Bus Milwaukee to Greenville, SC: Compare prices and save money

Compare all timetables for the bus from Milwaukee to Greenville, SC

Here is a selection of the cheapest bus trips from the schedule from Milwaukee to Greenville, SC from various bus operators like Greyhound US, FlixBus or Tornado Bus Company for the next days.

today

tomorrow

Friday

Saturday

$92

Sunday

$88

Monday

$81

Tuesday

$73

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	23h 30m	6:30 AM	Milwaukee	Central Bus Station	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$92	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/12/2026 6:30:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 9/13/2026 7:00:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 23h 30m
FlixBus	24h 40m	9:00 AM	Milwaukee	Central Bus Station	10:40 AM	Greenville, SC	Woodruff Rd	Economy	$92	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 9/12/2026 9:00:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 9/13/2026 10:40:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 24h 40m
FlixBus	20h 15m	3:20 PM	Milwaukee	Central Bus Station	12:35 PM	Greenville, SC	Woodruff Rd	Economy	$92	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 9/12/2026 3:20:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 9/13/2026 12:35:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 20h 15m
Greyhound US	24h 0m	8:30 PM	Milwaukee	Central Bus Station	9:30 PM	Greenville, SC	Woodruff Rd	Economy	$93	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/12/2026 8:30:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 9/13/2026 9:30:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 24h 0m
Greyhound US	22h 50m	3:25 AM	Milwaukee	Central Bus Station	3:15 AM	Greenville, SC	Woodruff Rd	Economy	$172	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/12/2026 3:25:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 9/13/2026 3:15:00 AM. 50 Economy ticket for $172 per person are available. Travel duration is 22h 50m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	20h 15m	3:20 PM	Milwaukee	Central Bus Station	12:35 PM	Greenville, SC	Woodruff Rd	Economy	$88	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 9/13/2026 3:20:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 9/14/2026 12:35:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 20h 15m
FlixBus	24h 40m	9:00 AM	Milwaukee	Central Bus Station	10:40 AM	Greenville, SC	Woodruff Rd	Economy	$89	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 9/13/2026 9:00:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 9/14/2026 10:40:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 24h 40m
Greyhound US	22h 50m	3:25 AM	Milwaukee	Central Bus Station	3:15 AM	Greenville, SC	Woodruff Rd	Economy	$90	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/13/2026 3:25:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 9/14/2026 3:15:00 AM. 50 Economy ticket for $90 per person are available. Travel duration is 22h 50m
Greyhound US	23h 30m	6:30 AM	Milwaukee	Central Bus Station	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$98	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/13/2026 6:30:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 9/14/2026 7:00:00 AM. 50 Economy ticket for $98 per person are available. Travel duration is 23h 30m
Tornado Bus Company	49h 34m	9:30 AM	Milwaukee	S Cesar Chavez	12:04 PM	Greenville, SC	Guadalajara Supermarket	Economy	$370	A Bus from Tornado Bus Company goes from S Cesar Chavez, Milwaukee (USA) at 9/13/2026 9:30:00 AM to Guadalajara Supermarket, Greenville, SC (USA) arriving at 9/15/2026 12:04:00 PM. 50 Economy ticket for $370 per person are available. Travel duration is 49h 34m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	24h 40m	9:00 AM	Milwaukee	Central Bus Station	10:40 AM	Greenville, SC	Woodruff Rd	Economy	$81	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 9/14/2026 9:00:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 9/15/2026 10:40:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 24h 40m
Greyhound US	22h 50m	3:25 AM	Milwaukee	Central Bus Station	3:15 AM	Greenville, SC	Woodruff Rd	Economy	$83	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/14/2026 3:25:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 9/15/2026 3:15:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 22h 50m
Greyhound US	23h 30m	6:30 AM	Milwaukee	Central Bus Station	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$89	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/14/2026 6:30:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 9/15/2026 7:00:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 23h 30m
Tornado Bus Company	51h 10m	9:30 AM	Milwaukee	S Cesar Chavez	1:40 PM	Greenville, SC	Guadalajara Supermarket	Economy	$370	A Bus from Tornado Bus Company goes from S Cesar Chavez, Milwaukee (USA) at 9/14/2026 9:30:00 AM to Guadalajara Supermarket, Greenville, SC (USA) arriving at 9/16/2026 1:40:00 PM. 50 Economy ticket for $370 per person are available. Travel duration is 51h 10m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	24h 40m	9:00 AM	Milwaukee	Central Bus Station	10:40 AM	Greenville, SC	Woodruff Rd	Economy	$73	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 9/15/2026 9:00:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 9/16/2026 10:40:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 24h 40m
Greyhound US	22h 50m	3:25 AM	Milwaukee	Central Bus Station	3:15 AM	Greenville, SC	Woodruff Rd	Economy	$76	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/15/2026 3:25:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 9/16/2026 3:15:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 22h 50m
Greyhound US	23h 30m	6:30 AM	Milwaukee	Central Bus Station	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$78	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 9/15/2026 6:30:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 9/16/2026 7:00:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 23h 30m
Tornado Bus Company	51h 10m	9:30 AM	Milwaukee	S Cesar Chavez	1:40 PM	Greenville, SC	Guadalajara Supermarket	Economy	$370	A Bus from Tornado Bus Company goes from S Cesar Chavez, Milwaukee (USA) at 9/15/2026 9:30:00 AM to Guadalajara Supermarket, Greenville, SC (USA) arriving at 9/17/2026 1:40:00 PM. 50 Economy ticket for $370 per person are available. Travel duration is 51h 10m

Best Price Offer: The price for the cheapest bus from Milwaukee to Greenville, SC is $71 on 9/23/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Milwaukee and Greenville, SC

See here how frequent the connections between Milwaukee and Greenville, SC are, during different times and days of the week.

