Bus Frankfurt am Main to Lyon - Compare all Companies

Compare all timetables for the bus from Frankfurt am Main to Lyon

Here is a selection of the cheapest bus trips from the schedule from Frankfurt am Main to Lyon from various bus operators like FlixBus or BlaBlaCar Bus for the next days.

today

$68

tomorrow

$45

Tuesday

$45

Wednesday

$57

Thursday

$66

Friday

$66

Saturday

$68

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
BlaBlaCar Bus	11h 50m	8:55 AM	Frankfurt am Main	Central Bus Station	8:45 PM	Lyon	Perrache Train Station	Economy	$68	A Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 7/26/2026 8:55:00 AM to Perrache Train Station, Lyon (France) arriving at 7/26/2026 8:45:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 11h 50m
FlixBus	12h 35m	8:15 AM	Frankfurt am Main	Central Station	8:50 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$73	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/26/2026 8:15:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 7/26/2026 8:50:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 12h 35m
FlixBus	11h 55m	11:20 AM	Frankfurt am Main	Central Station	11:15 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$73	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/26/2026 11:20:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 7/26/2026 11:15:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 11h 55m
BlaBlaCar Bus	10h 40m	6:30 PM	Frankfurt am Main	Central Bus Station	5:10 AM	Lyon	Perrache Train Station	Economy	$74	A Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 7/26/2026 6:30:00 PM to Perrache Train Station, Lyon (France) arriving at 7/27/2026 5:10:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 10h 40m
FlixBus	11h 45m	10:45 PM	Frankfurt am Main	Central Station	10:30 AM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$75	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/26/2026 10:45:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 7/27/2026 10:30:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 11h 45m

Did you know that if you travel from Frankfurt am Main to Lyon via Colmar, you can save more than $29? You can find the corresponding connections below.
- BlaBlaCar Bus
  
  10h 40m
  
  0
  
  6:30 PM
  
  Frankfurt am Main
  Central Bus Station
  
  11:20 PM
  
  Colmar
  Bus Stop
  
  0
  
  Economy
  
  $8
  
  A Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 7/27/2026 6:30:00 PM to Bus Stop, Colmar (France) arriving at 7/27/2026 11:20:00 PM. 50 Economy ticket for $8 per person are available. Travel duration is 4h 50m
- BlaBlaCar Bus
  
  5h 45m
  
  0
  
  11:25 PM
  
  Colmar
  Bus Stop
  
  5:10 AM
  
  Lyon
  Perrache Train Station
  
  0
  
  Economy
  
  $31
  
  A Bus from BlaBlaCar Bus goes from Bus Stop, Colmar (France) at 7/27/2026 11:25:00 PM to Perrache Train Station, Lyon (France) arriving at 7/28/2026 5:10:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 5h 45m
Travel time is the same as the direct connection, but you will save $29

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
BlaBlaCar Bus	10h 40m	6:30 PM	Frankfurt am Main	Central Bus Station	5:10 AM	Lyon	Perrache Train Station	Economy	$45	A Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 7/27/2026 6:30:00 PM to Perrache Train Station, Lyon (France) arriving at 7/28/2026 5:10:00 AM. 50 Economy ticket for $45 per person are available. Travel duration is 10h 40m
FlixBus	12h 35m	8:15 AM	Frankfurt am Main	Central Station	8:50 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$63	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/27/2026 8:15:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 7/27/2026 8:50:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 12h 35m
FlixBus	12h 5m	12:45 AM	Frankfurt am Main	Central Station	12:50 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$66	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/27/2026 12:45:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 7/27/2026 12:50:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 12h 5m
FlixBus	11h 55m	11:20 AM	Frankfurt am Main	Central Station	11:15 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$66	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/27/2026 11:20:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 7/27/2026 11:15:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 11h 55m

Did you know that if you travel from Frankfurt am Main to Lyon via Colmar, you can save more than $6? You can find the corresponding connections below.
- BlaBlaCar Bus
  
  10h 40m
  
  0
  
  6:30 PM
  
  Frankfurt am Main
  Central Bus Station
  
  11:20 PM
  
  Colmar
  Bus Stop
  
  0
  
  Economy
  
  $8
  
  A Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 7/27/2026 6:30:00 PM to Bus Stop, Colmar (France) arriving at 7/27/2026 11:20:00 PM. 50 Economy ticket for $8 per person are available. Travel duration is 4h 50m
- BlaBlaCar Bus
  
