Which bus from Louisville, KY to St. Louis, MO is the cheapest?

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Compare all timetables for the bus from Louisville, KY to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Louisville, KY to St. Louis, MO from various bus operators like Greyhound US for the next days.

today
$56
tomorrow
Tuesday
$53
Wednesday
$49
Thursday
Friday
Saturday
$54

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 8h 35m 7:35 AM Louisville, KY Greyhound Bus Station 3:10 PM St. Louis, MO Gateway Station  Economy $56
Greyhound US 9h 30m 2:45 PM Louisville, KY Greyhound Bus Station 11:15 PM St. Louis, MO Gateway Station  Economy $56
Greyhound US 11h 25m 10:55 PM Louisville, KY Greyhound Bus Station 9:20 AM St. Louis, MO Gateway Station  Economy $56
  • Did you know that if you travel from Louisville, KY to St. Louis, MO via Indianapolis, you can save more than $7? You can find the corresponding connections below.
    • Greyhound US
      7h 35m
      0
      8:35 AM
      Louisville, KY
      Greyhound Bus Station
      10:45 AM
      Indianapolis
      Central Bus Station
      0
      Greyhound US
      Economy
      $18
      • Waiting Time 0h 20m
    • Greyhound US
      5h 5m
      0
      11:05 AM
      Indianapolis
      Central Bus Station
      3:10 PM
      St. Louis, MO
      Gateway Station
      0
      Greyhound US
      Economy
      $31
    Travel time is the same as the direct connection, but you will save $7

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 8h 35m 7:35 AM Louisville, KY Greyhound Bus Station 3:10 PM St. Louis, MO Gateway Station  Economy $53
Greyhound US 9h 30m 2:45 PM Louisville, KY Greyhound Bus Station 11:15 PM St. Louis, MO Gateway Station  Economy $53
Greyhound US 11h 25m 10:55 PM Louisville, KY Greyhound Bus Station 9:20 AM St. Louis, MO Gateway Station  Economy $53

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 8h 35m 7:35 AM Louisville, KY Greyhound Bus Station 3:10 PM St. Louis, MO Gateway Station  Economy $49
Greyhound US 9h 30m 2:45 PM Louisville, KY Greyhound Bus Station 11:15 PM St. Louis, MO Gateway Station  Economy $49
Greyhound US 11h 25m 10:55 PM Louisville, KY Greyhound Bus Station 9:20 AM St. Louis, MO Gateway Station  Economy $50

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 8h 35m 7:35 AM Louisville, KY Greyhound Bus Station 3:10 PM St. Louis, MO Gateway Station  Economy $54
Greyhound US 9h 30m 2:45 PM Louisville, KY Greyhound Bus Station 11:15 PM St. Louis, MO Gateway Station  Economy $54
Greyhound US 11h 25m 10:55 PM Louisville, KY Greyhound Bus Station 9:20 AM St. Louis, MO Gateway Station  Economy $55
  • Did you know that if you travel from Louisville, KY to St. Louis, MO via Indianapolis, you can save more than $5? You can find the corresponding connections below.
    • Greyhound US
      7h 35m
      0
      8:35 AM
      Louisville, KY
      Greyhound Bus Station
      10:45 AM
      Indianapolis
      Central Bus Station
      0
      Greyhound US
      Economy
      $18
      • Waiting Time 0h 20m
    • Greyhound US
      5h 5m
      0
      11:05 AM
      Indianapolis
      Central Bus Station
      3:10 PM
      St. Louis, MO
      Gateway Station
      0
      Greyhound US
      Economy
      $31
    Travel time is the same as the direct connection, but you will save $5

Best Price Offer: The price for the cheapest bus from Louisville, KY to St. Louis, MO is $46 on 8/5/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Louisville, KY and St. Louis, MO

See here how frequent the connections between Louisville, KY and St. Louis, MO are, during different times and days of the week.
Sunday is the busiest day, with more than 6 daily buses from Louisville, KY to St. Louis, MO. Tuesday has instead the fewest connections, with only 3 daily coaches between Louisville, KY and St. Louis, MO.
The busiest time of the day is the Morning, with 6 buses from Louisville, KY to St. Louis, MO, while Morning sees the fewest connections between Louisville, KY and St. Louis, MO, with 6 offers.

