Bus Calexico, CA to Santa Ana, CA - Compare all Companies

Compare all timetables for the bus from Calexico, CA to Santa Ana, CA

Here is a selection of the cheapest bus trips from the schedule from Calexico, CA to Santa Ana, CA from various bus operators like Greyhound US for the next days.

today

$45

tomorrow

$42

Tuesday

$41

Wednesday

Thursday

$33

Friday

$37

Saturday

$33

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	10h 20m	9:10 AM	Calexico, CA	Bus Station	7:30 PM	Santa Ana, CA	Bus Stop		Economy	$45	A Bus from Greyhound US goes from Bus Station, Calexico, CA (USA) at 7/26/2026 9:10:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 7/26/2026 7:30:00 PM. 50 Economy ticket for $45 per person are available. Travel duration is 10h 20m
	Greyhound US	6h 55m	2:40 PM	Calexico, CA	Bus Station	9:35 PM	Santa Ana, CA	Bus Stop		Economy	$46	A Bus from Greyhound US goes from Bus Station, Calexico, CA (USA) at 7/26/2026 2:40:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 7/26/2026 9:35:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 6h 55m

Did you know that if you travel from Calexico, CA to Santa Ana, CA via San Diego, you can save more than $7? You can find the corresponding connections below.
- Greyhound US
  
  6h 55m
  
  0
  
  2:40 PM
  
  Calexico, CA
  Bus Station
  
  5:45 PM
  
  San Diego
  Old Town Transit Center
  
  0
  
  Economy
  
  $21
  
  A Bus from Greyhound US goes from Bus Station, Calexico, CA (USA) at 7/27/2026 2:40:00 PM to Old Town Transit Center, San Diego (USA) arriving at 7/27/2026 5:45:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 3h 5m
- Greyhound US
  
  1h 40m
  
  0
  
  7:55 PM
  
  San Diego
  Old Town Transit Center
  
  9:35 PM
  
  Santa Ana, CA
  Bus Stop
  
  0
  
  Economy
  
  $17
  
  A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 7/27/2026 7:55:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 7/27/2026 9:35:00 PM. 50 Economy ticket for $17 per person are available. Travel duration is 1h 40m
Travel time is the same as the direct connection, but you will save $7

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	6h 55m	2:40 PM	Calexico, CA	Bus Station	9:35 PM	Santa Ana, CA	Bus Stop		Economy	$42	A Bus from Greyhound US goes from Bus Station, Calexico, CA (USA) at 7/27/2026 2:40:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 7/27/2026 9:35:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 6h 55m
	Greyhound US	10h 20m	9:10 AM	Calexico, CA	Bus Station	7:30 PM	Santa Ana, CA	Bus Stop		Economy	$43	A Bus from Greyhound US goes from Bus Station, Calexico, CA (USA) at 7/27/2026 9:10:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 7/27/2026 7:30:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 10h 20m

Did you know that if you travel from Calexico, CA to Santa Ana, CA via San Diego, you can save more than $4? You can find the corresponding connections below.
- Greyhound US
  
  6h 55m
  
  0
  
  2:40 PM
  
  Calexico, CA
  Bus Station
  
  5:45 PM
  
  San Diego
  Old Town Transit Center
  
  0
  
  Economy
  
  $21
  
  A Bus from Greyhound US goes from Bus Station, Calexico, CA (USA) at 7/27/2026 2:40:00 PM to Old Town Transit Center, San Diego (USA) arriving at 7/27/2026 5:45:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 3h 5m
- Greyhound US
  
  1h 40m
  
  0
  
  7:55 PM
  
  San Diego
  Old Town Transit Center
  
  9:35 PM
  
  Santa Ana, CA
  Bus Stop
  
  0
  
  Economy
  
  $17
  
  A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 7/27/2026 7:55:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 7/27/2026 9:35:00 PM. 50 Economy ticket for $17 per person are available. Travel duration is 1h 40m
Travel time is the same as the direct connection, but you will save $4