  5h 45m
  
  0
  
  11:25 PM
  
  Colmar
  Bus Stop
  
  5:10 AM
  
  Lyon
  Perrache Train Station
  
  0
  
  Economy
  
  $31
  
  A Bus from BlaBlaCar Bus goes from Bus Stop, Colmar (France) at 7/27/2026 11:25:00 PM to Perrache Train Station, Lyon (France) arriving at 7/28/2026 5:10:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 5h 45m
Travel time is the same as the direct connection, but you will save $6

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
BlaBlaCar Bus	10h 40m	6:30 PM	Frankfurt am Main	Central Bus Station	5:10 AM	Lyon	Perrache Train Station	Economy	$45	A Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 7/28/2026 6:30:00 PM to Perrache Train Station, Lyon (France) arriving at 7/29/2026 5:10:00 AM. 50 Economy ticket for $45 per person are available. Travel duration is 10h 40m
FlixBus	12h 35m	8:15 AM	Frankfurt am Main	Central Station	8:50 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$57	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/28/2026 8:15:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 7/28/2026 8:50:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 12h 35m
FlixBus	11h 55m	11:20 AM	Frankfurt am Main	Central Station	11:15 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$62	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/28/2026 11:20:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 7/28/2026 11:15:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 11h 55m
FlixBus	12h 50m	3:30 PM	Frankfurt am Main	Central Station	4:20 AM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$62	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/28/2026 3:30:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 7/29/2026 4:20:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 12h 50m

Did you know that if you travel from Frankfurt am Main to Lyon via Mannheim, you can save more than $10? You can find the corresponding connections below.
- BlaBlaCar Bus
  
  10h 40m
  
  0
  
  6:30 PM
  
  Frankfurt am Main
  Central Bus Station
  
  8:00 PM
  
  Mannheim
  Central Bus Station
  
  0
  
  Economy
  
  $5
  
  A Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 7/29/2026 6:30:00 PM to Central Bus Station, Mannheim (Germany) arriving at 7/29/2026 8:00:00 PM. 50 Economy ticket for $5 per person are available. Travel duration is 1h 30m
- BlaBlaCar Bus
  
  9h 5m
  
  0
  
  8:05 PM
  
  Mannheim
  Central Bus Station
  
  5:10 AM
  
  Lyon
  Perrache Train Station
  
  0
  
  Economy
  
  $30
  
  A Bus from BlaBlaCar Bus goes from Central Bus Station, Mannheim (Germany) at 7/29/2026 8:05:00 PM to Perrache Train Station, Lyon (France) arriving at 7/30/2026 5:10:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 9h 5m
Travel time is the same as the direct connection, but you will save $10

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	11h 45m	10:45 PM	Frankfurt am Main	Central Station	10:30 AM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$57	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/29/2026 10:45:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 7/30/2026 10:30:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 11h 45m
BlaBlaCar Bus	11h 50m	8:55 AM	Frankfurt am Main	Central Bus Station	8:45 PM	Lyon	Perrache Train Station	Economy	$57	A Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 7/29/2026 8:55:00 AM to Perrache Train Station, Lyon (France) arriving at 7/29/2026 8:45:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 11h 50m
BlaBlaCar Bus	10h 40m	6:30 PM	Frankfurt am Main	Central Bus Station	5:10 AM	Lyon	Perrache Train Station	Economy	$57	A Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 7/29/2026 6:30:00 PM to Perrache Train Station, Lyon (France) arriving at 7/30/2026 5:10:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 10h 40m
FlixBus	12h 35m	8:15 AM	Frankfurt am Main	Central Station	8:50 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$59	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/29/2026 8:15:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 7/29/2026 8:50:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 12h 35m
FlixBus	12h 5m	12:45 AM	Frankfurt am Main	Central Station	12:50 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$63	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/29/2026 12:45:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 7/29/2026 12:50:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 12h 5m

Did you know that if you travel from Frankfurt am Main to Lyon via Mannheim, you can save more than $22? You can find the corresponding connections below.
- BlaBlaCar Bus
  
