Bus Denver to Knoxville, TN - Compare all Companies

Compare all timetables for the bus from Denver to Knoxville, TN

Here is a selection of the cheapest bus trips from the schedule from Denver to Knoxville, TN from various bus operators like Greyhound US for the next days.

today

$124

tomorrow

$117

Thursday

Friday

Saturday

$143

Sunday

$124

Monday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	30h 55m	1:35 PM	Denver	Union Station	10:30 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$124	A Bus from Greyhound US goes from Union Station, Denver (USA) at 9/8/2026 1:35:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 9/9/2026 10:30:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 30h 55m
Greyhound US	44h 20m	7:25 PM	Denver	Union Station	5:45 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$125	A Bus from Greyhound US goes from Union Station, Denver (USA) at 9/8/2026 7:25:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 9/10/2026 5:45:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 44h 20m
Greyhound US	45h 40m	8:10 PM	Denver	Union Station	7:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$125	A Bus from Greyhound US goes from Union Station, Denver (USA) at 9/8/2026 8:10:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 9/10/2026 7:50:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 45h 40m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	30h 55m	1:35 PM	Denver	Union Station	10:30 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$117	A Bus from Greyhound US goes from Union Station, Denver (USA) at 9/9/2026 1:35:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 9/10/2026 10:30:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 30h 55m
Greyhound US	44h 20m	7:25 PM	Denver	Union Station	5:45 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$118	A Bus from Greyhound US goes from Union Station, Denver (USA) at 9/9/2026 7:25:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 9/11/2026 5:45:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 44h 20m
Greyhound US	45h 40m	8:10 PM	Denver	Union Station	7:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$118	A Bus from Greyhound US goes from Union Station, Denver (USA) at 9/9/2026 8:10:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 9/11/2026 7:50:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 45h 40m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	44h 20m	7:25 PM	Denver	Union Station	5:45 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$143	A Bus from Greyhound US goes from Union Station, Denver (USA) at 9/12/2026 7:25:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 9/14/2026 5:45:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 44h 20m
Greyhound US	30h 55m	1:35 PM	Denver	Union Station	10:30 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$144	A Bus from Greyhound US goes from Union Station, Denver (USA) at 9/12/2026 1:35:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 9/13/2026 10:30:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 30h 55m
Greyhound US	45h 40m	8:10 PM	Denver	Union Station	7:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$152	A Bus from Greyhound US goes from Union Station, Denver (USA) at 9/12/2026 8:10:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 9/14/2026 7:50:00 PM. 50 Economy ticket for $152 per person are available. Travel duration is 45h 40m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	30h 55m	1:35 PM	Denver	Union Station	10:30 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$124	A Bus from Greyhound US goes from Union Station, Denver (USA) at 9/13/2026 1:35:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 9/14/2026 10:30:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 30h 55m
Greyhound US	45h 40m	8:10 PM	Denver	Union Station	7:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$125	A Bus from Greyhound US goes from Union Station, Denver (USA) at 9/13/2026 8:10:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 9/15/2026 7:50:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 45h 40m
Greyhound US	44h 20m	7:25 PM	Denver	Union Station	5:45 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$127	A Bus from Greyhound US goes from Union Station, Denver (USA) at 9/13/2026 7:25:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 9/15/2026 5:45:00 PM. 50 Economy ticket for $127 per person are available. Travel duration is 44h 20m

Best Price Offer: The price for the cheapest bus from Denver to Knoxville, TN is $91 on 9/28/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Denver and Knoxville, TN

See here how frequent the connections between Denver and Knoxville, TN are, during different times and days of the week.

Saturday is the busiest day, with more than 6 daily buses from Denver to Knoxville, TN. Sunday has instead the fewest connections, with only 3 daily coaches between Denver and Knoxville, TN.

The busiest time of the day is the Evening, with 10 buses from Denver to Knoxville, TN, while Afternoon sees the fewest connections between Denver and Knoxville, TN, with 5 offers.

Facts about the bus from Denver to Knoxville, TN

Compare all providers like Greyhound US that travel 3 times every day by bus from Denver to Knoxville, TN in one click! Book your bus ticket from Denver to Knoxville, TN starting from $91!