Cheapest bus trips Tuesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	10h 20m	9:10 AM	Calexico, CA	Bus Station	7:30 PM	Santa Ana, CA	Bus Stop		Economy	$41	A Bus from Greyhound US goes from Bus Station, Calexico, CA (USA) at 7/28/2026 9:10:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 7/28/2026 7:30:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 10h 20m
	Greyhound US	6h 55m	2:40 PM	Calexico, CA	Bus Station	9:35 PM	Santa Ana, CA	Bus Stop		Economy	$41	A Bus from Greyhound US goes from Bus Station, Calexico, CA (USA) at 7/28/2026 2:40:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 7/28/2026 9:35:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 6h 55m

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	6h 55m	2:40 PM	Calexico, CA	Bus Station	9:35 PM	Santa Ana, CA	Bus Stop		Economy	$33	A Bus from Greyhound US goes from Bus Station, Calexico, CA (USA) at 7/30/2026 2:40:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 7/30/2026 9:35:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 6h 55m
	Greyhound US	10h 20m	9:10 AM	Calexico, CA	Bus Station	7:30 PM	Santa Ana, CA	Bus Stop		Economy	$34	A Bus from Greyhound US goes from Bus Station, Calexico, CA (USA) at 7/30/2026 9:10:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 7/30/2026 7:30:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 10h 20m

Cheapest bus trips Friday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	6h 55m	2:40 PM	Calexico, CA	Bus Station	9:35 PM	Santa Ana, CA	Bus Stop		Economy	$37	A Bus from Greyhound US goes from Bus Station, Calexico, CA (USA) at 7/31/2026 2:40:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 7/31/2026 9:35:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 6h 55m
	Greyhound US	10h 20m	9:10 AM	Calexico, CA	Bus Station	7:30 PM	Santa Ana, CA	Bus Stop		Economy	$41	A Bus from Greyhound US goes from Bus Station, Calexico, CA (USA) at 7/31/2026 9:10:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 7/31/2026 7:30:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 10h 20m

Cheapest bus trips Saturday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	6h 55m	2:40 PM	Calexico, CA	Bus Station	9:35 PM	Santa Ana, CA	Bus Stop		Economy	$33	A Bus from Greyhound US goes from Bus Station, Calexico, CA (USA) at 8/1/2026 2:40:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 8/1/2026 9:35:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 6h 55m
	Greyhound US	10h 20m	9:10 AM	Calexico, CA	Bus Station	7:30 PM	Santa Ana, CA	Bus Stop		Economy	$36	A Bus from Greyhound US goes from Bus Station, Calexico, CA (USA) at 8/1/2026 9:10:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 8/1/2026 7:30:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 10h 20m

Best Price Offer: The price for the cheapest bus from Calexico, CA to Santa Ana, CA is $32 on 8/19/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Calexico, CA and Santa Ana, CA

See here how frequent the connections between Calexico, CA and Santa Ana, CA are, during different times and days of the week.

Saturday is the busiest day, with more than 4 daily buses from Calexico, CA to Santa Ana, CA. Sunday has instead the fewest connections, with only 2 daily coaches between Calexico, CA and Santa Ana, CA.

The busiest time of the day is the Morning, with 7 buses from Calexico, CA to Santa Ana, CA, while Morning sees the fewest connections between Calexico, CA and Santa Ana, CA, with 7 offers.

Facts about the bus from Calexico, CA to Santa Ana, CA

Compare all providers like Greyhound US that travel 2 times every day by bus from Calexico, CA to Santa Ana, CA in one click! Book your bus ticket from Calexico, CA to Santa Ana, CA starting from $32!