  10h 40m
  
  0
  
  6:30 PM
  
  Frankfurt am Main
  Central Bus Station
  
  8:00 PM
  
  Mannheim
  Central Bus Station
  
  0
  
  Economy
  
  $5
  
  A Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 7/29/2026 6:30:00 PM to Central Bus Station, Mannheim (Germany) arriving at 7/29/2026 8:00:00 PM. 50 Economy ticket for $5 per person are available. Travel duration is 1h 30m
- BlaBlaCar Bus
  
  9h 5m
  
  0
  
  8:05 PM
  
  Mannheim
  Central Bus Station
  
  5:10 AM
  
  Lyon
  Perrache Train Station
  
  0
  
  Economy
  
  $30
  
  A Bus from BlaBlaCar Bus goes from Central Bus Station, Mannheim (Germany) at 7/29/2026 8:05:00 PM to Perrache Train Station, Lyon (France) arriving at 7/30/2026 5:10:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 9h 5m
Travel time is the same as the direct connection, but you will save $22

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	12h 5m	12:45 AM	Frankfurt am Main	Central Station	12:50 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$66	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/30/2026 12:45:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 7/30/2026 12:50:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 12h 5m
FlixBus	11h 55m	11:20 AM	Frankfurt am Main	Central Station	11:15 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$66	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/30/2026 11:20:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 7/30/2026 11:15:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 11h 55m
FlixBus	12h 35m	8:15 AM	Frankfurt am Main	Central Station	8:50 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$70	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/30/2026 8:15:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 7/30/2026 8:50:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 12h 35m
BlaBlaCar Bus	10h 40m	6:30 PM	Frankfurt am Main	Central Bus Station	5:10 AM	Lyon	Perrache Train Station	Economy	$74	A Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 7/30/2026 6:30:00 PM to Perrache Train Station, Lyon (France) arriving at 7/31/2026 5:10:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 10h 40m

Did you know that if you travel from Frankfurt am Main to Lyon via Mannheim, you can save more than $31? You can find the corresponding connections below.
- BlaBlaCar Bus
  
  10h 40m
  
  0
  
  6:30 PM
  
  Frankfurt am Main
  Central Bus Station
  
  8:00 PM
  
  Mannheim
  Central Bus Station
  
  0
  
  Economy
  
  $5
  
  A Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 7/29/2026 6:30:00 PM to Central Bus Station, Mannheim (Germany) arriving at 7/29/2026 8:00:00 PM. 50 Economy ticket for $5 per person are available. Travel duration is 1h 30m
- BlaBlaCar Bus
  
  9h 5m
  
  0
  
  8:05 PM
  
  Mannheim
  Central Bus Station
  
  5:10 AM
  
  Lyon
  Perrache Train Station
  
  0
  
  Economy
  
  $30
  
  A Bus from BlaBlaCar Bus goes from Central Bus Station, Mannheim (Germany) at 7/29/2026 8:05:00 PM to Perrache Train Station, Lyon (France) arriving at 7/30/2026 5:10:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 9h 5m
Travel time is the same as the direct connection, but you will save $31

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	11h 55m	11:20 AM	Frankfurt am Main	Central Station	11:15 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$66	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/31/2026 11:20:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 7/31/2026 11:15:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 11h 55m
FlixBus	12h 35m	8:15 AM	Frankfurt am Main	Central Station	8:50 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$68	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/31/2026 8:15:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 7/31/2026 8:50:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 12h 35m
BlaBlaCar Bus	11h 50m	8:55 AM	Frankfurt am Main	Central Bus Station	8:45 PM	Lyon	Perrache Train Station	Economy	$68	A Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 7/31/2026 8:55:00 AM to Perrache Train Station, Lyon (France) arriving at 7/31/2026 8:45:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 11h 50m
FlixBus	12h 5m	12:45 AM	Frankfurt am Main	Central Station	12:50 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$71	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 7/31/2026 12:45:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 7/31/2026 12:50:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 12h 5m
BlaBlaCar Bus	10h 40m	6:30 PM	Frankfurt am Main	Central Bus Station	5:10 AM	Lyon	Perrache Train Station	Economy	$114	A Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 7/31/2026 6:30:00 PM to Perrache Train Station, Lyon (France) arriving at 8/1/2026 5:10:00 AM. 50 Economy ticket for $114 per person are available. Travel duration is 10h 40m

Did you know that if you travel from Frankfurt am Main to Lyon via Mannheim, you can save more than $31? You can find the corresponding connections below.
- BlaBlaCar Bus
  