Cheapest Bus	$91
Fastest Bus	32h 55m
Earliest Bus	1:35 PM
Latest Bus	8:10 PM
Daily Bus Routes	3 Ø
Distance	1,176.8 miles
Bus Companies	Greyhound US

Cheapest bus connections from Denver to Knoxville, TN

Every day, 3 buses from 1 bus companies leave Denver for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/08/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 09/06

Monday 09/07

Tuesday 09/08

$124

Wednesday 09/09

$117

Thursday 09/10

Friday 09/11

Saturday 09/12

$147

Sunday 09/13

$124

Monday 09/14

Tuesday 09/15

Wednesday 09/16

$134

Thursday 09/17

Friday 09/18

$150

Saturday 09/19

Sunday 09/20

$147

Monday 09/21

$142

Tuesday 09/22

Wednesday 09/23

Thursday 09/24

$133

Friday 09/25

$129

Saturday 09/26

$122

Sunday 09/27

$113

Monday 09/28

$91

Tuesday 09/29

$122

Wednesday 09/30

$107

Thursday 10/01

$133

Friday 10/02

$139

Saturday 10/03

The cheapest time to travel from Denver to Knoxville, TN

See here on which day and which time of the day you can find the cheapest bus ticket from Denver to Knoxville, TN, for the next 30 days.

With a price starting from $107, Wednesday is the cheapest day for a bus from Denver to Knoxville, TN. Saturday instead is the most expensive day with prices starting from $122.

Afternoon is the cheapest day time for bus tickets from Denver to Knoxville, TN, with $117. Evening is the most expensive time of the day with prices starting from $118.

How to save money travelling from Denver to Knoxville, TN

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Denver to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Denver to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Denver to Knoxville, TN are also emptier.

All bus stations and stops in Denver and Knoxville, TN

In the map below, you can see where to find all bus stations in Denver and Knoxville, TN.

Federal Blvd & W 19th Ave Bus Stop

Federal Blvd & W 19th Ave Federal Blvd & W 19th Ave

Union Station

Wynkoop St 1701

Bus Stop

Colorado Station

E Evans Ave 4401

19th St. Bus Station

19th St 1055

Kingston Pike

Kingston Pike 6927

Knoxville Area Transit Bus Stop

Knoxville Area Transit Bus Stop Knoxville Area Transit Bus Stop

Walker Springs Plaza Shopping Center

Kingston Pike 8509

Greyhound Bus Station

E Magnolia Ave 100

Transit Center

E Church Ave 301

Service and Comfort on the bus from Denver to Knoxville, TN

Want to know which seat classes are available on the buses from Denver to Knoxville, TN? Or which bus companies serve the route Denver to Knoxville, TN? Below you will find answers to your questions.

FAQs about the Denver to Knoxville, TN bus

How much does a Denver Knoxville, TN bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $91 and takes 32h 55m to reach Knoxville, TN. Compare offers to save money!

How much could I save by comparing buses from Denver to Knoxville, TN?

This route is offered by 1 companies with a range of ticket prices between $91 and $156. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.

On average, how many connections are available from Denver to Knoxville, TN each day?

Every day, the Denver to Knoxville, TN bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Denver to Knoxville, TN take?

The fastest bus from Denver to Knoxville, TN is offered by Greyhound US and takes 32h 55m. Bus tickets for this connection cost $124. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Denver to Knoxville, TN?

The earliest bus arriving in Knoxville, TN from Denver starts at 1:35 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Denver to Knoxville, TN?

The latest bus trip departing from Denver for Knoxville, TN starts at 8:10 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Denver Knoxville, TN route?

When traveling by bus from Denver to Knoxville, TN, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Denver and Knoxville, TN?

You can check all the direct connections between Denver and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Denver to Knoxville, TN bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Denver Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Denver Knoxville, TN bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Denver to Knoxville, TN on your planned travel date.

How does CheckMyBus find the best bus deals from Denver to Knoxville, TN?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Denver and Knoxville, TN. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Denver to Knoxville, TN?

Prices and availability for 3 trips between Denver and Knoxville, TN change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Denver to Knoxville, TN

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Denver and to Knoxville, TN

Here’s an overview of the most popular bus routes to Denver and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!