Compare all timetables for the bus from Karlsruhe to Madrid
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlaBlaCar Bus | 26h 50m | 11:15 AM | Karlsruhe | Central Station | 2:05 PM | Madrid | Sur Bus Station | Economy | $91 |
A Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 7/26/2026 11:15:00 AM to Sur Bus Station, Madrid (Spain) arriving at 7/27/2026 2:05:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 26h 50m
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| FlixBus | 28h 35m | 4:05 AM | Karlsruhe | Central Station | 8:40 AM | Madrid | Sur Bus Station | Economy | $111 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/26/2026 4:05:00 AM to Sur Bus Station, Madrid (Spain) arriving at 7/27/2026 8:40:00 AM. 50 Economy ticket for $111 per person are available. Travel duration is 28h 35m
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| FlixBus | 32h 45m | 11:10 PM | Karlsruhe | Central Station | 7:55 AM | Madrid | Sur Bus Station | Economy | $121 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/26/2026 11:10:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/28/2026 7:55:00 AM. 50 Economy ticket for $121 per person are available. Travel duration is 32h 45m
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| FlixBus | 34h 50m | 11:40 PM | Karlsruhe | Central Station | 10:30 AM | Madrid | Sur Bus Station | Economy | $128 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/26/2026 11:40:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/28/2026 10:30:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 34h 50m
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| BlaBlaCar Bus | 27h 35m | 9:05 PM | Karlsruhe | Central Station | 12:40 AM | Madrid | Sur Bus Station | Economy | $133 |
A Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 7/26/2026 9:05:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/28/2026 12:40:00 AM. 50 Economy ticket for $133 per person are available. Travel duration is 27h 35m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 28h 35m | 4:05 AM | Karlsruhe | Central Station | 8:40 AM | Madrid | Sur Bus Station | Economy | $115 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/27/2026 4:05:00 AM to Sur Bus Station, Madrid (Spain) arriving at 7/28/2026 8:40:00 AM. 50 Economy ticket for $115 per person are available. Travel duration is 28h 35m
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| FlixBus | 34h 50m | 11:40 PM | Karlsruhe | Central Station | 10:30 AM | Madrid | Sur Bus Station | Economy | $115 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/27/2026 11:40:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/29/2026 10:30:00 AM. 50 Economy ticket for $115 per person are available. Travel duration is 34h 50m
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| FlixBus | 27h 20m | 8:10 AM | Karlsruhe | Central Station | 11:30 AM | Madrid | Sur Bus Station | Economy | $127 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/27/2026 8:10:00 AM to Sur Bus Station, Madrid (Spain) arriving at 7/28/2026 11:30:00 AM. 50 Economy ticket for $127 per person are available. Travel duration is 27h 20m
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| BlaBlaCar Bus | 27h 35m | 9:05 PM | Karlsruhe | Central Station | 12:40 AM | Madrid | Sur Bus Station | Economy | $127 |
A Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 7/27/2026 9:05:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/29/2026 12:40:00 AM. 50 Economy ticket for $127 per person are available. Travel duration is 27h 35m
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FlixBus29h 35m04:05 AMKarlsruheCentral Station12:50 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/28/2026 4:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 7/28/2026 12:50:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 8h 45m
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FlixBus16h 40m05:00 PMLyonLyon Avenue Tony Garnier Bus Stop9:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/28/2026 5:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/29/2026 9:40:00 AM. 50 Economy ticket for $45 per person are available. Travel duration is 16h 40m
Waiting Time 4h 10m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 28h 35m | 4:05 AM | Karlsruhe | Central Station | 8:40 AM | Madrid | Sur Bus Station | Economy | $98 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/28/2026 4:05:00 AM to Sur Bus Station, Madrid (Spain) arriving at 7/29/2026 8:40:00 AM. 50 Economy ticket for $98 per person are available. Travel duration is 28h 35m
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| FlixBus | 27h 20m | 8:10 AM | Karlsruhe | Central Station | 11:30 AM | Madrid | Sur Bus Station | Economy | $102 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/28/2026 8:10:00 AM to Sur Bus Station, Madrid (Spain) arriving at 7/29/2026 11:30:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 27h 20m