  10h 40m
  
  0
  
  6:30 PM
  
  Frankfurt am Main
  Central Bus Station
  
  8:00 PM
  
  Mannheim
  Central Bus Station
  
  0
  
  Economy
  
  $5
  
  A Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 7/29/2026 6:30:00 PM to Central Bus Station, Mannheim (Germany) arriving at 7/29/2026 8:00:00 PM. 50 Economy ticket for $5 per person are available. Travel duration is 1h 30m
- BlaBlaCar Bus
  
  9h 5m
  
  0
  
  8:05 PM
  
  Mannheim
  Central Bus Station
  
  5:10 AM
  
  Lyon
  Perrache Train Station
  
  0
  
  Economy
  
  $30
  
  A Bus from BlaBlaCar Bus goes from Central Bus Station, Mannheim (Germany) at 7/29/2026 8:05:00 PM to Perrache Train Station, Lyon (France) arriving at 7/30/2026 5:10:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 9h 5m
Travel time is the same as the direct connection, but you will save $31

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
BlaBlaCar Bus	10h 40m	6:30 PM	Frankfurt am Main	Central Bus Station	5:10 AM	Lyon	Perrache Train Station	Economy	$68	A Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 8/1/2026 6:30:00 PM to Perrache Train Station, Lyon (France) arriving at 8/2/2026 5:10:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 10h 40m
FlixBus	12h 35m	8:15 AM	Frankfurt am Main	Central Station	8:50 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$70	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 8/1/2026 8:15:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/1/2026 8:50:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 12h 35m
FlixBus	10h 0m	7:05 PM	Frankfurt am Main	Central Station	5:05 AM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$73	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 8/1/2026 7:05:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/2/2026 5:05:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 10h 0m
FlixBus	11h 55m	11:20 AM	Frankfurt am Main	Central Station	11:15 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$90	A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 8/1/2026 11:20:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/1/2026 11:15:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 11h 55m

Did you know that if you travel from Frankfurt am Main to Lyon via Mannheim, you can save more than $33? You can find the corresponding connections below.
- BlaBlaCar Bus
  
  10h 40m
  
  0
  
  6:30 PM
  
  Frankfurt am Main
  Central Bus Station
  
  8:00 PM
  
  Mannheim
  Central Bus Station
  
  0
  
  Economy
  
  $5
  
  A Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 7/29/2026 6:30:00 PM to Central Bus Station, Mannheim (Germany) arriving at 7/29/2026 8:00:00 PM. 50 Economy ticket for $5 per person are available. Travel duration is 1h 30m
- BlaBlaCar Bus
  
  9h 5m
  
  0
  
  8:05 PM
  
  Mannheim
  Central Bus Station
  
  5:10 AM
  
  Lyon
  Perrache Train Station
  
  0
  
  Economy
  
  $30
  
  A Bus from BlaBlaCar Bus goes from Central Bus Station, Mannheim (Germany) at 7/29/2026 8:05:00 PM to Perrache Train Station, Lyon (France) arriving at 7/30/2026 5:10:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 9h 5m
Travel time is 0h 40m longer, but you will save $33

Best Price Offer: The price for the cheapest bus from Frankfurt am Main to Lyon is $44 on 8/18/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Frankfurt am Main and Lyon

See here how frequent the connections between Frankfurt am Main and Lyon are, during different times and days of the week.

Sunday is the busiest day, with more than 8 daily buses from Frankfurt am Main to Lyon. Monday has instead the fewest connections, with only 7 daily coaches between Frankfurt am Main and Lyon.

The busiest time of the day is the Evening, with 21 buses from Frankfurt am Main to Lyon, while Afternoon sees the fewest connections between Frankfurt am Main and Lyon, with 6 offers.

Facts about the bus from Frankfurt am Main to Lyon

Compare all providers like FlixBus and BlaBlaCar Bus that travel 7 times every day by bus from Frankfurt am Main to Lyon in one click! Book your bus ticket from Frankfurt am Main to Lyon starting from $44!