Tuesday is the busiest day, with more than 9 daily buses from Milwaukee to Greenville, SC. Monday has instead the fewest connections, with only 5 daily coaches between Milwaukee and Greenville, SC.

The busiest time of the day is the Morning, with 13 buses from Milwaukee to Greenville, SC, while Afternoon sees the fewest connections between Milwaukee and Greenville, SC, with 2 offers.

Facts about the bus from Milwaukee to Greenville, SC

Compare all providers like Greyhound US, FlixBus and Tornado Bus Company that travel 6 times every day by bus from Milwaukee to Greenville, SC in one click! Book your bus ticket from Milwaukee to Greenville, SC starting from $71!

Cheapest Bus	$71
Fastest Bus	21h 15m
Earliest Bus	3:25 AM
Latest Bus	8:30 PM
Daily Bus Routes	6 Ø
Distance	638.3 miles
Bus Companies	Greyhound US, FlixBus and Tornado Bus Company

Cheapest bus connections from Milwaukee to Greenville, SC

Every day, 6 buses from 3 bus companies leave Milwaukee for Greenville, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/09/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 09/06

Monday 09/07

Tuesday 09/08

Wednesday 09/09

Thursday 09/10

Friday 09/11

Saturday 09/12

$92

Sunday 09/13

$88

Monday 09/14

$81

Tuesday 09/15

$73

Wednesday 09/16

Thursday 09/17

$87

Friday 09/18

$79

Saturday 09/19

$88

Sunday 09/20

Monday 09/21

$81

Tuesday 09/22

Wednesday 09/23

$71

Thursday 09/24

Friday 09/25

$80

Saturday 09/26

$82

Sunday 09/27

Monday 09/28

$83

Tuesday 09/29

$79

Wednesday 09/30

Thursday 10/01

$83

Friday 10/02

$89

Saturday 10/03

The cheapest time to travel from Milwaukee to Greenville, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Milwaukee to Greenville, SC, for the next 30 days.

With a price starting from $73, Tuesday is the cheapest day for a bus from Milwaukee to Greenville, SC. Sunday instead is the most expensive day with prices starting from $88.

Night is the cheapest day time for bus tickets from Milwaukee to Greenville, SC, with $71. Evening is the most expensive time of the day with prices starting from $93.

How to save money travelling from Milwaukee to Greenville, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Milwaukee to Greenville, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Milwaukee to Greenville, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Milwaukee to Greenville, SC are also emptier.

Beloved bus companies from Milwaukee to Greenville, SC

These are the most booked bus companies between Milwaukee to Greenville, SC from our users.

Greyhound US from Milwaukee to Greenville, SC

Here you will find the key facts about the Greyhound US bus route Milwaukee to Greenville, SC:

Cheapest Price	$76
Fastest Bus	23h 50m
Earliest Bus	3:25 AM
Last Bus	8:30 PM
Daily Connections	3 Ø
Found on	8/16/2026

All bus stations and stops in Milwaukee and Greenville, SC

In the map below, you can see where to find all bus stations in Milwaukee and Greenville, SC.

Intermodal Station

W. St Paul's Ave 433

4960 S. 13th St. Park

Badger

N James Lovell St 635

S84 & Adler

S84 & Oconnor #6533

University

N Maryland Ave 3346

N Church St

Woodruff Rd

Woodruff Rd 1116

McDonald's

Woodruff Rd 1111

Greyhound Bus Station

Hendrix Dr 9

Guadalajara Supermarket

White Horse Rd 2803

Service and Comfort on the bus from Milwaukee to Greenville, SC

Want to know which seat classes are available on the buses from Milwaukee to Greenville, SC? Or which bus companies serve the route Milwaukee to Greenville, SC? Below you will find answers to your questions.

FAQs about the Milwaukee to Greenville, SC bus

How much does a Milwaukee Greenville, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $71 and takes 25h 40m to reach Greenville, SC. Compare offers to save money!

How much could I save by comparing buses from Milwaukee to Greenville, SC?

This route is offered by 3 companies with a range of ticket prices between $71 and $370. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Greenville, SC.

On average, how many connections are available from Milwaukee to Greenville, SC each day?

Every day, the Milwaukee to Greenville, SC bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Milwaukee to Greenville, SC take?

The fastest bus from Milwaukee to Greenville, SC is offered by FlixBus and takes 21h 15m. Bus tickets for this connection cost $92. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Milwaukee to Greenville, SC?

The earliest bus arriving in Greenville, SC from Milwaukee starts at 3:25 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Milwaukee to Greenville, SC?

The latest bus trip departing from Milwaukee for Greenville, SC starts at 8:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Milwaukee Greenville, SC route?

When traveling by bus from Milwaukee to Greenville, SC, passengers can travel with Greyhound US, FlixBus and Tornado Bus Company. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Milwaukee and Greenville, SC?

You can check all the direct connections between Milwaukee and Greenville, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US, FlixBus and Tornado Bus Company.

What can I take with me on the Milwaukee to Greenville, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Milwaukee Greenville, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Milwaukee Greenville, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Milwaukee to Greenville, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Milwaukee to Greenville, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Milwaukee and Greenville, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Milwaukee to Greenville, SC?

Prices and availability for 6 trips between Milwaukee and Greenville, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Milwaukee to Greenville, SC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Milwaukee and to Greenville, SC

Here’s an overview of the most popular bus routes to Milwaukee and to Greenville, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!