Compare all timetables for the bus from Milan to Palermo
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 21h 55m | 1:05 PM | Milan | Lampugnano Bus Station | 11:00 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $59 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/7/2026 1:05:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/8/2026 11:00:00 AM. 50 Economy ticket for $59 per person are available. Travel duration is 21h 55m
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| FlixBus | 24h 30m | 2:45 PM | Milan | San Donato Bus Station | 3:15 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $74 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 9/7/2026 2:45:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/8/2026 3:15:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 24h 30m
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| FlixBus | 22h 15m | 12:45 PM | Milan | San Donato Bus Station | 11:00 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $75 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 9/7/2026 12:45:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/8/2026 11:00:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 22h 15m
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| Autoservizi Salemi | 21h 0m | 10:45 AM | Milan | San Donato Bus Station | 7:45 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $102 |
A Bus from Autoservizi Salemi goes from San Donato Bus Station, Milan (Italy) at 9/7/2026 10:45:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/8/2026 7:45:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 21h 0m
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| Autoservizi Salemi | 21h 45m | 10:00 AM | Milan | Lampugnano Bus Station | 7:45 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $106 |
A Bus from Autoservizi Salemi goes from Lampugnano Bus Station, Milan (Italy) at 9/7/2026 10:00:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/8/2026 7:45:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 21h 45m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 21h 50m | 5:25 PM | Milan | San Donato Bus Station | 3:15 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $63 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 9/8/2026 5:25:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/9/2026 3:15:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 21h 50m
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| FlixBus | 21h 55m | 1:05 PM | Milan | Lampugnano Bus Station | 11:00 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $63 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/8/2026 1:05:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/9/2026 11:00:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 21h 55m
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| FlixBus | 22h 35m | 4:40 PM | Milan | Lampugnano Bus Station | 3:15 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $63 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/8/2026 4:40:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/9/2026 3:15:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 22h 35m
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| FlixBus | 26h 10m | 8:50 AM | Milan | San Donato Bus Station | 11:00 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $74 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 9/8/2026 8:50:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/9/2026 11:00:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 26h 10m
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| FlixBus | 24h 50m | 6:30 PM | Milan | San Donato Bus Station | 7:20 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $74 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 9/8/2026 6:30:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/9/2026 7:20:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 24h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 21h 55m | 1:05 PM | Milan | Lampugnano Bus Station | 11:00 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $57 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/9/2026 1:05:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/10/2026 11:00:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 21h 55m
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| FlixBus | 22h 15m | 12:45 PM | Milan | San Donato Bus Station | 11:00 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $59 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 9/9/2026 12:45:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/10/2026 11:00:00 AM. 50 Economy ticket for $59 per person are available. Travel duration is 22h 15m
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| FlixBus | 24h 50m | 6:30 PM | Milan | San Donato Bus Station | 7:20 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $69 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 9/9/2026 6:30:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/10/2026 7:20:00 PM. 50 Economy ticket for $69 per person are available. Travel duration is 24h 50m
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| Autoservizi Salemi | 21h 45m | 10:00 AM | Milan | Lampugnano Bus Station | 7:45 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $102 |
A Bus from Autoservizi Salemi goes from Lampugnano Bus Station, Milan (Italy) at 9/9/2026 10:00:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/10/2026 7:45:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 21h 45m
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| Autoservizi Salemi | 21h 0m | 10:45 AM | Milan | San Donato Bus Station | 7:45 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $102 |
A Bus from Autoservizi Salemi goes from San Donato Bus Station, Milan (Italy) at 9/9/2026 10:45:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/10/2026 7:45:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 21h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 24h 50m | 6:30 PM | Milan | San Donato Bus Station | 7:20 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $56 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 9/10/2026 6:30:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/11/2026 7:20:00 PM. 50 Economy ticket for $56 per person are available. Travel duration is 24h 50m
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| FlixBus | 22h 35m | 4:40 PM | Milan | Lampugnano Bus Station | 3:15 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $56 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/10/2026 4:40:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/11/2026 3:15:00 PM. 50 Economy ticket for $56 per person are available. Travel duration is 22h 35m
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| FlixBus | 25h 35m | 5:45 PM | Milan | Lampugnano Bus Station | 7:20 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $56 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/10/2026 5:45:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/11/2026 7:20:00 PM. 50 Economy ticket for $56 per person are available. Travel duration is 25h 35m
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| FlixBus | 25h 20m | 9:40 AM | Milan | San Donato Bus Station | 11:00 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $57 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 9/10/2026 9:40:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/11/2026 11:00:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 25h 20m
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| FlixBus | 21h 50m | 5:25 PM | Milan | San Donato Bus Station | 3:15 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $57 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 9/10/2026 5:25:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/11/2026 3:15:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 21h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 24h 50m | 6:30 PM | Milan | San Donato Bus Station | 7:20 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $60 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 9/11/2026 6:30:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/12/2026 7:20:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 24h 50m
