/2026 7:20:00 PM to Rapidsview Bus Stop, Niagara Falls, ON (Canada) arriving at 9/11/2026 9:00:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 1h 40m
- FlixBus
  
  1h 15m
  
  0
  
  9:30 PM
  
  Niagara Falls, ON
  Rapidsview Bus Stop
  
  10:45 PM
  
  Buffalo, NY
  Central Bus Station
  
  0
  
  Economy
  
  $6
  
  A Bus from FlixBus goes from Rapidsview Bus Stop, Niagara Falls, ON (Canada) at 9/11/2026 9:30:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 9/11/2026 10:45:00 PM. 50 Economy ticket for $6 per person are available. Travel duration is 1h 15m
Travel Time is 1h 30m shorter, and you will save $10

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	6h 5m	8:00 AM	Mississauga, ON	City Centre Dr / Duke of York Blvd	2:05 PM	Buffalo, NY	Central Bus Station	Economy	$28	A Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 9/12/2026 8:00:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 9/12/2026 2:05:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 6h 5m
FlixBus	5h 50m	4:55 PM	Mississauga, ON	City Centre Dr / Duke of York Blvd	10:45 PM	Buffalo, NY	Central Bus Station	Economy	$28	A Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 9/12/2026 4:55:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 9/12/2026 10:45:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 5h 50m
FlixBus	4h 55m	5:25 AM	Mississauga, ON	City Centre Dr / Duke of York Blvd	10:20 AM	Buffalo, NY	Central Bus Station	Economy	$31	A Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 9/12/2026 5:25:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 9/12/2026 10:20:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 4h 55m

Did you know that if you travel from Mississauga, ON to Buffalo, NY via Niagara Falls, ON, you can save more than $11? You can find the corresponding connections below.
- FlixBus
  
  4h 10m
  
  0
  
  6:10 AM
  
  Mississauga, ON
  City Centre Dr / Duke of York Blvd
  
  8:10 AM
  
  Niagara Falls, ON
  Rapidsview Bus Stop
  
  0
  
  Economy
  
  $11
  
  A Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 9/14/2026 6:10:00 AM to Rapidsview Bus Stop, Niagara Falls, ON (Canada) arriving at 9/14/2026 8:10:00 AM. 50 Economy ticket for $11 per person are available. Travel duration is 2h 0m
- FlixBus
  
  1h 35m
  
  0
  
  8:45 AM
  
  Niagara Falls, ON
  Rapidsview Bus Stop
  
  10:20 AM
  
  Buffalo, NY
  Central Bus Station
  
  0
  
  Economy
  
  $6
  
  A Bus from FlixBus goes from Rapidsview Bus Stop, Niagara Falls, ON (Canada) at 9/14/2026 8:45:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 9/14/2026 10:20:00 AM. 50 Economy ticket for $6 per person are available. Travel duration is 1h 35m
Travel Time is 0h 45m shorter, and you will save $11

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	4h 55m	5:25 AM	Mississauga, ON	City Centre Dr / Duke of York Blvd	10:20 AM	Buffalo, NY	Central Bus Station	Economy	$28	A Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 9/13/2026 5:25:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 9/13/2026 10:20:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 4h 55m
FlixBus	6h 5m	8:00 AM	Mississauga, ON	City Centre Dr / Duke of York Blvd	2:05 PM	Buffalo, NY	Central Bus Station	Economy	$28	A Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 9/13/2026 8:00:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 9/13/2026 2:05:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 6h 5m
FlixBus	5h 50m	4:55 PM	Mississauga, ON	City Centre Dr / Duke of York Blvd	10:45 PM	Buffalo, NY	Central Bus Station	Economy	$46	A Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 9/13/2026 4:55:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 9/13/2026 10:45:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 50m

Did you know that if you travel from Mississauga, ON to Buffalo, NY via Niagara Falls, ON, you can save more than $11? You can find the corresponding connections below.
- FlixBus
  
  3h 25m
  
  0
  
  7:20 PM
  
  Mississauga, ON
  City Centre Dr / Duke of York Blvd
  
  9:00 PM
  
  Niagara Falls, ON
  Rapidsview Bus Stop
  
  0
  
  Economy
  
  $11
  
  A Bus from FlixBus goes from City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) at 9/14/2026 7:20:00 PM to Rapidsview Bus Stop, Niagara Falls, ON (Canada) arriving at 9/14/2026 9:00:00 PM. 50 Economy ticket for $11 per person are available. Travel duration is 1h 40m
- FlixBus
  
  1h 15m
  
  0
  
  9:30 PM
  
  Niagara Falls, ON
  Rapidsview Bus Stop
  
  10:45 PM
  
  Buffalo, NY
  Central Bus Station
  
  0
  
  Economy
  
  $6
  
  A Bus from FlixBus goes from Rapidsview Bus Stop, Niagara Falls, ON (Canada) at 9/14/2026 9:30:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 9/14/2026 10:45:00 PM. 50 Economy ticket for $6 per person are available. Travel duration is 1h 15m
Travel Time is 1h 30m shorter, and you will save $11

Best Price Offer: The price for the cheapest bus from Mississauga, ON to Buffalo, NY is $27 on 9/22/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Mississauga, ON and Buffalo, NY

See here how frequent the connections between Mississauga, ON and Buffalo, NY are, during different times and days of the week.

