Compare all timetables for the bus from Lyon to Prague
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlaBlaCar Bus | 18h 50m | 2:55 PM | Lyon | Perrache Train Station | 9:45 AM | Prague | ÚAN Florenc | Economy | $91 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/24/2026 2:55:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 7/25/2026 9:45:00 AM. 50 Economy ticket for $91 per person are available. Travel duration is 18h 50m
|
||
| FlixBus | 16h 30m | 5:20 AM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 9:50 PM | Prague | ÚAN Florenc | Economy | $94 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/24/2026 5:20:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 7/24/2026 9:50:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 16h 30m
|
||
| FlixBus | 17h 25m | 10:00 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 3:25 PM | Prague | ÚAN Florenc | Economy | $99 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/24/2026 10:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 7/25/2026 3:25:00 PM. 50 Economy ticket for $99 per person are available. Travel duration is 17h 25m
|
||
| FlixBus | 18h 10m | 10:00 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 4:10 PM | Prague | Černý Most | Economy | $99 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/24/2026 10:00:00 PM to Černý Most, Prague (Czech Republic) arriving at 7/25/2026 4:10:00 PM. 50 Economy ticket for $99 per person are available. Travel duration is 18h 10m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 25m | 10:00 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 3:25 PM | Prague | ÚAN Florenc | Economy | $90 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/25/2026 10:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 7/26/2026 3:25:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 17h 25m
|
||
| FlixBus | 18h 10m | 10:00 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 4:10 PM | Prague | Černý Most | Economy | $90 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/25/2026 10:00:00 PM to Černý Most, Prague (Czech Republic) arriving at 7/26/2026 4:10:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 18h 10m
|
||
| FlixBus | 16h 30m | 5:20 AM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 9:50 PM | Prague | ÚAN Florenc | Economy | $94 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/25/2026 5:20:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 7/25/2026 9:50:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 16h 30m
|
||
| FlixBus | 19h 25m | 5:20 AM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 12:45 AM | Prague | Wilsonova Bus Station | Economy | $109 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/25/2026 5:20:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 7/26/2026 12:45:00 AM. 50 Economy ticket for $109 per person are available. Travel duration is 19h 25m
|
||
| FlixBus | 18h 45m | 3:30 AM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 10:15 PM | Prague | Wilsonova Bus Station | Economy | $110 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/25/2026 3:30:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 7/25/2026 10:15:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 18h 45m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 16h 30m | 5:20 AM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 9:50 PM | Prague | ÚAN Florenc | Economy | $90 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/26/2026 5:20:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 7/26/2026 9:50:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 16h 30m
|
||
| FlixBus | 17h 25m | 10:00 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 3:25 PM | Prague | ÚAN Florenc | Economy | $94 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/26/2026 10:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 7/27/2026 3:25:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 17h 25m
|
||
| FlixBus | 18h 10m | 10:00 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 4:10 PM | Prague | Černý Most | Economy | $94 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/26/2026 10:00:00 PM to Černý Most, Prague (Czech Republic) arriving at 7/27/2026 4:10:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 18h 10m
|
||
| FlixBus | 17h 35m | 5:20 AM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 10:55 PM | Prague | Na Knížecí Station | Economy | $96 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/26/2026 5:20:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 7/26/2026 10:55:00 PM. 50 Economy ticket for $96 per person are available. Travel duration is 17h 35m
|
||
| FlixBus | 19h 25m | 5:20 AM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 12:45 AM | Prague | Wilsonova Bus Station | Economy | $97 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/26/2026 5:20:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 7/27/2026 12:45:00 AM. 50 Economy ticket for $97 per person are available. Travel duration is 19h 25m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 14h 50m | 6:05 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 8:55 AM | Prague | Na Knížecí Station | Economy | $90 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/27/2026 6:05:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 7/28/2026 8:55:00 AM. 50 Economy ticket for $90 per person are available. Travel duration is 14h 50m
|
||
| FlixBus | 17h 5m | 9:30 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 2:35 PM | Prague | Wilsonova Bus Station | Economy | $90 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/27/2026 9:30:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 7/28/2026 2:35:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 17h 5m
|
||
| FlixBus | 16h 30m | 5:20 AM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 9:50 PM | Prague | ÚAN Florenc | Economy | $90 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/27/2026 5:20:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 7/27/2026 9:50:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 16h 30m
