Bus Boston, MA to Charleston, SC - Compare all Companies

Compare all timetables for the bus from Boston, MA to Charleston, SC

Here is a selection of the cheapest bus trips from the schedule from Boston, MA to Charleston, SC from various bus operators like FlixBus or Greyhound US for the next days.

today

tomorrow

$149

Friday

$101

Saturday

$109

Sunday

$137

Monday

$98

Tuesday

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	35h 15m	1:00 AM	Boston, MA	South Station	12:15 PM	Charleston, SC	Bus Station	Economy	$149	A Bus from FlixBus goes from South Station, Boston, MA (USA) at 9/10/2026 1:00:00 AM to Bus Station, Charleston, SC (USA) arriving at 9/11/2026 12:15:00 PM. 50 Economy ticket for $149 per person are available. Travel duration is 35h 15m
FlixBus	38h 25m	9:50 PM	Boston, MA	South Station	12:15 PM	Charleston, SC	Bus Station	Economy	$155	A Bus from FlixBus goes from South Station, Boston, MA (USA) at 9/10/2026 9:50:00 PM to Bus Station, Charleston, SC (USA) arriving at 9/12/2026 12:15:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 38h 25m
FlixBus	25h 35m	8:15 PM	Boston, MA	South Station	9:50 PM	Charleston, SC	Bus Station	Economy	$158	A Bus from FlixBus goes from South Station, Boston, MA (USA) at 9/10/2026 8:15:00 PM to Bus Station, Charleston, SC (USA) arriving at 9/11/2026 9:50:00 PM. 50 Economy ticket for $158 per person are available. Travel duration is 25h 35m
Greyhound US	25h 45m	4:45 PM	Boston, MA	South Station	6:30 PM	Charleston, SC	Bus Station	Economy	$158	A Bus from Greyhound US goes from South Station, Boston, MA (USA) at 9/10/2026 4:45:00 PM to Bus Station, Charleston, SC (USA) arriving at 9/11/2026 6:30:00 PM. 50 Economy ticket for $158 per person are available. Travel duration is 25h 45m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	25h 45m	4:45 PM	Boston, MA	South Station	6:30 PM	Charleston, SC	Bus Station	Economy	$101	A Bus from Greyhound US goes from South Station, Boston, MA (USA) at 9/11/2026 4:45:00 PM to Bus Station, Charleston, SC (USA) arriving at 9/12/2026 6:30:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 25h 45m
FlixBus	28h 15m	8:00 AM	Boston, MA	South Station	12:15 PM	Charleston, SC	Bus Station	Economy	$105	A Bus from FlixBus goes from South Station, Boston, MA (USA) at 9/11/2026 8:00:00 AM to Bus Station, Charleston, SC (USA) arriving at 9/12/2026 12:15:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 28h 15m
FlixBus	34h 45m	1:30 AM	Boston, MA	Allston	12:15 PM	Charleston, SC	Bus Station	Economy	$114	A Bus from FlixBus goes from Allston, Boston, MA (USA) at 9/11/2026 1:30:00 AM to Bus Station, Charleston, SC (USA) arriving at 9/12/2026 12:15:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 34h 45m
FlixBus	38h 25m	9:50 PM	Boston, MA	South Station	12:15 PM	Charleston, SC	Bus Station	Economy	$118	A Bus from FlixBus goes from South Station, Boston, MA (USA) at 9/11/2026 9:50:00 PM to Bus Station, Charleston, SC (USA) arriving at 9/13/2026 12:15:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 38h 25m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	25h 45m	4:45 PM	Boston, MA	South Station	6:30 PM	Charleston, SC	Bus Station	Economy	$109	A Bus from Greyhound US goes from South Station, Boston, MA (USA) at 9/12/2026 4:45:00 PM to Bus Station, Charleston, SC (USA) arriving at 9/13/2026 6:30:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 25h 45m
FlixBus	34h 45m	1:30 AM	Boston, MA	Allston	12:15 PM	Charleston, SC	Bus Station	Economy	$111	A Bus from FlixBus goes from Allston, Boston, MA (USA) at 9/12/2026 1:30:00 AM to Bus Station, Charleston, SC (USA) arriving at 9/13/2026 12:15:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 34h 45m
FlixBus	38h 25m	9:50 PM	Boston, MA	South Station	12:15 PM	Charleston, SC	Bus Station	Economy	$119	A Bus from FlixBus goes from South Station, Boston, MA (USA) at 9/12/2026 9:50:00 PM to Bus Station, Charleston, SC (USA) arriving at 9/14/2026 12:15:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 38h 25m
FlixBus	25h 35m	8:15 PM	Boston, MA	South Station	9:50 PM	Charleston, SC	Bus Station	Economy	$122	A Bus from FlixBus goes from South Station, Boston, MA (USA) at 9/12/2026 8:15:00 PM to Bus Station, Charleston, SC (USA) arriving at 9/13/2026 9:50:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 25h 35m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	25h 45m	4:45 PM	Boston, MA	South Station	6:30 PM	Charleston, SC	Bus Station	Economy	$137	A Bus from Greyhound US goes from South Station, Boston, MA (USA) at 9/13/2026 4:45:00 PM to Bus Station, Charleston, SC (USA) arriving at 9/14/2026 6:30:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 25h 45m
FlixBus	38h 25m	9:50 PM	Boston, MA	South Station	12:15 PM	Charleston, SC	Bus Station	Economy	$143	A Bus from FlixBus goes from South Station, Boston, MA (USA) at 9/13/2026 9:50:00 PM to Bus Station, Charleston, SC (USA) arriving at 9/15/2026 12:15:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 38h 25m
FlixBus	28h 15m	8:00 AM	Boston, MA	South Station	12:15 PM	Charleston, SC	Bus Station	Economy	$151	A Bus from FlixBus goes from South Station, Boston, MA (USA) at 9/13/2026 8:00:00 AM to Bus Station, Charleston, SC (USA) arriving at 9/14/2026 12:15:00 PM. 50 Economy ticket for $151 per person are available. Travel duration is 28h 15m
FlixBus	34h 45m	1:30 AM	Boston, MA	Allston	12:15 PM	Charleston, SC	Bus Station	Economy	$155	A Bus from FlixBus goes from Allston, Boston, MA (USA) at 9/13/2026 1:30:00 AM to Bus Station, Charleston, SC (USA) arriving at 9/14/2026 12:15:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 34h 45m