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| FlixBus | 31h 20m | 12:35 AM | Karlsruhe | Central Station | 7:55 AM | Madrid | Sur Bus Station | Economy | $117 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/28/2026 12:35:00 AM to Sur Bus Station, Madrid (Spain) arriving at 7/29/2026 7:55:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 31h 20m
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| FlixBus | 26h 20m | 11:00 AM | Karlsruhe | Central Station | 1:20 PM | Madrid | Sur Bus Station | Economy | $119 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/28/2026 11:00:00 AM to Sur Bus Station, Madrid (Spain) arriving at 7/29/2026 1:20:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 26h 20m
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| FlixBus | 32h 45m | 11:10 PM | Karlsruhe | Central Station | 7:55 AM | Madrid | Sur Bus Station | Economy | $119 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/28/2026 11:10:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/30/2026 7:55:00 AM. 50 Economy ticket for $119 per person are available. Travel duration is 32h 45m
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BlaBlaCar Bus26h 50m011:15 AMKarlsruheCentral Station8:45 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 7/29/2026 11:15:00 AM to Perrache Train Station, Lyon (France) arriving at 7/29/2026 8:45:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 9h 30m
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ALSA17h 15m08:50 PMLyonLyon Avenue Tony Garnier Bus Stop2:05 PMMadridMendez Alvaro Train Station0EconomyA Bus from ALSA goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/29/2026 8:50:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 7/30/2026 2:05:00 PM. 50 Economy ticket for $45 per person are available. Travel duration is 17h 15m
Waiting Time 0h 5m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 32h 45m | 11:10 PM | Karlsruhe | Central Station | 7:55 AM | Madrid | Sur Bus Station | Economy | $117 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/29/2026 11:10:00 PM to Sur Bus Station, Madrid (Spain) arriving at 7/31/2026 7:55:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 32h 45m
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| FlixBus | 28h 35m | 4:05 AM | Karlsruhe | Central Station | 8:40 AM | Madrid | Sur Bus Station | Economy | $121 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/29/2026 4:05:00 AM to Sur Bus Station, Madrid (Spain) arriving at 7/30/2026 8:40:00 AM. 50 Economy ticket for $121 per person are available. Travel duration is 28h 35m
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| FlixBus | 28h 5m | 7:25 AM | Karlsruhe | Central Station | 11:30 AM | Madrid | Sur Bus Station | Economy | $121 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/29/2026 7:25:00 AM to Sur Bus Station, Madrid (Spain) arriving at 7/30/2026 11:30:00 AM. 50 Economy ticket for $121 per person are available. Travel duration is 28h 5m
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| FlixBus | 26h 20m | 11:00 AM | Karlsruhe | Central Station | 1:20 PM | Madrid | Sur Bus Station | Economy | $129 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/29/2026 11:00:00 AM to Sur Bus Station, Madrid (Spain) arriving at 7/30/2026 1:20:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 26h 20m
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| FlixBus | 31h 20m | 12:35 AM | Karlsruhe | Central Station | 7:55 AM | Madrid | Sur Bus Station | Economy | $140 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/29/2026 12:35:00 AM to Sur Bus Station, Madrid (Spain) arriving at 7/30/2026 7:55:00 AM. 50 Economy ticket for $140 per person are available. Travel duration is 31h 20m
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BlaBlaCar Bus26h 50m011:15 AMKarlsruheCentral Station8:45 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 7/29/2026 11:15:00 AM to Perrache Train Station, Lyon (France) arriving at 7/29/2026 8:45:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 9h 30m
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ALSA17h 15m08:50 PMLyonLyon Avenue Tony Garnier Bus Stop2:05 PMMadridMendez Alvaro Train Station0EconomyA Bus from ALSA goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/29/2026 8:50:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 7/30/2026 2:05:00 PM. 50 Economy ticket for $45 per person are available. Travel duration is 17h 15m
