Bus Milton Keynes to Southampton - Compare all Companies

Compare all timetables for the bus from Milton Keynes to Southampton

Here is a selection of the cheapest bus trips from the schedule from Milton Keynes to Southampton from various bus operators like FlixBus for the next days.

today

$19

tomorrow

$21

Friday

$25

Saturday

$25

Sunday

$27

Monday

Tuesday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	5h 10m	8:20 AM	Milton Keynes	Central Station	1:30 PM	Southampton	Bus Station	Economy	$19	A Bus from FlixBus goes from Central Station, Milton Keynes (United Kingdom) at 10/21/2026 8:20:00 AM to Bus Station, Southampton (United Kingdom) arriving at 10/21/2026 1:30:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 5h 10m
FlixBus	4h 55m	1:20 PM	Milton Keynes	Central Station	6:15 PM	Southampton	Bus Station	Economy	$19	A Bus from FlixBus goes from Central Station, Milton Keynes (United Kingdom) at 10/21/2026 1:20:00 PM to Bus Station, Southampton (United Kingdom) arriving at 10/21/2026 6:15:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 4h 55m
FlixBus	4h 25m	7:20 PM	Milton Keynes	Central Station	11:45 PM	Southampton	Bus Station	Economy	$19	A Bus from FlixBus goes from Central Station, Milton Keynes (United Kingdom) at 10/21/2026 7:20:00 PM to Bus Station, Southampton (United Kingdom) arriving at 10/21/2026 11:45:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 4h 25m
FlixBus	4h 50m	8:20 AM	Milton Keynes	Central Station	1:10 PM	Southampton	University	Economy	$19	A Bus from FlixBus goes from Central Station, Milton Keynes (United Kingdom) at 10/21/2026 8:20:00 AM to University, Southampton (United Kingdom) arriving at 10/21/2026 1:10:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 4h 50m
FlixBus	4h 35m	1:20 PM	Milton Keynes	Central Station	5:55 PM	Southampton	University	Economy	$19	A Bus from FlixBus goes from Central Station, Milton Keynes (United Kingdom) at 10/21/2026 1:20:00 PM to University, Southampton (United Kingdom) arriving at 10/21/2026 5:55:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 4h 35m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	4h 25m	7:20 PM	Milton Keynes	Central Station	11:45 PM	Southampton	Bus Station	Economy	$21	A Bus from FlixBus goes from Central Station, Milton Keynes (United Kingdom) at 10/22/2026 7:20:00 PM to Bus Station, Southampton (United Kingdom) arriving at 10/22/2026 11:45:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 4h 25m
FlixBus	4h 5m	7:20 PM	Milton Keynes	Central Station	11:25 PM	Southampton	University	Economy	$21	A Bus from FlixBus goes from Central Station, Milton Keynes (United Kingdom) at 10/22/2026 7:20:00 PM to University, Southampton (United Kingdom) arriving at 10/22/2026 11:25:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 4h 5m
FlixBus	5h 10m	8:20 AM	Milton Keynes	Central Station	1:30 PM	Southampton	Bus Station	Economy	$28	A Bus from FlixBus goes from Central Station, Milton Keynes (United Kingdom) at 10/22/2026 8:20:00 AM to Bus Station, Southampton (United Kingdom) arriving at 10/22/2026 1:30:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 5h 10m
FlixBus	4h 50m	8:20 AM	Milton Keynes	Central Station	1:10 PM	Southampton	University	Economy	$28	A Bus from FlixBus goes from Central Station, Milton Keynes (United Kingdom) at 10/22/2026 8:20:00 AM to University, Southampton (United Kingdom) arriving at 10/22/2026 1:10:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 4h 50m

Did you know that if you travel from Milton Keynes to Southampton via London, you can save more than $4? You can find the corresponding connections below.
- National Express
  
  4h 20m
  
  0
  
  8:10 PM
  
  Milton Keynes
  Coachway
  
  9:45 PM
  
  London
  Victoria Coach Station
  
  0
  
  Economy
  
  $7
  
  A Bus from National Express goes from Coachway, Milton Keynes (United Kingdom) at 10/23/2026 8:10:00 PM to Victoria Coach Station, London (United Kingdom) arriving at 10/23/2026 9:45:00 PM. 50 Economy ticket for $7 per person are available. Travel duration is 1h 35m
- National Express
  
  2h 30m
  
  0
  
  10:00 PM
  
  London
  Victoria Coach Station
  
  12:30 AM
  
  Southampton
  Bus Station
  
  0
  
  Economy
  
  $9
  
  A Bus from National Express goes from Victoria Coach Station, London (United Kingdom) at 10/23/2026 10:00:00 PM to Bus Station, Southampton (United Kingdom) arriving at 10/24/2026 12:30:00 AM. 50 Economy ticket for $9 per person are available. Travel duration is 2h 30m
Travel time is 0h 15m longer, but you will save $4