Facts about the bus from Louisville, KY to St. Louis, MO

Compare all providers like Greyhound US that travel 4 times every day by bus from Louisville, KY to St. Louis, MO in one click! Book your bus ticket from Louisville, KY to St. Louis, MO starting from $46!

Cheapest Bus $46
Fastest Bus 7h 35m
Earliest Bus 7:35 AM
Latest Bus 10:55 PM
Daily Bus Routes 4 Ø
Distance 241.6 miles
Bus Companies Greyhound US

Cheapest bus connections from Louisville, KY to St. Louis, MO

Every day, 4 buses from 1 bus companies leave Louisville, KY for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/26/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 07/26
$60
Monday 07/27
Tuesday 07/28
$53
Wednesday 07/29
$49
Thursday 07/30
Friday 07/31
Saturday 08/01
$54
Sunday 08/02
$57
Monday 08/03
Tuesday 08/04
$50
Wednesday 08/05
$46
Thursday 08/06
$51
Friday 08/07
$51
Saturday 08/08
$48
Sunday 08/09
$54
Monday 08/10
$51
Tuesday 08/11
Wednesday 08/12
$55
Thursday 08/13
Friday 08/14
$57
Saturday 08/15
Sunday 08/16
$59
Monday 08/17
$53
Tuesday 08/18
$51
Wednesday 08/19
$48
Thursday 08/20
$57
Friday 08/21
$57
Saturday 08/22

The cheapest time to travel from Louisville, KY to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Louisville, KY to St. Louis, MO, for the next 30 days.
With a price starting from $46, Wednesday is the cheapest day for a bus from Louisville, KY to St. Louis, MO. Sunday instead is the most expensive day with prices starting from $54.
Morning is the cheapest day time for bus tickets from Louisville, KY to St. Louis, MO, with $49. Evening is the most expensive time of the day with prices starting from $50.

How to save money travelling from Louisville, KY to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Louisville, KY to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Louisville, KY to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Louisville, KY to St. Louis, MO are also emptier.

Beloved bus companies from Louisville, KY to St. Louis, MO

These are the most booked bus companies between Louisville, KY to St. Louis, MO from our users.

Greyhound US from Louisville, KY to St. Louis, MO

Greyhound US

Here you will find the key facts about the Greyhound US bus route Louisville, KY to St. Louis, MO:

Cheapest Price $49
Fastest Bus 7h 35m
Earliest Bus 7:35 AM
Last Bus 10:55 PM
Daily Connections 4 Ø
Found on 7/1/2026

All bus stations and stops in Louisville, KY and St. Louis, MO

In the map below, you can see where to find all bus stations in Louisville, KY and St. Louis, MO.

Service and Comfort on the bus from Louisville, KY to St. Louis, MO

Want to know which seat classes are available on the buses from Louisville, KY to St. Louis, MO? Or which bus companies serve the route Louisville, KY to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Louisville, KY to St. Louis, MO bus

How much does a Louisville, KY St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $46 and takes 7h 35m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Louisville, KY to St. Louis, MO?

This route is offered by 1 companies with a range of ticket prices between $46 and $60. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Louisville, KY to St. Louis, MO each day?

Every day, the Louisville, KY to St. Louis, MO bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Louisville, KY to St. Louis, MO take?

The fastest bus from Louisville, KY to St. Louis, MO is offered by Greyhound US and takes 7h 35m. Bus tickets for this connection cost $56. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Louisville, KY to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Louisville, KY starts at 7:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Louisville, KY to St. Louis, MO?

The latest bus trip departing from Louisville, KY for St. Louis, MO starts at 10:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Louisville, KY St. Louis, MO route?

When traveling by bus from Louisville, KY to St. Louis, MO, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Louisville, KY and St. Louis, MO?

You can check all the direct connections between Louisville, KY and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Louisville, KY to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Louisville, KY St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Louisville, KY St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Louisville, KY to St. Louis, MO on your planned travel date.

How does CheckMyBus find the best bus deals from Louisville, KY to St. Louis, MO?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 4 daily trips between Louisville, KY and St. Louis, MO. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Louisville, KY to St. Louis, MO?

Prices and availability for 4 trips between Louisville, KY and St. Louis, MO change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Louisville, KY to St. Louis, MO

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Louisville, KY and to St. Louis, MO

Here’s an overview of the most popular bus routes to Louisville, KY and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!
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