Waiting Time 0h 5m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 28h 35m | 4:05 AM | Karlsruhe | Central Station | 8:40 AM | Madrid | Sur Bus Station | Economy | $132 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/31/2026 4:05:00 AM to Sur Bus Station, Madrid (Spain) arriving at 8/1/2026 8:40:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 28h 35m
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| FlixBus | 27h 20m | 8:10 AM | Karlsruhe | Central Station | 11:30 AM | Madrid | Sur Bus Station | Economy | $164 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/31/2026 8:10:00 AM to Sur Bus Station, Madrid (Spain) arriving at 8/1/2026 11:30:00 AM. 50 Economy ticket for $164 per person are available. Travel duration is 27h 20m
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| FlixBus | 26h 20m | 11:00 AM | Karlsruhe | Central Station | 1:20 PM | Madrid | Sur Bus Station | Economy | $188 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/31/2026 11:00:00 AM to Sur Bus Station, Madrid (Spain) arriving at 8/1/2026 1:20:00 PM. 50 Economy ticket for $188 per person are available. Travel duration is 26h 20m
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| FlixBus | 26h 20m | 6:35 AM | Karlsruhe | Central Station | 8:55 AM | Madrid | Sur Bus Station | Economy | $193 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/31/2026 6:35:00 AM to Sur Bus Station, Madrid (Spain) arriving at 8/1/2026 8:55:00 AM. 50 Economy ticket for $193 per person are available. Travel duration is 26h 20m
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| FlixBus | 32h 45m | 11:10 PM | Karlsruhe | Central Station | 7:55 AM | Madrid | Sur Bus Station | Economy | $200 |
A Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 7/31/2026 11:10:00 PM to Sur Bus Station, Madrid (Spain) arriving at 8/2/2026 7:55:00 AM. 50 Economy ticket for $200 per person are available. Travel duration is 32h 45m
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BlaBlaCar Bus26h 50m011:15 AMKarlsruheCentral Station8:45 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 7/29/2026 11:15:00 AM to Perrache Train Station, Lyon (France) arriving at 7/29/2026 8:45:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 9h 30m
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ALSA17h 15m08:50 PMLyonLyon Avenue Tony Garnier Bus Stop2:05 PMMadridMendez Alvaro Train Station0EconomyA Bus from ALSA goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/29/2026 8:50:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 7/30/2026 2:05:00 PM. 50 Economy ticket for $45 per person are available. Travel duration is 17h 15m
Waiting Time 0h 5m -
Best Price Offer: The price for the cheapest bus from Karlsruhe to Madrid is $91 on 7/26/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Karlsruhe and Madrid
Facts about the bus from Karlsruhe to Madrid
Compare all providers like FlixBus and BlaBlaCar Bus that travel 8 times every day by bus from Karlsruhe to Madrid in one click! Book your bus ticket from Karlsruhe to Madrid starting from $91!
| Cheapest Bus | $91 |
| Fastest Bus | 26h 20m |
| Earliest Bus | 12:35 AM |
| Latest Bus | 11:40 PM |
| Daily Bus Routes | 8 Ø |
| Distance | 838.4 miles |
| Bus Companies | FlixBus and BlaBlaCar Bus |
Cheapest bus connections from Karlsruhe to Madrid
Every day, 8 buses from 2 bus companies leave Karlsruhe for Madrid: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/25/2026 and for the following days.
The cheapest time to travel from Karlsruhe to Madrid
How to save money travelling from Karlsruhe to Madrid
Book the ticket from Karlsruhe to Madrid in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Karlsruhe to Madrid, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Karlsruhe to Madrid are also emptier.All bus stations and stops in Karlsruhe and Madrid
In the map below, you can see where to find all bus stations in Karlsruhe and Madrid.
Service and Comfort on the bus from Karlsruhe to Madrid
FAQs about the Karlsruhe to Madrid bus
How much does a Karlsruhe Madrid bus trip cost?
How much could I save by comparing buses from Karlsruhe to Madrid?
On average, how many connections are available from Karlsruhe to Madrid each day?
How long does a bus journey from Karlsruhe to Madrid take?
What time is the first bus from Karlsruhe to Madrid?
What time is the last bus from Karlsruhe to Madrid?
Which bus companies operate the Karlsruhe Madrid route?
Is there a direct bus between Karlsruhe and Madrid?
What can I take with me on the Karlsruhe to Madrid bus route?
What equipment is available for the Karlsruhe Madrid bus route?
How does CheckMyBus find the best bus deals from Karlsruhe to Madrid?
How does CheckMyBus technology work for trips from Karlsruhe to Madrid?
Available seat classes which are offered on the bus route Karlsruhe to Madrid
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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