Did you know that if you travel from Boston, MA to Charleston, SC via Myrtle Beach, SC, you can save more than $43? You can find the corresponding connections below.
- Greyhound US
  
  25h 45m
  
  0
  
  4:45 PM
  
  Boston, MA
  Atlantic and Beach St
  
  3:50 PM
  
  Myrtle Beach, SC
  Bus Stop
  
  0
  
  Economy
  
  $81
  
  A Bus from Greyhound US goes from Atlantic and Beach St, Boston, MA (USA) at 9/14/2026 4:45:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 9/15/2026 3:50:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 23h 5m
- Greyhound US
  
  2h 25m
  
  0
  
  4:05 PM
  
  Myrtle Beach, SC
  Bus Stop
  
  6:30 PM
  
  Charleston, SC
  Bus Station
  
  0
  
  Economy
  
  $12
  
  A Bus from Greyhound US goes from Bus Stop, Myrtle Beach, SC (USA) at 9/15/2026 4:05:00 PM to Bus Station, Charleston, SC (USA) arriving at 9/15/2026 6:30:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 2h 25m
Travel time is the same as the direct connection, but you will save $43

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	28h 15m	8:00 AM	Boston, MA	South Station	12:15 PM	Charleston, SC	Bus Station	Economy	$98	A Bus from FlixBus goes from South Station, Boston, MA (USA) at 9/14/2026 8:00:00 AM to Bus Station, Charleston, SC (USA) arriving at 9/15/2026 12:15:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 28h 15m
Greyhound US	25h 45m	4:45 PM	Boston, MA	South Station	6:30 PM	Charleston, SC	Bus Station	Economy	$100	A Bus from Greyhound US goes from South Station, Boston, MA (USA) at 9/14/2026 4:45:00 PM to Bus Station, Charleston, SC (USA) arriving at 9/15/2026 6:30:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 25h 45m
FlixBus	38h 25m	9:50 PM	Boston, MA	South Station	12:15 PM	Charleston, SC	Bus Station	Economy	$103	A Bus from FlixBus goes from South Station, Boston, MA (USA) at 9/14/2026 9:50:00 PM to Bus Station, Charleston, SC (USA) arriving at 9/16/2026 12:15:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 38h 25m
FlixBus	34h 45m	1:30 AM	Boston, MA	Allston	12:15 PM	Charleston, SC	Bus Station	Economy	$115	A Bus from FlixBus goes from Allston, Boston, MA (USA) at 9/14/2026 1:30:00 AM to Bus Station, Charleston, SC (USA) arriving at 9/15/2026 12:15:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 34h 45m

Did you know that if you travel from Boston, MA to Charleston, SC via Myrtle Beach, SC, you can save more than $10? You can find the corresponding connections below.
- Greyhound US
  
  25h 45m
  
  0
  
  4:45 PM
  
  Boston, MA
  South Station
  
  3:50 PM
  
  Myrtle Beach, SC
  Bus Stop
  
  0
  
  Economy
  
  $76
  
  A Bus from Greyhound US goes from South Station, Boston, MA (USA) at 9/15/2026 4:45:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 9/16/2026 3:50:00 PM. 50 Economy ticket for $76 per person are available. Travel duration is 23h 5m
- Greyhound US
  
  2h 25m
  
  0
  
  4:05 PM
  
  Myrtle Beach, SC
  Bus Stop
  
  6:30 PM
  
  Charleston, SC
  Bus Station
  
  0
  
  Economy
  
  $12
  
  A Bus from Greyhound US goes from Bus Stop, Myrtle Beach, SC (USA) at 9/16/2026 4:05:00 PM to Bus Station, Charleston, SC (USA) arriving at 9/16/2026 6:30:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 2h 25m
Travel time is the same as the direct connection, but you will save $10

Best Price Offer: The price for the cheapest bus from Boston, MA to Charleston, SC is $96 on 9/25/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Boston, MA and Charleston, SC

See here how frequent the connections between Boston, MA and Charleston, SC are, during different times and days of the week.

