Compare all timetables for the bus from Milan to Palermo
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 22h 10m | 1:05 PM | Milan | Lampugnano Bus Station | 11:15 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $138 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/23/2026 1:05:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/24/2026 11:15:00 AM. 50 Economy ticket for $138 per person are available. Travel duration is 22h 10m
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| FlixBus | 21h 55m | 1:05 PM | Milan | Lampugnano Bus Station | 11:00 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $182 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/23/2026 1:05:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/24/2026 11:00:00 AM. 50 Economy ticket for $182 per person are available. Travel duration is 21h 55m
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| FlixBus | 21h 50m | 5:25 PM | Milan | San Donato Bus Station | 3:15 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $196 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 7/23/2026 5:25:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/24/2026 3:15:00 PM. 50 Economy ticket for $196 per person are available. Travel duration is 21h 50m
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| FlixBus | 22h 35m | 4:40 PM | Milan | Lampugnano Bus Station | 3:15 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $200 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/23/2026 4:40:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/24/2026 3:15:00 PM. 50 Economy ticket for $200 per person are available. Travel duration is 22h 35m
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| FlixBus | 25h 35m | 5:45 PM | Milan | Lampugnano Bus Station | 7:20 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $225 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/23/2026 5:45:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/24/2026 7:20:00 PM. 50 Economy ticket for $225 per person are available. Travel duration is 25h 35m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 22h 10m | 1:05 PM | Milan | Lampugnano Bus Station | 11:15 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $100 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/24/2026 1:05:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/25/2026 11:15:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 22h 10m
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| FlixBus | 22h 35m | 4:40 PM | Milan | Lampugnano Bus Station | 3:15 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $158 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/24/2026 4:40:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/25/2026 3:15:00 PM. 50 Economy ticket for $158 per person are available. Travel duration is 22h 35m
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| FlixBus | 21h 50m | 5:25 PM | Milan | San Donato Bus Station | 3:15 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $159 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 7/24/2026 5:25:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/25/2026 3:15:00 PM. 50 Economy ticket for $159 per person are available. Travel duration is 21h 50m
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| FlixBus | 21h 55m | 1:05 PM | Milan | Lampugnano Bus Station | 11:00 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $182 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/24/2026 1:05:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/25/2026 11:00:00 AM. 50 Economy ticket for $182 per person are available. Travel duration is 21h 55m
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| FlixBus | 24h 50m | 6:30 PM | Milan | San Donato Bus Station | 7:20 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $200 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 7/24/2026 6:30:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/25/2026 7:20:00 PM. 50 Economy ticket for $200 per person are available. Travel duration is 24h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 22h 10m | 1:05 PM | Milan | Lampugnano Bus Station | 11:15 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $121 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/25/2026 1:05:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/26/2026 11:15:00 AM. 50 Economy ticket for $121 per person are available. Travel duration is 22h 10m
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| FlixBus | 22h 35m | 4:40 PM | Milan | Lampugnano Bus Station | 3:15 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $155 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/25/2026 4:40:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/26/2026 3:15:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 22h 35m
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| FlixBus | 21h 50m | 5:25 PM | Milan | San Donato Bus Station | 3:15 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $157 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 7/25/2026 5:25:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/26/2026 3:15:00 PM. 50 Economy ticket for $157 per person are available. Travel duration is 21h 50m
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| FlixBus | 21h 55m | 1:05 PM | Milan | Lampugnano Bus Station | 11:00 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $182 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/25/2026 1:05:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/26/2026 11:00:00 AM. 50 Economy ticket for $182 per person are available. Travel duration is 21h 55m
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| FlixBus | 25h 35m | 5:45 PM | Milan | Lampugnano Bus Station | 7:20 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $194 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/25/2026 5:45:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/26/2026 7:20:00 PM. 50 Economy ticket for $194 per person are available. Travel duration is 25h 35m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 22h 10m | 1:05 PM | Milan | Lampugnano Bus Station | 11:15 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $138 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/26/2026 1:05:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/27/2026 11:15:00 AM. 50 Economy ticket for $138 per person are available. Travel duration is 22h 10m