Cheapest Bus	$44
Fastest Bus	10h 0m
Earliest Bus	12:45 AM
Latest Bus	10:45 PM
Daily Bus Routes	7 Ø
Distance	349.5 miles
Bus Companies	FlixBus and BlaBlaCar Bus

Cheapest bus connections from Frankfurt am Main to Lyon

Every day, 7 buses from 2 bus companies leave Frankfurt am Main for Lyon: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/26/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/26

$149

Monday 07/27

$122

Tuesday 07/28

$108

Wednesday 07/29

$57

Thursday 07/30

$66

Friday 07/31

$66

Saturday 08/01

$71

Sunday 08/02

$57

Monday 08/03

$59

Tuesday 08/04

$104

Wednesday 08/05

$57

Thursday 08/06

$55

Friday 08/07

$57

Saturday 08/08

$66

Sunday 08/09

$63

Monday 08/10

$56

Tuesday 08/11

$52

Wednesday 08/12

$49

Thursday 08/13

$49

Friday 08/14

$51

Saturday 08/15

$56

Sunday 08/16

$55

Monday 08/17

$49

Tuesday 08/18

$44

Wednesday 08/19

$44

Thursday 08/20

$47

Friday 08/21

$51

Saturday 08/22

The cheapest time to travel from Frankfurt am Main to Lyon

See here on which day and which time of the day you can find the cheapest bus ticket from Frankfurt am Main to Lyon, for the next 30 days.

With a price starting from $44, Tuesday is the cheapest day for a bus from Frankfurt am Main to Lyon. Saturday instead is the most expensive day with prices starting from $56.

Night is the cheapest day time for bus tickets from Frankfurt am Main to Lyon, with $44. Afternoon is the most expensive time of the day with prices starting from $62.

How to save money travelling from Frankfurt am Main to Lyon

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Frankfurt am Main to Lyon in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Frankfurt am Main to Lyon, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Frankfurt am Main to Lyon are also emptier.

All bus stations and stops in Frankfurt am Main and Lyon

In the map below, you can see where to find all bus stations in Frankfurt am Main and Lyon.

Central Bus Station

Karlsruher Straße 10

Stuttgarter Strasse Bus Stop

Stuttgarter Str.

Seilerstraße Bus Stop

Stresemannallee/Mörfelder Landstr. Bus Stop

Baseler Platz Bus Stop

Perrache Bus Stop

Cours de Verdun 14

Saint Paul Train Station

Pont Kitchener R.G. Bus Stop

Cours de Verdun

Maison Carrée Bus Stop

Les Charrières 69570

Girondins - Yves Farge Bus Stop

Service and Comfort on the bus from Frankfurt am Main to Lyon

Want to know which seat classes are available on the buses from Frankfurt am Main to Lyon? Or which bus companies serve the route Frankfurt am Main to Lyon? Below you will find answers to your questions.

FAQs about the Frankfurt am Main to Lyon bus

How much does a Frankfurt am Main Lyon bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $44 and takes 10h 40m to reach Lyon. Compare offers to save money!

How much could I save by comparing buses from Frankfurt am Main to Lyon?

This route is offered by 2 companies with a range of ticket prices between $44 and $155. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Lyon.

On average, how many connections are available from Frankfurt am Main to Lyon each day?

Every day, the Frankfurt am Main to Lyon bus route is served by approximately 7 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Frankfurt am Main to Lyon take?

The fastest bus from Frankfurt am Main to Lyon is offered by FlixBus and takes 10h 0m. Bus tickets for this connection cost $90. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Frankfurt am Main to Lyon?

The earliest bus arriving in Lyon from Frankfurt am Main starts at 12:45 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Frankfurt am Main to Lyon?

The latest bus trip departing from Frankfurt am Main for Lyon starts at 10:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Frankfurt am Main Lyon route?

When traveling by bus from Frankfurt am Main to Lyon, passengers can travel with FlixBus and BlaBlaCar Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Frankfurt am Main and Lyon?

You can check all the direct connections between Frankfurt am Main and Lyon by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and BlaBlaCar Bus.

What can I take with me on the Frankfurt am Main to Lyon bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Frankfurt am Main Lyon bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Frankfurt am Main Lyon bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Frankfurt am Main to Lyon on your planned travel date.

How does CheckMyBus find the best bus deals from Frankfurt am Main to Lyon?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 7 daily trips between Frankfurt am Main and Lyon. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Frankfurt am Main to Lyon?

Prices and availability for 7 trips between Frankfurt am Main and Lyon change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Frankfurt am Main to Lyon

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Frankfurt am Main and to Lyon

Here’s an overview of the most popular bus routes to Frankfurt am Main and to Lyon. Simply click on the connection of your choice, and you will find all the details about your bus route!