Compare all timetables for the bus from Guatemala City to Santa Ana
Here is a selection of the cheapest bus trips from the schedule from Guatemala City to Santa Ana from various bus operators like Cristobal Colon for the next days.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cristobal Colon | 5h 20m | 6:00 AM | Guatemala City | Monja Blanca | 11:20 AM | Santa Ana | Puma Santa Maria Gas Station | First Class | $22 |
A Bus from Cristobal Colon goes from Monja Blanca, Guatemala City (Guatemala) at 7/27/2026 6:00:00 AM to Puma Santa Maria Gas Station, Santa Ana (El Salvador) arriving at 7/27/2026 11:20:00 AM. 50 First Class ticket for $22 per person are available. Travel duration is 5h 20m
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| Cristobal Colon | 5h 20m | 4:00 PM | Guatemala City | Monja Blanca | 9:20 PM | Santa Ana | Puma Santa Maria Gas Station | First Class | $22 |
A Bus from Cristobal Colon goes from Monja Blanca, Guatemala City (Guatemala) at 7/27/2026 4:00:00 PM to Puma Santa Maria Gas Station, Santa Ana (El Salvador) arriving at 7/27/2026 9:20:00 PM. 50 First Class ticket for $22 per person are available. Travel duration is 5h 20m
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Best Price Offer: The price for the cheapest bus from Guatemala City to Santa Ana is $22 on 7/27/2026. Flexible travelers save on ticket prices.
Facts about the bus from Guatemala City to Santa Ana
Compare all providers like Cristobal Colon that travel 2 times every day by bus from Guatemala City to Santa Ana in one click! Book your bus ticket from Guatemala City to Santa Ana starting from $22!
| Cheapest Bus | $22 |
| Fastest Bus | 5h 20m |
| Earliest Bus | 6:00 AM |
| Latest Bus | 4:00 PM |
| Daily Bus Routes | 2 Ø |
| Distance | 77.9 miles |
| Bus Companies | Cristobal Colon |
Cheapest bus connections from Guatemala City to Santa Ana
Every day, 2 buses from 1 bus companies leave Guatemala City for Santa Ana: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/27/2026 and for the following days.
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
07/26
Monday
07/27
$22
Tuesday
07/28
Wednesday
07/29
$88
Thursday
07/30
$88
Friday
07/31
$88
Saturday
08/01
$88
Sunday
08/02
$88
Monday
08/03
Tuesday
08/04
$88
Wednesday
08/05
$88
Thursday
08/06
$88
Friday
08/07
Saturday
08/08
$88
Sunday
08/09
$88
Monday
08/10
$22
Tuesday
08/11
$22
Wednesday
08/12
$88
Thursday
08/13
Friday
08/14
$88
Saturday
08/15
$22
Sunday
08/16
Monday
08/17
$88
Tuesday
08/18
$88
Wednesday
08/19
$88
Thursday
08/20
$89
Friday
08/21
$22
Saturday
08/22
How to save money travelling from Guatemala City to Santa Ana
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:
Book the ticket from Guatemala City to Santa Ana in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Guatemala City to Santa Ana, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Guatemala City to Santa Ana are also emptier.Beloved bus companies from Guatemala City to Santa Ana
These are the most booked bus companies between Guatemala City to Santa Ana from our users.
Cristobal Colon from Guatemala City to Santa Ana
Here you will find the key facts about the Cristobal Colon bus route Guatemala City to Santa Ana:
| Cheapest Price | $22 |
| Fastest Bus | 5h 20m |
| Earliest Bus | 6:00 AM |
| Last Bus | 4:00 PM |
| Daily Connections | 2 Ø |
| Found on | 7/25/2026 |
All bus stations and stops in Guatemala City and Santa Ana
In the map below, you can see where to find all bus stations in Guatemala City and Santa Ana.
Service and Comfort on the bus from Guatemala City to Santa Ana
Want to know which seat classes are available on the buses from Guatemala City to Santa Ana? Or which bus companies serve the route Guatemala City to Santa Ana? Below you will find answers to your questions.
FAQs about the Guatemala City to Santa Ana bus
How much does a Guatemala City Santa Ana bus trip cost?
This depends on, among other things, the day and time of travel. The cheapest trip is available from $22 and takes 5h 20m to reach Santa Ana. Compare offers to save money!
How much could I save by comparing buses from Guatemala City to Santa Ana?
This route is offered by 1 companies with a range of ticket prices between $22 and $23. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santa Ana.
On average, how many connections are available from Guatemala City to Santa Ana each day?
Every day, the Guatemala City to Santa Ana bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.
How long does a bus journey from Guatemala City to Santa Ana take?
The fastest bus from Guatemala City to Santa Ana is offered by Cristobal Colon and takes 5h 20m. Bus tickets for this connection cost $22. In this context, bear in mind that the journey can take longer due to traffic.
What time is the first bus from Guatemala City to Santa Ana?
The earliest bus arriving in Santa Ana from Guatemala City starts at 6:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.
What time is the last bus from Guatemala City to Santa Ana?
The latest bus trip departing from Guatemala City for Santa Ana starts at 4:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.
Which bus companies operate the Guatemala City Santa Ana route?
When traveling by bus from Guatemala City to Santa Ana, passengers can travel with Cristobal Colon. With our search, you can compare all available bus tickets to book the one that works for you.
Is there a direct bus between Guatemala City and Santa Ana?
You can check all the direct connections between Guatemala City and Santa Ana by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Cristobal Colon.
What can I take with me on the Guatemala City to Santa Ana bus route?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Guatemala City Santa Ana bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.
What equipment is available for the Guatemala City Santa Ana bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Guatemala City to Santa Ana on your planned travel date.
How does CheckMyBus find the best bus deals from Guatemala City to Santa Ana?
CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Guatemala City and Santa Ana. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.
How does CheckMyBus technology work for trips from Guatemala City to Santa Ana?
Prices and availability for 2 trips between Guatemala City and Santa Ana change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.
Available seat classes which are offered on the bus route Guatemala City to Santa Ana
First Class
Best of the best: you will find the most comfortable accommodation to work or relax during your travel.
More bus routes to Guatemala City and to Santa Ana
Here’s an overview of the most popular bus routes to Guatemala City and to Santa Ana. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Guatemala City and to Santa Ana