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| FlixBus | 25h 35m | 5:45 PM | Milan | Lampugnano Bus Station | 7:20 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $60 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/11/2026 5:45:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/12/2026 7:20:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 25h 35m
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| FlixBus | 22h 15m | 12:45 PM | Milan | San Donato Bus Station | 11:00 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $62 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 9/11/2026 12:45:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/12/2026 11:00:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 22h 15m
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| Autoservizi Salemi | 21h 0m | 10:45 AM | Milan | San Donato Bus Station | 7:45 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $102 |
A Bus from Autoservizi Salemi goes from San Donato Bus Station, Milan (Italy) at 9/11/2026 10:45:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/12/2026 7:45:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 21h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 24h 50m | 6:30 PM | Milan | San Donato Bus Station | 7:20 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $63 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 9/12/2026 6:30:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/13/2026 7:20:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 24h 50m
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| FlixBus | 21h 55m | 1:05 PM | Milan | Lampugnano Bus Station | 11:00 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $64 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/12/2026 1:05:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/13/2026 11:00:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 21h 55m
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| FlixBus | 25h 35m | 5:45 PM | Milan | Lampugnano Bus Station | 7:20 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $64 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/12/2026 5:45:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/13/2026 7:20:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 25h 35m
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| FlixBus | 22h 35m | 4:40 PM | Milan | Lampugnano Bus Station | 3:15 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $67 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/12/2026 4:40:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/13/2026 3:15:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 22h 35m
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| FlixBus | 21h 50m | 5:25 PM | Milan | San Donato Bus Station | 3:15 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $68 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 9/12/2026 5:25:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/13/2026 3:15:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 21h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 25h 35m | 5:45 PM | Milan | Lampugnano Bus Station | 7:20 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $75 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/13/2026 5:45:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/14/2026 7:20:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 25h 35m
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| FlixBus | 24h 50m | 6:30 PM | Milan | San Donato Bus Station | 7:20 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $77 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 9/13/2026 6:30:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/14/2026 7:20:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 24h 50m
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| FlixBus | 21h 50m | 5:25 PM | Milan | San Donato Bus Station | 3:15 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $88 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 9/13/2026 5:25:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/14/2026 3:15:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 21h 50m
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| FlixBus | 22h 35m | 4:40 PM | Milan | Lampugnano Bus Station | 3:15 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $88 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 9/13/2026 4:40:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/14/2026 3:15:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 22h 35m
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| FlixBus | 25h 0m | 10:00 AM | Milan | San Donato Bus Station | 11:00 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $91 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 9/13/2026 10:00:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/14/2026 11:00:00 AM. 50 Economy ticket for $91 per person are available. Travel duration is 25h 0m
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FlixBus23h 10mMilan5 mi4:05 PMAssagoMilanofiori Forum3:15 PMPalermoVia Tommaso Fazello Bus Stop0 miEconomyA Bus from FlixBus goes from Milanofiori Forum, Assago (Italy) at 9/13/2026 4:05:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/14/2026 3:15:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 23h 10m
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Best Price Offer: The price for the cheapest bus from Milan to Palermo is $37 on 9/28/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Milan and Palermo
Facts about the bus from Milan to Palermo
Compare all providers like FlixBus and Autoservizi Salemi that travel 8 times every day by bus from Milan to Palermo in one click! Book your bus ticket from Milan to Palermo starting from $37!
| Cheapest Bus | $37 |
| Fastest Bus | 21h 0m |
| Earliest Bus | 10:00 AM |
| Latest Bus | 6:30 PM |
| Daily Bus Routes | 8 Ø |
| Distance | 551.5 miles |
| Bus Companies | FlixBus and Autoservizi Salemi |
Cheapest bus connections from Milan to Palermo
Every day, 8 buses from 2 bus companies leave Milan for Palermo: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/07/2026 and for the following days.
The cheapest time to travel from Milan to Palermo
How to save money travelling from Milan to Palermo
Book the ticket from Milan to Palermo in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Milan to Palermo, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Milan to Palermo are also emptier.All bus stations and stops in Milan and Palermo
In the map below, you can see where to find all bus stations in Milan and Palermo.
Service and Comfort on the bus from Milan to Palermo
FAQs about the Milan to Palermo bus
How much does a Milan Palermo bus trip cost?
How much could I save by comparing buses from Milan to Palermo?
On average, how many connections are available from Milan to Palermo each day?
How long does a bus journey from Milan to Palermo take?
What time is the first bus from Milan to Palermo?
What time is the last bus from Milan to Palermo?
Which bus companies operate the Milan Palermo route?
Is there a direct bus between Milan and Palermo?
What can I take with me on the Milan to Palermo bus route?
What equipment is available for the Milan Palermo bus route?
How does CheckMyBus find the best bus deals from Milan to Palermo?
How does CheckMyBus technology work for trips from Milan to Palermo?
Available seat classes which are offered on the bus route Milan to Palermo
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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