Cheapest Bus	$32
Fastest Bus	6h 55m
Earliest Bus	9:10 AM
Latest Bus	2:40 PM
Daily Bus Routes	2 Ø
Distance	155.6 miles
Bus Companies	Greyhound US

Cheapest bus connections from Calexico, CA to Santa Ana, CA

Every day, 2 buses from 1 bus companies leave Calexico, CA for Santa Ana, CA: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/26/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/26

$45

Monday 07/27

$42

Tuesday 07/28

$41

Wednesday 07/29

Thursday 07/30

$33

Friday 07/31

$37

Saturday 08/01

$37

Sunday 08/02

$42

Monday 08/03

Tuesday 08/04

$33

Wednesday 08/05

$37

Thursday 08/06

Friday 08/07

$42

Saturday 08/08

$40

Sunday 08/09

$46

Monday 08/10

Tuesday 08/11

$38

Wednesday 08/12

$33

Thursday 08/13

$38

Friday 08/14

Saturday 08/15

$38

Sunday 08/16

$40

Monday 08/17

Tuesday 08/18

$36

Wednesday 08/19

$32

Thursday 08/20

Friday 08/21

Saturday 08/22

The cheapest time to travel from Calexico, CA to Santa Ana, CA

See here on which day and which time of the day you can find the cheapest bus ticket from Calexico, CA to Santa Ana, CA, for the next 30 days.

With a price starting from $33, Tuesday is the cheapest day for a bus from Calexico, CA to Santa Ana, CA. Monday instead is the most expensive day with prices starting from $42.

Afternoon is the cheapest day time for bus tickets from Calexico, CA to Santa Ana, CA, with $33. Morning is the most expensive time of the day with prices starting from $34.

How to save money travelling from Calexico, CA to Santa Ana, CA

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Calexico, CA to Santa Ana, CA in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Calexico, CA to Santa Ana, CA, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Calexico, CA to Santa Ana, CA are also emptier.

All bus stations and stops in Calexico, CA and Santa Ana, CA

In the map below, you can see where to find all bus stations in Calexico, CA and Santa Ana, CA.

Bus Station

E 1St St 123

Gran Plaza Outlets

Bus Stop

1000 E Santa Ana Blvd 105

Service and Comfort on the bus from Calexico, CA to Santa Ana, CA

Want to know which seat classes are available on the buses from Calexico, CA to Santa Ana, CA? Or which bus companies serve the route Calexico, CA to Santa Ana, CA? Below you will find answers to your questions.

FAQs about the Calexico, CA to Santa Ana, CA bus

How much does a Calexico, CA Santa Ana, CA bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $32 and takes 6h 55m to reach Santa Ana, CA. Compare offers to save money!

How much could I save by comparing buses from Calexico, CA to Santa Ana, CA?

This route is offered by 1 companies with a range of ticket prices between $32 and $46. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santa Ana, CA.

On average, how many connections are available from Calexico, CA to Santa Ana, CA each day?

Every day, the Calexico, CA to Santa Ana, CA bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Calexico, CA to Santa Ana, CA take?

The fastest bus from Calexico, CA to Santa Ana, CA is offered by Greyhound US and takes 6h 55m. Bus tickets for this connection cost $46. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Calexico, CA to Santa Ana, CA?

The earliest bus arriving in Santa Ana, CA from Calexico, CA starts at 9:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Calexico, CA to Santa Ana, CA?

The latest bus trip departing from Calexico, CA for Santa Ana, CA starts at 2:40 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Calexico, CA Santa Ana, CA route?

When traveling by bus from Calexico, CA to Santa Ana, CA, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Calexico, CA and Santa Ana, CA?

You can check all the direct connections between Calexico, CA and Santa Ana, CA by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Calexico, CA to Santa Ana, CA bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Calexico, CA Santa Ana, CA bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Calexico, CA Santa Ana, CA bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Calexico, CA to Santa Ana, CA on your planned travel date.

How does CheckMyBus find the best bus deals from Calexico, CA to Santa Ana, CA?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Calexico, CA and Santa Ana, CA. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Calexico, CA to Santa Ana, CA?

Prices and availability for 2 trips between Calexico, CA and Santa Ana, CA change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Calexico, CA to Santa Ana, CA

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Calexico, CA and to Santa Ana, CA

Here’s an overview of the most popular bus routes to Calexico, CA and to Santa Ana, CA. Simply click on the connection of your choice, and you will find all the details about your bus route!