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	4h 5m	7:20 PM	Milton Keynes	Central Station	11:25 PM	Southampton	University	Economy	$25	A Bus from FlixBus goes from Central Station, Milton Keynes (United Kingdom) at 10/23/2026 7:20:00 PM to University, Southampton (United Kingdom) arriving at 10/23/2026 11:25:00 PM. 50 Economy ticket for $25 per person are available. Travel duration is 4h 5m
FlixBus	4h 25m	7:20 PM	Milton Keynes	Central Station	11:45 PM	Southampton	Bus Station	Economy	$25	A Bus from FlixBus goes from Central Station, Milton Keynes (United Kingdom) at 10/23/2026 7:20:00 PM to Bus Station, Southampton (United Kingdom) arriving at 10/23/2026 11:45:00 PM. 50 Economy ticket for $25 per person are available. Travel duration is 4h 25m
FlixBus	4h 50m	8:20 AM	Milton Keynes	Central Station	1:10 PM	Southampton	University	Economy	$35	A Bus from FlixBus goes from Central Station, Milton Keynes (United Kingdom) at 10/23/2026 8:20:00 AM to University, Southampton (United Kingdom) arriving at 10/23/2026 1:10:00 PM. 50 Economy ticket for $35 per person are available. Travel duration is 4h 50m
FlixBus	5h 10m	8:20 AM	Milton Keynes	Central Station	1:30 PM	Southampton	Bus Station	Economy	$35	A Bus from FlixBus goes from Central Station, Milton Keynes (United Kingdom) at 10/23/2026 8:20:00 AM to Bus Station, Southampton (United Kingdom) arriving at 10/23/2026 1:30:00 PM. 50 Economy ticket for $35 per person are available. Travel duration is 5h 10m

Did you know that if you travel from Milton Keynes to Southampton via London, you can save more than $8? You can find the corresponding connections below.
- National Express
  
  4h 20m
  
  0
  
  8:10 PM
  
  Milton Keynes
  Coachway
  
  9:45 PM
  
  London
  Victoria Coach Station
  
  0
  
  Economy
  
  $7
  
  A Bus from National Express goes from Coachway, Milton Keynes (United Kingdom) at 10/23/2026 8:10:00 PM to Victoria Coach Station, London (United Kingdom) arriving at 10/23/2026 9:45:00 PM. 50 Economy ticket for $7 per person are available. Travel duration is 1h 35m
- National Express
  
  2h 30m
  
  0
  
  10:00 PM
  
  London
  Victoria Coach Station
  
  12:30 AM
  
  Southampton
  Bus Station
  
  0
  
  Economy
  
  $9
  
  A Bus from National Express goes from Victoria Coach Station, London (United Kingdom) at 10/23/2026 10:00:00 PM to Bus Station, Southampton (United Kingdom) arriving at 10/24/2026 12:30:00 AM. 50 Economy ticket for $9 per person are available. Travel duration is 2h 30m
Travel time is 0h 15m longer, but you will save $8

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	4h 55m	1:20 PM	Milton Keynes	Central Station	6:15 PM	Southampton	Bus Station	Economy	$25	A Bus from FlixBus goes from Central Station, Milton Keynes (United Kingdom) at 10/24/2026 1:20:00 PM to Bus Station, Southampton (United Kingdom) arriving at 10/24/2026 6:15:00 PM. 50 Economy ticket for $25 per person are available. Travel duration is 4h 55m
FlixBus	4h 25m	7:20 PM	Milton Keynes	Central Station	11:45 PM	Southampton	Bus Station	Economy	$25	A Bus from FlixBus goes from Central Station, Milton Keynes (United Kingdom) at 10/24/2026 7:20:00 PM to Bus Station, Southampton (United Kingdom) arriving at 10/24/2026 11:45:00 PM. 50 Economy ticket for $25 per person are available. Travel duration is 4h 25m
FlixBus	4h 35m	1:20 PM	Milton Keynes	Central Station	5:55 PM	Southampton	University	Economy	$26	A Bus from FlixBus goes from Central Station, Milton Keynes (United Kingdom) at 10/24/2026 1:20:00 PM to University, Southampton (United Kingdom) arriving at 10/24/2026 5:55:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 4h 35m
FlixBus	4h 5m	7:20 PM	Milton Keynes	Central Station	11:25 PM	Southampton	University	Economy	$26	A Bus from FlixBus goes from Central Station, Milton Keynes (United Kingdom) at 10/24/2026 7:20:00 PM to University, Southampton (United Kingdom) arriving at 10/24/2026 11:25:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 4h 5m
FlixBus	4h 10m	6:50 AM	Milton Keynes	Central Station	11:00 AM	Southampton	University	Economy	$31	A Bus from FlixBus goes from Central Station, Milton Keynes (United Kingdom) at 10/24/2026 6:50:00 AM to University, Southampton (United Kingdom) arriving at 10/24/2026 11:00:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 4h 10m