Sunday is the busiest day, with more than 6 daily buses from Boston, MA to Charleston, SC. Sunday has instead the fewest connections, with only 6 daily coaches between Boston, MA and Charleston, SC.

The busiest time of the day is the Evening, with 15 buses from Boston, MA to Charleston, SC, while Morning sees the fewest connections between Boston, MA and Charleston, SC, with 4 offers.

Facts about the bus from Boston, MA to Charleston, SC

Compare all providers like FlixBus and Greyhound US that travel 6 times every day by bus from Boston, MA to Charleston, SC in one click! Book your bus ticket from Boston, MA to Charleston, SC starting from $96!

Cheapest Bus	$96
Fastest Bus	25h 10m
Earliest Bus	1:00 AM
Latest Bus	9:50 PM
Daily Bus Routes	6 Ø
Distance	820.2 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Boston, MA to Charleston, SC

Every day, 6 buses from 2 bus companies leave Boston, MA for Charleston, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/09/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 09/06

Monday 09/07

Tuesday 09/08

Wednesday 09/09

Thursday 09/10

$149

Friday 09/11

$101

Saturday 09/12

$109

Sunday 09/13

$137

Monday 09/14

$98

Tuesday 09/15

Wednesday 09/16

Thursday 09/17

Friday 09/18

Saturday 09/19

Sunday 09/20

$107

Monday 09/21

Tuesday 09/22

Wednesday 09/23

Thursday 09/24

Friday 09/25

$96

Saturday 09/26

$118

Sunday 09/27

Monday 09/28

Tuesday 09/29

Wednesday 09/30

Thursday 10/01

Friday 10/02

Saturday 10/03

The cheapest time to travel from Boston, MA to Charleston, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Boston, MA to Charleston, SC, for the next 30 days.

With a price starting from $95, Sunday is the cheapest day for a bus from Boston, MA to Charleston, SC. Thursday instead is the most expensive day with prices starting from $149.

Night is the cheapest day time for bus tickets from Boston, MA to Charleston, SC, with $95. Evening is the most expensive time of the day with prices starting from $103.

How to save money travelling from Boston, MA to Charleston, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Boston, MA to Charleston, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Boston, MA to Charleston, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Boston, MA to Charleston, SC are also emptier.

All bus stations and stops in Boston, MA and Charleston, SC

In the map below, you can see where to find all bus stations in Boston, MA and Charleston, SC.

South Station

Atlantic Ave 700

Prudential Center T Transit Station

Huntington Ave 220

Sheraton Hotel

Dalton St 39

Copley Square

Boylston Street

Atlantic and Beach St

Atlantic Avenue 748

Bus Station

Dorchester Rd 3610

BI-LO Shopping Center Downtown

Meeting St 445

Service and Comfort on the bus from Boston, MA to Charleston, SC

Want to know which seat classes are available on the buses from Boston, MA to Charleston, SC? Or which bus companies serve the route Boston, MA to Charleston, SC? Below you will find answers to your questions.

FAQs about the Boston, MA to Charleston, SC bus

How much does a Boston, MA Charleston, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $96 and takes 28h 15m to reach Charleston, SC. Compare offers to save money!

How much could I save by comparing buses from Boston, MA to Charleston, SC?

This route is offered by 2 companies with a range of ticket prices between $96 and $175. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Charleston, SC.

On average, how many connections are available from Boston, MA to Charleston, SC each day?

Every day, the Boston, MA to Charleston, SC bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Boston, MA to Charleston, SC take?

The fastest bus from Boston, MA to Charleston, SC is offered by FlixBus and takes 25h 10m. Bus tickets for this connection cost $158. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Boston, MA to Charleston, SC?

The earliest bus arriving in Charleston, SC from Boston, MA starts at 1:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Boston, MA to Charleston, SC?

The latest bus trip departing from Boston, MA for Charleston, SC starts at 9:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Boston, MA Charleston, SC route?

When traveling by bus from Boston, MA to Charleston, SC, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Boston, MA and Charleston, SC?

You can check all the direct connections between Boston, MA and Charleston, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Boston, MA to Charleston, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Boston, MA Charleston, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Boston, MA Charleston, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Boston, MA to Charleston, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Boston, MA to Charleston, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Boston, MA and Charleston, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Boston, MA to Charleston, SC?

Prices and availability for 6 trips between Boston, MA and Charleston, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Boston, MA to Charleston, SC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Boston, MA and to Charleston, SC

Here’s an overview of the most popular bus routes to Boston, MA and to Charleston, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!