Sunday is the busiest day, with more than 3 daily buses from Mississauga, ON to Buffalo, NY. Wednesday has instead the fewest connections, with only 2 daily coaches between Mississauga, ON and Buffalo, NY.

The busiest time of the day is the Night, with 5 buses from Mississauga, ON to Buffalo, NY, while Morning sees the fewest connections between Mississauga, ON and Buffalo, NY, with 4 offers.

Facts about the bus from Mississauga, ON to Buffalo, NY

Compare all providers like FlixBus that travel 2 times every day by bus from Mississauga, ON to Buffalo, NY in one click! Book your bus ticket from Mississauga, ON to Buffalo, NY starting from $27!

Cheapest Bus	$27
Fastest Bus	4h 55m
Earliest Bus	5:25 AM
Latest Bus	4:55 PM
Daily Bus Routes	2 Ø
Distance	62.4 miles
Bus Companies	FlixBus

Cheapest bus connections from Mississauga, ON to Buffalo, NY

Every day, 2 buses from 1 bus companies leave Mississauga, ON for Buffalo, NY: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/09/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 09/06

Monday 09/07

Tuesday 09/08

Wednesday 09/09

$28

Thursday 09/10

$28

Friday 09/11

$28

Saturday 09/12

$28

Sunday 09/13

$28

Monday 09/14

Tuesday 09/15

Wednesday 09/16

$28

Thursday 09/17

Friday 09/18

Saturday 09/19

Sunday 09/20

Monday 09/21

$29

Tuesday 09/22

$27

Wednesday 09/23

Thursday 09/24

Friday 09/25

Saturday 09/26

Sunday 09/27

$27

Monday 09/28

$27

Tuesday 09/29

Wednesday 09/30

$27

Thursday 10/01

$29

Friday 10/02

$28

Saturday 10/03

The cheapest time to travel from Mississauga, ON to Buffalo, NY

See here on which day and which time of the day you can find the cheapest bus ticket from Mississauga, ON to Buffalo, NY, for the next 30 days.

With a price starting from $27, Wednesday is the cheapest day for a bus from Mississauga, ON to Buffalo, NY. Thursday instead is the most expensive day with prices starting from $28.

Night is the cheapest day time for bus tickets from Mississauga, ON to Buffalo, NY, with $27. Afternoon is the most expensive time of the day with prices starting from $28.

How to save money travelling from Mississauga, ON to Buffalo, NY

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mississauga, ON to Buffalo, NY in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mississauga, ON to Buffalo, NY, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mississauga, ON to Buffalo, NY are also emptier.

All bus stations and stops in Mississauga, ON and Buffalo, NY

In the map below, you can see where to find all bus stations in Mississauga, ON and Buffalo, NY.

City Centre Dr / Duke of York Blvd

Duke of York Blvd.

Mavis Rd At Cantay Rd Bus Stop

Mavis Rd At Cantay Rd Mavis Rd At Cantay Rd

Winston Churchill Bus Station

Mississauga (Winston Churchill) Mississauga (Winston Churchill)

Dundas St East

Dundas Street East 1050

Central Bus Station

Ellicott Street 181

Maple Road Gulf

Maple Rd 4641

Cleveland Hall

Asia Food Market

Niagara Falls Blvd 2055

Walden Galleria

Walden Galleria 1

Service and Comfort on the bus from Mississauga, ON to Buffalo, NY

Want to know which seat classes are available on the buses from Mississauga, ON to Buffalo, NY? Or which bus companies serve the route Mississauga, ON to Buffalo, NY? Below you will find answers to your questions.

FAQs about the Mississauga, ON to Buffalo, NY bus

How much does a Mississauga, ON Buffalo, NY bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $27 and takes 6h 5m to reach Buffalo, NY. Compare offers to save money!

How much could I save by comparing buses from Mississauga, ON to Buffalo, NY?

This route is offered by 1 companies with a range of ticket prices between $27 and $46. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Buffalo, NY.

On average, how many connections are available from Mississauga, ON to Buffalo, NY each day?

Every day, the Mississauga, ON to Buffalo, NY bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mississauga, ON to Buffalo, NY take?

The fastest bus from Mississauga, ON to Buffalo, NY is offered by FlixBus and takes 4h 55m. Bus tickets for this connection cost $41. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mississauga, ON to Buffalo, NY?

The earliest bus arriving in Buffalo, NY from Mississauga, ON starts at 5:25 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mississauga, ON to Buffalo, NY?

The latest bus trip departing from Mississauga, ON for Buffalo, NY starts at 4:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mississauga, ON Buffalo, NY route?

When traveling by bus from Mississauga, ON to Buffalo, NY, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mississauga, ON and Buffalo, NY?

You can check all the direct connections between Mississauga, ON and Buffalo, NY by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Mississauga, ON to Buffalo, NY bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mississauga, ON Buffalo, NY bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mississauga, ON Buffalo, NY bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mississauga, ON to Buffalo, NY on your planned travel date.

How does CheckMyBus find the best bus deals from Mississauga, ON to Buffalo, NY?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Mississauga, ON and Buffalo, NY. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Mississauga, ON to Buffalo, NY?

Prices and availability for 2 trips between Mississauga, ON and Buffalo, NY change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Mississauga, ON to Buffalo, NY

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mississauga, ON and to Buffalo, NY

Here’s an overview of the most popular bus routes to Mississauga, ON and to Buffalo, NY. Simply click on the connection of your choice, and you will find all the details about your bus route!