Did you know that if you travel from Milton Keynes to Southampton via London, you can save more than $9? You can find the corresponding connections below.
- National Express
  
  4h 45m
  
  0
  
  6:15 AM
  
  Milton Keynes
  Coachway
  
  8:20 AM
  
  London
  Victoria Coach Station
  
  0
  
  Economy
  
  $9
  
  A Bus from National Express goes from Coachway, Milton Keynes (United Kingdom) at 10/26/2026 6:15:00 AM to Victoria Coach Station, London (United Kingdom) arriving at 10/26/2026 8:20:00 AM. 50 Economy ticket for $9 per person are available. Travel duration is 2h 5m
- National Express
  
  2h 30m
  
  0
  
  8:30 AM
  
  London
  Victoria Coach Station
  
  11:00 AM
  
  Southampton
  University
  
  0
  
  Economy
  
  $7
  
  A Bus from National Express goes from Victoria Coach Station, London (United Kingdom) at 10/26/2026 8:30:00 AM to University, Southampton (United Kingdom) arriving at 10/26/2026 11:00:00 AM. 50 Economy ticket for $7 per person are available. Travel duration is 2h 30m
Travel time is 0h 40m longer, but you will save $9

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	4h 5m	7:20 PM	Milton Keynes	Central Station	11:25 PM	Southampton	University	Economy	$27	A Bus from FlixBus goes from Central Station, Milton Keynes (United Kingdom) at 10/25/2026 7:20:00 PM to University, Southampton (United Kingdom) arriving at 10/25/2026 11:25:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 4h 5m
FlixBus	4h 25m	7:20 PM	Milton Keynes	Central Station	11:45 PM	Southampton	Bus Station	Economy	$27	A Bus from FlixBus goes from Central Station, Milton Keynes (United Kingdom) at 10/25/2026 7:20:00 PM to Bus Station, Southampton (United Kingdom) arriving at 10/25/2026 11:45:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 4h 25m
FlixBus	4h 55m	1:20 PM	Milton Keynes	Central Station	6:15 PM	Southampton	Bus Station	Economy	$29	A Bus from FlixBus goes from Central Station, Milton Keynes (United Kingdom) at 10/25/2026 1:20:00 PM to Bus Station, Southampton (United Kingdom) arriving at 10/25/2026 6:15:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 4h 55m
FlixBus	4h 35m	1:20 PM	Milton Keynes	Central Station	5:55 PM	Southampton	University	Economy	$30	A Bus from FlixBus goes from Central Station, Milton Keynes (United Kingdom) at 10/25/2026 1:20:00 PM to University, Southampton (United Kingdom) arriving at 10/25/2026 5:55:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 4h 35m
FlixBus	4h 50m	8:20 AM	Milton Keynes	Central Station	1:10 PM	Southampton	University	Economy	$31	A Bus from FlixBus goes from Central Station, Milton Keynes (United Kingdom) at 10/25/2026 8:20:00 AM to University, Southampton (United Kingdom) arriving at 10/25/2026 1:10:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 4h 50m

Did you know that if you travel from Milton Keynes to Southampton via London, you can save more than $13? You can find the corresponding connections below.
- National Express
  
  3h 55m
  
  0
  
  9:05 PM
  
  Milton Keynes
  Coachway
  
  10:05 PM
  
  London
  Golders Green Coach Station
  
  0
  
  Economy
  
  $7
  
  A Bus from National Express goes from Coachway, Milton Keynes (United Kingdom) at 10/26/2026 9:05:00 PM to Golders Green Coach Station, London (United Kingdom) arriving at 10/26/2026 10:05:00 PM. 50 Economy ticket for $7 per person are available. Travel duration is 1h 0m
- National Express
  
  2h 30m
  
  0
  
  10:30 PM
  
  London
  Victoria Coach Station
  
  1:00 AM
  
  Southampton
  Bus Station
  
  0
  
  Economy
  
  $7
  
  A Bus from National Express goes from Victoria Coach Station, London (United Kingdom) at 10/26/2026 10:30:00 PM to Bus Station, Southampton (United Kingdom) arriving at 10/27/2026 1:00:00 AM. 50 Economy ticket for $7 per person are available. Travel duration is 2h 30m
Travel Time is 0h 10m shorter, and you will save $13

Best Price Offer: The price for the cheapest bus from Milton Keynes to Southampton is $19 on 10/21/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Milton Keynes and Southampton

See here how frequent the connections between Milton Keynes and Southampton are, during different times and days of the week.