|
||
| BlaBlaCar Bus | 18h 50m | 2:55 PM | Lyon | Perrache Train Station | 9:45 AM | Prague | ÚAN Florenc | Economy | $91 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/27/2026 2:55:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 7/28/2026 9:45:00 AM. 50 Economy ticket for $91 per person are available. Travel duration is 18h 50m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 5m | 9:30 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 2:35 PM | Prague | Wilsonova Bus Station | Economy | $80 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/28/2026 9:30:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 7/29/2026 2:35:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 17h 5m
|
||
| FlixBus | 16h 30m | 5:20 AM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 9:50 PM | Prague | ÚAN Florenc | Economy | $80 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/28/2026 5:20:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 7/28/2026 9:50:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 16h 30m
|
||
| FlixBus | 17h 15m | 9:30 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 2:45 PM | Prague | ÚAN Florenc | Economy | $80 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/28/2026 9:30:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 7/29/2026 2:45:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 17h 15m
|
||
| FlixBus | 17h 35m | 5:20 AM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 10:55 PM | Prague | Na Knížecí Station | Economy | $83 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/28/2026 5:20:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 7/28/2026 10:55:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 17h 35m
|
||
| FlixBus | 19h 25m | 5:20 AM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 12:45 AM | Prague | Wilsonova Bus Station | Economy | $83 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/28/2026 5:20:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 7/29/2026 12:45:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 19h 25m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 19h 25m | 5:20 AM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 12:45 AM | Prague | Wilsonova Bus Station | Economy | $83 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/29/2026 5:20:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 7/30/2026 12:45:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 19h 25m
|
||
| FlixBus | 20h 50m | 12:20 AM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 9:10 PM | Prague | Na Knížecí Station | Economy | $84 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/29/2026 12:20:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 7/29/2026 9:10:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 20h 50m
|
||
| FlixBus | 17h 35m | 5:20 AM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 10:55 PM | Prague | Na Knížecí Station | Economy | $85 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/29/2026 5:20:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 7/29/2026 10:55:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 17h 35m
|
||
| FlixBus | 20h 25m | 12:05 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 8:30 AM | Prague | Zličín | Economy | $85 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/29/2026 12:05:00 PM to Zličín, Prague (Czech Republic) arriving at 7/30/2026 8:30:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 20h 25m
|
||
| FlixBus | 16h 30m | 5:20 AM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 9:50 PM | Prague | ÚAN Florenc | Economy | $90 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/29/2026 5:20:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 7/29/2026 9:50:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 16h 30m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 16h 30m | 5:20 AM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 9:50 PM | Prague | ÚAN Florenc | Economy | $88 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/30/2026 5:20:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 7/30/2026 9:50:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 16h 30m
|
||
| FlixBus | 17h 35m | 5:20 AM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 10:55 PM | Prague | Na Knížecí Station | Economy | $90 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/30/2026 5:20:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 7/30/2026 10:55:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 17h 35m
|
||
| FlixBus | 19h 25m | 5:20 AM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 12:45 AM | Prague | Wilsonova Bus Station | Economy | $91 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/30/2026 5:20:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 7/31/2026 12:45:00 AM. 50 Economy ticket for $91 per person are available. Travel duration is 19h 25m
|
||
| FlixBus | 20h 25m | 12:05 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 8:30 AM | Prague | Zličín | Economy | $91 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/30/2026 12:05:00 PM to Zličín, Prague (Czech Republic) arriving at 7/31/2026 8:30:00 AM. 50 Economy ticket for $91 per person are available. Travel duration is 20h 25m
|
||
| FlixBus | 19h 45m | 12:05 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 7:50 AM | Prague | ÚAN Florenc | Economy | $97 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/30/2026 12:05:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 7/31/2026 7:50:00 AM. 50 Economy ticket for $97 per person are available. Travel duration is 19h 45m
|
Best Price Offer: The price for the cheapest bus from Lyon to Prague is $75 on 8/5/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Lyon and Prague
Facts about the bus from Lyon to Prague
Compare all providers like FlixBus and BlaBlaCar Bus that travel 15 times every day by bus from Lyon to Prague in one click! Book your bus ticket from Lyon to Prague starting from $75!