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| FlixBus | 21h 50m | 5:25 PM | Milan | San Donato Bus Station | 3:15 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $154 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 7/26/2026 5:25:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/27/2026 3:15:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 21h 50m
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| FlixBus | 22h 35m | 4:40 PM | Milan | Lampugnano Bus Station | 3:15 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $157 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/26/2026 4:40:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/27/2026 3:15:00 PM. 50 Economy ticket for $157 per person are available. Travel duration is 22h 35m
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| FlixBus | 21h 55m | 1:05 PM | Milan | Lampugnano Bus Station | 11:00 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $182 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/26/2026 1:05:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/27/2026 11:00:00 AM. 50 Economy ticket for $182 per person are available. Travel duration is 21h 55m
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| FlixBus | 22h 15m | 12:45 PM | Milan | San Donato Bus Station | 11:00 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $219 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 7/26/2026 12:45:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/27/2026 11:00:00 AM. 50 Economy ticket for $219 per person are available. Travel duration is 22h 15m
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FlixBus30h 55m012:25 PMMilanLampugnano Bus Station6:15 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/27/2026 12:25:00 PM to Train Station, Siena (Italy) arriving at 7/27/2026 6:15:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 5h 50m
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FlixBus20h 55m010:25 PMSienaTrain Station7:20 PMPalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 7/27/2026 10:25:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/28/2026 7:20:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 20h 55m
Waiting Time 4h 10m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Autoservizi Salemi | 21h 45m | 10:00 AM | Milan | Lampugnano Bus Station | 7:45 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $101 |
A Bus from Autoservizi Salemi goes from Lampugnano Bus Station, Milan (Italy) at 7/27/2026 10:00:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/28/2026 7:45:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 21h 45m
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| Autoservizi Salemi | 21h 0m | 10:45 AM | Milan | San Donato Bus Station | 7:45 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $103 |
A Bus from Autoservizi Salemi goes from San Donato Bus Station, Milan (Italy) at 7/27/2026 10:45:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/28/2026 7:45:00 AM. 50 Economy ticket for $103 per person are available. Travel duration is 21h 0m
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| FlixBus | 21h 55m | 1:05 PM | Milan | Lampugnano Bus Station | 11:00 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $115 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/27/2026 1:05:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/28/2026 11:00:00 AM. 50 Economy ticket for $115 per person are available. Travel duration is 21h 55m
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| FlixBus | 22h 10m | 1:05 PM | Milan | Lampugnano Bus Station | 11:15 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $143 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/27/2026 1:05:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/28/2026 11:15:00 AM. 50 Economy ticket for $143 per person are available. Travel duration is 22h 10m
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| FlixBus | 24h 30m | 2:45 PM | Milan | San Donato Bus Station | 3:15 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $147 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 7/27/2026 2:45:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/28/2026 3:15:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 24h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 24h 10m | 3:05 PM | Milan | Lampugnano Bus Station | 3:15 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $122 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/28/2026 3:05:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/29/2026 3:15:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 24h 10m
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| FlixBus | 21h 55m | 1:05 PM | Milan | Lampugnano Bus Station | 11:00 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $130 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/28/2026 1:05:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/29/2026 11:00:00 AM. 50 Economy ticket for $130 per person are available. Travel duration is 21h 55m
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| FlixBus | 22h 10m | 1:05 PM | Milan | Lampugnano Bus Station | 11:15 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $147 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/28/2026 1:05:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/29/2026 11:15:00 AM. 50 Economy ticket for $147 per person are available. Travel duration is 22h 10m
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| FlixBus | 22h 15m | 12:45 PM | Milan | San Donato Bus Station | 11:00 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $160 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 7/28/2026 12:45:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/29/2026 11:00:00 AM. 50 Economy ticket for $160 per person are available. Travel duration is 22h 15m