Sunday is the busiest day, with more than 8 daily buses from Milton Keynes to Southampton. Thursday has instead the fewest connections, with only 4 daily coaches between Milton Keynes and Southampton.

The busiest time of the day is the Morning, with 14 buses from Milton Keynes to Southampton, while Afternoon sees the fewest connections between Milton Keynes and Southampton, with 6 offers.

Facts about the bus from Milton Keynes to Southampton

Compare all providers like FlixBus that travel 6 times every day by bus from Milton Keynes to Southampton in one click! Book your bus ticket from Milton Keynes to Southampton starting from $19!

Cheapest Bus	$19
Fastest Bus	4h 5m
Earliest Bus	8:20 AM
Latest Bus	7:20 PM
Daily Bus Routes	6 Ø
Distance	82.9 miles
Bus Companies	FlixBus

Cheapest bus connections from Milton Keynes to Southampton

Every day, 6 buses from 1 bus companies leave Milton Keynes for Southampton: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/21/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 10/18

Monday 10/19

Tuesday 10/20

Wednesday 10/21

$19

Thursday 10/22

$21

Friday 10/23

$25

Saturday 10/24

$25

Sunday 10/25

$27

Monday 10/26

Tuesday 10/27

Wednesday 10/28

Thursday 10/29

Friday 10/30

$24

Saturday 10/31

$23

Sunday 11/01

Monday 11/02

Tuesday 11/03

Wednesday 11/04

Thursday 11/05

Friday 11/06

Saturday 11/07

Sunday 11/08

$22

Monday 11/09

Tuesday 11/10

Wednesday 11/11

$19

Thursday 11/12

$19

Friday 11/13

Saturday 11/14

The cheapest time to travel from Milton Keynes to Southampton

See here on which day and which time of the day you can find the cheapest bus ticket from Milton Keynes to Southampton, for the next 30 days.

With a price starting from $19, Wednesday is the cheapest day for a bus from Milton Keynes to Southampton. Friday instead is the most expensive day with prices starting from $24.

Afternoon is the cheapest day time for bus tickets from Milton Keynes to Southampton, with $19. Morning is the most expensive time of the day with prices starting from $19.

How to save money travelling from Milton Keynes to Southampton

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Milton Keynes to Southampton in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Milton Keynes to Southampton, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Milton Keynes to Southampton are also emptier.

All bus stations and stops in Milton Keynes and Southampton

In the map below, you can see where to find all bus stations in Milton Keynes and Southampton.

Coachway

The Coachway

Central Station

Bus Stop

Midsummer Boulevard 653

National Bowl

Kingston Shopping Centre

Winchester Cir 1

Bus Station

Harbour Parade 2

Solent University

East Park Terrace

University

Highfield Interchange Highfield Interchange

New Road

Port

Town Quay

Service and Comfort on the bus from Milton Keynes to Southampton

Want to know which seat classes are available on the buses from Milton Keynes to Southampton? Or which bus companies serve the route Milton Keynes to Southampton? Below you will find answers to your questions.

FAQs about the Milton Keynes to Southampton bus

How much does a Milton Keynes Southampton bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $19 and takes 4h 55m to reach Southampton. Compare offers to save money!

How much could I save by comparing buses from Milton Keynes to Southampton?

This route is offered by 1 companies with a range of ticket prices between $19 and $35. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Southampton.

On average, how many connections are available from Milton Keynes to Southampton each day?

Every day, the Milton Keynes to Southampton bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Milton Keynes to Southampton take?

The fastest bus from Milton Keynes to Southampton is offered by FlixBus and takes 4h 5m. Bus tickets for this connection cost $19. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Milton Keynes to Southampton?

The earliest bus arriving in Southampton from Milton Keynes starts at 8:20 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Milton Keynes to Southampton?

The latest bus trip departing from Milton Keynes for Southampton starts at 7:20 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Milton Keynes Southampton route?

When traveling by bus from Milton Keynes to Southampton, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Milton Keynes and Southampton?

You can check all the direct connections between Milton Keynes and Southampton by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Milton Keynes to Southampton bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Milton Keynes Southampton bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Milton Keynes Southampton bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Milton Keynes to Southampton on your planned travel date.

How does CheckMyBus find the best bus deals from Milton Keynes to Southampton?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Milton Keynes and Southampton. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Milton Keynes to Southampton?

Prices and availability for 6 trips between Milton Keynes and Southampton change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Milton Keynes to Southampton

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Milton Keynes and to Southampton

Here’s an overview of the most popular bus routes to Milton Keynes and to Southampton. Simply click on the connection of your choice, and you will find all the details about your bus route!