| Cheapest Bus | $75 |
| Fastest Bus | 14h 50m |
| Earliest Bus | 12:20 AM |
| Latest Bus | 10:00 PM |
| Daily Bus Routes | 15 Ø |
| Distance | 535.0 miles |
| Bus Companies | FlixBus and BlaBlaCar Bus |
Cheapest bus connections from Lyon to Prague
Every day, 15 buses from 2 bus companies leave Lyon for Prague: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/24/2026 and for the following days.
The cheapest time to travel from Lyon to Prague
How to save money travelling from Lyon to Prague
Book the ticket from Lyon to Prague in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Lyon to Prague, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Lyon to Prague are also emptier.Latest reviews for bus companies on the route Lyon - Prague
All bus stations and stops in Lyon and Prague
In the map below, you can see where to find all bus stations in Lyon and Prague.
Service and Comfort on the bus from Lyon to Prague
FAQs about the Lyon to Prague bus
How much does a Lyon Prague bus trip cost?
How much could I save by comparing buses from Lyon to Prague?
On average, how many connections are available from Lyon to Prague each day?
How long does a bus journey from Lyon to Prague take?
What time is the first bus from Lyon to Prague?
What time is the last bus from Lyon to Prague?
Which bus companies operate the Lyon Prague route?
Is there a direct bus between Lyon and Prague?
What can I take with me on the Lyon to Prague bus route?
What equipment is available for the Lyon Prague bus route?
How does CheckMyBus find the best bus deals from Lyon to Prague?
How does CheckMyBus technology work for trips from Lyon to Prague?
Available seat classes which are offered on the bus route Lyon to Prague
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Lyon and to Prague
- Bus Routes to Lyon
- Bus from Basel to Lyon
- Buses from Berlin to Lyon
- Bus to Lyon from Béziers
- Bilbao to Lyon bus
- Buses Brest to Lyon
- From Dusseldorf to Lyon bus
- Buses from Liege to Lyon
- From Limoges to Lyon bus
- Buses Lisbon to Lyon
- Bus London - Lyon
- From Munich to Lyon bus
- Buses from Nantes to Lyon
- Buses Nice - Lyon
- Bus from Nimes to Lyon
- Bus Poitiers to Lyon
- Buses Sallanches to Lyon
- Bus Sofia - Lyon
- Buses Strasbourg - Lyon
- Buses Tours - Lyon
- Bus from Zurich to Lyon
- Bus Routes to Prague
- Bus to Prague from Amsterdam
- Buses from Bern to Prague
- Buses Bratislava - Prague
- Buses Brno to Prague
- Buses Český Krumlov - Prague
- Buses from Chisinau to Prague
- Buses Děčín to Prague
- Buses from Frankfurt am Main to Prague
- Buses to Prague from Hamburg
- From Jičín to Prague bus
- Bus to Prague from Kalush
- Bus to Prague from Krakow
- Lodz to Prague bus
- Nuremberg to Prague bus
- From Odesa to Prague bus
- Paris to Prague bus
- Buses Schwandorf - Prague
- Buses to Prague from Teplice
- Buses Wroclaw - Prague
- Bus Zurich - Prague