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| FlixBus | 24h 50m | 6:30 PM | Milan | San Donato Bus Station | 7:20 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $174 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 7/28/2026 6:30:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/29/2026 7:20:00 PM. 50 Economy ticket for $174 per person are available. Travel duration is 24h 50m
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Itabus24h 20m010:40 AMMilanLampugnano Bus Station4:20 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 7/29/2026 10:40:00 AM to Train Station, Siena (Italy) arriving at 7/29/2026 4:20:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 5h 40m
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FlixBus16h 0m07:00 PMSienaTrain Station11:00 AMPalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 7/29/2026 7:00:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/30/2026 11:00:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 16h 0m
Waiting Time 2h 40m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Autoservizi Salemi | 21h 45m | 10:00 AM | Milan | Lampugnano Bus Station | 7:45 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $101 |
A Bus from Autoservizi Salemi goes from Lampugnano Bus Station, Milan (Italy) at 7/29/2026 10:00:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/30/2026 7:45:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 21h 45m
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| Autoservizi Salemi | 21h 0m | 10:45 AM | Milan | San Donato Bus Station | 7:45 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $101 |
A Bus from Autoservizi Salemi goes from San Donato Bus Station, Milan (Italy) at 7/29/2026 10:45:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/30/2026 7:45:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 21h 0m
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| FlixBus | 21h 55m | 1:05 PM | Milan | Lampugnano Bus Station | 11:00 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $135 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/29/2026 1:05:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/30/2026 11:00:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 21h 55m
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| FlixBus | 24h 0m | 3:15 PM | Milan | Lampugnano Bus Station | 3:15 PM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $138 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/29/2026 3:15:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/30/2026 3:15:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 24h 0m
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| FlixBus | 22h 10m | 1:05 PM | Milan | Lampugnano Bus Station | 11:15 AM | Palermo | Via Tommaso Fazello Bus Stop | Economy | $142 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 7/29/2026 1:05:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/30/2026 11:15:00 AM. 50 Economy ticket for $142 per person are available. Travel duration is 22h 10m
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Itabus24h 20m010:40 AMMilanLampugnano Bus Station4:20 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 7/29/2026 10:40:00 AM to Train Station, Siena (Italy) arriving at 7/29/2026 4:20:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 5h 40m
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FlixBus16h 0m07:00 PMSienaTrain Station11:00 AMPalermoVia Tommaso Fazello Bus Stop0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 7/29/2026 7:00:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 7/30/2026 11:00:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 16h 0m
Waiting Time 2h 40m -
Best Price Offer: The price for the cheapest bus from Milan to Palermo is $100 on 7/24/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Milan and Palermo
Facts about the bus from Milan to Palermo
Compare all providers like FlixBus and Autoservizi Salemi that travel 7 times every day by bus from Milan to Palermo in one click! Book your bus ticket from Milan to Palermo starting from $100!
| Cheapest Bus | $100 |
| Fastest Bus | 21h 0m |
| Earliest Bus | 1:05 PM |
| Latest Bus | 6:30 PM |
| Daily Bus Routes | 7 Ø |
| Distance | 551.5 miles |
| Bus Companies | FlixBus and Autoservizi Salemi |
Cheapest bus connections from Milan to Palermo
Every day, 7 buses from 2 bus companies leave Milan for Palermo: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/23/2026 and for the following days.
The cheapest time to travel from Milan to Palermo
How to save money travelling from Milan to Palermo
Book the ticket from Milan to Palermo in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Milan to Palermo, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Milan to Palermo are also emptier.All bus stations and stops in Milan and Palermo
In the map below, you can see where to find all bus stations in Milan and Palermo.
Service and Comfort on the bus from Milan to Palermo
FAQs about the Milan to Palermo bus
How much does a Milan Palermo bus trip cost?
How much could I save by comparing buses from Milan to Palermo?
On average, how many connections are available from Milan to Palermo each day?
How long does a bus journey from Milan to Palermo take?
What time is the first bus from Milan to Palermo?
What time is the last bus from Milan to Palermo?
Which bus companies operate the Milan Palermo route?
Is there a direct bus between Milan and Palermo?
What can I take with me on the Milan to Palermo bus route?
What equipment is available for the Milan Palermo bus route?
How does CheckMyBus find the best bus deals from Milan to Palermo?
How does CheckMyBus technology work for trips from Milan to Palermo?
Available seat classes which are offered on the bus route Milan to Palermo
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Milan and to Palermo
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